Polysaccharide Lyase Family 12

Activities in Family	Heparin lyase / heparin lyase I (EC 4.2.2.7); Heparin-sulfate lyase / heparin lyase III (EC 4.2.2.8);
Mechanism	b-elimination
3D Structure Status	( α / α ) ₅ toroid + anti-parallel β-sheet
Statistics	GenBank accession (2059); Uniprot accession (5); PDB accession (5); 3D entries (3); cryst (0)

Summary

Download PL12 (2030) Taxonomic display Structure (3) Characterized (4)

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Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
RW64_20745 (fragment)		Geobacter sulfurreducens AM-1	AJY72002.1			3
F1728_13110		Gimesia benthica E7	QGQ23558.1
X907_1848		Glycocaulis alkaliphilus 6B-8	AZU04375.1
NQ540_05790 (fragment)		Granulicatella adiacens ATCC 49175	UWP37439.1
N8I82_05760 (fragment)		Granulicatella adiacens KHUD_009	UXY40722.1
HBHAL_4425		Halobacillus halophilus DSM 2266	CCG46765.1
CEH05_16885		Halobacillus halophilus HL2HP6	ASF40738.1
LC065_07985		Halobacillus litoralis SaN21-8	WLR49089.1
MUN89_18820		Halobacillus salinarum SSBR10-3	UOQ43900.1
QAO71_09635		Halopseudomonas sp. SMJS2	WGK60361.1
HIF96_07585		Helcococcus kunzii H10	QZO76138.1
GUI37_08080		Helcococcus kunzii H13	QUY65480.1
EQF90_007650 (fragment)		Helcococcus ovis KG-36	WNZ01133.1			1
NQ487_21200 (fragment)		Hungatella hathewayi DSM 13479	UWO83377.1
NQ487_00785 (fragment)		Hungatella hathewayi DSM 13479	UWO85490.1
NNO_0443 (fragment)		Hydrogenimonas sp. (isolate MAG)	BBG65146.1
FRZ61_03370		Hypericibacter adhaerens R5959	QEX20420.1			3
FRZ44_03080		Hypericibacter terrae R5913	QEX15028.1			3
HC251_07825 (fragment)		Iamia sp. SCSIO 61187	QYG92357.1
P9875_25335		Janthinobacterium rivuli DEMB2	WFR78980.1
YQ44_03335		Janthinobacterium sp. 1_2014MBL_MicDiv	APA67015.1
OPV09_08520		Janthinobacterium sp. TB1-E2	WWO48136.1			3
EJN90_13650		Jeotgalibaca ciconiae H21T32	AZP05592.1			1
LZ578_01760		Jeotgalibaca sp. MA1X17-3	UJF15897.1			1
Q73A0000_08490		Kaistella flava 7-3A	QOW10400.1
RBB56_15310		Kineothrix sp. MB12-C1	WMC92201.1			1
RGQ21_03720		Kitasatospora aureofaciens Tu117	BET45390.1			3
O1G21_06095		Kitasatospora sp. HUAS 3-15	WBP85465.1			3
GXN75_05000		Kroppenstedtia eburnea DSM 45196	QKI81408.1
Q4V64_05995		Kutzneria buriramensis DSM 45791	WKX16035.1			3
ALGA_3298		Labilibaculum antarcticum SPP2	BAX81598.1
QJR73_04800		Lachnoanaerobaculum gingivalis SHL-20230108WGSARO1-L360107582	WHE88324.1			1
Cphy_3022		Lachnoclostridium phytofermentans ISDg	ABX43379.1			1
A4V08_28710		Lachnoclostridium sp. YL32	ANU49219.1			1
A4V08_05675		Lachnoclostridium sp. YL32	ANU50362.1			1
CE91St56_14920		Lachnospiraceae bacterium CE91-St56	BDF44369.1
CE91St56_37880 (fragment)		Lachnospiraceae bacterium CE91-St56	BDF46665.1
CE91St56_53880		Lachnospiraceae bacterium CE91-St56	BDF48265.1			1
I6K70_17610		Lacrimispora saccharolytica FDAARGOS_1340	QRV19257.1			1
LCA12A_0353		Lacticaseibacillus casei 12A	EKP96219.1			1
LCBD_2878		Lacticaseibacillus casei BD-II	AEA58372.1			1
LCABL_28520		Lacticaseibacillus casei BL23	CAQ67902.1			1
KGS74_10610		Lacticaseibacillus casei FBL6	QVI36694.1			1
LC2W_2852		Lacticaseibacillus casei LC2W	AEA55181.1			1
BGL52_13200		Lacticaseibacillus casei LC5	ARY92661.1			1
RWA16_12970		Lacticaseibacillus casei LMG 24099	WNX27295.1			1
RWA15_12970		Lacticaseibacillus casei LMG 24102	WNX24523.1			1
LOCK919_2912 (fragment)		Lacticaseibacillus casei LOCK919	AGP69575.1			1
U2Q69_04035		Lacticaseibacillus casei M233-24W	WQG47941.1			1
KTT66_09825		Lacticaseibacillus casei N	QXG58486.1			1
LCAZH_2660		Lacticaseibacillus casei str. Zhang	ADK19848.1 ADK19848.2 ADK19848.2			1
BN194_28010		Lacticaseibacillus casei W56	CCK23748.1			1
OFW50_12545		Lacticaseibacillus chiayiensis AACE 3	UYN56279.1			1
KG086_12315		Lacticaseibacillus chiayiensis FBL7	QVI34538.1			1
LHUE2_002640		Lacticaseibacillus DSM 115424	WFB41776.1			1
LHUE1_000816		Lacticaseibacillus DSM 115425	WFB40044.1			1
NCY29_13670		Lacticaseibacillus paracasei 401	URW91180.1			1
LSEI_2662		Lacticaseibacillus paracasei ATCC 334	ABJ71381.1			1
FGZ69_07180		Lacticaseibacillus paracasei CBA3611	QDP36677.1			1
HLG73_13975		Lacticaseibacillus paracasei CLP-Y5	WCZ20378.1			1
MWH19_07585		Lacticaseibacillus paracasei GM-080	WHR49833.1			1
J9325_11890		Lacticaseibacillus paracasei HM1	QTX17880.1			1
U8C12_13775		Lacticaseibacillus paracasei HP-B1337	WRP02819.1			1
RF667_09890		Lacticaseibacillus paracasei KCKM 0245	WMX59444.1			1
AWC33_12705		Lacticaseibacillus paracasei KL1	ALX89977.1			1
KZR06_13620		Lacticaseibacillus paracasei L1	UWP76438.1			1
RWA18_12415		Lacticaseibacillus paracasei LMG 19719	WNX21831.1			1
DMC16_09065		Lacticaseibacillus paracasei Lpc10	AWR91269.1			1
SGY26_02005		Lacticaseibacillus paracasei M115-8W-2	WPP11921.1			1
AF91_13355		Lacticaseibacillus paracasei N1115	AHJ34083.1			1
HCJ88_12250		Lacticaseibacillus paracasei NFFJ04	QOP56483.1			1
OK107_00220		Lacticaseibacillus paracasei NG-LCU-NJ2	WBS99155.1			1
G5C68_08495		Lacticaseibacillus paracasei NSMJ15	QOP48319.1			1
NY1301_27500		Lacticaseibacillus paracasei NY1301	BEQ12509.1			1
T1M39_10425		Lacticaseibacillus paracasei S135-24W	WRM19354.1			1
MRE03_12350		Lacticaseibacillus paracasei SCB0563	UOG14932.1			1
NPC72_13700		Lacticaseibacillus paracasei SMN-LBK	UUD39266.1			1
EVE90_14625		Lacticaseibacillus paracasei SRCM103299	QBA75458.1			1
NUU02_13835		Lacticaseibacillus paracasei subsp. paracasei 01	UUY33079.1			1
L3C06_13505		Lacticaseibacillus paracasei subsp. paracasei 0562	UJS07587.1			1
LBPG_01252		Lacticaseibacillus paracasei subsp. paracasei 8700:2	EEQ65803.1			1
J5Y16_07535		Lacticaseibacillus paracasei subsp. paracasei GR0548	QXJ66786.1			1
LBPC_2632 (fragment)		Lacticaseibacillus paracasei subsp. paracasei JCM 8130	BAN72928.1			1
KFU60_08930		Lacticaseibacillus paracasei subsp. tolerans 2A	QUS97649.1			1
CYL78_14815		Lacticaseibacillus paracasei subsp. tolerans 7112-2	AZQ00009.1			1
LacP0245_08910		Lacticaseibacillus paracasei subsp. tolerans MGB0245	QPC12347.1			1
LacP0625_14355		Lacticaseibacillus paracasei subsp. tolerans MGB0625	QPC21755.1			1
LacP0734_11000		Lacticaseibacillus paracasei subsp. tolerans MGB0734	QPC18172.1			1
JK381_13640		Lacticaseibacillus paracasei subsp. tolerans S-NA5	QQX67888.1			1
JK384_13650		Lacticaseibacillus paracasei subsp. tolerans S-NB	QQX70741.1			1
I3F57_13950		Lacticaseibacillus paracasei subsp. tolerans ZY-1	QPI87991.1			1
BKQ19_12750		Lacticaseibacillus paracasei TK1501	ASU13576.1			1
LT340_13790		Lacticaseibacillus paracasei VHProbi F22	UMO94466.1			1
SHN02_13315		Lacticaseibacillus paracasei YE01	WPH54615.1			1
CFM84_11540		Lacticaseibacillus paracasei ZFM54	AYG23688.1			1
A0F16_11365		Lacticaseibacillus rhamnosus ASCC 290	AMQ04012.1			1
LRHK_2791 (fragment)		Lacticaseibacillus rhamnosus ATCC 8530	AER65509.1			1
JGE02_12695		Lacticaseibacillus rhamnosus B6	QQN31423.1			1
GMB04_13280		Lacticaseibacillus rhamnosus BIO5326	QGQ35749.1			1
K6087_08535		Lacticaseibacillus rhamnosus CAU 1365	UAM88643.1			1
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