| Activities in Family | Glucuronyl-galactosyl-proteoglycan 4-α-N-acetylglucosaminyltransferase (EC 2.4.1.223); Glucuronosyl-N-acetylglucosaminyl-proteoglycan α-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.224); |
|---|---|
| Mechanism | Retaining |
| 3D Structure Status | GT-A |
| Note | The long animal heparan synthases are made of two domains. The N-terminal domain, which adds b-1,4-GlcA residues, belongs to family GT47 while the C-terminal domain, which adds a-1,4-GlcNAc residues, belongs to family GT64. The plant homologs have a single domain. |
| External resources | Glymap; |
| Statistics | GenBank accession (757); Uniprot accession (31); PDB accession (20); 3D entries (4); cryst (0) |