GlycosylTransferase Family 51

Activities in Familymurein polymerase (EC 2.4.1.129).
Mechanism Inverting
3D Structure Statuslysozyme-type
Catalytic Nucleophile/BaseGlu
NoteThere are two categories of enzymes in this family : monofunctional (just the GT51 module) or bifunctional (GT51 module attached to a penicillin-binding transpeptidase module). These enzymes utilise Und-PP-MurAc-(GlcNAc)-pentapeptide as the sugar donor.
Statistics GenBank accession (40513); Uniprot accession (3452); PDB accession (31); 3D entries (8); cryst (0)
All (39031) Archaea (2) Bacteria (38926) Eukaryota (10) unclassified (93) Structure (8) Characterized (15)
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 RIEGSTA812A_PEG_1134   invertebrate metagenome VBB69661.1    
 ArsC (fragment)   uncultured organism AFH58703.1    
 ArsC (fragment)   uncultured organism AFH58704.1    
 EKD16_00710 (Pbpf1)   Streptomonospora sp. M2 QBI51962.1    
 EKD16_01125 (Pbpf2)   Streptomonospora sp. M2 QBI52042.1    
 EKD16_05535 (Pona1)   Streptomonospora sp. M2 QBI52910.1    
 EKD16_24905 (Pona2)   Streptomonospora sp. M2 QBI56722.1    
 WN16_01780   Citrobacter sp. ABFQG QBI27993.1    
 WN16_07875 (MrcB)   Citrobacter sp. ABFQG QBI29089.1    
 WN16_00775   Citrobacter sp. ABFQG QBI27817.1    
 WN16_21350   Citrobacter sp. ABFQG QBI31510.1    
 ERC79_14195   Rhodococcus sp. ABRD24 QBJ98725.1    
 ERC79_10970   Rhodococcus sp. ABRD24 QBJ98665.1    
 ERC79_11070   Rhodococcus sp. ABRD24 QBJ96437.1    
 ERC79_11045   Rhodococcus sp. ABRD24 QBJ96433.1    
 E0Z06_03710 (MrcB)   Rheinheimera sp. D18 QBL10866.1    
 E0Z06_11920   Rheinheimera sp. D18 QBL10175.1    
 E0Z06_05960 (PbpC)   Rheinheimera sp. D18 QBL09087.1    
 MG068_16715   Stenotrophomonas sp. ASS1 QBL42069.1    
 MG068_15595 (PbpC)   Stenotrophomonas sp. ASS1 QBL41862.1    
 MG068_15970 (MrcB)   Stenotrophomonas sp. ASS1 QBL41931.1    
 MG068_15780   Stenotrophomonas sp. ASS1 QBL41896.1    
 MARI_23560 (MrcB)   Marinobacter sp. JH2 QBM18217.1    
 MARI_22320 (MrcA)   Marinobacter sp. JH2 QBM18103.1    
 MARI_01770 (MtgA)   Marinobacter sp. JH2 QBM16097.1    
 E1B03_23550 (MtgA)   Citrobacter sp. LY-1 QBM25248.1    
 E1B03_19560 (PbpC)   Citrobacter sp. LY-1 QBM24512.1    
 E1B03_05255 (MrcB)   Citrobacter sp. LY-1 QBM21867.1    
 E1B03_24460 (MrcA)   Citrobacter sp. LY-1 QBM25411.1    
 E1750_10650   Flavobacterium sp. GS13 QBN19242.1    
 E1750_10230   Flavobacterium sp. GS13 QBN19161.1    
 E1750_09835 (MtgA)   Flavobacterium sp. GS13 QBN19087.1    
 NBC122_02261 (MtgA)   Chryseobacterium sp. NBC122 QBO59066.1    
 NBC122_00820 (MrcA)   Chryseobacterium sp. NBC122 QBO57655.1    
 EYD13_21780 (Pona2)   Saccharomonospora sp. 31sw QBQ62683.1    
 EYD13_20085 (Pona1)   Saccharomonospora sp. 31sw QBQ62354.1    
 E1956_11025   Paraburkholderia sp. 7MH5 QBQ97657.1    
 E1956_24070   Paraburkholderia sp. 7MH5 QBR00814.1    
 W01_00670 (MtgA)   Candidatus Nitrotoga sp. AM1 BBJ22140.1    
 E1956_04510   Paraburkholderia sp. 7MH5 QBQ96506.1    
 E1956_05385 (MtgA)   Paraburkholderia sp. 7MH5 QBQ96663.1    
 E1956_37865   Paraburkholderia sp. 7MH5 QBR02963.1    
 E3D81_08340 (MtgA)   Sphingobacterium sp. CZ-2 QBR12169.1    
 E3D81_14855   Sphingobacterium sp. CZ-2 QBR13382.1    
 E3D81_09455   Sphingobacterium sp. CZ-2 QBR12372.1    
 E3D81_12365   Sphingobacterium sp. CZ-2 QBR12910.1    
 E3Z29_00375 (MtgA)   Pseudomonas sp. S150 QBR29099.1    
 E3Z29_04635   Pseudomonas sp. S150 QBR29876.1    
 W01_16150   Candidatus Nitrotoga sp. AM1 BBJ23688.1    
 E3Z29_26885 (MrcB)   Pseudomonas sp. S150 QBR33886.1    
 E2F51_11335 (MrcB)   Erwinia sp. QL-Z3 QBR50535.1    
 KTC_53710   Thermosporothrix sp. COM3 BBH90620.1    
 KTC_09340   Thermosporothrix sp. COM3 BBH86183.1    
 KTC_47230   Thermosporothrix sp. COM3 BBH89972.1    
 KTC_46300   Thermosporothrix sp. COM3 BBH89879.1    
 KTC_47220   Thermosporothrix sp. COM3 BBH89971.1    
 DAIF1_31820 (MtgA)   Stenotrophomonas sp. DAIF1 QBR45598.1    
 E2F51_05320 (MrcA)   Erwinia sp. QL-Z3 QBR49450.1    
 DAIF1_33700 (MrcA)   Stenotrophomonas sp. DAIF1 QBR45783.1    
 E2F51_04550 (MtgA)   Erwinia sp. QL-Z3 QBR49305.1    
 DAIF1_32260 (MrcB)   Stenotrophomonas sp. DAIF1 QBR45642.1    
 E2F51_01375 (PbpC)   Erwinia sp. QL-Z3 QBR48729.1    
 DAIF1_31460 (PbpC)   Stenotrophomonas sp. DAIF1 QBR45562.1    
 penicillin-insensitive transglycosylase & transpeptidase   unidentified QBQ71818.1    
 E4K62_13485   Microbacterium sp. dk512 QBR89597.1    
 E4K62_15945   Microbacterium sp. dk512 QBR90044.1    
 E1B22_03495   Thermaerobacter sp. FW80 QBS38450.1    
 E4191_02010   Paracoccus sp. 2251 QBX33630.1    
 E4191_08235   Paracoccus sp. 2251 QBX34698.1    
 E4191_14415 (MtgA)   Paracoccus sp. 2251 QBX35749.1    
 E4Z61_18640 (MrcA)   Citrobacter sp. SNU WT2 QBX82265.1    
 E4Z61_12810 (MrcB)   Citrobacter sp. SNU WT2 QBX81194.1    
 E4Z61_23240 (PbpC)   Citrobacter sp. SNU WT2 QBX83104.1    
 E4Z61_19490 (MtgA)   Citrobacter sp. SNU WT2 QBX82422.1    
 E1B22_07850   Thermaerobacter sp. FW80 QBS37706.1    
 E4M01_14180 (MtgA)   Brevundimonas sp. MF30-B QBX38812.1    
 E4M01_12420   Brevundimonas sp. MF30-B QBX38488.1    
 E4M01_03090   Brevundimonas sp. MF30-B QBX36827.1    
 E2K80_09855   Boseongicola sp. CCM32 QBY00995.1    
 E2K80_15475 (PbpC)   Boseongicola sp. CCM32 QBY02815.1    
 E2K93_09855   Thalassotalea sp. HSM 34 QBY06186.1    
 E2K80_12690   Boseongicola sp. CCM32 QBY01474.1    
 E2K80_15535 (MtgA)   Boseongicola sp. CCM32 QBY01963.1    
 E2K80_16515   Boseongicola sp. CCM32 QBY02142.1    
 E2K93_10255 (MrcB)   Thalassotalea sp. HSM 34 QBY04744.1    
 EPZ47_02030   Pseudomonas sp. 11K1 QBZ87538.1    
 EPZ47_28105   Pseudomonas sp. 11K1 QBZ92389.1    
 EPZ47_25150 (MrcB)   Pseudomonas sp. 11K1 QBZ91841.1    
 E4Z98_04300   unidentified QCA28572.1    
 E4Z98_06865   unidentified QCA29047.1    
 E4Z98_04630   unidentified QCA28637.1    
 Sequence 113 from patent US 7026463   unidentified ABH65254.1
ABL21130.1
   
 BUCNMO_163 (MrcB)   Buchnera aphidicola (Nipponaphis monzeni) Nmo BBI01178.1    
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