Polysaccharide Lyase Family 17 / Subf 2

Activities in Sub FamilyAlginate lyase (EC 4.2.2.-);
Oligomannuronate lyase / exo-acting mannuronan lyase (EC 4.2.2.-);
Poly-(MG)-lyase / MG-specific alginate lyase (EC 4.2.2.-);
Oligoalginate lyase / exo-alginate lyase (EC 4.2.2.26);
Poly(β-mannuronate) lyase / M-specific alginate lyase (EC 4.2.2.3);
Mechanism b-elimination
3D Structure Status( α / α ) 6 toroid + anti-parallel β-sheet
NoteThe alginate lyase function has been shown for several members of the family
External resourcesCAZypedia;
Statistics GenBank accession (1); Uniprot accession (14); PDB accession (7); 3D entries (3); cryst (0)
Bacteria
Protein Name EC# OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
Subf
 M-specific alginate lyase (BoPL17; OU990_24725) 4.2.2.3 Bacteroides ovatus CP926 WII03611.1  
8BDD[A,B] 1.61
2
 oligomannuronate lyase / oligoalginate lyase (Sde_3284) (Alg17C) 4.2.2.- Saccharophagus degradans 2-40 ABD82539.1
ACK10580.1
Q21FJ0
4NEI[A,B] 1.85
4OJZ[A,B] β-D-4-deoxy-ManpA-(1-4)-β-D-ManpA-(1-4)-α-L-GulpA
1.90
4OK2[A,B] 2.45
4OK4[A,B] 1.70
2
 polyM-specific alginate lyase (zobellia_2624; Alya3) 4.2.2.3 Zobellia galactanivorans DsijT CAZ96774.1 G0LCA3
7BJT[A,B] 1.42
7BM6[A,B] α-L-4-deoxy-AllpA-(1-4)-α-D-ManpA
2.16
2
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