Polysaccharide Lyase Family 12

Activities in Familyheparin-sulfate lyase (EC 4.2.2.8); heparin lyase / heparin lyase I (EC 4.2.2.7)
Mechanism b-elimination
3D Structure Status( a / a ) 5 toroid + anti-parallel β-sheet
Statistics GenBank accession (1149); Uniprot accession (80); PDB accession (5); 3D entries (3); cryst (0)
All (1116) Bacteria (1116) Structure (3) Characterized (4)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 12 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 AM1_1276   Acaryochloris marina MBIC11017 ABW26313.1 B0C573  
 ADCFC_16920 (fragment)   Adlercreutzia sp. 8CFCBH1 BCA89073.1    
 AP3564_03725   Aeribacillus pallidus KCTC3564 ASS92252.1    
 PYTT_0036   Akkermansia glycaniphila SEH69485.1     2
 EGY22_02750   Alcaligenes faecalis FDAARGOS_491 AYZ90456.1    
 GWQ43_18005 (fragment)   Alcaligenes faecalis MUB14 QHS37835.1    
 APS56_13705   Algibacter alginicilyticus HZ22 ALJ06119.1    
 APS56_15080   Algibacter alginicilyticus HZ22 ALJ06861.1    
 AL1_01210   Alistipes shahii WAL 8301 CBK62838.1 D4IIS6   2
 AL1_01260   Alistipes shahii WAL 8301 CBK62842.1 D4IIT0   2
 AL1_01270 (fragment)   Alistipes shahii WAL 8301 CBK62843.1 D4IIT1   2
 AL1_01890 (fragment)   Alistipes shahii WAL 8301 CBK62900.1 D4IIY8   2
 Ami3637_01810   Aminipila sp. CBA3637 QHI71299.1    
 AJAP_36840   Amycolatopsis japonica MG417-CF17 AIG80166.1     3
 SAMN04489733_5383   Amycolatopsis keratiniphila FH 1893 SDU51998.1     3
 BB31_14520   Amycolatopsis lurida NRRL 2430 AJK54519.1     3
 B737_0552   Amycolatopsis mediterranei RB AGT81216.1     3
 RAM_02835   Amycolatopsis mediterranei S699 AEK39059.1
AFO74087.1
    3
 AMED_0553   Amycolatopsis mediterranei U32 ADJ42373.1 D8HZ18   3
 AMETH_0536   Amycolatopsis methanolica 239 AIJ20628.1     3
 AMETH_6136   Amycolatopsis methanolica 239 AIJ26228.1    
 SD37_38410   Amycolatopsis orientalis B-37 ANN20886.1     3
 AORI_0560   Amycolatopsis orientalis HCCB10007 AGM03149.1     3
 BKN51_37005   Amycolatopsis sp. BJA-103 AUI63200.1     3
 YIM_21515   Amycolatopsis sp. YIM 10 QFU89482.1     3
 ANT_24620   Anaerolinea thermophila UNI-1 BAJ64488.1     3
 BEQ56_11510   Anaerolineaceae bacterium oral taxon 439 W11661 AOH44043.1    
 A2cp1_1481   Anaeromyxobacter dehalogenans 2CP-1 ACL64825.1 B8JHC3   3
 Adeh_2473   Anaeromyxobacter dehalogenans 2CP-C ABC82243.1 Q2IKR1   3
 AnaeK_1385   Anaeromyxobacter sp. K ACG72616.1 B4UJ55   3
 D1818_13010   Aquimarina sp. BL5 AXT51715.1    
 AA314_07058   Archangium gephyra DSM 2261 AKJ05432.1    
 AMRN_0894   Arcobacter marinus JCM 15502 AXX86646.1    
 AREALGSMS7_03768 (HepC)   Arenibacter algicola SMS7 ASO07178.1    
 MyAD_23930   Arthrobacter sp. SLBN-53 str. NRRL B-3805 AMO07696.1    
 FOC92_14660   Bacillus cereus FDAARGOS_798 QKH13154.1    
 FOC93_22855   Bacillus cereus FDAARGOS_799 QKH08761.1    
 BA204_25570   Bacillus cereus K8 ASJ51297.1    
 CEQ83_05715   Bacillus megaterium QFY72029.1    
 HFZ78_11140 (fragment)   Bacillus megaterium S2 QIZ10902.1     1
 GD442_25710 (fragment)   Bacillus sp. A260 QGY38134.1    
 DPQ31_26670   Bacillus sp. COPE52 AXK21098.1    
 A6J74_18160   Bacillus sp. FDAARGOS_235 ARC30630.1    
 FSZ17_19085   Bacillus sp. FJAT-25496 QED49189.1    
 BHV55_26245   Bacillus sp. RZ2MS9 QIZ45027.1    
 NF53_5189   Bacillus thuringiensis serovar indiana HD521 AKR38266.1    
 FHG85_08140 (fragment)   Bacteroidales bacterium 38-H QKG80231.1    
 FHG85_03995   Bacteroidales bacterium 38-H QKG79462.1    
 A4V03_04745   Bacteroides caecimuris I48 ANU56966.1     2
 A4V03_04720   Bacteroides caecimuris I48 ANU56961.1     2
 BcellWH2_01704 (HepC)   Bacteroides cellulosilyticus WH2 ALJ58957.1     2
 EL88_09435   Bacteroides dorei isolate HS1_L1_B_010 AII63382.1    
 E0L14_07985   Bacteroides fragilis CCUG4856T QCT77341.1    
 BF0747   Bacteroides fragilis NCTC 9343 CAH06493.1 Q5LH92  
 Bache_1616   Bacteroides helcogenes P 36-108 ADV43619.1     2
 Bache_2449   Bacteroides helcogenes P 36-108 ADV44415.1    
 C3V43_00350   Bacteroides heparinolyticus F0111 AVM56400.1     2
 DXK01_000620   Bacteroides intestinalis APC919/174 QDO67526.1     2
 DYI28_27195   Bacteroides ovatus 3725 D1 iv QDM12096.1     2
 DYI28_27170   Bacteroides ovatus 3725 D1 iv QDM12091.1     2
 DYI28_01320   Bacteroides ovatus 3725 D1 iv QDM12489.1    
 Bovatus_01804 (Hepc_1)   Bacteroides ovatus ATCC 8483 ALJ46444.1     2
 Bovatus_04868 (Hepc_3)   Bacteroides ovatus ATCC 8483 ALJ49456.1     2
 Bovatus_04863 (Hepc_2)   Bacteroides ovatus ATCC 8483 ALJ49451.1     2
 FOC41_24860   Bacteroides ovatus FDAARGOS_733 QGT73981.1     2
 FOC41_24885   Bacteroides ovatus FDAARGOS_733 QGT73986.1     2
 BACOV975_02669   Bacteroides ovatus V975 SCV08875.1     2
 BACOV975_02674   Bacteroides ovatus V975 SCV08880.1     2
 BACOV975_04594   Bacteroides ovatus V975 SCV10800.1     2
 EYA81_01750   Bacteroides sp. A1C1 QBJ17188.1    
 BacF7301_13570   Bacteroides sp. CBA7301 QIU95106.1     2
 BacF7301_13600   Bacteroides sp. CBA7301 QIU95112.1     2
 BacF7301_07560   Bacteroides sp. CBA7301 QIU94010.1    
 BacF7301_13595   Bacteroides sp. CBA7301 QIU95111.1     2
 heparinase III / heparin lyase III (HepIII) 4.2.2.8 Bacteroides stercoris HJ-15 ACT66689.1 C7EXL6   2
 Btheta7330_03335 (Hepc_2)   Bacteroides thetaiotaomicron 7330 ALJ42868.1     2
 Btheta7330_03330 (Hepc_1)   Bacteroides thetaiotaomicron 7330 ALJ42863.1     2
 BatF92_12260   Bacteroides thetaiotaomicron F9-2 BCA49284.1     2
 BatF92_12310 (HepC)   Bacteroides thetaiotaomicron F9-2 BCA49289.1     2
 lyase cleaving heparin, heparan sulfate and desulfated heparin (HepIII; BT4662) 4.2.2.7
4.2.2.8
Bacteroides thetaiotaomicron VPI-5482 AAO79767.1
NP_813573.1
Q89YR9 4FNV[A] 2
 lyase cleaving heparin, heparan sulfate and desulfated heparin (Hep III; BT4657;BT_4657) 4.2.2.7
4.2.2.8
Bacteroides thetaiotaomicron VPI-5482 AAO79762.1
NP_813568.1
Q89YS4 5JMD[A]
5JMF[A]
2
 Bun01g_31100 (fragment)   Bacteroides uniformis NBRC 113350 BBK88740.1    
 FKZ68_12490   Bacteroides xylanisolvens H207 QDH54993.1     2
 FKZ68_12515   Bacteroides xylanisolvens H207 QDH54998.1     2
 BXY_37640   Bacteroides xylanisolvens XB1A CBK68723.1 D6D2S1   2
 BXY_37690   Bacteroides xylanisolvens XB1A CBK68728.1 D6D2S6   2
 CGC63_14860   Blautia hansenii DSM 20583 ASM70659.1     1
 FRD00_13215   Bradymonadales bacterium YN101 QED32896.1    
 FIV42_13220   Bradymonas sp. YN101 QDG51675.1    
 CIT40_06150   Bradyrhizobium amphicarpaeae 2 39S1MB AWL99652.1     3
 Bdiaspc4_33215   Bradyrhizobium diazoefficiens 110spc4 QBP25054.1     3
 HAU57_41955   Bradyrhizobium diazoefficiens 172S4 QIO97641.1     3
 BE61_69020   Bradyrhizobium elkanii USDA 61 BBC01441.1     3
 BKD09_RS19565   Bradyrhizobium japonicum J5 APG10528.1    
 BJS_00411   Bradyrhizobium japonicum SEMIA 5079 AHY53038.1    
 BN2626_G22_3334   Bradyrhizobium sp. CUU16918.1    
 G6P99_45615   Bradyrhizobium sp. 6(2017) 1S3 QIG98761.1     3
 BRADO7043   Bradyrhizobium sp. ORS 278 CAL80627.1 A4Z3A1   3
 CWS35_18870   Bradyrhizobium sp. SK17 AUC96083.1     3
 Pan97_38930 (Hepc_2)   Bremerella volcania Pan97 QDU76836.1    
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