| Activities in Family | Hexosyltransferases (EC 2.4.1.-); UDP-Gal α-galactosyltransferase (EC 2.4.1.-); UDP-Gal:glucoside α-1,3-galactosyltransferase (EC 2.4.1.-); UDP-Glc: LOS α-1,3-glucosyltransferase (EC 2.4.1.-); UDP-GlcA: inositol phosphorylceramide α-glucuronosyltransferase (EC 2.4.1.-); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-); UDP-GlcNAc: α-N-acetylglucosaminyltransferase (EC 2.4.1.-); α-1,3-galactosyltransferase (EC 2.4.1.-); α-glucosyltransferase (EC 2.4.1.-); β-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.-); Chiro-inositol 1-α-galactosyltransferase / fagopyritol synthase (EC 2.4.1.-); Homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.-); UDP-Gal: myo-inositol 3-α-galactosyltransferase (EC 2.4.1.123); [retaining] glycogenin α-glucosyltransferase (EC 2.4.1.186); LPS 3-α-galactosyltransferase (EC 2.4.1.44); UDP-Glc: LPS α-glucosyltransferase (EC 2.4.1.58); UDP-Xyl: β-glucoside α-1,3-xylosyltransferase (EC 2.4.2.-); [inverting] UDP-Xyl: protein O-β-xylosyltransferase (EC 2.4.2.-); [retaining] UDP-Xyl: aDXylp-1,3-aDGlcp-O-Ser α-1,3-xylosyltransferase (EC 2.4.2.62); |
|---|---|
| Mechanism | Retaining |
| 3D Structure Status | GT-A |
| Note | Distant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49. |
| External resources | Glymap; HOMSTRAD; |
| Commercial Enzyme Provider(s) | CHEMILY; |
| Statistics | GenBank accession (23958); Uniprot accession (107); PDB accession (63); 3D entries (12); cryst (0) |
| unclassified | |||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | ||
| α-N-acetylglucosamine transferase (NagT) | uncultured organism | AID69686.1 | |||||
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