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GlycosylTransferase Family 64

Known ActivitiesUDP-GlcNAc: heparan α-N-acetylhexosaminyltransferase (EC 2.4.1.224)
Mechanism Retaining
3D Structure StatusGT-A
NoteThe long animal heparan synthases are made of two domains. The N-terminal domain, which adds b-1,4-GlcA residues, belongs to family GT47 while the C-terminal domain, which adds a-1,4-GlcNAc residues, belongs to family GT64. The plant homologs have a single domain.
Statistics GenBank accession (214); Uniprot accession (84); PDB accession (4); 3D entries (1); cryst (0)
Summary
All (79) Eukaryota (79) Structure (1 ) Characterized (10)
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 At3g55830/F27K19_10 (Epc1)   Arabidopsis thaliana AEE79446.1
BAF00425.1
CAB87837.1
NP_191142.1		 Q9LY62  
 At5g04500/T32M21_100   Arabidopsis thaliana AAO42055.1
AED90753.1
CAB85556.1
NP_196070.1
NP_196070.2		 Q84WB7
Q9LZ75		  
 At1g80290/F5I6.4   Arabidopsis thaliana AAF27686.1
AAG52433.1
AAM61012.1
ABD59059.1
AEE36383.1
AEE36384.1
BAH20131.1
NP_565236.1		 Q8LG66
Q9C975		  
 ORF   Ascaris suum ADY41945.1    
 ORF   Ascaris suum ADY42536.1    
 Unknown (protein for MGC:137797)   Bos taurus AAI14731.1 Q1RMT0  
 Unknown (protein for MGC:155111)   Bos taurus AAI33541.1 A2VE26  
 Unknown (protein for MGC:151773)   Bos taurus AAI40569.1 A5D7I4  
 β-glucuronyltransferase / α-N-acetylglucosaminyltransferase (exostosin-2) (Ext2) 2.4.1.225 Bos taurus AAC35386.1
AAI26571.1
NP_803462.1		 O77783.1  
 ORF (protein for MGC:160120)   Bos taurus AAI50062.1 A6QR03  
 Ext2 (K01G5.6/Rib2)   Caenorhabditis elegans Bristol N2 AAC47510.1
AAW12599.1
BAB83878.1
CAB07245.1
NP_499368.1		 O01705.2  
 β-glucuronyltransferase / α-N-acetylglucosaminyltransferase (Ext1) 2.4.1.225 Cricetulus griseus AAF71276.1 Q9JK82  
 Ext2   Danio rerio AAV48783.1 Q5U7A7  
 exostosin-like 3 (Extl3)   Danio rerio AAI62406.1
AAV51343.1		 Q5U7D2  
 EXT1b   Danio rerio AAI25901.1
AAI65657.1
AAW29034.1		 Q5IGR7  
 EXT1c   Danio rerio AAI15217.1
AAI55813.1
AAW29035.1		 Q5IGR6  
 EXT1a   Danio rerio AAI33118.1
AAW29033.1		 Q5IGR8  
 Unknown (protein for MGC:153688) (OTTDARP00000010010)   Danio rerio AAI24427.1
CAP09235.1		 Q08C36  
 CG8433 (Dext2;sotv)   Drosophila melanogaster AAD38573.1
AAF58055.2
AAF58056.1
AAO39548.1
AAO41379.1
NP_725536.1
NP_788367.1
NP_788368.1		 A4UZJ2
Q9Y169		  
 tout-velu (CG10117;Dext1;ttv)   Drosophila melanogaster AAC32397.1
AAF58236.1
AAX33551.1
BAE78509.1
NP_477231.1		 Q5BI21
Q9V730
Q9V730.1		  
 heparan sulfate α-1,4-N-acetylglucosaminyltransferase-I/II (CG15110;Dext3;botv) 2.4.1.225 Drosophila melanogaster AAD34749.1
AAF57601.1
BAB89399.1
NP_523790.1		 Q9XZ08  
 RCJMB04_7p22 (fragment)   Gallus gallus CAH65209.1 Q5F3S5  
 unknown   Glycine max ACU19532.1 C6TCI0  
 unknown   Glycine max ACU20418.1 C6TF16  
 UDP-GlcUA:β-glucuronyltransferase / UDP-GlcNAc: α-N-acetylglucosaminyltransferase (exostosin-2;Ext2) 2.4.1.225 Homo sapiens AAB07008.1
AAB62718.1
AAC50764.1
AAC51219.1
AAH10058.1
AAH68545.1
NP_000392.1		 B2R5Z6
Q93063.1		  
 UDP-GlcUA:β-glucuronyltransferase / UDP-GlcNAc: α-N-acetylglucosaminyltransferase (exostosin-1;Ext1) 2.4.1.225 Homo sapiens AAB62283.1
AAH01174.1
ACS08204.1
BAG35949.1
NP_000118.1		 B2R7V2
Q16394.2		  
 exostosin-like 3 (Extl3;Extr1) 2.4.1.225 Homo sapiens AAB67602.1
AAC39598.1
AAD01877.1
AAD42041.1
AAH06363.1
AAP36017.1
AAW12588.1
AAW12594.1
ACW32787.1
BAA24080.1
BAA25445.2
BAG57702.1
NP_001431.1		 D3DST8
O43909.1
Q53XT3		  
 exostosin-like 1 (Extl1) 2.4.1.224 Homo sapiens AAC51141.1
AAD02840.1
AAF73172.1
AAH65528.1
AAW12597.1
CAI17130.1
NP_004446.1		 Q92935  
 UDP-GlcNAc: α-1,4-N-acetylglucosaminyltransferase (Exotosin-like 2) (Extl2;Extr2) 2.4.1.223 Homo sapiens AAC02898.1
AAH14910.1
AAH36015.1
AAH45681.1
AAR61360.1
AAW12598.1
BAA24081.1
BAC04893.1
BAG60404.1
NP_001430.1		 B2R795
D3DT60
Q8IYF4
Q8N8F1
Q9UBQ6		  
 unnamed protein product (fragment)   Macaca fascicularis BAE89111.1    
 MICPUN_70089 (fragment)   Micromonas sp. RCC299 ACO64184.1 C1E8N5  
 exostosin-2 (Ext2)   Mus musculus AAB17006.1
AAC53143.1
AAH06597.1
ABY16664.1
ACW41681.1
BAE22143.1
BAE28510.1
BAE29346.1
BAE31083.1
BAE37749.1
CAM22097.1
CAM22098.1
CAM23881.1
CAM23882.1
CAQ11719.1
NP_034293.1		 P70428.1  
 exostosin-1 (Ext1)   Mus musculus AAB41728.1
AAH04741.1
ABY16663.1
ACW41680.1
BAE21106.1
CAA65443.1
NP_034292.1		 P97464.1
Q3V1P4		  
 exostosin-like 1 (Extl1)   Mus musculus AAF61913.1
AAI20891.1
AAI20892.1
BAE36631.1
BAE43097.1
NP_062524.1		 Q0VAW4
Q9JKV7		  
 α-1,4-N-acetylglucosaminyltransferase-I/II / exostosin-like 3 (Extl3) 2.4.1.224 Mus musculus AAD42040.1
AAH65073.1
AAW12587.1
BAE23506.1
NP_061258.2		 Q9WVL6  
 α-N-acetylhexosaminyltransferase (Extl2) 2.4.1.- Mus musculus AAG17542.1
AAH31438.1
AAH94444.1
BAB31683.2
BAC26062.1
BAC27649.1
BAE34959.1
BAE36615.1
NP_067363.1		 Q8C089
Q8C197
Q9ES89.1		 1OMX[A,B]
1OMZ[A,B]
1ON6[A,B]
1ON8[A,B]
 exostoses 1, partial   Mustela putorius furo AER98199.1    
 exostoses 2   Mustela putorius furo AER98200.1    
 ORF   Mustela putorius furo AER98201.1    
 ORF (fragment)   Mustela putorius furo AER98203.1    
 Os05g0540000   Oryza sativa Japonica Group AAS79703.1
AAT58698.1
AAV59411.1
BAF18092.1		 Q53WK1  
 P0018H04.8   Oryza sativa Japonica Group BAD53800.1
BAH01223.1		 Q5Z8V4  
 Os03g0684500   Oryza sativa Japonica Group AAK14423.1
BAF12834.1		 Q10F19  
 OSTLU_41697   Ostreococcus lucimarinus CCE9901 ABO99406.1 A4S6M1  
 OSTLU_36758   Ostreococcus lucimarinus CCE9901 ABP01200.1 A4S6M1  
 Ot13g02070   Ostreococcus tauri OTTH0595 CAL56535.1 Q00WX6  
 unknown   Picea sitchensis ADE77623.1 D5ADK4  
 2_8443_01 (fragment)   Pinus lambertiana AEW08402.1    
 2_8443_01 (fragment)   Pinus radiata AEW08401.1    
 ORF (fragment)   Pipa carvalhoi AEQ16688.1    
 ORF (fragment)   Pipa carvalhoi AEQ17210.1    
 DKFZp459K2032   Pongo abelii CAH90611.1 Q5RC96  
 DKFZp468L2313   Pongo abelii CAH90937.1 Q5RBC3  
 Unknown (protein for IMAGE:7453681) (fragment)   Rattus norvegicus AAI05840.1 Q3B8R0  
 Reg receptor   Rattus norvegicus BAA92895.1
BAD90409.1
NP_064482.1		 Q9JMA8  
 Unknown protein for MGC:188484   Rattus norvegicus AAI66748.1 B2RYE4  
 Extl2 (MGC:187885;IMAGE:9091843)   Rattus norvegicus AAH91373.1
AAI62014.1		 B1WC59  
 ORF   Saccoglossus kowalevskii ACY92509.1 D1LX03  
 EXTL2   Salmo salar ACN11111.1 C0HAP2  
 Ext2 (fragment)   Salmo salar ACN58692.1 C0PUK1  
 SJCHGC08232 (fragment)   Schistosoma japonicum AAX26777.2 Q5C0P8  
 Smp_146320   Schistosoma mansoni CAZ32036.1
CAZ32037.1
CCD77273.1
CCD77274.1		 C4Q9B9  
 Smp_073220   Schistosoma mansoni CAZ34733.1
CCD75422.1		 C4QH01  
 Smp_172060   Schistosoma mansoni CAZ36393.1
CCD76297.1		 C4QLQ6  
 EXT1 (fragment)   Sus scrofa CAC67995.1 Q95KP6  
 VITISV_033101   Vitis vinifera CAN68561.1 A5C241  
 VITISV_017356 (fragment)   Vitis vinifera CAN79748.1 A5C7B3  
 VITISV_038958 (short fragment)   Vitis vinifera CAN76751.1 A5BDG3  
 Unknown (protein for MGC:89315)   Xenopus (Silurana) tropicalis AAH75481.1 Q6DIQ4  
 Unknown (protein for MGC:89702)   Xenopus (Silurana) tropicalis AAH80459.1
CAJ81810.1		 Q66KC7  
 Unknown (protein for MGC:79560)   Xenopus (Silurana) tropicalis AAH80918.1 Q66JH0  
 Unknown (protein for MGC:185216)   Xenopus (Silurana) tropicalis AAI66243.1 B2GUE4  
 XEXT1   Xenopus laevis AAH77234.1
AAH94398.1
BAB87180.1		 Q8QGX3  
 ORF   Xenopus laevis AAH44703.1
AAH60367.1		 Q7ZTM7  
 Unknown (protein for MGC:80258)   Xenopus laevis AAH72858.1 Q6GQ89  
 Unknown (protein for MGC:80904)   Xenopus laevis AAH73424.1 Q6GNS9  
 Unknown (protein for MGC:83950)   Xenopus laevis AAH81133.1
AAH94483.1		 Q66IZ2  
 exostosin   Xenopus laevis AAK15278.1
AAO84329.1		 Q98SV5  
 unknown   Zea mays ACG28807.1 B6SVC4  




Last update: 2012-01-31 © Copyright 1998-2012
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