GlycosylTransferase Family 65

Activities in FamilyGDP-Fuc: protein O-α-fucosyltransferase (EC 2.4.1.-)
Mechanism Inverting
3D Structure StatusGT-B
NoteDistantly related to families GT68, GT23, GT11
External resourcesGlymap;
Statistics GenBank accession (98); Uniprot accession (34); PDB accession (17); 3D entries (3); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 protein O-fucosyltransferase 1 (pofut1) (fragment)   Aedes aegypti ABA29465.1 Q00P44  
 protein O-fucosyltransferase 1 (pofut1)   Anopheles gambiae ABA29466.1 Q7QHS7  
 ACCB11913 (fragment)   Apis cerana AEY61335.1    
 ORF   Ascaris suum ADY46235.1    
 protein-O-fucosyltransferase 1 (Fut12) (fragment)   Bombyx mori ABA29467.1
CAH40835.1
Q00P42  
 protein O-fucosyltransferase 1a / 1b / 1c / 1d / 1e (Pofut1a;Pofut1b;Pofut1c;Pofut1d;Pofut1e;Pofut1)   Bos taurus AAQ02332.1
AAI26763.1
AAQ02333.1
AAX46690.1
ABA29449.1
ABA29450.1
ABA29451.1
CAH03714.1
NP_892031.1
Q7YRE6
Q7YRE7
 
 protein-O-fucosyltransferase 1 (Fut12)   Caenorhabditis briggsae CAH40833.1
ABA29470.1
Q659S2  
 GDP-Fuc: protein O-fucosyltransferase 1 (PoFut1;CePOFUT1;C15C7.7)   Caenorhabditis elegans Bristol N2 CCD64591.1
AAM51514.2
ABA29469.1
NP_741744.2
Q00P41
Q18014
3ZY2[A]
3ZY3[A,B]
3ZY4[A]
3ZY5[A]
3ZY6[A]
 ORF   Callorhinchus milii AFP05470.1    
 protein O-fucosyltransferase 1 (pofut1)   Canis lupus familiaris ABA29461.1 Q00P48  
 protein-O-fucosyltransferase 1 (Fut12)   Ciona savignyi CAH03713.1 Q6EV67  
 GDP-L-Fuc: protein O-α-L-fucosyltransferase 1 (Fut12) 2.4.1.221 Danio rerio CAE18459.1
AAH95289.1
AAI65557.1
NP_991281.1
Q7T028  
 Dbus_chr2Rg1399   Drosophila busckii ALC41820.1    
 GDP-L-Fuc: protein O-α-L-fucosyltransferase (CG12366-PA;O-fut1;Ofut1;Nti;FI01906p) 2.4.1.221 Drosophila melanogaster AAF58290.1
AAX33443.1
ABV82190.1
AHN56204.1
BAC55010.1
NP_610931.1
A8E6L6
Q9V6X7
Q9V6X7
 
 protein-O-fucosyltransferase 1 (Fut12;Pofut1)   Drosophila pseudoobscura CAH03716.1
ABA29468.1
   
 protein-O-fucosyltransferase 1 (Fut12)   Drosophila yakuba CAH40834.1 Q659S1  
 Pofut1   Gallus gallus CAD59738.1
CAG31244.1
CAG32011.1
Q8AWB4  
 GDP-L-Fuc: protein O-fucosyltransferase 1 (PoFUT1) 2.4.1.221 Homo sapiens AAL09576.1
AAH00582.1
BAA11497.2
BAA11497.3
BAF83722.1
BAG62466.1
BAG64185.1
CAC16424.1
CAH73300.1
NP_056167.1
NP_758436.1
A8K4R8
Q9H488
5UX6[A,B]
5UXH[A,B]
 ORF (Pofut1)   Ictalurus punctatus AHH38183.1    
 unnamed protein product   Macaca fascicularis BAE88386.1    
 GDP-fucose protein O-fucosyltransferase 1 isoform 1 precursor (Pofut1)   Macaca mulatta AFE77472.1
AFH31753.1
AFH31754.1
AFH31755.1
AFH31756.1
AFH31757.1
AFH31758.1
AFH31759.1
AFH31760.1
AFH31761.1
   
 GDP-L-Fuc: protein O-fucosyltransferase (Pofut1) 2.4.1.221 Mus musculus AAL09577.1
AAH46295.1
BAC32009.1
BAD90237.1
BAE21090.1
BAE22596.1
CAM17074.1
CAM17075.1
CAM17076.1
NP_536711.1
A2AMC4
Q91ZW2
Q91ZW2
5KXH[A]
5KXQ[A,B,C,D]
5KY0[A]
5KY2[A]
5KY3[A]
5KY4[A]
5KY5[A]
5KY7[A]
5KY8[A]
5KY9[A]
 ORF   Mustela putorius furo AES04394.1    
 protein-O-fucosyltransferase 1 (Fut12)   Onchocerca volvulus CAH40836.1 Q659R9  
 protein O-fucosyltransferase 1 (Pofut1)   Oryzias latipes ABA29462.1 Q00P47  
 GDP-L-Fuc: protein O-fucosyltransferase 1 (Fut12)   Pan troglodytes CAH03712.1 Q6EV69  
 DKFZp459B068   Pongo abelii CAH91412.1 Q5R9Z8  
 ORF   Pseudocentrotus depressus BAJ23058.1 E2S055  
 protein-O-fucosyltransferase 1 (Fut12)   Rattus norvegicus WISTAR CAH03711.1 Q6EV70  
 SJCHGC07164 (short fragment)   Schistosoma japonicum AAX30722.2 Q5BRW3  
 protein O-fucosyltransferase A (PoFuctA;Smp_065240)   Schistosoma mansoni Puerto Rico AEW22974.1
CAZ34014.1
CCD77704.1
C4QEX8  
 protein O-fucosyltransferase 1 (Pofut1;O-FucT-1)   Strongylocentrotus purpuratus ABA29464.1 Q00P45  
 SRAE_2000487500   Strongyloides ratti ED321 Heterogonic CEF70241.1    
 protein-O-fucosyltransferase (Pofut1)   Sus scrofa ABA29460.1
CAD99201.1
Q00P49
Q7YRZ3
 
 protein-O-fucosyltransferase (Fut12)   Takifugu rubripes CAE54305.1 Q70AG7  
 protein-O-fucosyltransferase 1 (Fut12)   Tetraodon nigroviridis CAH03715.1
ABA29463.1
Q6EV65  
 Pofut1   Xenopus laevis CAD55833.1
AAI06427.1
Q8AXS8  
 protein-O-fucosyltransferase (Fut12;PoFut1;LOC496411)   Xenopus tropicalis CAH03710.1
AAH82519.1
AAH82519.2
CAJ82404.1
Q6EV71  
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