Activities in Family	Poly α-D-N-acetylgalactosaminuric acid lyase (EC 4.2.2.-); Pectin lyase (EC 4.2.2.10); Pectate lyase (EC 4.2.2.2); Exo-polygalacturonate lyase (EC 4.2.2.9);
Mechanism	b-elimination
3D Structure Status	parallel β-helix
External resources	CAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (14742); Uniprot accession (122); PDB accession (47); 3D entries (17); cryst (1)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
poly α-D-N-acetylgalactosaminuric acid lyase (VexL; AdVexL)	4.2.2.-	Achromobacter denitrificans CWG1240	ANB43583.1	A0A160EBC2	6FI2[A] α-D-GalpANAc-(1-4)-α-D-GalpANAc3Ac-(1-4)-α-D-GalpANAc3Ac 1.22	13
pectate lyase (PelA; Bsp165PelA)	4.2.2.2	Bacillus sp. N16-5	ACY38198.1	D0VP31	3VMV[A] 1.54 3VMW[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-D-1-deoxy-GalpA 1.90	5
pectate lyase (Pl47)	4.2.2.2	Bacillus sp. TS-47	BAB40336.1 CAW61498.1 CAW70664.1 CBC41559.1 CBC59844.1	Q9AJM4	1VBL[A] 1.91	6
pectate lyase (Pel;Pel168;BSU07560)	4.2.2.2	Bacillus subtilis subsp. subtilis str. 168	CAB12585.1 AAR45489.1 AIY92046.1 AQR80710.1 AQR84923.1 CAD67509.1 CAD67510.1 CAD67511.1 CAF05441.1 CAW61552.1 CAW70718.1 CBC41660.1 CBC59954.1 NP_388637.1	A0A6M4JL16 P39116	1BN8[A] 1.80 2BSP[A] 1.80 2NZM[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 1.80 2O04[A] α-D-GalpA-(1-4)-α-D-GalpA 1.70 2O0V[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 1.90 2O0W[A] 1.90 2O17[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 2.30 2O1D[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 2.00 3KRG[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 1.90 5AMV[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 1.57 5X2I[A] 2.05	6
pectate lyase (PelA)	4.2.2.2	Dickeya chrysanthemi EC16	AAA24843.1 CAW40921.1 CAW46079.1 CAW49283.1 CAW50990.1 CAW61547.1 CAW62451.1 CAW70713.1 CAW71339.1 CAW73819.1 CAW79796.1 CAW89319.1 CAW91254.1 CAW91911.1 CAW96011.1 CAW96232.1 CAW97078.1 CAX02155.1 CAX06725.1 CAX07079.1 CAX07582.1 CBC11581.1 CBC98482.1	P0C1A2 P29155	1JRG[A,B] 2.10 1JTA[A] 1.80 1OOC[A,B] 2.94 1PE9[A,B] 1.60	6
pectate lyase (PelC)	4.2.2.2	Dickeya chrysanthemi EC16	AAA24849.1 AAR45490.1 AAW11900.1	P11073	1AIR[A] 2.20 1O88[A] 2.2 1O8D[A] 2.2 1O8E[A] 2.2 1O8F[A] 2.2 1O8G[A] 2.2 1O8H[A] 2.2 1O8I[A] 2.2 1O8J[A] 2.2 1O8K[A] 2.2 1O8L[A] 2.2 1O8M[A] 2.2 1PLU[A] 2.20 2EWE[A] α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 2.20 2PEC[A] 2.20	3
pectate lyase (PelE)	4.2.2.2	Dickeya chrysanthemi EC16	AAA24844.1 CAW40923.1 CAW46081.1 CAW49285.1 CAW50992.1 CAW61550.1 CAW62453.1 CAW70716.1 CAW71341.1 CAW73821.1 CAW79798.1 CAW89324.1 CAW91258.1 CAW91916.1 CAW96013.1 CAW96234.1 CAW97080.1 CAX02157.1 CAX06727.1 CAX07081.1 CAX07584.1 CBC11583.1 CBC98486.1	P04960	1PCL[A] 2.20	6
pectate lyase (PelN)	4.2.2.2	Paenibacillus sp. 0602	AGM38211.1	W8CR80	5GT5[A,B] 1.45
pectate lyase (Pel;AcPel;Aave_3434)		Paracidovorax citrulli AAC00-1	ABM33991.1		4HWV[A,B] 1.37	6
RB5312 (Pel)		Rhodopirellula baltica SH 1	CAD74167.1 NP_866628.1		cryst	2
pectate lyase (PelA; BacPelA)	4.2.2.2	Shouchella clausii S10	ALK03050.1	A0A0P0J4R7	7XKS[A] 1.78	5
exo-pectate lyase A (PelA; TM0433)	4.2.2.2	Thermotoga maritima MSB8	AAD35518.1 AGL49355.1 AHD17809.1 AKE28227.1 CAW40843.1 CAW46001.1 CAW49205.1 CAW50912.1 CAW61439.1 CAW62373.1 CAW70605.1 CAW71261.1 CAW73741.1 CAW79718.1 CAW89134.1 CAW91082.1 CAW91782.1 CAW95933.1 CAW96154.1 CAW97000.1 CAX02077.1 CAX06647.1 CAX07001.1 CAX07504.1 CBC11503.1 CBC98340.1 NP_228243.1	G4FHZ2 Q9WYR4	3ZSC[A] α-D-4-deoxy-GlcpA-(1-4)-α-D-GalpA-(1-4)-α-D-GalpA 1.94
pectate lyase II (PelB;XCC2815)	4.2.2.2	Xanthomonas campestris pv. campestris str. ATCC 33913	AAM42087.1 NP_638163.1	Q8P6Z9	2QX3[A,B] 2.00 2QXZ[A,B] 2.12 2QY1[A,B] 1.90	3
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
pectin lyase A (PelA) (Pl1A)	4.2.2.10	Aspergillus niger CBS 120.49 / N400	CAA43130.1 CAA39305.1	Q01172	1IDJ[A,B] 2.40 1IDK[A] 1.93	4
pectin lyase B (PelB)	4.2.2.10	Aspergillus niger CBS 120.49 / N400	CAA46521.1 CAA01023.1	Q00205	1QCX[A] 1.70	4
allergen 1-1 (Jun a 1;Juna1)		Juniperus ashei	AAD03608.1 AAD03609.1 ABE16436.1 CAW40649.1 CAW40898.1 CAW46056.1 CAW49260.1 CAW50967.1 CAW61362.1 CAW61519.1 CAW62428.1 CAW70685.1 CAW71316.1 CAW73796.1 CAW74489.1 CAW77364.1 CAW79773.1 CAW81648.1 CAW89266.1 CAW91204.1 CAW91867.1 CAW95988.1 CAW96209.1 CAW97055.1 CAX02132.1 CAX06702.1 CAX07056.1 CAX07559.1 CBC11558.1 CBC98441.1		1PXZ[A,B] 1.70	1
pectate lyase (VdPelB; VDAG_04718)	4.2.2.2	Verticillium dahliae VdLs.17	XP_009652617.1	G2X3Y1	7BBV[A,B] 1.20	7
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