Activities in Family	Hyaluronate lyase (EC 4.2.2.1);
Mechanism	b-elimination
3D Structure Status	triple strand β-helix
Note	Formerly known as glycoside hydrolase family GH69; assigned to a PL family following papers by Baker, J. R., Dong, S. and Pritchard, D. G. (2002) Biochem J 365, 317-322 and Smith et al (2005) PNAS 102: 17652-17657. Subfamilies have been removed in this family (December 2012).
Commercial Enzyme Provider(s)	PROZOMIX;
Statistics	GenBank accession (435); Uniprot accession (3); PDB accession (13); 3D entries (5); cryst (0)

Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
BV0002_038		Streptococcus phage BV-0002	WDS50820.1
Javan177_0009		Streptococcus phage Javan177	QBX15195.1
Javan183_0045		Streptococcus phage Javan183	QBX15374.1
Javan184_0046		Streptococcus phage Javan184	QBX24365.1
Javan185_0009		Streptococcus phage Javan185	QBX15391.1
Javan186_0046		Streptococcus phage Javan186	QBX24419.1
Javan187_0001		Streptococcus phage Javan187	QBX15437.1
Javan188_0009		Streptococcus phage Javan188	QBX24436.1
Javan189_0009		Streptococcus phage Javan189	QBX15487.1
Javan196_0009		Streptococcus phage Javan196	QBX24600.1
Javan446_0013		Streptococcus phage Javan446	QBX28227.1
Javan447_0011 (fragment)		Streptococcus phage Javan447	QBX18817.1
Javan448_0010		Streptococcus phage Javan448	QBX28292.1
Javan450_0008		Streptococcus phage Javan450	QBX28328.1
Javan451_0008		Streptococcus phage Javan451	QBX18871.1
Javan452_0056		Streptococcus phage Javan452	QBX28427.1
Javan456_0055		Streptococcus phage Javan456	QBX28549.1
Javan457_0008		Streptococcus phage Javan457	QBX18923.1
Javan459_0046		Streptococcus phage Javan459	QBX19005.1
Javan460_0042		Streptococcus phage Javan460	QBX28707.1
Javan464_0013		Streptococcus phage Javan464	QBX28728.1
Javan465_0007		Streptococcus phage Javan465	QBX19020.1
Javan467_0045		Streptococcus phage Javan467	QBX19106.1
Javan470_0046		Streptococcus phage Javan470	QBX28828.1
Javan472_0044		Streptococcus phage Javan472	QBX28881.1
Javan474_0009		Streptococcus phage Javan474	QBX28899.1
Javan476_0047		Streptococcus phage Javan476	QBX28998.1
Javan477_0047		Streptococcus phage Javan477	QBX19273.1
Javan481_0042		Streptococcus phage Javan481	QBX19323.1
Javan483_0010		Streptococcus phage Javan483	QBX19342.1
Javan484_0012		Streptococcus phage Javan484	QBX29146.1
Javan485_0010		Streptococcus phage Javan485	QBX19400.1
Javan486_0012		Streptococcus phage Javan486	QBX29217.1
Javan487_0010		Streptococcus phage Javan487	QBX19456.1
Javan488_0041		Streptococcus phage Javan488	QBX29306.1
Javan489_0053		Streptococcus phage Javan489	QBX19549.1
Javan491_0045		Streptococcus phage Javan491	QBX19637.1
Javan492_0049 (fragment)		Streptococcus phage Javan492	QBX29363.1
Javan493_0009 (fragment)		Streptococcus phage Javan493	QBX19656.1
Javan494_0009 (fragment)		Streptococcus phage Javan494	QBX29383.1
Javan496_0012 (fragment)		Streptococcus phage Javan496	QBX29437.1
Javan496_0013 (fragment)		Streptococcus phage Javan496	QBX29438.1
Javan497_0041		Streptococcus phage Javan497	QBX19747.1
Javan498_0010		Streptococcus phage Javan498	QBX29484.1
Javan501_0056		Streptococcus phage Javan501	QBX19914.1
Javan502_0010		Streptococcus phage Javan502	QBX29532.1
Javan507_0047		Streptococcus phage Javan507	QBX20078.1
Javan508_0010 (fragment)		Streptococcus phage Javan508	QBX29633.1
Javan508_0011 (fragment)		Streptococcus phage Javan508	QBX29634.1
Javan509_0008		Streptococcus phage Javan509	QBX20098.1
Javan511_0012		Streptococcus phage Javan511	QBX20188.1
Javan512_0012		Streptococcus phage Javan512	QBX29752.1
Javan520_0010		Streptococcus phage Javan520	QBX29998.1
Javan521_0049		Streptococcus phage Javan521	QBX20461.1
Javan522_0052		Streptococcus phage Javan522	QBX30097.1
Javan523_0011		Streptococcus phage Javan523	QBX20480.1
Javan525_0046		Streptococcus phage Javan525	QBX20576.1
Javan526_0055		Streptococcus phage Javan526	QBX30214.1
Javan527_0011		Streptococcus phage Javan527	QBX20595.1
Javan528_0044		Streptococcus phage Javan528	QBX30266.1
Javan530_0050		Streptococcus phage Javan530	QBX30322.1
Javan531_0042		Streptococcus phage Javan531	QBX20777.1
Javan532_0011 (fragment)		Streptococcus phage Javan532	QBX30345.1
Javan532_0010 (fragment)		Streptococcus phage Javan532	QBX30344.1
MissB1_0012 (fragment)		Streptococcus phage MissB1	UJD17837.1
MissC_0063 (fragment)		Streptococcus phage MissC	UJD17956.1
MissE1_0012 (fragment)		Streptococcus phage MissE1	UJD18031.1
MissF_0012 (fragment)		Streptococcus phage MissF	UJQ44939.1
MissG1_0008 (fragment)		Streptococcus phage MissG1	UJH95058.1
hylauronidase		Streptococcus phage P9	ABL61072.1
hyaluronidase		Streptococcus phage phiNIH1.1	AAL15086.1 NP_438157.1
hyaluronate lyase (HylP1;HylP)	4.2.2.1	Streptococcus pyogenes phage H4489A	AAA98101.1	P15316	6WV2[A,B,C] 6WWX[A,B,C] 6WXA[A,B,C] 6X3M[A,B,C,D,E,F,G,H,I]
SEA_ALONE_86		Streptomyces phage Alone3	WPH58274.1
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