GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (9581); Uniprot accession (1210); PDB accession (43); 3D entries (9); cryst (0)
All (7969) Archaea (7) Bacteria (6527) Eukaryota (1286) Viruses (146) unclassified (3) Structure (9) Characterized (52)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 13 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF (fragment)   Macaca fascicularis BAE72959.1 Q2PG11  
 unnamed protein product (fragment)   Macaca fascicularis BAE87426.1    
 unnamed protein product (fragment)   Macaca fascicularis BAE89304.1    
 glycosyltransferase 8 domain-containing protein 1 (Glt8d1)   Macaca mulatta AFE65010.1
AFH28382.1
AFI34582.1
   
 glycogenin-1 isoform 2 (Gyg1)   Macaca mulatta AFE77968.1
AFH28165.1
AFI36952.1
   
 ORF   Macaca mulatta AFE80844.1    
 glycogenin-2 isoform a, partial (Gyg2) (fragment)   Macaca mulatta AFE67456.1    
 glucoside xylosyltransferase 1 isoform 1, partial (Gxylt1) (fragment)   Macaca mulatta AFE69972.1    
 xyloside xylosyltransferase 1, partial (C3orf21) (fragment)   Macaca mulatta AFE71065.1    
 glycosyltransferase 8 domain-containing protein 2 precursor, partial (Glt8d2) (fragment)   Macaca mulatta AFE71104.1    
 glycogenin-1 isoform 1 (Gyg1)   Macaca mulatta AFE77967.1    
 glycosyltransferase 8 domain-containing protein 2 (Glt8d2)   Macaca mulatta AFI35876.1    
 MG04092.4   Magnaporthe oryzae 70-15 XP_361618.1 G4NGL9  
 MGG_07493   Magnaporthe oryzae 70-15 XP_003711402.1
XP_367582.1
   
 MSYG_3251 (fragment)   Malassezia sympodialis ATCC 42132 SHO78902.1    
 galactinol synthase 4   Malus domestica AVG45347.1    
 galactinol synthase 1   Malus domestica AVG45344.1    
 galactinol synthase 2   Malus domestica AVG45345.1    
 galactinol synthase 5 (fragment)   Malus domestica AVG45348.1    
 galactinol synthase 3   Malus domestica AVG45346.1    
 ORF (fragment)   Malus domestica AAT79335.1 Q692I4  
 UFGT   Malus domestica AHC31009.1    
 UFGT (fragment)   Malus hybrid cultivar AHA42554.1    
 galactinol synthase (Gols3)   Manihot esculenta AGC51778.1    
 galactinol synthase-2 (Gols2)   Manihot esculenta AHI44616.1    
 galactinol synthase-1 (Gols1)   Manihot esculenta AHI44615.1    
 galactinol synthase (Gols5)   Manihot esculenta AIE11286.1    
 galactinol synthase (Gols4)   Manihot esculenta AIE11287.1    
 galactinol synthase (Gols3)   Manihot esculenta AIE11288.1    
 galactinol synthase (Gols6)   Manihot esculenta AIE11285.1    
 GolS7   Manihot esculenta AIJ00873.1    
 LARGE-2 (fragment)   Mastomys erythroleucus ADI96176.1 D9IFZ6  
 LARGE-2 (fragment)   Mastomys erythroleucus ADI96177.1 D9IFZ7  
 LARGE-2 (fragment)   Mastomys erythroleucus ADI96178.1 D9IFZ8  
 LARGE-2 (fragment)   Mastomys erythroleucus ADI96179.1 D9IFZ9  
 LARGE-2 (fragment)   Mastomys erythroleucus ADI96180.1 D9IG00  
 LARGE-2 (fragment)   Mastomys erythroleucus ADI96181.1 D9IG01  
 LARGE-1 (fragment)   Mastomys erythroleucus ADI96195.1 D9IG15  
 LARGE-1 (fragment)   Mastomys erythroleucus ADI96196.1 D9IG16  
 LARGE-1 (fragment)   Mastomys erythroleucus ADI96197.1 D9IG17  
 LARGE-1 (fragment)   Mastomys erythroleucus ADI96198.1 D9IG18  
 LARGE-1 (fragment)   Mastomys erythroleucus ADI96199.1 D9IG19  
 LARGE-1 (fragment)   Mastomys erythroleucus ADI96200.1 D9IG20  
 LARGE-1 (fragment)   Mastomys erythroleucus ADI96201.1 D9IG21  
 LARGE-2 (fragment)   Mastomys kollmannspergeri ADI96166.1 D9IFY6  
 LARGE-2 (fragment)   Mastomys kollmannspergeri ADI96167.1 D9IFY7  
 LARGE-2 (fragment)   Mastomys kollmannspergeri ADI96168.1 D9IFY8  
 LARGE-1 (fragment)   Mastomys kollmannspergeri ADI96184.1 D9IG04  
 LARGE-1 (fragment)   Mastomys kollmannspergeri ADI96185.1 D9IG05  
 LARGE-1 (fragment)   Mastomys kollmannspergeri ADI96186.1 D9IG06  
 LARGE-1 (fragment)   Mastomys kollmannspergeri ADI96187.1 D9IG07  
 LARGE-2 (fragment)   Mastomys natalensis ADI96169.1 D9IFY9  
 LARGE-2 (fragment)   Mastomys natalensis ADI96170.1 D9IFZ0  
 LARGE-2 (fragment)   Mastomys natalensis ADI96171.1 D9IFZ1  
 LARGE-2 (fragment)   Mastomys natalensis ADI96172.1 D9IFZ2  
 LARGE-2 (fragment)   Mastomys natalensis ADI96173.1 D9IFZ3  
 LARGE-2 (fragment)   Mastomys natalensis ADI96174.1 D9IFZ4  
 LARGE-2 (fragment)   Mastomys natalensis ADI96175.1 D9IFZ5  
 LARGE-1 (fragment)   Mastomys natalensis ADI96188.1 D9IG08  
 LARGE-1 (fragment)   Mastomys natalensis ADI96189.1 D9IG09  
 LARGE-1 (fragment)   Mastomys natalensis ADI96191.1 D9IG11  
 LARGE-1 (fragment)   Mastomys natalensis ADI96192.1 D9IG12  
 LARGE-1 (fragment)   Mastomys natalensis ADI96193.1 D9IG13  
 LARGE-1 (fragment)   Mastomys natalensis ADI96194.1 D9IG14  
 galactinol synthase (CorF)   Medicago falcata ACM50915.1 B9VV96  
 galactinol synthase (CorF) 2.4.1.123 Medicago sativa AAM97493.1 Q84MZ5  
 galactinol synthase 2 (GolS2) (fragment)   Medicago sativa CAF21715.1 Q703J2  
 MTYFL_FM_FN_FO1G-L-16 (fragment)   Medicago truncatula ACJ83784.1 B7FGC6  
 MTYFD_FE_FF_FG1G-F-3 (fragment)   Medicago truncatula ACJ85290.1 B7FKK6  
 MTYFL_FM_FN_FO1G-L-16 (fragment)   Medicago truncatula ACJ85766.1 B7FLY3  
 unknown (fragment)   Medicago truncatula AFK37519.1    
 unknown   Medicago truncatula AFK39430.1    
 unknown (fragment)   Medicago truncatula AFK41072.1    
 MtrDRAFT_AC147483g3v1 or MtrDRAFT_AC137839g25v1   Medicago truncatula ABE80667.2
ABE78500.1
ABE80667.1
ABO82396.1
   
 MtrDRAFT_AC145329g1v1   Medicago truncatula ABE91008.1 G7KSQ7  
 MtrDRAFT_AC146721g10v1   Medicago truncatula ABE89660.1 G7ZV05  
 MtrDRAFT_AC151424g8v1   Medicago truncatula ABE88904.1 G7I3L2  
 MtrDRAFT_AC151424g7v1   Medicago truncatula ABE88903.1 G7I3L3  
 MtrDRAFT_AC135465g9v1   Medicago truncatula ABE87756.1 G7KTP3  
 MtrDRAFT_AC155898g16v1   Medicago truncatula ABE87702.1
ABO83841.1
   
 MtrDRAFT_AC138087g9v1   Medicago truncatula ABE80888.1
CAW96603.1
CAW96805.1
CAX04122.1
CAX05902.1
CBD13108.1
G7JIW7  
 MtrDRAFT_AC137832g30v2   Medicago truncatula ABE86959.1
AFK41069.1
G7KJH6  
 MtrDRAFT_AC155890g1v2   Medicago truncatula ABN08312.1 A2Q3W2  
 MtrDRAFT_AC161399g30v2   Medicago truncatula ABN08854.1 A2Q5F4  
 MtrDRAFT_AC137701g1v2   Medicago truncatula ABO79665.1    
 MtrDRAFT_AC154090g8v1+ MtrDRAFT_AC154090g16v1 (fragments)   Medicago truncatula ABO83708.1
ABO83709.1
   
 MtrDRAFT_AC151426g12v1   Medicago truncatula ABP03325.1    
 BN887_00734   Melanopsichium pennsylvanicum 4 CDI52045.1    
 BN887_00256   Melanopsichium pennsylvanicum 4 CDI54499.1    
 galactinol synthase, partial (Gols1) (fragment)   Mentha sp. MC-2012 AFD50394.1    
 galactinol synthase, partial (Gols1) (fragment)   Micromeria hyssopifolia AFD50392.1    
 galactinol synthase, partial (Gols1) (fragment)   Micromeria lanata AFD50389.1    
 galactinol synthase, partial (Gols1) (fragment)   Micromeria tenuis AFD50395.1    
 galactinol synthase, partial (Gols1) (fragment)   Micromeria varia AFD50390.1    
 galactinol synthase, partial (Gols1) (fragment)   Micromeria varia AFD50393.1    
 galactinol synthase, partial (Gols1) (fragment)   Micromeria varia AFD50396.1    
 GNLVRS01_PISO0N00959g (Piso0_004779)   Millerozyma farinosa CBS 7064 CCE86296.1    
 GNLVRS01_PISO0M00804g (Piso0_004779)   Millerozyma farinosa CBS 7064 CCE85197.1    
 GAS1 (fragment)   Momordica charantia AAQ74882.1 Q6U2M9  
 ORF (fragment)   Mucor racemosus PTCC 5305 ABW74133.1 A8W7G8  
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