GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC; UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC; glycogenin glucosyltransferase (EC; inositol 1-α-galactosyltransferase (galactinol synthase) (EC; homogalacturonan α-1,4-galacturonosyltransferase (EC; UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-); UDP-Gal:glucoside α-1,3-galactosyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (13759); Uniprot accession (1210); PDB accession (45); 3D entries (10); cryst (0)
All (12162) Archaea (9) Bacteria (10293) Eukaryota (1683) Viruses (174) unclassified (3) Structure (10) Characterized (53)
Protein Name EC#OrganismGenBank UniprotPDB/3D
 α-N-acetylglucosamine transferase (NagT)   uncultured organism AID69686.1    
 Sequence 2 from patent US 7476778.   unidentified ACN00702.1    
 Sequence 7 from patent US 7476778.   unidentified ACN00705.1    

Last update: 2019-10-16 © Copyright 1998-2019
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