GlycosylTransferase Family 68

Activities in Family	GDP-L-Fuc: protein O-α-L-fucosyltransferase (EC 2.4.1.221);
Mechanism	Inverting
3D Structure Status	GT-B
Note	Distantly related to families GT65, GT23, GT11; created after reading Martinez-Dunker et al. (2003) Glycobiology 13:1C-5C
External resources	Glymap;
Statistics	GenBank accession (191); Uniprot accession (9); PDB accession (4); 3D entries (2); cryst (0)

Summary

Download GT68 (149) Taxonomic display Structure (2) Characterized (3)

Eukaryota

Protein Name

EC#

Organism

GenBank

Uniprot

PDB/3D

Carbohydrate Ligands

Resolution (Å)

protein O-fucosyltransferase 2 (Pad-2; CePOFUT2; K10G9.3)

2.4.1.221

Caenorhabditis elegans Bristol N2

CAD45602.1
AAL65193.1
CCC42186.1
NP_741272.1

G1K0W1
Q8WR51

5FOE[A,B]		1.98
8AY1[A,B]		2.13

GDP-L-Fuc: protein O-fucosyltransferase 2 (POFUT2; C21orf80; FUT13; KIAA0958)

2.4.1.221

Homo sapiens

AAL47681.2
AAH11044.1
AAH64623.1
BAA76802.1
BAA76802.2
BAF83421.1
BAG58039.1
BAG60368.1
CAB53715.2
CAB90496.1
CAC24556.1
CAC24557.1
CAE01472.1
CDG37810.1
CDG37811.1
NP_056042.1
NP_598367.1
NP_598368.2

A8K3W7
B4DH78
B4DNV6
Q9Y2G5
S6FMI4
S6FW71

4AP5[A,B]		3.00
4AP6[A,B,C,D]	β-L-Fucp-(1-1)-<non_carb>	3.401

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