GlycosylTransferase Family 7

Activities in Familylactose synthase (EC 2.4.1.22); β-N-acetylglucosaminyl-glycopeptide β-1,4-galactosyltransferase (EC 2.4.1.38); N-acetyllactosamine synthase (EC 2.4.1.90); xylosylprotein β-4-galactosyltransferase (EC 2.4.1.133); UDP-Gal: neolactotriaosylceramide β-1,4-galactosyltransferase (EC 2.4.1.275); β-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.-)
Mechanism Inverting
3D Structure StatusGT-A
External resourcesCFG(Glycosphingolipid); CFG(O-linked); CFG(Terminal); Glymap;
Commercial Enzyme Provider(s)CHEMILY;
Statistics GenBank accession (891); Uniprot accession (199); PDB accession (50); 3D entries (4); cryst (0)
All (292) Archaea (1) Bacteria (12) Eukaryota (272) Viruses (7) Structure (4) Characterized (33)
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 β-1,4-galactosyltransferase T1 (B4Gal-T1;GgtB2;GalT) 2.4.1.22
2.4.1.38
2.4.1.90
Bos taurus AAA30534.1
AAA30659.1
AAI20416.1
AAM54035.2
CAA32695.1
NP_803478.1
P08037
1FGX[A,B] 2.40
1FR8[A,B] 2.40
1J8W[B] β-D-Glcp
2.00
1J8X[B] 2.00
1J92[B] β-D-GlcpNAc
2.00
1J94[B] 2.50
1JN8[B] β-D-GlcpNAc
2.00
1JNA[B] <non_carb>-(1-2)-β-D-GlcpN
2.30
1JNC[B] 2.30
1KYB[A] α-D-Galp-(1-1)-<non_carb>
2.80
1L7W[B] 2.10
1NF5[B,D] β-D-Glcp
2.00
1NHE[B,D] 2.50
1NKH[B,D] 2.00
1NMM[B,D] β-D-GlcpNAc
2.00
1NQI[B,D] β-D-GlcpNAc
2.00
1NT7[B] 2.32
1NWG[B,D] <non_carb>-(1-2)-β-D-GlcpN
2.32
1O0R[A,B] α-D-Galp-(1-1)-<non_carb>
2.30
1O23[B,D] 2.32
1OQM[B,D] 2.10
1TVY[A,B] α-D-Galp-(1-1)-<non_carb>
2.30
1TW1[A,B] 2.30
1TW5[A,B] β-D-GlcpNAc-(1-4)-β-D-GlcpNAc
2.30
1YRO[B,D] α-D-Galp-(1-1)-<non_carb>
1.90
2FYC[B,D] α-D-Galp-(1-1)-<non_carb>
2.00
2FYD[B,D] β-D-GalpNAc-(1-4)-β-D-Glcp
2.00
4KRV[A,B] β-D-GlcpNAc6SO3
2.40
 xylosylprotein β-4-galactosyltransferase I / 7 (bGalT7/CG11780) 2.4.1.133 Drosophila melanogaster AAF56377.1
AAM11018.1
BAC22695.1
NP_651319.2
Q8I6J0
Q8T3P3
Q9VBZ9
3LW6[A] 1.81
4LW3[A] α-D-Galp-(1-1)-<non_carb>
2.00
4LW6[A] β-D-Xylp-(1-4)-β-D-Xylp
2.40
4M4K[A] α-D-Galp-(1-1)-<non_carb>
β-D-Xylp-(1-4)-β-D-Xylp
2.20
 UDP-Gal: β-GlcNAc β-1,4-galactosyltransferase T1 (b4GalT1;beta4GalT-I;GalT) 2.4.1.38
2.4.1.90
Homo sapiens CAA39073.1
AAA35935.1
AAA35936.1
AAA68218.1
AAA68219.1
AAA68220.1
AAB00776.1
AAH45773.1
AAP66230.1
ABA16640.1
ABE21039.1
ACG93380.1
BAA06188.1
BAG59480.1
BAG59940.1
BAH14665.1
CAA01685.1
CAA31611.1
CAA32247.1
CAA39074.1
CAD13306.1
CAD62044.1
CAL47686.1
CAT03462.1
CDJ98631.1
CDJ98633.1
NP_001488.2
B2R710
D3DRL2
P15291
Q86XA6
2AE7[A,B,C] β-D-GlcpNAc-(1-2)-α-D-Manp
β-D-GlcpNAc-(1-2)-α-D-Manp-(1-6)-β-D-Manp
2.00
2AEC[A,B,C] β-D-GlcpNAc-(1-2)-α-D-Manp-(1-6)-β-D-Manp
2.00
2AES[A,B,C] β-D-GlcpNAc-(1-2)-α-D-Manp-(1-3)-β-D-Manp
2.00
2AGD[A,B,C] β-D-GlcpNAc-(1-4)-α-D-Manp-(1-3)-β-D-Manp
1.90
2AH9[A,B,C] β-D-GlcpNAc-(1-4)-β-D-GlcpNAc-(1-4)-β-D-GlcpNAc
2.00
2FY7[A] 1.70
2FYA[A] 1.90
3EE5[A,B,C] β-D-GlcpNAc-(1-3)-β-D-Galp-(1-1)-<non_carb>
2.20
4EE3[A,B,C] β-D-4-deoxy-Glcp-(1-3)-β-D-GlcpNAc-(1-3)[β-D-GlcpNAc-(1-6)]-β-D-Galp-(1-4)-β-D-Glcp
β-D-Galp-(1-3)-β-D-GlcpNAc-(1-3)[β-D-GlcpNAc-(1-6)]-β-D-Galp-(1-4)-β-D-Glcp
2.30
4EE4[A,B,C] β-D-GlcpNAc-(1-6)[β-D-GlcpNAc-(1-3)]-β-D-Galp-(1-4)-β-D-Glcp
1.95
4EE5[A,B,C] β-D-GlcpNAc-(1-3)-β-D-Galp-(1-4)-β-D-Glcp
2.20
4EEA[A,B,C] β-D-GlcpNAc-(1-6)-β-D-Galp-(1-4)-β-D-Glcp
2.00
4EEG[A,B,C] β-D-GlcpNAc-(1-6)-β-D-Galp
2.20
4EEM[A,B,C] β-D-GlcpNAc-(1-6)-α-D-Manp-(1-1)-methyl
2.20
4EEO[A,B,C] β-D-GlcpNAc-(1-6)-α-D-GlcpNAc-(1-1)-<non_carb>
2.30
4L41[C] 2.70
 UDP-Gal: xylosylprotein β-1,4-galactosyltransferase-I / VII / 7 (GalT-I;B4GALT7) 2.4.1.133 Homo sapiens AAH07317.1
AAF22225.1
AAH62983.1
AAH72403.1
AAP63346.1
AAQ88941.1
AAW16345.1
ABA31378.1
ABA36378.1
ABA37874.1
ABA37960.1
ABA68637.1
ABA69640.1
ABA70022.1
ABA70145.1
ABA82167.1
ABC03966.1
ABC16001.1
ABE23456.1
ABE26019.1
ABE26292.1
ABH64529.1
ABH64652.1
ABH64809.1
ABH66038.1
ABH70857.1
ABH70980.1
ABH72494.1
ABH75609.1
ABH99394.1
ABI02499.1
ABI07300.1
ABI10948.1
ABI12292.1
ABJ19333.1
ABJ34328.1
ABJ43360.1
ABX96323.1
ABX96633.1
ABY05097.1
ABY16036.1
ABY18833.1
ABY19001.1
ACE08824.1
ACJ96363.1
ACM85403.1
ACM95141.1
ACN00233.1
ACN08780.1
ACP73896.1
ACS06522.1
ACS08554.1
ACW23889.1
BAA83414.1
BAG51093.1
BAG51201.1
BAG53157.1
CAB56424.1
CAC24978.1
CAE90482.1
CAE91032.1
CAE93781.1
CAF14401.1
CAM55968.1
NP_009186.1
B3KN39
Q9UBV7
Q9UBV7
4IRP[A,B] 2.10
4IRQ[A,B,C,D] 2.30
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