Polysaccharide Lyase Family 1

Known Activities	pectate lyase (EC 4.2.2.2); exo-pectate lyase (EC 4.2.2.9); pectin lyase (EC 4.2.2.10).
3D Structure Status	parallel β-helix
External resources	HOMSTRAD; InterPro; PFAM;
Commercial Enzyme Provider(s)	PROZOMIX;
Statistics	GenBank accession (4007); Uniprot accession (554); PDB accession (37); 3D entries (11); cryst (2)

Summary

All (852) Archaea (9) Bacteria (484) Eukaryota (357) unclassified (2) Structure (11 - 2 cryst) Characterized (94) Subfamilies (651)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
pectate lyase	4.2.2.2	Bacillus agaradhaerens	AAE59745.1 AAS29292.1			5
pectate lyase	4.2.2.2	Bacillus halodurans	AAE59748.1 AAS29295.1			5
pectate lyase (Pel-4B;BH3819)	4.2.2.2	Bacillus halodurans C-125	BAB07538.1 CAW61441.1 CAW70607.1 CBC41450.1 CBC59731.1 NP_244686.1	Q9K6B0		5
pectate lyase (Pel-4A;BH0698)	4.2.2.2	Bacillus halodurans C-125	BAB04417.1 CAW40844.1 CAW46002.1 CAW49206.1 CAW50913.1 CAW61440.1 CAW62374.1 CAW70606.1 CAW71262.1 CAW73742.1 CAW79719.1 CAW89137.1 CAW91084.1 CAW91785.1 CAW95934.1 CAW96155.1 CAW97001.1 CAX02078.1 CAX06648.1 CAX07002.1 CAX07505.1 CBC11504.1 CBC98341.1 NP_241564.1	Q9KF01
pectate lyase (PelA)	4.2.2.2 4.2.2.9	Bacillus licheniformis 14A	AAE59746.1 AAN26179.1 AAS29293.1 ACP63662.1 CAD56882.1	Q8GCB2		5
BLi04129 or BL00947 (PelII)	4.2.2.2 4.2.2.9	Bacillus licheniformis ATCC 14580 / DSM13	AAU25568.1 AAU42942.1 CAW40854.1 CAW46012.1 CAW49216.1 CAW50923.1 CAW61466.1 CAW62384.1 CAW70632.1 CAW71272.1 CAW73752.1 CAW79729.1 CAW89163.1 CAW91107.1 CAW91806.1 CAW95944.1 CAW96165.1 CAW97011.1 CAX02088.1 CAX06658.1 CAX07012.1 CAX07515.1 CBC11514.1 CBC98361.1	Q65DC2		5
pectate lyase (Pel)	4.2.2.2	Bacillus licheniformis RN1	BAG12908.1	Q8GCB2		5
pectate lyase (Pel-22)	4.2.2.2	Bacillus pumilus BS22	ADK23889.1	D8X181		5
pectate lyase (PelB)	4.2.2.2	Bacillus pumilus DKS1	ACD11362.1	B2ZFM0		5
pectate lyase	4.2.2.2	Bacillus sp. AAI12	AAE59747.1 AAS29294.1			5
pectate lyase	4.2.2.9	Bacillus sp. I534	AAE59749.1 AAR65348.1 AAS29296.1			5
pectate lyase (Pel-103)	4.2.2.2	Bacillus sp. KSM-P103	BAA76885.1 CAW61508.1 CAW70674.1 CBC41578.1 CBC59865.1	Q9WX56		5
pectate lyase (Pel7;Pel-7) (fragment)	4.2.2.2	Bacillus sp. KSM-P7	BAA76884.1	Q9XE02		5
pectate lyase (PelA) (fragment)	4.2.2.2	Bacillus sp. N16-5	ACY38198.1	D0VP31		5
pectate lyase (Pel-34K)	4.2.2.2 4.2.2.9	Bacillus sp. P-2850	BAC11008.1	Q8L0S6		5
pectate lyase (Pel-4B)	4.2.2.2	Bacillus sp. P-4-N	BAA96478.1	Q9NDN1		5
pectate lyase (Pel-4A)	4.2.2.2	Bacillus sp. P-4-N	BAA96477.1	Q9NDN2
pectate lyase (Pl47)	4.2.2.2	Bacillus sp. TS-47	BAB40336.1 CAW61498.1 CAW70664.1 CBC41559.1 CBC59844.1	Q9AJM4	1VBL[A]	6
pectate lyase (PelK)	4.2.2.2	Bacillus sp. YA-14	BAA05383.1	Q6LEQ4		6
pectate lyase (Pel)	4.2.2.2	Bacillus subtilis AC327	BAA22313.1	P39116		6
pectate lyase (Pel-66)	4.2.2.2	Bacillus subtilis BS66	ADK23888.1	D8X180		6
pectin lyase (Ppr)	4.2.2.10	Bacillus subtilis IFO 3134	BAA12119.1 CAW40861.1 CAW46019.1 CAW49223.1 CAW50930.1 CAW61472.1 CAW62391.1 CAW70638.1 CAW71279.1 CAW73759.1 CAW79736.1 CAW89178.1 CAW91125.1 CAW91820.1 CAW95951.1 CAW96172.1 CAW97018.1 CAX02095.1 CAX06665.1 CAX07019.1 CAX07522.1 CBC11521.1 CBC98374.1	P94449		8
pectate lyase (Pel)	4.2.2.2	Bacillus subtilis SO113	CAA52866.1	P39116		6
pectate lyase (Pel;BSU07560)	4.2.2.2	Bacillus subtilis subsp. subtilis str. 168	AAR45489.1 CAB12585.1 CAD67509.1 CAD67510.1 CAD67511.1 CAF05441.1 CAW61552.1 CAW70718.1 CBC41660.1 CBC59954.1 NP_388637.1	P39116	1BN8[A] 2BSP[A] 2NZM[A] 2O04[A] 2O0V[A] 2O0W[A] 2O17[A] 2O1D[A] 3KRG[A]	6
pectate lyase D (PelD;PLd;Dda3937_03372)	4.2.2.2	Dickeya dadantii 3937	ADM99552.1 CAA10570.1 CAW40891.1 CAW46049.1 CAW49253.1 CAW50960.1 CAW61511.1 CAW62421.1 CAW70677.1 CAW71309.1 CAW73789.1 CAW79766.1 CAW89250.1 CAW91190.1 CAW91860.1 CAW95981.1 CAW96202.1 CAW97048.1 CAX02125.1 CAX06695.1 CAX07049.1 CAX07552.1 CBC11551.1 CBC98428.1	E0SAZ3 Q9Z4J4		6
pectate lyase Z (PelZ;Dda3937_04191)	4.2.2.2	Dickeya dadantii 3937	ADN00347.1 CAA65785.1	E0SJQ8 P94773		2
pectate lyase C (PelC;PLc;Dda3937_04192)	4.2.2.2	Dickeya dadantii 3937	ADN00346.1 CAA10642.1 CAA47822.1	E0SJQ7 Q59420 Q79AJ0		3
pectate lyase E (PelE;PLe;Dda3937_03371)	4.2.2.2	Dickeya dadantii 3937	AAA24854.1 ADM99551.1	P0C1A5		6
pectate lyase A (PelA;Dda3937_03370)	4.2.2.2	Dickeya dadantii 3937	AAA24846.1 ADM99550.1	P0C1A3		6
pectate lyase B (PelB;Dda3937_04193)	4.2.2.2	Dickeya dadantii 3937	ADN00345.1 CAA47821.1 S25262	E0SJQ6 Q59419		3
pectate lyase D (PelD)	4.2.2.2	Erwinia chrysanthemi B374	CAA35176.1 CAW40922.1 CAW46080.1 CAW49284.1 CAW50991.1 CAW61549.1 CAW62452.1 CAW70715.1 CAW71340.1 CAW73820.1 CAW79797.1 CAW89321.1 CAW91256.1 CAW91914.1 CAW96012.1 CAW96233.1 CAW97079.1 CAX02156.1 CAX06726.1 CAX07080.1 CAX07583.1 CBC11582.1 CBC98484.1	P18209.1		6
pectate lyase E (PelE)	4.2.2.2	Erwinia chrysanthemi B374	CAA35175.1 CAW40924.1 CAW46082.1 CAW49286.1 CAW50993.1 CAW61551.1 CAW62454.1 CAW70717.1 CAW71342.1 CAW73822.1 CAW79799.1 CAW89327.1 CAW91260.1 CAW91918.1 CAW96014.1 CAW96235.1 CAW97081.1 CAX02158.1 CAX06728.1 CAX07082.1 CAX07585.1 CBC11584.1 CBC98488.1	P0C1A4 P18210		6
pectate lyase (PelA)	4.2.2.2	Erwinia chrysanthemi EC16	AAA24843.1 CAW40921.1 CAW46079.1 CAW49283.1 CAW50990.1 CAW61547.1 CAW62451.1 CAW70713.1 CAW71339.1 CAW73819.1 CAW79796.1 CAW89319.1 CAW91254.1 CAW91911.1 CAW96011.1 CAW96232.1 CAW97078.1 CAX02155.1 CAX06725.1 CAX07079.1 CAX07582.1 CBC11581.1 CBC98482.1	P0C1A2 P29155	1JRG[A,B] 1JTA[A] 1OOC[A,B] 1PE9[A,B]	6
pectate lyase (PelB;PlB)	4.2.2.2	Erwinia chrysanthemi EC16	AAA24847.1	P04959.1		3
pectate lyase (PelC)	4.2.2.2	Erwinia chrysanthemi EC16	AAA24849.1 AAR45490.1 AAW11900.1	P11073.1	1AIR[A] 1O88[A] 1O8D[A] 1O8E[A] 1O8F[A] 1O8G[A] 1O8H[A] 1O8I[A] 1O8J[A] 1O8K[A] 1O8L[A] 1O8M[A] 1PLU[A] 2EWE[A] 2PEC[A]	3
pectate lyase (PelE)	4.2.2.2	Erwinia chrysanthemi EC16	AAA24844.1 CAW40923.1 CAW46081.1 CAW49285.1 CAW50992.1 CAW61550.1 CAW62453.1 CAW70716.1 CAW71341.1 CAW73821.1 CAW79798.1 CAW89324.1 CAW91258.1 CAW91916.1 CAW96013.1 CAW96234.1 CAW97080.1 CAX02157.1 CAX06727.1 CAX07081.1 CAX07584.1 CBC11583.1 CBC98486.1	P04960.1	1PCL[A]	6
pectate lyase (Pel-90)	4.2.2.2	Lysinibacillus fusiformis BS90	ADK23887.1	D8X179		6
ECA4067 (PelA)	4.2.2.2	Pectobacterium atrosepticum SCRI1043	CAG76964.1			3
pectate lyase (Pel-1;Pel1)	4.2.2.2	Pectobacterium carotovorum 71	AAA73933.1	Q47467		3
Pel9.5 (fragment)	4.2.2.2	Pectobacterium carotovorum EC14	CAA43402.1	Q04086		3
pectin lyase (PnlA) (fragment)	4.2.2.10	Pectobacterium carotovorum ECC71	AAA24856.1	Q02726		8
pectate lyase III (Pel3;PelC)	4.2.2.2	Pectobacterium carotovorum ER	BAA00953.1	P0C1C2 P29171		3
pectin lyase (Pnl)	4.2.2.10	Pectobacterium carotovorum ER	AAA24857.1 CAW61559.1 CAW70725.1 CBC41674.1 CBC59969.1	P24112.1		8
pectate lyase 1 (Pel1;PelI)	4.2.2.2	Pectobacterium carotovorum ER / IAM1068 / ATROSEPTICA EC / ATROSEPTICA C18	AAA24845.1 AAC60423.1 BAA00155.1 CAA57439.1	P0C1C0 P11430		3
pectate lyase 2 (Pel2;PelII)	4.2.2.2	Pectobacterium carotovorum ER / IAM1068 / ATROSEPTICA EC / ATROSEPTICA C18	AAA24848.1 AAC60422.1 CAA57440.1	P0C1C1 P11431		3
pectate lyase B (PelB)	4.2.2.2	Pseudoalteromonas haloplanktis 505	AAF86343.1 AAF86343.2	Q9KGY6		5
pectate lyase A (PelA)	4.2.2.2	Pseudoalteromonas haloplanktis ANT/505	AAF86344.2	Q9KGY5		5
pectate lyase (Pel)	4.2.2.2	Pseudomonas fluorescens CY091	AAA93535.1 AAB46399.1	Q59671.1		6
pectate lyase (PeL)	4.2.2.2	Pseudomonas marginalis N6301	AAC60448.1 BAA06848.1 CAW61554.1 CAW70720.1 CBC41664.1 CBC59958.1	Q51915.1		6
pectin lyase (PnL)	4.2.2.10	Pseudomonas marginalis N6301	AAA92512.1 BAA06847.1	P27027.2 Q51914		8
pectate lyase P (PelP)	4.2.2.2	Pseudomonas syringae pv. lachrymans	AAB17879.1	P72242		6
pectate lyase (Pel;Pstru-4)	4.2.2.2	Pseudomonas viridiflava	AAB46398.1 AAC41521.1 ABB55454.1 BAA08077.1 CAW61556.1 CAW70722.1 CBC41668.1 CBC59963.1	Q60140.1		6
pectate lyase (Pel)	4.2.2.2	Pseudonocardia sp.	AAC38059.1 CAW40858.1 CAW46016.1 CAW49220.1 CAW50927.1 CAW61470.1 CAW62388.1 CAW70636.1 CAW71276.1 CAW73756.1 CAW79733.1 CAW89172.1 CAW91119.1 CAW91814.1 CAW95948.1 CAW96169.1 CAW97015.1 CAX02092.1 CAX06662.1 CAX07016.1 CAX07519.1 CBC11518.1 CBC98368.1	O08454
pectate lyase (SCO1880;SCI39.27c)	4.2.2.2	Streptomyces coelicolor A3(2)	CAC38815.1 CAW61443.1 CAW70609.1 CBC41453.1 CBC59735.1 NP_626147.1	Q93RU6		6
pectate lyase (SCO2821;SCBAC17F8.12c)	4.2.2.2	Streptomyces coelicolor A3(2)	CAC44284.1 NP_627050.1	Q93J76		5
pectate lyase A (PelA;TM0433)	4.2.2.2	Thermotoga maritima MSB8	AAD35518.1 CAW40843.1 CAW46001.1 CAW49205.1 CAW50912.1 CAW61439.1 CAW62373.1 CAW70605.1 CAW71261.1 CAW73741.1 CAW79718.1 CAW89134.1 CAW91082.1 CAW91782.1 CAW95933.1 CAW96154.1 CAW97000.1 CAX02077.1 CAX06647.1 CAX07001.1 CAX07504.1 CBC11503.1 CBC98340.1 NP_228243.1	Q9WYR4	cryst
XC_1298	4.2.2.2	Xanthomonas campestris pv. campestris str. 8004	AAY48367.1	Q4UX56
XC_3590	4.2.2.2	Xanthomonas campestris pv. campestris str. 8004	AAY50632.1	Q4UQP1		6
pectate lyase (Pel;XCC0645)	4.2.2.2	Xanthomonas campestris pv. campestris str. ATCC 33913	AAM39961.1 CAW61445.1 CBC41457.1 CBC59739.1 NP_636037.1			6
pectate lyase II (PelB;XCC2815)	4.2.2.2	Xanthomonas campestris pv. campestris str. ATCC 33913	AAM42087.1 NP_638163.1		2QX3[A,B] 2QXZ[A,B] 2QY1[A,B]
pectate lyase (PelB;Pl;Pstru-3)	4.2.2.2	Xanthomonas campestris PV. MALVACEARUM STRAIN B414	AAC41522.1	Q56806		6
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
pectate lyase (AN7646.2)	4.2.2.2	Aspergillus nidulans FGSC A4	ABF50889.1 CAW61463.1 CAW70629.1 CBC41490.1 CBC59776.1 EAA61832.1	C8VBZ5		7
pectin lyase (PL1;AN2569.2)	4.2.2.10	Aspergillus nidulans FGSC A4	ABF50856.1 EAA64674.1			4
pectin lyase (AN2331.2)	4.2.2.10	Aspergillus nidulans FGSC A4	ABF50854.1 EAA64442.1			4
pectate lyase (PelA;AN0741.2)	4.2.2.2	Aspergillus nidulans FGSC A4	AAA80568.1 ABF50844.1 ABO38859.1 CAW40920.1 CAW46078.1 CAW49282.1 CAW50989.1 CAW61546.1 CAW62450.1 CAW70712.1 CAW71338.1 CAW73818.1 CAW79795.1 CAW89317.1 CAW91252.1 CAW91909.1 CAW96010.1 CAW96231.1 CAW97077.1 CAX02154.1 CAX06724.1 CAX07078.1 CAX07581.1 CBC11580.1 CBC98480.1 EAA65383.1	Q00645		7
pectin lyase F (PelF)	4.2.2.10	Aspergillus niger CBS 120.49 / N400	CAD34589.1	Q8NJK6		4
pectin lyase C (PelC)	4.2.2.10	Aspergillus niger CBS 120.49 / N400	AAW03313.1	Q5MBK3		4
pectin lyase A (PelA) (Pl1A)	4.2.2.10	Aspergillus niger CBS 120.49 / N400	CAA39305.1 CAA43130.1	Q01172	1IDJ[A,B] 1IDK[A]	4
pectin lyase B (PelB)	4.2.2.10	Aspergillus niger CBS 120.49 / N400	CAA01023.1 CAA46521.1	Q00205	1QCX[A]	4
pectate lyase A (PlyA)	4.2.2.2	Aspergillus niger CBS 120.49 / N400	CAC33162.1 CAW40883.1 CAW46041.1 CAW49245.1 CAW50952.1 CAW62413.1 CAW71301.1 CAW73781.1 CAW79758.1 CAW89232.1 CAW91172.1 CAW91852.1 CAW95973.1 CAW96194.1 CAW97040.1 CAX02117.1 CAX06687.1 CAX07041.1 CAX07544.1 CBC11543.1 CBC98415.1	Q9C2Z0		7
An03g00190 (PelB)	4.2.2.10	Aspergillus niger CBS 513.88	CAK37997.1	A2QFN7		4
pectate lyase I (PlyA;An10g00870)	4.2.2.2	Aspergillus niger CBS 513.88	CAK40523.1	A2QV36		7
An14g04370 (PelA)	4.2.2.10	Aspergillus niger CBS 513.88	CAK48529.1	A2R3I1		4
An15g07160 (PelF)	4.2.2.10	Aspergillus niger CBS 513.88	CAK48551.1	A2R6A1		4
An19g00270 (PelD)	4.2.2.10	Aspergillus niger CBS 513.88	CAK47350.1	A2RBL2		4
pectin lyase D (PelD)	4.2.2.10	Aspergillus niger N756	AAA32701.1	P22864.1		4
pectin lyase 2 (Pel2)	4.2.2.10	Aspergillus oryzae KBN616	BAB82468.1	Q2TXS4 Q8X1X1		4
pectin lyase 1 (Pel1)	4.2.2.10	Aspergillus oryzae KBN616	BAB82467.1	Q2TWM1 Q8X1X2		4
pectin lyase 2 (Pel2;AO090010000030)	4.2.2.10	Aspergillus oryzae RIB40	BAE65949.1			4
pectin lyase 1 (Pel1;AO090010000504)	4.2.2.10	Aspergillus oryzae RIB40	ABO38857.1 BAE66352.1			4
pectin lyase (PnlA)	4.2.2.10	Colletotrichum gloeosporioides	AAA21817.1	Q00374		4
pectate lyase 1 (Pel-1)	4.2.2.2	Colletotrichum gloeosporioides f. sp. malvae	AAD43564.1 CAW61510.1 CAW70676.1 CBC41582.1 CBC59869.1	Q9Y892		7
pectate lyase 2 (Pel-2)	4.2.2.2	Colletotrichum gloeosporioides f. sp. malvae	AAD43566.1 CAW61509.1 CAW70675.1 CBC41580.1 CBC59867.1	Q9Y890		7
pectin lyase 2 (Pnl2;Pnl-2)	4.2.2.10	Colletotrichum gloeosporioides f. sp. malvae	AAD43565.1	Q9Y891		4
pectin lyase (Pnl1;Pnl-1)	4.2.2.10	Colletotrichum gloeosporioides f. sp. malvae	AAF22244.1	Q9UUS4		4
pectate lyase B (PelB;Plb)	4.2.2.2	Glomerella cingulata	AAD09857.1 CBC59946.1	O59939.1		7
pectin lyase 2 (Pnl2;ClPNL2)	4.2.2.10	Glomerella lindemuthiana 1472	AER38398.1 AER38399.1			4
pectate lyase (LLP-52)	4.2.2.2	Lilium longiflorum	AAA33398.1 ABM68553.1 CAA78976.1 CAV27791.1 CAW40678.1 CAW40925.1 CAW46083.1 CAW49287.1 CAW50994.1 CAW61388.1 CAW61553.1 CAW62455.1 CAW70719.1 CAW71343.1 CAW73823.1 CAW74515.1 CAW77390.1 CAW79800.1 CAW81674.1 CAW89329.1 CAW91262.1 CAW91920.1 CAW96015.1 CAW96236.1 CAW97082.1 CAX02159.1 CAX06729.1 CAX07083.1 CAX07586.1 CBC11585.1 CBC98490.1	P40973		1
pectate lyase (PelI;Pl1;MwPl1;Ban17)	4.2.2.2	Musa acuminata AAA Group	AAF19195.1 ABG74583.1 CAA63496.1 CAV27777.1 CAW40641.1 CAW40890.1 CAW46048.1 CAW49252.1 CAW50959.1 CAW61354.1 CAW61507.1 CAW62420.1 CAW70673.1 CAW71308.1 CAW73788.1 CAW74481.1 CAW77356.1 CAW79765.1 CAW81640.1 CAW89247.1 CAW91188.1 CAW91859.1 CAW95980.1 CAW96201.1 CAW97047.1 CAX02124.1 CAX06694.1 CAX07048.1 CAX07551.1 CBC11550.1 CBC98426.1	Q43783 Q9SDW4		1
pectate lyase	4.2.2.2	Nicotiana tabacum	CAA43414.1 CAA47630.1 CAA47631.1 CAW40679.1 CAW40926.1 CAW46084.1 CAW49288.1 CAW50995.1 CAW61389.1 CAW61557.1 CAW62456.1 CAW70723.1 CAW71344.1 CAW73824.1 CAW74516.1 CAW77391.1 CAW79801.1 CAW81675.1 CAW89332.1 CAW91265.1 CAW91922.1 CAW96016.1 CAW96237.1 CAW97083.1 CAX02160.1 CAX06730.1 CAX07084.1 CAX07587.1 CBC11586.1 CBC98492.1	P40972		1
pectin lyase (Plg1)	4.2.2.10	Penicillium griseoroseum	AAM23008.1	Q8NKE4		4
pectate lyase 1 (Pel1)	4.2.2.2	Penicillium occitanis CT1	ADK25712.1	D9ZX92		7
pectate lyase (Pcpel2)	4.2.2.10	Phytophthora capsici	ACR19247.1			4
pectate lyase	4.2.2.2	Zinnia violacea	CAA70735.1 CAC05181.1 CAV27756.1 CAW40680.1 CAW40927.1 CAW46085.1 CAW49289.1 CAW50996.1 CAW61390.1 CAW61558.1 CAW62457.1 CAW70724.1 CAW71345.1 CAW73825.1 CAW74517.1 CAW77392.1 CAW79802.1 CAW81676.1 CAW89335.1 CAW91267.1 CAW91924.1 CAW96017.1 CAW96238.1 CAW97084.1 CAX02161.1 CAX06731.1 CAX07085.1 CAX07588.1 CBC11587.1 CBC98494.1	O24554.1		1

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.