Polysaccharide Lyase Family 12

Known Activities	heparin-sulfate lyase (EC 4.2.2.8)
Statistics	GenBank accession (164); Uniprot accession (79);

Summary

All (138) Bacteria (138) Characterized (2) Subfamilies (106)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
CbC4_1804+CbC4_1805		Clostridium botulinum BKT015925	AEB76478.1 AEB76479.1			1
CPF_0406		Clostridium perfringens ATCC 13124	ABG82423.1	Q0TU27		1
CPR_0402		Clostridium perfringens SM101	ABG87833.1	Q0SVW9		1
Cphy_3022		Clostridium phytofermentans ISDg	ABX43379.1	A9KQ67		1
Closa_4172		Clostridium saccharolyticum WM1	ADL06674.1	D9R2Q0		1
EF62_0996 (fragment)		Enterococcus faecalis 62	ADX79247.1			1
ERH_1218		Erysipelothrix rhusiopathiae str. Fujisawa	BAK32272.1			1
LSEI_2662		Lactobacillus casei ATCC 334	ABJ71381.1	Q034J1		1
LCBD_2878		Lactobacillus casei BD-II	AEA58372.1			1
LCABL_28520		Lactobacillus casei BL23	CAQ67902.1	B3WB33		1
LC2W_2852		Lactobacillus casei LC2W	AEA55181.1			1
LCAZH_2660		Lactobacillus casei str. Zhang	ADK19848.1	D8GDH1		1
LRHK_2791 (fragment)		Lactobacillus rhamnosus ATCC 8530	AER65509.1			1
LC705_02682		Lactobacillus rhamnosus Lc 705	CAR91521.1	C7TMT7		1
GYMC10_2636		Paenibacillus sp. Y412MC10	ACX64907.1	D3EB18		1
SpiBuddy_0862		Spirochaeta sp. Buddy	ADY12689.1			1
Spico_1386		Spirochaeta coccoides DSM 17374	AEC02590.1			1
Spico_1734		Spirochaeta coccoides DSM 17374	AEC02932.1			1
Smon_0124 (fragment)		Streptobacillus moniliformis DSM 12112	ACZ00617.1	D1AWE1		1
SAG1897		Streptococcus agalactiae 2603V/R serotype V	AAN00759.1 NP_688886.1			1
Gbs1885		Streptococcus agalactiae NEM316 serovar III	CAD47544.1 NP_736319.1			1
SDE12394_03460		Streptococcus dysgalactiae subsp. equisimilis ATCC 12394	ADX24212.1			1
SDEG_0643		Streptococcus dysgalactiae subsp. equisimilis GGS_124	BAH81145.1	C5WFI0		1
Sequence 4021 from patent US 6699703		Streptococcus pneumoniae	AAT16651.1 AAW08509.1 ABI03982.1 ABI09023.1 ABJ32539.1 ABJ50152.1 ABL17895.1 ACK14441.1 ACW45160.1			1
SP670_0396		Streptococcus pneumoniae 670-6B	ADM90471.1	E0TRK8		1
SP70585_0391		Streptococcus pneumoniae 70585	ACO16103.1	C1CBA6		1
SPAP_0359		Streptococcus pneumoniae AP200	ADM83952.1	E0SVH3		1
SPN23F03010		Streptococcus pneumoniae ATCC 700669	CAR68159.1	B8ZL46		1
SPCG_0333		Streptococcus pneumoniae CGSP14	ACB89585.1	B2ISP8		1
SPG_0297		Streptococcus pneumoniae G54	ACF55971.1	B5E6Y6		1
SPH_0438		Streptococcus pneumoniae Hungary19A-6	ACA37451.1	B1I947		1
INV104_02730		Streptococcus pneumoniae INV104	CBW35957.1	E1XPF9		1
SPNINV200_02940		Streptococcus pneumoniae INV200	CBW33928.1	E1XHY6		1
SPJ_0322		Streptococcus pneumoniae JJA	ACO18061.1	C1CCA3		1
SPNOXC_03370		Streptococcus pneumoniae OXC141	CBW31997.1	E1XEN9		1
SPP_0362		Streptococcus pneumoniae P1031	ACO20582.1	C1CIJ2		1
Spr0297		Streptococcus pneumoniae R6	AAK99101.1 NP_357891.1	Q8CZ74		1
MYY_0409		Streptococcus pneumoniae ST556	AFC94071.1			1
SPT_0376		Streptococcus pneumoniae Taiwan19F-14	ACO23038.1	C1CPK2		1
HMPREF0837_10630		Streptococcus pneumoniae TCH8431/19A	ADI68858.1	D6ZQG9		1
SP0327 (probable fragment)		Streptococcus pneumoniae TIGR4	AAK74503.1 NP_344863.1	Q97SK5		1
SPYALAB49_000550		Streptococcus pyogenes Alab49	AEQ24154.1			1
SPy0628		Streptococcus pyogenes M1 GAS SF370	AAK33596.1 NP_268875.1	Q9A0T7		1
M6_Spy0539		Streptococcus pyogenes MGAS10394	AAT86674.1			1
MGAS10750_Spy0537		Streptococcus pyogenes MGAS10750	ABF37487.1	Q1J7M4		1
MGAS15252_0544		Streptococcus pyogenes MGAS15252	AFC65895.1			1
MGAS1882_0541		Streptococcus pyogenes MGAS1882	AFC67764.1			1
MGAS2096_Spy0530		Streptococcus pyogenes MGAS2096	ABF35582.1	Q1JCS6		1
SpyM3_0442		Streptococcus pyogenes MGAS315	AAM79049.1 NP_664246.1	Q8K866		1
M5005_Spy_0518		Streptococcus pyogenes MGAS5005	AAZ51136.1			1
M28_Spy0497		Streptococcus pyogenes MGAS6180	AAX71611.1			1
SpyM18_0693		Streptococcus pyogenes MGAS8232	AAL97364.1 NP_606865.1	Q8P1V6		1
MGAS9429_Spy0509		Streptococcus pyogenes MGAS9429	ABF31697.1	Q1JMQ2		1
Spy49_0524c		Streptococcus pyogenes NZ131	ACI60852.1	B5XKJ0		1
SPs1413		Streptococcus pyogenes SSI-1	BAC64508.1 NP_802675.1			1
SpyM51345		Streptococcus pyogenes str. Manfredo	CAM30673.1	A2RFP4		1
SSU05_1211		Streptococcus suis 05ZYH33	ABP90177.1	A4VVN8		1
SSU98_1226		Streptococcus suis 98HAH33	ABP92384.1	A4W1Z5		1
SSUA7_1062		Streptococcus suis A7	AER44384.1			1
SSUBM407_0738		Streptococcus suis BM407	CAZ55570.1	C6GXM2		1
SSUD9_1368		Streptococcus suis D9	AER17554.1			1
SSGZ1_1067		Streptococcus suis GZ1	ADE31524.1	D5AI59		1
SSU1048		Streptococcus suis P1/7	CAR46189.1	C5VX48		1
SSUSC84_1086		Streptococcus suis SC84	CAZ51862.1	C6GNU0		1
SSU12_1114		Streptococcus suis SS12	AER15297.1			1
SSUST1_0750		Streptococcus suis ST1	AER21134.1			1
SSUST3_1224		Streptococcus suis ST3	AEB81649.1			1
AL1_01210		Alistipes shahii WAL 8301	CBK62838.1	D4IIS6		2
AL1_01260		Alistipes shahii WAL 8301	CBK62842.1	D4IIT0		2
AL1_01270 (fragment)		Alistipes shahii WAL 8301	CBK62843.1	D4IIT1		2
AL1_01890 (fragment)		Alistipes shahii WAL 8301	CBK62900.1	D4IIY8		2
Bache_1616		Bacteroides helcogenes P 36-108 ATCC 35417	ADV43619.1			2
heparinase III / heparin lyase III (HepIII)	4.2.2.8	Bacteroides stercoris HJ-15	ACT66689.1	C7EXL6		2
BT4662		Bacteroides thetaiotaomicron VPI-5482	AAO79767.1 NP_813573.1			2
BT4657		Bacteroides thetaiotaomicron VPI-5482	AAO79762.1 NP_813568.1			2
BXY_37640		Bacteriodes xylanisolvens XB1A	CBK68723.1	D6D2S1		2
BXY_37690		Bacteriodes xylanisolvens XB1A	CBK68728.1	D6D2S6		2
heparin-sulfate lyase / heparinase III (HepC;Phep_3797)	4.2.2.8	Pedobacter heparinus DSM 2366	AAB18278.1 ACH00306.1 ACK26501.1 ACU05988.1	C6XUY0 Q59289		2
Pedsa_1818		Pedobacter saltans DSM 12145	ADY52373.1			2
Pedsa_1814		Pedobacter saltans DSM 12145	ADY52369.1			2
RAM_02835		Amycolatopsis mediterranei S699	AEK39059.1			3
AMED_0553		Amycolatopsis mediterranei U32	ADJ42373.1	D8HZ18		3
ANT_24620		Anaerolinea thermophila UNI-1	BAJ64488.1			3
A2cp1_1481		Anaeromyxobacter dehalogenans 2CP-1	ACL64825.1	B8JHC3		3
Adeh_2473		Anaeromyxobacter dehalogenans 2CP-C	ABC82243.1	Q2IKR1		3
AnaeK_1385		Anaeromyxobacter sp. K	ACG72616.1	B4UJ55		3
BRADO7043		Bradyrhizobium sp. ORS278	CAL80627.1	A4Z3A1		3
CAP2UW1_0857 (fragment)		Candidatus Accumulibacter phosphatis clade IIA str. UW-1	ACV34195.1	C7RNQ9		3
Acid345_3793		Candidatus Koribacter versatilis Ellin345	ABF42793.1	Q1IK07		3
NIDE3009		Candidatus Nitrospira defluvii	CBK42705.1	D8PHG8		3
Acid_7470		Solibacter usitatus Ellin6076	ABJ88378.1	Q01PP2		3
Ctha_1213		Chloroherpeton thalassium ATCC 35110	ACF13677.1	B3QYY4		3
Ctha_2022		Chloroherpeton thalassium ATCC 35110	ACF14474.1	B3QUX3		3
NT01CX_1535		Clostridium novyi NT	ABK60682.1	A0PZ14		3
CPF_0471		Clostridium perfringens ATCC 13124	ABG85036.1	Q0TTW4		3
Desal_3470		Desulfovibrio salexigens DSM 2638	ACS81518.1	C6BSR2		3
MXAN_2688 (probable fragment)		Myxococcus xanthus DK 1622	ABF91274.1	Q1D8W8		3
Psed_1851		Pseudonocardia dioxanivorans CB1190	AEA24085.1			3
Ping_0433		Psychromonas ingrahamii 37	ABM02293.1	A1SS28		3
ROP_58040		Rhodococcus opacus B4	BAH54051.1	C1AY56		3
STAUR_3425 (fragment)		Stigmatella aurantiaca DW4/3-1	ADO71215.1	E3G012		3
SCO0388		Streptomyces coelicolor A3(2)	CAB58329.1			3
SHJG_7000		Streptomyces hygroscopicus subsp. jinggangensis 5008	AEY92267.1			3
SCAB_23411		Streptomyces scabiei 87.22	CBG69454.1	C9YYZ9		3
SVEN_7193		Streptomyces venezuelae ATCC 10712	CCA60479.1			3
Strvi_5605		Streptomyces violaceusniger Tu 4113	AEM85122.1			3