Activities in Family	UDP-GlcNAc: heparan α-N-acetylhexosaminyltransferase (EC 2.4.1.224)
Mechanism	Retaining
3D Structure Status	GT-A
Note	The long animal heparan synthases are made of two domains. The N-terminal domain, which adds b-1,4-GlcA residues, belongs to family GT47 while the C-terminal domain, which adds a-1,4-GlcNAc residues, belongs to family GT64. The plant homologs have a single domain.
External resources	Glymap;
Statistics	GenBank accession (477); Uniprot accession (31); PDB accession (4); 3D entries (1); cryst (0)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
UDP-GlcNAc: α-1,4-N-acetylglucosaminyltransferase (Extl2)	2.4.1.223	Mus musculus	AAG17542.1 AAH31438.1 AAH94444.1 BAB31683.2 BAC26062.1 BAC27649.1 BAE34959.1 BAE36615.1 BAM48568.1 BAM48569.1 NP_067363.1	K0J1C6 Q3TSR0 Q3TXF7 Q8C089 Q8C197 Q9ES89	1OMX[A,B] 2.40 1OMZ[A,B] 2.10 1ON6[A,B] 2.30 1ON8[A,B] β-D-GlcpA-(1-3)-β-D-Galp 2.70
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