Polysaccharide Lyase Family 12

Activities in Familyheparin-sulfate lyase (EC 4.2.2.8)
Statistics GenBank accession (537); Uniprot accession (81); PDB accession (5); 3D entries (3); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 AM1_1276   Acaryochloris marina MBIC11017 ABW26313.1 B0C573  
 AP3564_03725   Aeribacillus pallidus KCTC3564 ASS92252.1    
 PYTT_0036   Akkermansia glycaniphila SEH69485.1     2
 APS56_13705   Algibacter alginicilyticus HZ22 ALJ06119.1    
 APS56_15080   Algibacter alginicilyticus HZ22 ALJ06861.1    
 AL1_01210   Alistipes shahii WAL 8301 CBK62838.1 D4IIS6   2
 AL1_01260   Alistipes shahii WAL 8301 CBK62842.1 D4IIT0   2
 AL1_01270 (fragment)   Alistipes shahii WAL 8301 CBK62843.1 D4IIT1   2
 AL1_01890 (fragment)   Alistipes shahii WAL 8301 CBK62900.1 D4IIY8   2
 AJAP_36840   Amycolatopsis japonica MG417-CF17 AIG80166.1     3
 SAMN04489733_5383   Amycolatopsis keratiniphila FH 1893 SDU51998.1     3
 BB31_14520   Amycolatopsis lurida NRRL 2430 AJK54519.1     3
 B737_0552   Amycolatopsis mediterranei RB AGT81216.1     3
 RAM_02835   Amycolatopsis mediterranei S699 AEK39059.1
AFO74087.1
    3
 AMED_0553   Amycolatopsis mediterranei U32 ADJ42373.1 D8HZ18   3
 AMETH_0536   Amycolatopsis methanolica 239 AIJ20628.1     3
 AMETH_6136   Amycolatopsis methanolica 239 AIJ26228.1    
 SD37_38410   Amycolatopsis orientalis B-37 ANN20886.1     3
 AORI_0560   Amycolatopsis orientalis HCCB10007 AGM03149.1     3
 ANT_24620   Anaerolinea thermophila UNI-1 BAJ64488.1     3
 BEQ56_11510   Anaerolineaceae bacterium oral taxon 439 W11661 AOH44043.1    
 A2cp1_1481   Anaeromyxobacter dehalogenans 2CP-1 ACL64825.1 B8JHC3   3
 Adeh_2473   Anaeromyxobacter dehalogenans 2CP-C ABC82243.1 Q2IKR1   3
 AnaeK_1385   Anaeromyxobacter sp. K ACG72616.1 B4UJ55   3
 AA314_07058   Archangium gephyra DSM 2261 AKJ05432.1    
 AREALGSMS7_03768 (HepC)   Arenibacter algicola SMS7 ASO07178.1    
 BA204_25570   Bacillus cereus K8 ASJ51297.1    
 A6J74_18160   Bacillus sp. FDAARGOS_235 ARC30630.1    
 NF53_5189   Bacillus thuringiensis serovar indiana HD521 AKR38266.1    
 A4V03_04745   Bacteroides caecimuris I48 ANU56966.1     2
 A4V03_04720   Bacteroides caecimuris I48 ANU56961.1     2
 BcellWH2_01704 (HepC)   Bacteroides cellulosilyticus WH2 ALJ58957.1     2
 EL88_09435   Bacteroides dorei isolate HS1_L1_B_010 AII63382.1    
 BF0747   Bacteroides fragilis NCTC 9343 CAH06493.1 Q5LH92  
 Bache_1616   Bacteroides helcogenes P 36-108 ADV43619.1     2
 Bache_2449   Bacteroides helcogenes P 36-108 ADV44415.1    
 Bovatus_01804 (Hepc_1)   Bacteroides ovatus ATCC 8483 ALJ46444.1     2
 Bovatus_04868 (Hepc_3)   Bacteroides ovatus ATCC 8483 ALJ49456.1     2
 Bovatus_04863 (Hepc_2)   Bacteroides ovatus ATCC 8483 ALJ49451.1     2
 BACOV975_02669   Bacteroides ovatus V975 SCV08875.1     2
 BACOV975_02674   Bacteroides ovatus V975 SCV08880.1     2
 BACOV975_04594   Bacteroides ovatus V975 SCV10800.1     2
 heparinase III / heparin lyase III (HepIII) 4.2.2.8 Bacteroides stercoris HJ-15 ACT66689.1 C7EXL6   2
 Btheta7330_03335 (Hepc_2)   Bacteroides thetaiotaomicron 7330 ALJ42868.1     2
 Btheta7330_03330 (Hepc_1)   Bacteroides thetaiotaomicron 7330 ALJ42863.1     2
 heparinase III (BT4662) 4.2.2.8 Bacteroides thetaiotaomicron VPI-5482 AAO79767.1
NP_813573.1
Q89YR9 4FNV[A] 2
 heparinase III (BT4657;BT_4657)   Bacteroides thetaiotaomicron VPI-5482 AAO79762.1
NP_813568.1
Q89YS4 5JMD[A]
5JMF[A]
2
 BXY_37640   Bacteroides xylanisolvens XB1A CBK68723.1 D6D2S1   2
 BXY_37690   Bacteroides xylanisolvens XB1A CBK68728.1 D6D2S6   2
 CGC63_14860   Blautia hansenii DSM 20583 ASM70659.1     1
 BKD09_RS19565   Bradyrhizobium japonicum J5 APG10528.1    
 BJS_00411   Bradyrhizobium japonicum SEMIA 5079 AHY53038.1    
 BN2626_G22_3334   Bradyrhizobium sp. CUU16918.1    
 BRADO7043   Bradyrhizobium sp. ORS 278 CAL80627.1 A4Z3A1   3
 Cabys_1106   Caldithrix abyssi DSM 13497 LF13 APF17855.1    
 Cabys_1025   Caldithrix abyssi DSM 13497 LF13 APF17776.1    
 NIES4071_29020   Calothrix sp. NIES-4071 BAZ11077.1    
 NIES4105_28960   Calothrix sp. NIES-4105 BAZ57223.1    
 Cal6303_2160   Calothrix sp. PCC 6303 AFZ01181.1    
 CAP2UW1_0857 (fragment)   Candidatus Accumulibacter phosphatis clade IIA str. UW-1 ACV34195.1 C7RNQ9   3
 HS1_001643   Candidatus Desulfofervidus auxilii HS1 AMM41437.1    
 Acid345_3793   Candidatus Koribacter versatilis Ellin345 ABF42793.1 Q1IK07   3
 Acid_0038   Candidatus Solibacter usitatus Ellin6076 ABJ81054.1 Q02D12  
 Acid_7470   Candidatus Solibacter usitatus Ellin6076 ABJ88378.1 Q01PP2   3
 Celal_0441   Cellulophaga algicola DSM 14237 ADV47782.1    
 M666_19565   Cellulophaga baltica 18 AIZ43554.1    
 M667_19650   Cellulophaga baltica NN016038 AIY15190.1    
 Ctha_1213   Chloroherpeton thalassium ATCC 35110 ACF13677.1 B3QYY4   3
 Ctha_2022   Chloroherpeton thalassium ATCC 35110 ACF14474.1 B3QUX3   3
 CMC5_017220   Chondromyces crocatus Cm c5 AKT37581.1    
 CACET_c01410   Clostridium aceticum DSM 1496 AKL93659.1    
 NPD11_524   Clostridium baratii CDC51267 AQM59855.1    
 NPD11_2454   Clostridium baratii CDC51267 AQM60684.1    
 U729_2949   Clostridium baratii str. Sullivan AIY82262.1     1
 U729_2508   Clostridium baratii str. Sullivan AIY82803.1    
 LF65_01179   Clostridium beijerinckii NCIMB 14988 AJG97793.2    
 CGC65_09940   [Clostridium] bolteae ATCC BAA-613 ASN94973.1     1
 CGC65_10330   [Clostridium] bolteae ATCC BAA-613 ASN95045.1     1
 CbC4_1804+CbC4_1805   Clostridium botulinum BKT015925 AEB76478.1
AEB76479.1
    1
 T258_1442   Clostridium botulinum Prevot_594 AJD30348.1    
 BTM20_11280   Clostridium chauvoei 12S0467 ATD55782.1     1
 BTM21_01740   Clostridium chauvoei DSM 7528 ATD56543.1     1
 CCH01_21450   Clostridium chauvoei JF4335 SLK21590.1     1
 CPF_0406   Clostridium perfringens ATCC 13124 ABG82423.1 Q0TU27   1
 CPF_0471   Clostridium perfringens ATCC 13124 ABG85036.1 Q0TTW4  
 JFP55_02405   Clostridium perfringens JP55 AMN31821.1     1
 CMR01_13065   Clostridium perfringens LLY_N11 ATD49680.1     1
 CPR_0402   Clostridium perfringens SM101 ABG87833.1 Q0SVW9   1
 CPR_0460   Clostridium perfringens SM101 ABG85999.1 Q0SVR1  
 Closa_4172   [Clostridium] saccharolyticum WM1 ADL06674.1 D9R2Q0   1
 SAMN02745906_3894   [Clostridium] sphenoides JCM 1415 ATCC 19403 SEU00790.1     1
 SAMN02745906_4733   [Clostridium] sphenoides JCM 1415 ATCC 19403 SEU07992.1     1
 CLSPOx_13800   Clostridium sporogenes DSM 795 AKJ90646.1    
 CLSPO_c27570   Clostridium sporogenes NCIMB 10696 AKC63477.1    
 COCOR_05352   Corallococcus coralloides DSM 2259 AFE06326.1    
 CA2015_0636   Cyclobacterium amurskyense KCTC 12363 AKP50101.1    
 CA2015_4553   Cyclobacterium amurskyense KCTC 12363 AKP53889.1    
 Cycma_0757   Cyclobacterium marinum DSM 745 AEL24531.1    
 Cycma_4737   Cyclobacterium marinum DSM 745 AEL28422.1    
 CYFUS_003046   Cystobacter fuscus DSM 52655 ATB37621.1    
 SAMN06298216_1264   Cytophagales bacterium TFI 002 SOE20783.1    
 SAMN06298216_4073   Cytophagales bacterium TFI 002 SOE23689.1     2
 Desac_1339   Desulfobacca acetoxidans DSM 11109 AEB09196.1    
 Desac_2205   Desulfobacca acetoxidans DSM 11109 AEB10034.1    
 TOL2_C36580   Desulfobacula toluolica Tol2 CCK81814.1     3
 UWK_01795   Desulfocapsa sulfexigens DSM 10523 AGF78353.1    
 Dmul_32380   Desulfococcus multivorans DSM 2059 AOY60008.1
AQV03093.2
   
 Desti_4537   Desulfomonile tiedjei DSM 6799 AFM27165.1    
 DESAM_22567   Desulfovibrio hydrothermalis AM13 = DSM 14728 CCO24834.1     3
 DESAM_22567   Desulfovibrio hydrothermalis sp nov AM13 CCO00827.1     3
 Desal_3470   Desulfovibrio salexigens DSM 2638 ACS81518.1 C6BSR2   3
 I597_0904 (HepC)   Dokdonia donghaensis DSW-1 ANH59830.1    
 Krodi_0316   Dokdonia sp. 4H-3-7-5 AEE18302.1    
 MED134_10675   Dokdonia sp. MED134 EAQ38155.1    
 MED134_05964   Dokdonia sp. MED134 EAQ40276.1    
 CK496_10295   Enterococcus thailandicus a523 ASZ08277.1    
 A2I91_03205   Erysipelothrix rhusiopathiae GXBY-1 AMS10800.1     1
 ERH_1218   Erysipelothrix rhusiopathiae str. Fujisawa BAK32272.1     1
 K210_04235 (fragment)   Erysipelothrix rhusiopathiae SY1027 AGN24452.1     1
 K210_04240 (fragment)   Erysipelothrix rhusiopathiae SY1027 AGN24453.1     1
 BC346_00900   Erysipelothrix rhusiopathiae WH13013 AOO66928.1     1
 A6C57_20710   Fibrella sp. ES10-3-2-2 ARK12560.1    
 UJ101_00293 (HepC)   Flavobacteriaceae bacterium UJ101 APD05845.1    
 FBFL15_1578   Flavobacterium branchiophilum FL-15 CCB69642.1    
 ALW18_13895   Flavobacterium psychrophilum Z1 AOE54419.1    
 AMR72_13905   Flavobacterium psychrophilum Z2 ALM50795.1    
 BN863_24500   Formosa agariphila KMM 3901 CDF80162.1    
 CBG50_12830 (fragment)   Fusobacterium nucleatum subsp. polymorphum KCOM 1260 (=ChDC F218) ASC04272.1    
 GM18_1586   Geobacter sp. M18 ADW13052.1    
 RW64_20745 (fragment)   Geobacter sulfurreducens AM-1 AJY72002.1    
 GJA_3987   Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628 CDG84598.1     3
 BZG29_08180   Janthinobacterium sp. LM6 AQR71833.1    
 mma_2266   Janthinobacterium sp. Marseille ABR91662.1 A6T0A9  
 JMA_29400   Jeotgalibacillus malaysiensis D5 AJD92257.1    
 L21SP4_02293   Kiritimatiella glycovorans L21-Fru-AB AKJ65520.1    
 Cphy_3022   Lachnoclostridium phytofermentans ISDg ABX43379.1 A9KQ67   1
 A4V08_28710   Lachnoclostridium sp. YL32 ANU49219.1     1
 A4V08_05675   Lachnoclostridium sp. YL32 ANU50362.1     1
 BWR22_00765   Lacinutrix venerupis DOK2-8 APX98895.1    
 LCA12A_0353   Lactobacillus casei 12A EKP96219.1     1
 LCBD_2878   Lactobacillus casei BD-II AEA58372.1     1
 LCABL_28520   Lactobacillus casei BL23 CAQ67902.1 B3WB33   1
 LC2W_2852   Lactobacillus casei LC2W AEA55181.1     1
 BGL52_13200   Lactobacillus casei LC5 ARY92661.1     1
 LOCK919_2912 (fragment)   Lactobacillus casei LOCK919 AGP69575.1     1
 LCAZH_2660   Lactobacillus casei str. Zhang ADK19848.1
ADK19848.2
ADK19848.2
D8GDH1   1
 BN194_28010   Lactobacillus casei W56 CCK23748.1     1
 LSEI_2662   Lactobacillus paracasei ATCC 334 ABJ71381.1 Q034J1   1
 AWC33_12705   Lactobacillus paracasei KL1 ALX89977.1     1
 AF91_13355   Lactobacillus paracasei N1115 AHJ34083.1     1
 LBPG_01252   Lactobacillus paracasei subsp. paracasei 8700:2 EEQ65803.1     1
 LBPC_2632 (fragment)   Lactobacillus paracasei subsp. paracasei JCM 8130 BAN72928.1     1
 BKQ19_12750   Lactobacillus paracasei TK1501 ASU13576.1     1
 A0F16_11365   Lactobacillus rhamnosus ASCC 290 AMQ04012.1     1
 LRHK_2791 (fragment)   Lactobacillus rhamnosus ATCC 8530 AER65509.1     1
 LC705_02682   Lactobacillus rhamnosus Lc 705 CAR91521.1 C7TMT7   1
 LOCK900_2681 (fragment)   Lactobacillus rhamnosus LOCK900 AGP72458.1     1
 LOCK908_2762 (fragment)   Lactobacillus rhamnosus LOCK908 AGP75368.1     1
 BGK71_12695   Lactobacillus rhamnosus LR5 ASX18218.1     1
 BVH57_01970   Lactobacillus rhamnosus Pen ARD31273.1     1
 MCCS_08940 (HepC)   Macrococcus canis KM45013 ARQ06541.1    
 YQ22_05090   Maribacter sp. 1_2014MBL_MicDiv APA63739.1    
 SAMN05192545_0156   Maribacter sp. MAR_2009_60 SDR79647.1    
 ALGA_3298   Marinifilaceae bacterium SPP2 BAX81598.1    
 ACZ75_11685   Massilia sp. NR 4-1 AKU22028.1     3
 AM586_08675   Massilia sp. WG5 ALK99447.1    
 MROS_1363   Melioribacter roseus P3M-2 AFN74600.1    
 MEBOL_000532   Melittangium boletus DSM 14713 ATB27097.1    
 sS8_5648   Methylocaldum marinum S8 BBA37565.1    
 JT25_023470   Methylomonas denitrificans FJG1 AMK79409.1    
 JT25_023465   Methylomonas denitrificans FJG1 AMK79408.1    
 BJP36_34925   Moorea producens JHB AOY84351.1    
 MVIS_1950   Moritella viscosa CED59916.1     3
 D174_24390   Mycobacterium neoaurum VKM Ac-1815D AHC28087.1    
 AB431_05225   Mycobacterium sp. EPa45 AKK30259.1    
 MyAD_23930   Mycobacterium sp. NRRL B-3805 AMO07696.1    
 MFUL124B02_16870   Myxococcus fulvus 124B02 AKF80976.1    
 LILAB_21135   Myxococcus fulvus HW-1 AEI66127.1    
 A176_004342   Myxococcus hansupus AKQ67430.1    
 MYMAC_002651   Myxococcus macrosporus DSM 14697 ATB47044.1    
 MYSTI_03090   Myxococcus stipitatus DSM 14675 AGC44404.1    
 MXAN_2688 (probable fragment)   Myxococcus xanthus DK 1622 ABF91274.1 Q1D8W8   3
 Nther_2527   Natranaerobius thermophilus JW/NM-WN-LF ACB86087.1 B2A193  
 A8C56_05370   Niabella ginsenosidivorans BS26 ANH80495.1     2
 NIASO_15680   Niabella soli DSM 19437 AHF16202.1     2
 NAL212_0401   Nitrosomonas sp. AL212 ADZ25346.1    
 ATY38_03915   Nitrosomonas ureae Nm10 ALQ50457.1    
 SAMN06296273_1819   Nitrosomonas ureae Nm15 SNX60358.1    
 NIDE3009   Nitrospira defluvii CBK42705.1 D8PHG8  
 NITMOv2_4769   Nitrospira moscoviensis NSP M-1 ALA61138.1    
 NITMOv2_2635   Nitrospira moscoviensis NSP M-1 ALA59048.1    
 NITMOv2_2632   Nitrospira moscoviensis NSP M-1 ALA59045.1    
 I601_0107   Nocardioides dokdonensis FR1436 ANH36561.1     3
 BST91_03995   Nonlabens sediminis NBRC 100970 ARN70868.1    
 BST97_07005   Nonlabens spongiae JCM 13191 ARN77766.1    
 BST96_08175   Oceanicoccus sagamiensis NBRC 107125 ARN74101.1    
 OPIT5_08655   Opitutaceae bacterium TAV5 AHF90266.1    
 OPIT5_12400   Opitutaceae bacterium TAV5 AHF90891.1    
 OPIT5_13765   Opitutaceae bacterium TAV5 AHF91117.1    
 OPIT5_22720   Opitutaceae bacterium TAV5 AHF92618.1    
 OPIT5_28860 (fragment)   Opitutaceae bacterium TAV5 AHF93608.1    
 AEV32388.1 (fragment)   Owenweeksia hongkongensis DSM 17368 AEV32388.1    
 PBOR_05665   Paenibacillus borealis DSM 13188 AIQ56480.1    
 PGRAT_20055   Paenibacillus graminis DSM 15220 AIQ69665.1    
 B4V02_07215   Paenibacillus kribbensis AM49 ASR46481.1    
 PODO_07795   Paenibacillus odorifer DSM 15391 AIQ73161.1    
 PRIO_4321   Paenibacillus riograndensis SBR5 CQR56723.1    
 BBD42_12500   Paenibacillus sp. BIHB4019 ANY67193.1    
 H70357_22745 (fragment)   Paenibacillus sp. FSL H7-0357 AIQ19213.1    
 H70737_07560   Paenibacillus sp. FSL H7-0737 AIQ22723.1    
 H70737_02255   Paenibacillus sp. FSL H7-0737 AIQ21779.1    
 P40081_05955   Paenibacillus sp. FSL P4-0081 AIQ27783.1    
 R50345_07845   Paenibacillus sp. FSL R5-0345 AIQ34533.1    
 R50345_02160   Paenibacillus sp. FSL R5-0345 AIQ33561.1    
 R50912_05265   Paenibacillus sp. FSL R5-0912 AIQ39508.1    
 CIC07_07880   Paenibacillus sp. RUD330 ASS66067.1     1
 GYMC10_2636   Paenibacillus sp. Y412MC10 ACX64907.1 D3EB18   1
 SY83_13420   Paenibacillus swuensis DY6 ANE47095.1    
 HPL003_26980   Paenibacillus terrae HPL-003 AET62108.1    
 SAMN05661091_5259   Paenibacillus uliginis N3/975 SMF90844.1    
 BS614_13410   Paenibacillus xylanexedens PAMC 22703 APO44909.1    
 A4V11_00340   Pediococcus acidilactici ZPA017 AOW73537.1     1
 heparin-sulfate lyase / heparinase III (HepC;Phep_3797) 4.2.2.8 Pedobacter heparinus DSM 2366 ACU05988.1
AAB18278.1
ACH00306.1
ACK26501.1
C6XUY0
Q59289
4MMH[A]
4MMI[A]
2
 DCMF_06615   Peptococcaceae bacterium DCMF ATW28414.1    
 ING2E5A_2618 (Hepc3)   Petrimonas mucosa DSM 28695 SCM59414.1    
 ING2E5A_2617 (Hepc1)   Petrimonas mucosa DSM 28695 SCM59413.1    
 SMSP2_01416   Phycisphaerae bacterium SM-Chi-D1 AQQ71052.1     2
 VN12_06985 (HepC)   Pirellula sp. SH-Sr6A AMV31848.1    
 SAMN04487762_0860   Polaribacter sp. Hel1_33_78 SDT95246.1    
 BTO07_14690   Polaribacter sp. SA4-12 ARV16313.1    
 BAY61_02335   Prauserella marina DSM 45268 ASR34018.1     3
 Psed_1851   Pseudonocardia dioxanivorans CB1190 AEA24085.1     3
 Pedsa_1818   Pseudopedobacter saltans DSM 12145 ADY52373.1     2
 Pedsa_1814   Pseudopedobacter saltans DSM 12145 ADY52369.1     2
 Ping_0433   Psychromonas ingrahamii 37 ABM02293.1 A1SS28   3
 PCNPT3_01350   Psychromonas sp. CNPT3 AGH80212.1     3
 PCNPT3_05460   Psychromonas sp. CNPT3 AGH81034.1    
 PCNPT3_11740   Psychromonas sp. CNPT3 AGH82284.1    
 R1CP_10040 (fragment)   Rhodococcus opacus 1CP ANS26724.1    
 ROP_58040   Rhodococcus opacus B4 BAH54051.1 C1AY56  
 RHOM_04155   Roseburia hominis A2-183 AEN95953.1    
 Runsl_0203   Runella slithyformis DSM 19594 AEI46660.1    
 Spico_1386   Sphaerochaeta coccoides DSM 17374 AEC02590.1     1
 Spico_1734   Sphaerochaeta coccoides DSM 17374 AEC02932.1     1
 SpiBuddy_0862   Sphaerochaeta globosa str. Buddy ADY12689.1     1
 SpiGrapes_1796   Sphaerochaeta pleomorpha str. Grapes AEV29592.1    
 CA265_11335   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS40212.1     2
 CA265_11340   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS40213.1     2
 BJP26_13605 (fragment)   Sphingomonas melonis TY AOW24485.1    
 BJP26_14030 (fragment)   Sphingomonas melonis TY AOW24550.1    
 SCLARK_001261 (fragment)   Spiroplasma clarkii CN-5 ARU91803.1
ATX71169.1
   
 STAUR_3425 (fragment)   Stigmatella aurantiaca DW4/3-1 ADO71215.1 E3G012   3
 Smon_0124 (fragment)   Streptobacillus moniliformis DSM 12112 ACZ00617.1 D1AWE1  
 SA111_02042   Streptococcus agalactiae CZT40264.1     1
 BQ8897_BM110_01929   Streptococcus agalactiae SIW58389.1     1
 BSA_19160   Streptococcus agalactiae 09mas018883 CCW38682.1     1
 V193_08315   Streptococcus agalactiae 138P AHN31092.1     1
 DN94_08315   Streptococcus agalactiae 138spar AHX75639.1     1
 GBS222_1564   Streptococcus agalactiae 2-22 CCO75228.1     1
 SAG1897   Streptococcus agalactiae 2603V/R AAN00759.1
NP_688886.1
    1
 CHF17_01875   Streptococcus agalactiae 874391 ASZ02113.1     1
 SAK_1865 (fragment)   Streptococcus agalactiae A909 ABA45675.1    
 GT95_09460   Streptococcus agalactiae C001 ASI66832.1     1
 W903_1835   Streptococcus agalactiae CNCTC 10/84 AIX05500.1     1
 GBSCOH1_1691   Streptococcus agalactiae COH1 CDN67157.1     1
 BB161_10160 (fragment)   Streptococcus agalactiae CUGBS591 ASA80507.1     1
 CUGBS08_01836 (fragment)   Streptococcus agalactiae CU_GBS_08 AMQ15384.1     1
 CUGBS98_01772 (fragment)   Streptococcus agalactiae CU_GBS_98 AMQ17375.1     1
 A6J82_03545   Streptococcus agalactiae FDAARGOS_254 ARC44487.1     1
 A9256_09185 (fragment)   Streptococcus agalactiae FWL1402 ANR97815.1     1
 AOY37_09340   Streptococcus agalactiae GBS ST-1 ALP88308.1     1
 AV644_09105   Streptococcus agalactiae GBS-M002 APS25790.1     1
 DK41_09885   Streptococcus agalactiae GBS1-NY AIK72423.1     1
 DK42_10580   Streptococcus agalactiae GBS2-NM AIK74622.1     1
 DX05_09855   Streptococcus agalactiae GBS6 AIK76529.1     1
 GBS85147_1789   Streptococcus agalactiae GBS85147 AKI58210.1     1
 A964_1765 (fragment)   Streptococcus agalactiae GD201008-001 AFS46522.1     1
 GX026_08325   Streptococcus agalactiae GX026 AKU02392.1     1
 GX064_08960 (fragment)   Streptococcus agalactiae GX064 AKU00721.1     1
 SAH002_09450   Streptococcus agalactiae H002 AKU04349.1     1
 SAHN016_09040 (fragment)   Streptococcus agalactiae HN016 AKT96844.1     1
 MSA_19830   Streptococcus agalactiae ILRI005 CCW40838.1     1
 SAIL_19140   Streptococcus agalactiae ILRI112 CCW42925.1     1
 Gbs1885   Streptococcus agalactiae NEM316 CAD47544.1
NP_736319.1
    1
 EN72_09970   Streptococcus agalactiae NGBS061 AIF87397.1     1
 AMM49_09150   Streptococcus agalactiae NGBS128 AMD33059.1     1
 AMR84_09510   Streptococcus agalactiae NGBS357 AOF51792.1     1
 EN73_09055   Streptococcus agalactiae NGBS572 AIF89333.1     1
 BTH44_08385   Streptococcus agalactiae S13 APO42364.1     1
 A9J19_08295   Streptococcus agalactiae S25 ANI27936.1     1
 SaSA20_1552   Streptococcus agalactiae SA20-06 AFV72992.1     1
 B2G84_09560   Streptococcus agalactiae Sag158 AQY27100.1     1
 B1H24_10070 (fragment)   Streptococcus agalactiae Sag37 AQY25085.1     1
 AMD29_09345 (fragment)   Streptococcus agalactiae SG-M1 ALB16771.1     1
 BB194_09545 (fragment)   Streptococcus agalactiae SG-M158 ASA84618.1     1
 BB197_09545 (fragment)   Streptococcus agalactiae SG-M163 ASA82564.1     1
 BB164_10100   Streptococcus agalactiae SG-M25 ASA90855.1     1
 BB268_09545 (fragment)   Streptococcus agalactiae SG-M29 ASA88720.1     1
 BB165_09345   Streptococcus agalactiae SG-M4 ASA99712.1     1
 BB313_09540 (fragment)   Streptococcus agalactiae SG-M50 ASA86666.1     1
 BB162_09490   Streptococcus agalactiae SG-M6 ASA95032.1     1
 BB159_09535   Streptococcus agalactiae SG-M8 ASA92983.1     1
 RDF_1789   Streptococcus agalactiae SS1 AKI96204.1     1
 BBP08_10420 (fragment)   Streptococcus agalactiae WC1535 AOQ21591.1     1
 YM001_08945 (fragment)   Streptococcus agalactiae YM001 AKT98779.1     1
 SANR_1706   Streptococcus anginosus C238 AGU84121.1     1
 ANG_0570   Streptococcus anginosus subsp. whileyi MAS624 BAN61040.1     1
 SCI_1630   Streptococcus constellatus subsp. pharyngis C1050 AGU80529.1     1
 SCRE_1586   Streptococcus constellatus subsp. pharyngis C232 AGU73384.1     1
 SCR2_1586   Streptococcus constellatus subsp. pharyngis C818 AGU75138.1     1
 SDSE167_0698   Streptococcus dysgalactiae subsp. equisimilis 167 BAN93090.1     1
 SDSE_0684   Streptococcus dysgalactiae subsp. equisimilis AC-2713 CCI62182.1     1
 SDE12394_03460   Streptococcus dysgalactiae subsp. equisimilis ATCC 12394 ADX24212.1     1
 SDEG_0643   Streptococcus dysgalactiae subsp. equisimilis GGS_124 BAH81145.1 C5WFI0   1
 GGS_0618   Streptococcus dysgalactiae subsp. equisimilis RE378 BAM60774.1     1
 BMF34_01210   Streptococcus iniae 89353 APD31155.1     1
 CTW00_00805 (HepC)   Streptococcus iniae FP5228 ATX39006.1     1
 DQ08_01035   Streptococcus iniae ISET0901 AHY15095.1     1
 DW64_01030   Streptococcus iniae ISNO AHY16965.1     1
 QMA0248_0226   Streptococcus iniae QMA0248 ASL34074.1     1
 K710_0215   Streptococcus iniae SF1 AGM98020.1     1
 SI82_01285   Streptococcus iniae YSFST01-82 AJG25281.1     1
 SIR_1535   Streptococcus intermedius B196 AGU76886.1     1
 SII_1521   Streptococcus intermedius C270 AGU78685.1     1
 A6J72_07455   Streptococcus intermedius FDAARGOS_233 ARC27023.1     1
 SCIM_1349   Streptococcus intermedius JTH08 BAM24003.1     1
 RN88_07120   Streptococcus intermedius KCOM 1545 ALF28272.1     1
 SITYG_16240   Streptococcus intermedius TYG1620 BAW17603.1     1
 Sequence 4021 from patent US 6699703   Streptococcus pneumoniae AAT16651.1
AAW08509.1
ABI03982.1
ABI09023.1
ABJ32539.1
ABJ50152.1
ABL17895.1
ACK14441.1
ACW45160.1
    1
 SP670_0396   Streptococcus pneumoniae 670-6B ADM90471.1 E0TRK8   1
 SP70585_0391   Streptococcus pneumoniae 70585 ACO16103.1 C1CBA6   1
 T308_01650 (fragment)   Streptococcus pneumoniae A026 AGZ47148.1     1
 T308_01640 (fragment)   Streptococcus pneumoniae A026 AGZ47146.1     1
 A66_00319   Streptococcus pneumoniae A66 CRI61030.1     1
 SPAP_0359   Streptococcus pneumoniae AP200 ADM83952.1 E0SVH3   1
 SPN23F03010   Streptococcus pneumoniae ATCC 700669 CAR68159.1 B8ZL46   1
 SPCG_0333   Streptococcus pneumoniae CGSP14 ACB89585.1 B2ISP8   1
 SPND122_00341   Streptococcus pneumoniae D122 AOG55292.1     1
 SPND141_00343   Streptococcus pneumoniae D141 AOG57373.1     1
 SPND219_00360   Streptococcus pneumoniae D219 ANO36240.1     1
 SPD_0300 (possible fragment)   Streptococcus pneumoniae D39 ABJ55130.1 Q04MD1  
 SPG_0297   Streptococcus pneumoniae G54 ACF55971.1 B5E6Y6   1
 HMPREF1038_00376   Streptococcus pneumoniae gamPNI0373 AFS42452.1     1
 SPNHU15_00399   Streptococcus pneumoniae Hu15 ARD36211.1     1
 SPNHU17_00397   Streptococcus pneumoniae Hu17 ARD34011.1     1
 SPH_0438   Streptococcus pneumoniae Hungary19A-6 ACA37451.1 B1I947   1
 INV104_02730   Streptococcus pneumoniae INV104 CBW35957.1 E1XPF9   1
 SPNINV200_02940   Streptococcus pneumoniae INV200 CBW33928.1 E1XHY6   1
 SPJ_0322   Streptococcus pneumoniae JJA ACO18061.1 C1CCA3   1
 KK0381_20180   Streptococcus pneumoniae KK0381 BAX32138.1     1
 KK0981_23540   Streptococcus pneumoniae KK0981 BAW83850.1     1
 KK1157_21360   Streptococcus pneumoniae KK1157 BAX34433.1     1
 MDRSPN_00301   Streptococcus pneumoniae MDRSPN001 BBA58507.1     1
 ERS445053_00172   Streptococcus pneumoniae NCTC7465 COS99805.1     1
 SpnNT_00320   Streptococcus pneumoniae NT_110_58 AJD71261.1     1
 SPNOXC_03370   Streptococcus pneumoniae OXC141 CBW31997.1 E1XEN9   1
 SPP_0362   Streptococcus pneumoniae P1031 ACO20582.1 C1CIJ2   1
 Spr0297   Streptococcus pneumoniae R6 AAK99101.1
NP_357891.1
Q8CZ74   1
 BMJ42_00438   Streptococcus pneumoniae SP49 APJ29773.1     1
 BOC71_00326   Streptococcus pneumoniae SP61 APJ31846.1     1
 BOC72_00326   Streptococcus pneumoniae SP64 APJ33871.1     1
 SPN034156_13940   Streptococcus pneumoniae SPN034156 SNP034156 CCP37063.1     1
 SPN034183_03440   Streptococcus pneumoniae SPN034183 SNP034183 CCP32054.1     1
 SPN994038_03320   Streptococcus pneumoniae SPN994038 SNP994038 CCP30068.1     1
 SPN994039_03330   Streptococcus pneumoniae SPN994039 SNP994039 CCP34027.1     1
 SPNA45_01710   Streptococcus pneumoniae SPNA45 CCM08995.1     1
 MYY_0409   Streptococcus pneumoniae ST556 AFC94071.1     1
 SPT_0376   Streptococcus pneumoniae Taiwan19F-14 ACO23038.1 C1CPK2   1
 HMPREF0837_10630   Streptococcus pneumoniae TCH8431/19A ADI68858.1 D6ZQG9   1
 SP0329 (fragment)   Streptococcus pneumoniae TIGR4 AAK74505.1
NP_344865.1
   
 SP0327 (probable fragment)   Streptococcus pneumoniae TIGR4 AAK74503.1
NP_344863.1
Q97SK5   1
 STAB904_03065   Streptococcus pyogenes 1E1 AIW11446.1     1
 SP5448_06965   Streptococcus pyogenes 5448 AKK70784.1     1
 STAB1101_02530   Streptococcus pyogenes 7F7 AIT77193.1     1
 A20_0560c   Streptococcus pyogenes A20 AFV37646.1     1
 SPYALAB49_000550   Streptococcus pyogenes Alab49 AEQ24154.1     1
 SPAP1_07300   Streptococcus pyogenes AP1 AKG28411.1     1
 AUQ45_0507   Streptococcus pyogenes AP53 AMY97069.1     1
 DP15_1577   Streptococcus pyogenes ATCC 19615 AIL11568.1     1
 SpyM6D471_02560   Streptococcus pyogenes D471 AKI77512.1     1
 AL510_01090   Streptococcus pyogenes FDAARGOS_149 AMH02543.1     1
 B2G65_07275   Streptococcus pyogenes GUR ASO74520.1     1
 CFA72_07275   Streptococcus pyogenes GURSA1 ASO68805.1     1
 SPYH293_00542   Streptococcus pyogenes H293 CDJ54798.1     1
 CRD75_02680   Streptococcus pyogenes HarveyGAS ATL56503.1     1
 HKU360_00529   Streptococcus pyogenes HKU360 AIW24357.1     1
 HKU488_00433 (HepC)   Streptococcus pyogenes HKU488 AKP81368.1     1
 L897_02790   Streptococcus pyogenes HSC5 AGQ27350.1     1
 JMUB1235_0528   Streptococcus pyogenes JMUB1235 BAV54787.1     1
 SPYJRS4_0520   Streptococcus pyogenes JRS4 BAR44020.1
AKI75841.1
    1
 M1GAS476_0572   Streptococcus pyogenes M1 476 BAM29906.1
BAM29906.2
    1
 SPy0628   Streptococcus pyogenes M1 GAS AAK33596.1
NP_268875.1
Q9A0T7   1
 FE90_0138   Streptococcus pyogenes M23ND AIQ00907.1     1
 ABO05_06830   Streptococcus pyogenes M28PF1 AKJ92983.1     1
 M3B_1521   Streptococcus pyogenes M3-b BAU60886.1     1
 AWM59_06700   Streptococcus pyogenes MEW123 AMA70902.1     1
 AWM58_02635   Streptococcus pyogenes MEW427 AMA68604.1     1
 MGAS10270_Spy0513 + MGAS10270_Spy0512 (fragments)   Streptococcus pyogenes MGAS10270 ABF33577.1
ABF33578.1
   
 M6_Spy0539   Streptococcus pyogenes MGAS10394 AAT86674.1     1
 MGAS10750_Spy0537   Streptococcus pyogenes MGAS10750 ABF37487.1 Q1J7M4   1
 MGAS11027_0530   Streptococcus pyogenes MGAS11027 ANC23535.1     1
 MGAS15252_0544   Streptococcus pyogenes MGAS15252 AFC65895.1     1
 MGAS1882_0541   Streptococcus pyogenes MGAS1882 AFC67764.1     1
 MGAS2096_Spy0530   Streptococcus pyogenes MGAS2096 ABF35582.1 Q1JCS6   1
 MGAS23530_0525   Streptococcus pyogenes MGAS23530 ANC25214.1     1
 MGAS27061_0533   Streptococcus pyogenes MGAS27061 ANC26816.1     1
 SpyM3_0442   Streptococcus pyogenes MGAS315 AAM79049.1
NP_664246.1
Q8K866   1
 M5005_Spy_0518   Streptococcus pyogenes MGAS5005 AAZ51136.1     1
 M28_Spy0497   Streptococcus pyogenes MGAS6180 AAX71611.1     1
 SpyM18_0693   Streptococcus pyogenes MGAS8232 AAL97364.1
NP_606865.1
Q8P1V6   1
 MGAS9429_Spy0509   Streptococcus pyogenes MGAS9429 ABF31697.1 Q1JMQ2   1
 MTB313_0562   Streptococcus pyogenes MTB313 BAQ50974.1     1
 MTB314_0531   Streptococcus pyogenes MTB314 BAQ52701.1     1
 ERS445054_00535   Streptococcus pyogenes NCTC8198 CKG80073.1     1
 SD89_07290   Streptococcus pyogenes NGAS322 AKZ50902.1     1
 DK93_06110   Streptococcus pyogenes NGAS327 AKI39020.1     1
 DK92_06380   Streptococcus pyogenes NGAS596 AKI37441.1     1
 SD90_02625   Streptococcus pyogenes NGAS638 AKZ51829.1     1
 DI45_02845   Streptococcus pyogenes NGAS743 AKI34966.1     1
 A4265_02605   Streptococcus pyogenes NS53 ANC74179.1     1
 Spy49_0524c   Streptococcus pyogenes NZ131 ACI60852.1 B5XKJ0   1
 SPs1413   Streptococcus pyogenes SSI-1 BAC64508.1
NP_802675.1
F7IW17   1
 VT08_02605   Streptococcus pyogenes STAB09014 ANP29128.1     1
 B4W66_02640   Streptococcus pyogenes STAB090229 ASQ20814.1     1
 VU19_02595   Streptococcus pyogenes STAB10015 AKL62741.1     1
 STAB1102_02880   Streptococcus pyogenes STAB1102 AIG48571.1     1
 B5D85_02685   Streptococcus pyogenes STAB120304 ASQ22572.1     1
 AXK13_02955   Streptococcus pyogenes STAB13021 AND04533.1     1
 AYM92_02625   Streptococcus pyogenes STAB14018 ARV00819.1     1
 STAB902_07620   Streptococcus pyogenes STAB902 AIG47681.1     1
 SpyM51345   Streptococcus pyogenes str. Manfredo CAM30673.1 A2RFP4   1
 A6J68_10700   Streptococcus sp. group B FDAARGOS_229 ARC25572.1     1
 HAS68_04770   Streptococcus suis 05HAS68 AHF59040.1     1
 SSU05_1211   Streptococcus suis 05ZYH33 ABP90177.1 A4VVN8   1
 ID09_06425 (possible fragment)   Streptococcus suis 6407 AIG43679.1     1
 AN924_01070   Streptococcus suis 90-1330 AMU78670.1     1
 SSU98_1226   Streptococcus suis 98HAH33 ABP92384.1 A4W1Z5   1
 SSUA7_1062   Streptococcus suis A7 AER44384.1     1
 SSUBM407_0738   Streptococcus suis BM407 CAZ55570.1 C6GXM2   1
 SSUD9_1368   Streptococcus suis D9 AER17554.1     1
 A6M16_03720   Streptococcus suis DN13 ANC99639.1     1
 BFP66_03610   Streptococcus suis GZ0565 AOM75646.1     1
 SSGZ1_1067   Streptococcus suis GZ1 ADE31524.1 D5AI59   1
 A9494_05610   Streptococcus suis LSM102 ARX91399.1     1
 AA105_06995   Streptococcus suis NSUI002 ALA29838.1     1
 APQ97_06110   Streptococcus suis NSUI060 AML46647.1     1
 SSU1048   Streptococcus suis P1/7 CAR46189.1 C5VX48   1
 YYK_04995   Streptococcus suis S735 AFR00518.1     1
 B9H01_05850   Streptococcus suis SC19 ARL70981.1     1
 SSUSC84_1086   Streptococcus suis SC84 CAZ51862.1 C6GNU0   1
 SSU12_1114   Streptococcus suis SS12 AER15297.1     1
 SSUST1_0750   Streptococcus suis ST1 AER21134.1     1
 SSUST3_1224   Streptococcus suis ST3 AEB81649.1     1
 T15_0748   Streptococcus suis T15 AGZ22851.1     1
 YB51_6035   Streptococcus suis YB51 AGW87579.1     1
 ZY05719_05795   Streptococcus suis ZY05719 AKG40500.1     1
 SMD44_08061 (fragment)   Streptomyces alboflavus MDJK44 ARX88574.1     3
 SMD44_08060 (fragment)   Streptomyces alboflavus MDJK44 ARX88573.1     3
 DC74_1127   Streptomyces albulus NK660 AIA01645.1     3
 SAZ_06130   Streptomyces albulus ZPM AKA02055.1     3
 BB341_00315   Streptomyces clavuligerus F613-1 ANW16778.1     3
 SCO0388   Streptomyces coelicolor A3(2) CAB58329.1     3
 KY5_0160c   Streptomyces formicae KY5 ATL25178.1     3
 B1H19_04505   Streptomyces gilvosporeus F607 ARF53532.1     3
 AVL59_31125   Streptomyces griseochromogenes ATCC 14511 ANP53397.1     3
 SHJG_7000   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY92267.1     3
 SHJGH_6760   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF66422.1     3
 SHL15_5752   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO96809.1     3
 SIRAN8055   Streptomyces iranensis CDR13613.1     3
 SLINC_8146   Streptomyces lincolnensis NRRL 2936 ANS70370.1     3
 SLIV_36000   Streptomyces lividans TK24 AIJ18075.1     3
 SNOUR_37240   Streptomyces noursei ATCC 11455 ANZ20676.1     3
 BC342_32190   Streptomyces pactum KLBMP 5084 AOW90409.1     3
 Spa2297_31770   Streptomyces parvulus 2297 ANJ11168.1     3
 LK06_025820   Streptomyces pluripotens MUSC 135 ARP72808.1     3
 LK07_26975   Streptomyces pluripotens MUSC 137 ASN27057.1     3
 SPRI_2006   Streptomyces pristinaespiralis HCCB 10218 ALC20312.1     3
 M271_40870   Streptomyces rapamycinicus NRRL 5491 AGP59552.1     3
 SCAB_23411   Streptomyces scabiei 87.22 CBG69454.1 C9YYZ9   3
 A7J05_09345   Streptomyces silaceus ACCC40021 APY85892.1     3
 SAMN05428941_0443   Streptomyces sp. 2114.2 SDS41365.1     3
 SAMN05444521_7925   Streptomyces sp. 3124.6 SHI57371.1     3
 ASR50_26900   Streptomyces sp. 4F ALV52688.1     3
 GZL_08285   Streptomyces sp. 769 AJC60821.1     3
 T261_7974   Streptomyces sp. A02 AJT69571.1     3
 NI25_00670   Streptomyces sp. CCM_MD2014 AIV32208.1     3
 STRMOE7_01580   Streptomyces sp. MOE7 ARH89223.1     3
 A8713_24580   Streptomyces sp. SAT1 ANH93950.1     3
 SVEN_7193   Streptomyces venezuelae ATCC 10712 CCA60479.1     3
 BN2537_1439   Streptomyces venezuelae ATCC 15439 CUM36237.1     3
 AQF52_7504   Streptomyces venezuelae ATCC 15439 ALO13090.1     3
 SVTN_36070   Streptomyces vietnamensis GIM4.0001 AJF68929.1     3
 Strvi_5605   Streptomyces violaceusniger Tu 4113 AEM85122.1     3
 Sros_3077   Streptosporangium roseum DSM 43021 ACZ86027.1 D2BA14  
 SVA_1548   Sulfurifustis variabilis skN76 BAU48110.1     3
 SYN_02684   Syntrophus aciditrophicus SB ABC78475.1 Q2LWL3  
 LPB136_06550   Tenacibaculum sp. LPB0136 APG65037.1    
 ORF   uncultured bacterium BAR73172.1     1
 ORF (fragment)   uncultured bacterium AIA14495.1     2
 ORF (fragment)   uncultured bacterium AIA16409.1    
 heparinase   uncultured bacterium lac193 AHN98035.1    
 N47_E41710 (fragment)   uncultured Desulfobacterium sp. CBX30659.1 E1YKM6  
 BHY08_00970   Vagococcus teuberi DSM 21459 APB30520.1     1
 SAMN05444156_2604   Verrucomicrobiaceae bacterium GAS474 SDU20698.1    
 Vca1114GL_01731 (HepC)   Vibrio campbellii 1114GL AQM68232.1    
 AKJ08_1056   Vulgatibacter incomptus DSM 27710 AKU90669.1    
 zobellia_1989   Zobellia galactanivorans DsiJT CAZ96066.1     3
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