GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (12569); Uniprot accession (1210); PDB accession (43); 3D entries (9); cryst (0)
All (10949) Archaea (9) Bacteria (9171) Eukaryota (1561) Viruses (166) unclassified (42) Structure (9) Characterized (52)
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 α-N-acetylglucosamine transferase (NagT)   uncultured organism AID69686.1    
 Sequence 2 from patent US 7476778.   unidentified ACN00702.1    
 Sequence 7 from patent US 7476778.   unidentified ACN00705.1    
 WN16_03015   Citrobacter sp. ABFQG QBI28222.1    
 WN16_03005   Citrobacter sp. ABFQG QBI28220.1    
 WN16_03010   Citrobacter sp. ABFQG QBI28221.1    
 LCMiAC02_01770   unidentified QBK89084.1    
 LCPAC001_02030   unidentified QBK89690.1    
 LCPAC403_02980   unidentified QBK93164.1    
 LCPAC404_01100   unidentified QBK93406.1    
 LCMAC103_03460   unidentified QBK87002.1    
 E1B03_25590   Citrobacter sp. LY-1 QBM25627.1    
 E1B03_25600   Citrobacter sp. LY-1 QBM25918.1    
 E1B03_25595   Citrobacter sp. LY-1 QBM25628.1    
 E3D81_03210   Sphingobacterium sp. CZ-2 QBR11232.1    
 E2F51_20730   Erwinia sp. QL-Z3 QBR52250.1    
 E2F51_11250   Erwinia sp. QL-Z3 QBR50520.1    
 E4191_12330   Paracoccus sp. 2251 QBX35396.1    
 E4Z61_17585   Citrobacter sp. SNU WT2 QBX82062.1    
 E4Z61_17590   Citrobacter sp. SNU WT2 QBX82063.1    
 E4Z61_17580   Citrobacter sp. SNU WT2 QBX82061.1    
 FA707_08290   Vagococcus sp. MN-17 QCI86965.1    
 C9423_06560   Lactobacillus sp. Koumiss QCJ64016.1    
 C9423_06555   Lactobacillus sp. Koumiss QCJ64015.1    
 FCS00_14540   Elizabethkingia sp. 2-6 QCO47526.1    
 E8L99_12060   Phreatobacter sp. NMCR1094 QCK86435.1    
 RHAL1_5087 (fragment)   Beijerinckiaceae bacterium RH AL1 VTP36575.1    
 RHAL1_3094 (fragment)   Beijerinckiaceae bacterium RH AL1 VTP34593.1    
 RHAL1_3093 (fragment)   Beijerinckiaceae bacterium RH AL1 VTP34592.1    
 RHAL1_5086 (fragment)   Beijerinckiaceae bacterium RH AL1 VTP36574.1    
 FCN45_01985   Pantoea sp. SO10 QCP58227.1    
 FCN45_12240   Pantoea sp. SO10 QCP60103.1    
 FCN45_12450   Pantoea sp. SO10 QCP60141.1    
 FD428_00475   Citrobacter sp. TBCP-5362 QCQ69562.1    
 FD428_00480   Citrobacter sp. TBCP-5362 QCQ69563.1    
 FD428_00470   Citrobacter sp. TBCP-5362 QCQ69561.1    
 FEM41_06085   Izhakiella sp. KSNA2 QCT19256.1    
 FEM41_06080   Izhakiella sp. KSNA2 QCT19255.1    
 FE005_05335   Enterococcus sp. M190262 QCT91415.1    
 FE005_04035 (fragment)   Enterococcus sp. M190262 QCT91180.1    
 FBF37_03980   TM7 phylum sp. oral taxon 957 BB001 QCT42584.1    
 FBF38_03660   TM7 phylum sp. oral taxon 952 TM7x QCT41837.1    
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