Polysaccharide Lyase Family 16

Activities in Familyhyaluronan lyase (EC 4.2.2.1).
3D Structure Statustriple strand β-helix
NoteFormerly known as glycoside hydrolase family GH69; assigned to a PL family following papers by Baker, J. R., Dong, S. and Pritchard, D. G. (2002) Biochem J 365, 317-322 and Smith et al (2005) PNAS 102: 17652-17657. Subfamilies have been deleted in this family (December 2012).
Commercial Enzyme Provider(s)PROZOMIX;
Statistics GenBank accession (248); Uniprot accession (29); PDB accession (10); 3D entries (5); cryst (0)
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Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 NCTC12046_01123   Streptococcus pyogenes NCTC12046 SQF19794.1    
 NCTC12047_01474 (HylP)   Streptococcus pyogenes NCTC12047 SQF21921.1    
 NCTC12050_01298 (Hylp3)   Streptococcus pyogenes NCTC12050 SQF16328.1    
 NCTC12050_01007   Streptococcus pyogenes NCTC12050 SQF16048.1    
 NCTC12052_00638   Streptococcus pyogenes NCTC12052 SQF51859.1    
 NCTC12052_01240   Streptococcus pyogenes NCTC12052 SQF52445.1    
 NCTC12052_01068 (fragment)   Streptococcus pyogenes NCTC12052 SQF52274.1    
 NCTC12052_01796 (Hylp3)   Streptococcus pyogenes NCTC12052 SQF52973.1    
 NCTC12057_01008   Streptococcus pyogenes NCTC12057 SQF10000.1    
 NCTC12059_01062   Streptococcus pyogenes NCTC12059 SQE78906.1    
 NCTC12059_00688   Streptococcus pyogenes NCTC12059 SQE78165.1    
 NCTC12062_01065   Streptococcus pyogenes NCTC12062 SQF27880.1    
 NCTC12062_00694   Streptococcus pyogenes NCTC12062 SQF27065.1    
 NCTC12064_00395   Streptococcus pyogenes NCTC12064 SQF22579.1    
 NCTC12066_00784   Streptococcus pyogenes NCTC12066 SQE93017.1    
 NCTC12067_01393   Streptococcus pyogenes NCTC12067 SQF56221.1    
 NCTC12069_01456   Streptococcus pyogenes NCTC12069 SQF04216.1    
 NCTC12069_01116   Streptococcus pyogenes NCTC12069 SQF03893.1    
 NCTC12696_01300   Streptococcus pyogenes NCTC12696 SQF12883.1    
 NCTC12696_01102   Streptococcus pyogenes NCTC12696 SQF12699.1    
 NCTC12696_01531 (HylP)   Streptococcus pyogenes NCTC12696 SQF13111.1    
 NCTC12840_00523   Streptococcus pyogenes NCTC12840 SQF36052.1    
 NCTC12840_00765   Streptococcus pyogenes NCTC12840 SQF36483.1    
 NCTC13738_00863   Streptococcus pyogenes NCTC13738 SQG19575.1    
 NCTC13739_00681   Streptococcus pyogenes NCTC13739 SQH08627.1    
 NCTC13743_01037   Streptococcus pyogenes NCTC13743 SQG22800.1    
 NCTC13744_01109   Streptococcus pyogenes NCTC13744 SQG73318.1    
 NCTC13744_01447   Streptococcus pyogenes NCTC13744 SQG73639.1    
 NCTC13745_00583   Streptococcus pyogenes NCTC13745 SQH47662.1    
 NCTC13751_01255   Streptococcus pyogenes NCTC13751 SQH62852.1    
 NCTC4001_00660 (HylP)   Streptococcus pyogenes NCTC4001 SQF50225.1    
 NCTC4001_00483 (fragment)   Streptococcus pyogenes NCTC4001 SQF50049.1    
 NCTC4001_00482 (fragment)   Streptococcus pyogenes NCTC4001 SQF50048.1    
 NCTC5163_00807   Streptococcus pyogenes NCTC5163 SQE56134.1    
 NCTC5163_01047   Streptococcus pyogenes NCTC5163 SQE56631.1    
 NCTC5163_01287   Streptococcus pyogenes NCTC5163 SQE57170.1    
 NCTC5163_01116   Streptococcus pyogenes NCTC5163 SQE56772.1    
 NCTC5164_01287   Streptococcus pyogenes NCTC5164 SQE90839.1    
 NCTC5164_01116   Streptococcus pyogenes NCTC5164 SQE90669.1    
 NCTC5164_01047   Streptococcus pyogenes NCTC5164 SQE90600.1    
 NCTC5164_00807   Streptococcus pyogenes NCTC5164 SQE90364.1    
 NCTC8195_01159   Streptococcus pyogenes NCTC8195 SQF45658.1    
 NCTC8195_00718   Streptococcus pyogenes NCTC8195 SQF44848.1    
 NCTC8195_01539   Streptococcus pyogenes NCTC8195 SQF46440.1    
 NCTC8195_00622 (Hylp3)   Streptococcus pyogenes NCTC8195 SQF44680.1    
 NCTC8195_00263   Streptococcus pyogenes NCTC8195 SQF43881.1    
 ERS445054_01453   Streptococcus pyogenes NCTC8198 CKH05333.1    
 ERS445054_00613   Streptococcus pyogenes NCTC8198 CKG82209.1    
 ERS445054_01307 (HylP)   Streptococcus pyogenes NCTC8198 CKH01474.1    
 ERS445054_00899   Streptococcus pyogenes NCTC8198 CKG90139.1    
 NCTC8224_01063 (Hylp3)   Streptococcus pyogenes NCTC8224 SRX91036.1    
 NCTC8224_00721 (Hylp_2) (fragment)   Streptococcus pyogenes NCTC8224 SRX90699.1    
 NCTC8224_00577   Streptococcus pyogenes NCTC8224 SRX90557.1    
 NCTC8224_00720 (Hylp_1) (fragment)   Streptococcus pyogenes NCTC8224 SRX90698.1    
 NCTC8225_01005   Streptococcus pyogenes NCTC8225 SQE38596.1    
 NCTC8225_00555   Streptococcus pyogenes NCTC8225 SQE38162.1    
 NCTC8225_00286   Streptococcus pyogenes NCTC8225 SQE37903.1    
 NCTC8227_00965   Streptococcus pyogenes NCTC8227 SQG52357.1    
 NCTC8227_01293   Streptococcus pyogenes NCTC8227 SQG53079.1    
 NCTC8227_01143   Streptococcus pyogenes NCTC8227 SQG52623.1    
 NCTC8230_01627   Streptococcus pyogenes NCTC8230 SQF61520.1    
 NCTC8230_01119   Streptococcus pyogenes NCTC8230 SQF60518.1    
 NCTC8230_01291 (HylP)   Streptococcus pyogenes NCTC8230 SQF60840.1    
 NCTC8230_00272   Streptococcus pyogenes NCTC8230 SQF58692.1    
 NCTC8230_00863   Streptococcus pyogenes NCTC8230 SQF60040.1    
 NCTC8231_01010   Streptococcus pyogenes NCTC8231 SQF32808.1    
 NCTC8300_01412   Streptococcus pyogenes NCTC8300 SQF02499.1    
 NCTC8300_01000   Streptococcus pyogenes NCTC8300 SQF02100.1    
 NCTC8304_01007   Streptococcus pyogenes NCTC8304 SQG96868.1    
 NCTC8314_00747 (Hylp3)   Streptococcus pyogenes NCTC8314 SQE92822.1    
 NCTC8320_00629   Streptococcus pyogenes NCTC8320 SQG42580.1    
 NCTC8320_01067 (Hylp_1)   Streptococcus pyogenes NCTC8320 SQG43352.1    
 NCTC8320_01248 (Hylp_2)   Streptococcus pyogenes NCTC8320 SQG43724.1    
 NCTC8320_01517   Streptococcus pyogenes NCTC8320 SQG44323.1    
 NCTC8322_00564   Streptococcus pyogenes NCTC8322 SRX87147.1    
 NCTC8322_01260   Streptococcus pyogenes NCTC8322 SRX87813.1    
 NCTC8324_00424   Streptococcus pyogenes NCTC8324 SQF38000.1    
 NCTC8324_01001   Streptococcus pyogenes NCTC8324 SQF38584.1    
 NCTC8324_00823   Streptococcus pyogenes NCTC8324 SQF38407.1    
 NCTC8326_00684   Streptococcus pyogenes NCTC8326 SQF57170.1    
 NCTC8326_01331   Streptococcus pyogenes NCTC8326 SQF57802.1    
 NCTC8328_00784   Streptococcus pyogenes NCTC8328 SQF09662.1    
 NCTC8328_00395   Streptococcus pyogenes NCTC8328 SQF08894.1    
 NCTC8332_01047   Streptococcus pyogenes NCTC8332 SQF17824.1    
 NCTC8332_01287   Streptococcus pyogenes NCTC8332 SQF18063.1    
 NCTC8332_01116   Streptococcus pyogenes NCTC8332 SQF17893.1    
 NCTC8332_00807   Streptococcus pyogenes NCTC8332 SQF17588.1    
 SD89_06270   Streptococcus pyogenes NGAS322 AKZ50707.1    
 SD89_06945   Streptococcus pyogenes NGAS322 AKZ50836.1    
 SD89_05005   Streptococcus pyogenes NGAS322 AKZ50471.1    
 DK93_03885   Streptococcus pyogenes NGAS327 AKI38591.1    
 DK92_05065   Streptococcus pyogenes NGAS596 AKI37192.1    
 SD90_04815   Streptococcus pyogenes NGAS638 AKZ52250.1    
 DI45_04145   Streptococcus pyogenes NGAS743 AKI35205.1    
 DI45_03205   Streptococcus pyogenes NGAS743 AKI35031.1    
 C5P47_05700   Streptococcus pyogenes NGAS979 AWS23441.1    
 Spy49_0785   Streptococcus pyogenes NZ131 ACI61098.1 B5XL86  
 Spy49_1465c   Streptococcus pyogenes NZ131 ACI61737.1 B5XI75  
 SPs0763   Streptococcus pyogenes SSI-1 BAC63858.1
NP_802025.1
Q878Y7  
 SPs0927   Streptococcus pyogenes SSI-1 BAC64022.1
NP_802189.1
Q878T2  
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