GlycosylTransferase Family 47

Activities in Familyheparan β-glucuronyltransferase (EC 2.4.1.225); xyloglucan β-galactosyltransferase (EC 2.4.1.-); heparan synthase (EC 2.4.1.-); arabinan α-L-arabinosyltransferase (EC 2.4.2.-).
Mechanism Inverting
NoteThe long animal heparan synthases are made of two domains. The N-terminal domain, which adds b-1,4-GlcA residues, belongs to family GT47 while the C-terminal domain, which adds a-1,4-GlcNAc residues, belongs to family GT64. The plant homologs, which have a single domain, display various specificities ranging from xyloglucan b-galactosyltransferase to a pectin b-glucuronyltransferase and arabinan a-L-arabinosyltransferase.
External resourcesGlymap;
Statistics GenBank accession (1008); Uniprot accession (236);
All (462) Bacteria (3) Eukaryota (457) Viruses (2) Characterized (13)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 MuYL_4915   Mucilaginibacter sp. BJC16-A31 ASU36798.1    
 Synpcc7942_0047   Synechococcus elongatus PCC 7942 ABB56079.1    
 M744_02865   Synechococcus sp. UTEX 2973 AJD56859.1    
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