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GlycosylTransferase Family 58

Known ActivitiesDol-P-Man: dolichol pyrophosphate-mannose α-1,3-mannosyltransferase (EC 2.4.1.130); Dol-P-Man: dolichol pyrophosphate-Man5GlcNAc2 α-1,2-mannosyltransferase (EC 2.4.1.130)
Mechanism Inverting
3D Structure StatusGT-C
NoteThese enzymes use dolichol-P-mannose as the sugar donor.
External resourcesInterPro; PFAM;
Statistics GenBank accession (121); Uniprot accession (40);
Summary
All (81) Eukaryota (81) Characterized (6)
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 ALNC14_099340 (Alnc14c207g8838)   Albugo laibachii Nc14 CCA23790.1    
 ORF   Amblyomma maculatum AEO36043.1    
 Dol-P-Man: α-1,3-mannosyltransferase (Alg3;At2g47760) 2.4.1.130 Arabidopsis thaliana AAC63631.1
AAL16193.1
AAP37662.1
AEC10883.1
AEC10884.1
AEC10885.1
NP_182297.1		 O82244
Q944H6		  
 ORF   Ascaris suum ADY43940.1    
 FAGOS_FAGL299C   Ashbya gossypii FDAG1 AEY98518.1    
 AN0104.2 (AlgC)   Aspergillus nidulans FGSC A4 EAA65282.1    
 An18g02360   Aspergillus niger CBS 513.88 CAK43166.1 A2RA94  
 AlgC (fragment)   Aspergillus niger FGSC A888 ABH09692.1 Q0MVR7  
 AO090120000319   Aspergillus oryzae RIB40 BAE62911.1    
 Unknown (protein for MGC:142824)   Bos taurus AAI23645.1 A4FV21  
 glycosyltransferase family 58 protein (Bofut4_p001860.1)   Botryotinia fuckeliana CCD52739.1    
 K09E4.2 (Alg3)   Caenorhabditis elegans Bristol N2 CAB70171.2
CBY25187.1
CBY25188.1
NP_496950.2		 E5QCI3
Q9NAP5		  
 CD36_64690   Candida dubliniensis CD36 CAX41333.1 B9WJB1  
 CAGL0A04587g   Candida glabrata CBS 138 CAG57860.1    
 CPAR2_601090   Candida parapsilosis CDC317 CCE39689.1    
 CGB_D2280C   Cryptococcus bacillisporus WM276 ADV21666.1    
 CNL04800   Cryptococcus neoformans var. neoformans JEC21 AAW46504.1    
 Unknown (protein for MGC:112396)   Danio rerio AAH95802.1
AAI64529.1		 Q501Z4  
 DEHA0A05984g   Debaryomyces hansenii CBS767 CAG84537.1    
 unknown   Dendroctonus ponderosae AEE63615.1    
 CG4084   Drosophila melanogaster AAF47050.1
ABC86276.1
ACQ89818.1
CAA54835.1
CAA64529.1
CAA64532.1
CAA64533.1
CAA64537.1
CAA64541.1
CAA66721.1
CAA71167.1
CAA71168.1
NP_523829.2		 Q27333.1  
 NOT58   Drosophila virilis CAA68963.1 Q24332  
 Ecym_7147   Eremothecium cymbalariae DBVPG#7215 AET40996.1    
 AGL299C   Eremothecium gossypii ATCC 10895 AAS54192.1
AAS54192.2		    
 unknown (fragment)   Glycine max ACU17920.1 C6T7W8  
 Dol-P-Man: dolichol pyrophosphate-Man5GlcNAc2 α-1,2-mannosyltransferase (Alg3;NOT;NOT56L) 2.4.1.130 Homo sapiens AAH02839.1
AAH04313.1
BAF82050.1
BAG60059.1
BAG61512.1
CAA70220.1
NP_005778.1		 Q92685.1  
 predicted protein   Hordeum vulgare subsp. vulgare BAJ88828.1    
 ORF (fragment)   Hymenochirus curtipes AEQ18192.1    
 KAFR_0L01850 (Kafr0l01850)   Kazachstania africana CBS 2517 type strain:CBS 2517 CCF60795.1    
 KLLA0E20823g   Kluyveromyces lactis NRRL Y-1140 CAG99975.1    
 Dol-P-Man: Man5GlcNAc2-PP-Dol α-1,3-mannosyltransferase (Alg3) 2.4.1.130 Komagataella pastoris AAT72073.1 Q6DNA2  
 KLTH0C06314g   Lachancea thermotolerans CBS 6340 CAR22062.1    
 LbrM35_V2.2270 (probable fragment)   Leishmania braziliensis CAM43979.1 A4HP72  
 LDBPK_362160   Leishmania donovani BPK282A1 CBZ38654.1    
 LinJ36.4580 (possible fragment)   Leishmania infantum JPCM5 (MCAN/ES/98/LLM-877) CAM72908.1    
 LmjF36.2040 (probable fragment)   Leishmania major strain Friedlin CAJ09161.1 Q4Q1L8  
 LMXM_36_2040   Leishmania mexicana MHOM/GT/2001/U1103 CBZ26054.1    
 ORF   Leptosphaeria maculans v23.1.3 CBX89957.1 E4ZQ47  
 MG08010.4   Magnaporthe grisea 70-15 XP_362427.1
XP_362427.2		    
 MICPUN_68602 (fragment)   Micromonas sp. RCC299 ACO63494.1 C1E6U6  
 GNLVRS01_PISO0D04271g (Piso0_000794)   Millerozyma farinosa CBS 7064 CCE78765.1    
 GNLVRS01_PISO0C04160g (Piso0_000794)   Millerozyma farinosa CBS 7064 CCE78177.1    
 ORF   Mus musculus AAH31893.1
NP_666051.1		 Q8K2A8  
 ORF (fragment)   Mustela putorius furo AER94048.1    
 ORF (fragment)   Mustela putorius furo AER94049.1    
 MYCTH_2310419   Myceliophthora thermophila ATCC 42464 AEO60805.1    
 NCAS_0E02510   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC70321.1    
 NDAI_0E04080   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD25225.1    
 NCU06552.1 (G6G8.10)   Neurospora crassa OR74A AAK07848.1
XP_326407.1		 Q9C1K8  
 P0583G08.18   Oryza sativa Japonica Group BAB64783.1
BAG90895.1		    
 OSTLU_47741   Ostreococcus lucimarinus CCE9901 ABP00161.1 A4S939  
 Ot17g01180   Ostreococcus tauri OTTH0595 CAL57845.1 Q00TH1  
 Pc21g07120   Penicillium chrysogenum Wisconsin 54-1255 CAP95609.1 B6HK35  
 Dol-P-Man dependent α-1,3-mannosyltransferase (Alg3)   Pichia angusta DL1 ABB04524.1 A0RZJ0  
 PP7435_Chr4-0251 (Rhk1)   Pichia pastoris CBS 7435 CCA40426.1    
 PAS_chr4_0712   Pichia pastoris GS115 CAY71973.1 Q6DNA2  
 PICST_58095   Pichia stipitis CBS 6054 ABN66377.1
ABN66377.2		    
 PIIN_03303   Piriformospora indica CCA69403.1    
 unnamed protein product   Podospora anserina S mat+ CAP65337.1 B2AMZ6  
 unknown (WS0122_J10)   Populus trichocarpa ABK95338.1 A9PG35  
 ORF (possible fragment)   Rattus norvegicus AAH88475.1 Q5M7T0  
 EC1118_1B15_0309g   Saccharomyces cerevisiae EC1118 Lalvin EC1118 CAY77702.1 C8Z3R2  
 Dol-P-Man: Man5GlcNAc2-PP-Dol α-1,3-mannosyltransferase (Alg3;Rhk1;YBL082c;YBL0720) 2.4.1.130 Saccharomyces cerevisiae S288c AAA75352.1
CAA56024.1
CAA84904.1
NP_009471.1		 P38179  
 Alg3   Salmo salar ACN10443.1 C0H8S4  
 ORF (fragment)   Schistosoma japonicum AAW26517.1 Q5DCD9  
 ORF (fragment)   Schistosoma japonicum AAW26291.1 Q5DD15  
 Smp_150200   Schistosoma mansoni CAZ32774.1 C4QBD9  
 Dol-P-Man: Man5GlcNAc2-PP-Dol α-1,3-mannosyltransferase (Alg3;Cps11;SPAC7D4.06C) 2.4.1.130 Schizosaccharomyces pombe 972h- CAB16723.2
NP_593853.1		 Q9Y7I4  
 sr11327   Sporisorium reilianum SRZ2 CBQ71473.1    
 TPHA_0K00760   Tetrapisispora phaffii CBS 4417 type strain:CBS 4417 CCE65210.1    
 THITE_32842   Thielavia terrestris NRRL 8126 AEO66311.1    
 TDEL_0C02670 (Tdel0c02670)   Torulaspora delbrueckii type strain:CBS 1146 CCE91156.1    
 Dol-P-Man: Man5GlcNAc2-PP-Dol α-1-3-mannosyltransferase (Alg3) 2.4.1.130 Trypanosoma brucei brucei 427 CAO98979.1 A8E112  
 TbgDal_X7980   Trypanosoma brucei gambiense DAL972 Dal 927 clone 1 (MHOM/CI/86/DAL972) CBH15709.1 D0A365  
 TCIL3000_10_5600   Trypanosoma congolense IL3000 CCC93794.1    
 Unknown (protein for MGC:181324)   Xenopus (Silurana) tropicalis AAI54934.1 A8WH14  
 Unknown (protein for IMAGE:8463180)   Xenopus laevis AAI28939.1
AAI55872.1
AAI70387.1		 A9JS09  
 YALI0E03190g   Yarrowia lipolytica CLIB122 CLIB99 CAG79067.1    
 unknown   Zea mays ACG36193.1 B6TGG0  
 unknown (ZM_BFc0039G19)   Zea mays B73 ACF84701.1 B4FRF8  
 ZYRO0B03696g   Zygosaccharomyces rouxii CBS 732 CAR26183.1    




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