GlycosylTransferase Family 8

Activities in Familylipopolysaccharide α-1,3-galactosyltransferase (EC 2.4.1.44); UDP-Glc: (glucosyl)lipopolysaccharide α-1,2-glucosyltransferase (EC 2.4.1.-); lipopolysaccharide glucosyltransferase 1 (EC 2.4.1.58); glycogenin glucosyltransferase (EC 2.4.1.186); inositol 1-α-galactosyltransferase (galactinol synthase) (EC 2.4.1.123); homogalacturonan α-1,4-galacturonosyltransferase (EC 2.4.1.43); UDP-GlcA: xylan α-glucuronyltransferase (EC 2.4.1.-)
Mechanism Retaining
3D Structure StatusGT-A
NoteDistant similarity to family GT24; The animal LARGE bifunctional glycosyltransferases are made of two domains. The N-terminal domain, which adds a-1,3-Xyl residues, belongs to family GT8 while the C-terminal domain, which adds b-1,3-GlcA residues, belongs to family GT49.
External resourcesGlymap; HOMSTRAD;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (8766); Uniprot accession (1210); PDB accession (41); 3D entries (9); cryst (0)
All (7156) Archaea (7) Bacteria (5752) Eukaryota (1256) Viruses (138) unclassified (3) Structure (9) Characterized (52)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 13 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 predicted protein   Hordeum vulgare subsp. vulgare BAK04525.1    
 predicted protein   Hordeum vulgare subsp. vulgare BAK04626.1    
 predicted protein (fragment)   Hordeum vulgare subsp. vulgare BAJ88752.1    
 predicted protein (fragment)   Hordeum vulgare subsp. vulgare BAK08103.1    
 ORF (fragment)   Hymenochirus curtipes AEQ18068.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56525.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56520.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56543.1    
 Gl8d2   Ictalurus furcatus ADO27988.1 E3TCF2  
 GlyG   Ictalurus furcatus ADO28088.1 E3TCQ2  
 GlyG   Ictalurus punctatus ADO28439.1 E3TDQ3  
 ORF (Glt8d2)   Ictalurus punctatus AHH40322.1    
 ORF (Gxylt2)   Ictalurus punctatus AHH37280.1    
 ORF (Gyltl1B)   Ictalurus punctatus AHH39116.1    
 ORF LARGE   Ictalurus punctatus AHH40413.1    
 ORF (Gxylt1)   Ictalurus punctatus AHH42702.1    
 JcGS   Jatropha curcas AIC83905.1    
 JHL05D22.8 (Jhl05d22.8)   Jatropha curcas Palawan BAJ53137.1    
 Galactinol synthase (GS)   Juglans sigillata ASU91336.1    
 galactinol synthase 4, partial (Gols4) (fragment)   Kalmia procumbens BBA94726.1
BBA94727.1
BBA94728.1
BBA94729.1
BBA94730.1
BBA94731.1
BBA94732.1
BBA94733.1
BBA94734.1
BBA94735.1
BBA94736.1
BBA94737.1
BBA94738.1
BBA94739.1
BBA94740.1
BBA94741.1
BBA94742.1
BBA94743.1
BBA94744.1
BBA94745.1
BBA94746.1
BBA94747.1
BBA94748.1
BBA94749.1
BBA94750.1
BBA94751.1
BBA94752.1
BBA94753.1
BBA94754.1
BBA94755.1
BBA94756.1
BBA94757.1
BBA94758.1
BBA94759.1
BBA94760.1
BBA94761.1
BBA94762.1
BBA94763.1
BBA94764.1
BBA94765.1
BBA94766.1
BBA94767.1
BBA94768.1
BBA94769.1
BBA94770.1
BBA94771.1
BBA94772.1
BBA94773.1
BBA94774.1
BBA94775.1
BBA94776.1
BBA94777.1
BBA94778.1
BBA94779.1
BBA94780.1
BBA94781.1
BBA94782.1
BBA94783.1
BBA94784.1
BBA94785.1
BBA94786.1
BBA94787.1
BBA94788.1
BBA94789.1
BBA94790.1
BBA94791.1
BBA94792.1
BBA94793.1
BBA94794.1
BBA94795.1
BBA94796.1
BBA94797.1
BBA94798.1
   
 KAFR_0B03610 (Kafr0b03610)   Kazachstania africana CBS 2517 CCF56658.1    
 KAFR_0G00660 (Kafr0g00660)   Kazachstania africana CBS 2517 CCF59099.1    
 KNAG_0C01230 (Knag0c01230)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK69236.1    
 KNAG_0J00550 (Knag0j00550)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK72138.1    
 α-N-acetylglucosaminyltransferase (Gnt1)   Kluyveromyces lactis AAD25740.1 Q9Y761  
 KLLA0B03135g (Gnt1)   Kluyveromyces lactis NRRL Y-1140 CAH02065.1 Q9Y761  
 KLLA0C14366g   Kluyveromyces lactis NRRL Y-1140 CAH01694.1 Q6CT96  
 KLLA0A05709g   Kluyveromyces lactis NRRL Y-1140 CAY34853.1
CAH02842.1
   
 KLMA_10347   Kluyveromyces marxianus DMKU3-1042 BAO37969.1    
 KLMA_30559   Kluyveromyces marxianus DMKU3-1042 BAO39854.1    
 KLMA_40461   Kluyveromyces marxianus DMKU3-1042 BAO40485.1    
 KMAR_10313   Kluyveromyces marxianus NBRC 1777 BAP69521.1    
 KMAR_40461   Kluyveromyces marxianus NBRC 1777 BAP71969.1    
 KMAR_30532   Kluyveromyces marxianus NBRC 1777 BAP71337.1    
 ATY40_BA7504460 (Glg1)   Komagataella pastoris ATCC 28485 ANZ77551.1    
 ATY40_BA7500240   Komagataella pastoris ATCC 28485 ANZ73957.1    
 AT249_GQ6705240 (Glg1)   Komagataella phaffii ATCC 76273 AOA64676.1    
 AT249_GQ6703282   Komagataella phaffii ATCC 76273 AOA63750.1    
 PP7435_Chr3-0992   Komagataella phaffii CBS 7435 CCA39938.1
SOP82666.1
   
 PP7435_Chr4-0104   Komagataella phaffii CBS 7435 CCA40280.1
SOP83030.1
   
 PAS_chr3_0231   Komagataella phaffii GS115 CAY70253.1
AOA69134.1
C4R3Y2  
 PAS_chr4_0847   Komagataella phaffii GS115 CAY72116.1
AOA69459.1
C4R941  
 KLTH0E14014g   Lachancea thermotolerans CBS 6340 CAR23651.1    
 KLTH0F05632g   Lachancea thermotolerans CBS 6340 CAR24013.1    
 galactinol synthase, partial (Gols1) (fragment)   Lavandula angustifolia AFD50391.1    
 galactinol synthase 1 (Gols1)   Lens culinaris ALO17645.1    
 galactinol synthase 1 (Gols1)   Lens culinaris ALO17647.1    
 galactinol synthase 1 (Gols1)   Lens culinaris ALO17646.1    
 galactinol synthase 2 (Gols2)   Lens culinaris ALO17648.1    
 galactinol synthase 2 (Gols2)   Lens culinaris ALO17650.1    
 galactinol synthase 2 (Gols2)   Lens culinaris ALO17649.1    
 galactinol synthase 1 (Gols1)   Lens culinaris ALO17651.1    
 glycogenin (Glgen)   Lentinula edodes L54A AEN14434.1    
 glycogenin-1 (GlyG)   Lepeophtheirus salmonis Pacific form ACO11990.1 C1BSI7  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX98248.1 E5A3N5  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX98687.1 E5A4Y9  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY01261.1 E5ADH2  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX91702.1 E4ZKA7  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX95847.1 E4ZW71  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX96081.1 E4ZWV5  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX97186.1 E5A0P0  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY00837.1 E5AAZ6  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY01000.1 E5ABF9  
 LRAMOSA09708   Lichtheimia ramosa CDS07185.1    
 LRAMOSA05197   Lichtheimia ramosa CDS13013.1    
 LRAMOSA09648   Lichtheimia ramosa CDS07125.1    
 pollen product (LLP-29) (fragment)   Lilium longiflorum ABM68549.1 A6MGY5  
 galactinol synthase 1 (fragment)   Lolium perenne AAN52770.1 Q8H1B9  
 galactinol synthase 2 (fragment)   Lolium perenne AAN52771.1 Q8H1B8  
 galactinol synthase 3 (fragment)   Lolium perenne AAO20083.1 Q84XZ2  
 unknown   Lotus japonicus AFK39755.1    
 unknown (fragment)   Lotus japonicus AFK41629.1    
 GAS1 (fragment)   Luffa aegyptiaca AAQ74880.1 Q6U2N1  
 ORF (fragment)   Lumnitzera racemosa AGU71343.1    
 ORF8   Lupinus angustifolius CCH47207.1    
 ORF   Macaca fascicularis BAE01868.1 Q4R4V7  
 ORF   Macaca fascicularis BAE02219.1 Q4R3U7  
 ORF (fragment)   Macaca fascicularis BAE72959.1 Q2PG11  
 unnamed protein product (fragment)   Macaca fascicularis BAE87426.1    
 unnamed protein product (fragment)   Macaca fascicularis BAE89304.1    
 glycosyltransferase 8 domain-containing protein 1 (Glt8d1)   Macaca mulatta AFE65010.1
AFH28382.1
AFI34582.1
   
 glycogenin-1 isoform 2 (Gyg1)   Macaca mulatta AFE77968.1
AFH28165.1
AFI36952.1
   
 ORF   Macaca mulatta AFE80844.1    
 glycogenin-2 isoform a, partial (Gyg2) (fragment)   Macaca mulatta AFE67456.1    
 glucoside xylosyltransferase 1 isoform 1, partial (Gxylt1) (fragment)   Macaca mulatta AFE69972.1    
 xyloside xylosyltransferase 1, partial (C3orf21) (fragment)   Macaca mulatta AFE71065.1    
 glycosyltransferase 8 domain-containing protein 2 precursor, partial (Glt8d2) (fragment)   Macaca mulatta AFE71104.1    
 glycogenin-1 isoform 1 (Gyg1)   Macaca mulatta AFE77967.1    
 glycosyltransferase 8 domain-containing protein 2 (Glt8d2)   Macaca mulatta AFI35876.1    
 MG04092.4   Magnaporthe oryzae 70-15 XP_361618.1 G4NGL9  
 MGG_07493   Magnaporthe oryzae 70-15 XP_003711402.1
XP_367582.1
   
 MSYG_3251 (fragment)   Malassezia sympodialis ATCC 42132 SHO78902.1    
 ORF (fragment)   Malus domestica AAT79335.1 Q692I4  
 UFGT   Malus domestica AHC31009.1    
 UFGT (fragment)   Malus hybrid cultivar AHA42554.1    
 galactinol synthase (Gols3)   Manihot esculenta AGC51778.1    
 galactinol synthase-2 (Gols2)   Manihot esculenta AHI44616.1    
 galactinol synthase-1 (Gols1)   Manihot esculenta AHI44615.1    
 galactinol synthase (Gols5)   Manihot esculenta AIE11286.1    
 galactinol synthase (Gols4)   Manihot esculenta AIE11287.1    
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