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GlycosylTransferase Family 29

Activities in FamilyUDP-Gal: β-1,3-galactan β-1,6-galactosyltransferase (EC 2.4.1.-);
UDP-Gal: β-1,6-galactan β-1,6-galactosyltransferase (EC 2.4.1.-);
CMP-NeuAc: α-2,8-polysialyltransferase (EC 2.4.3.-);
Sialyltransferase (EC 2.4.3.-);
CMP-NeuAc: β-galactoside α-2,6-sialyltransferase (EC 2.4.3.1);
CMP-Neu5Ac: α-N-acetylgalactoside α-2,6-sialyltransferase (EC 2.4.3.3);
CMP-Neu5Ac: β-galactoside α-2,3-sialyltransferase (EC 2.4.3.4);
CMP-Neu5Ac: N-acetyllactoside α-2,3-sialyltransferase (EC 2.4.3.6);
α-N-acetylneuraminyl-2,3-β-galactosyl-1,3-N-acetylgalactoside α-2,6-sialyltransferase (EC 2.4.3.7);
CMP-Neu5Ac : α-N-acetylneuraminate α-2,8-sialyltransferase (EC 2.4.3.8);
Lactosylceramide α-2,3-sialyltransferase (EC 2.4.3.9);
Transferring other glycosyl groups (EC 2.4.99.-);
Mechanism Inverting
NoteThese enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resourcesCFG(Core1); CFG(Glycosphingolipid); CFG(N-linked); CFG(Terminal); Glymap;
Statistics GenBank accession (2061); Uniprot accession (180); PDB accession (16); 3D entries (6); cryst (0)
Summary
Download GT29 (1287) Taxonomic display Structure (6) Characterized (56)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 12 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 α-2,8-sialyltransferase (SIAT8C)   Gallus gallus CAG27882.1    
 α-2,8-sialyltransferase (SIAT8B)   Gallus gallus CAG27881.1    
 α-2,8-syalyltransferase ST8Siα-V (SIAT8C)   Gallus gallus CAG28697.1    
 α-2,3-sialyltransferase ST3Gal IV (Siat4c)   Gallus gallus CAI29182.1
AFN40450.1		    
 α-2,3-sialyltransferase ST3Gal III (Siat6)   Gallus gallus CAI26252.1
AFK24468.1		    
 ST3 β-galactoside α-2,3-sialyltransferase 1 (St3gal1)   Gallus gallus AFN40455.1    
 ST6 β-galactosamide α-2,6-sialyltransferase 1 (St6gal1)   Gallus gallus AFN40452.1    
 ST3 β-galactoside α-2,3-sialyltransferase 6 (St3gal6)   Gallus gallus AFN40454.1    
 ST3 β-galactoside α-2,3-sialyltransferase 3 (St3gal3)   Gallus gallus AFN40456.1    
 ST6Gal I   Gasterosteus aculeatus CBQ74103.1    
 ST6Gal II   Gasterosteus aculeatus CBQ74104.1    
 α-2,8-sialyltransferase ST8Sia VI (siat 8F)   Gasterosteus aculeatus CAL91581.1    
 α-2,8-sialyltransferase ST8Sia V (siat 8E)   Gasterosteus aculeatus CAM12264.1    
 α-2,8-sialyltransferase II (ST8Sia II;SiaT8b)   Gasterosteus aculeatus CAM12268.1    
 α-2,8-sialyltransferase ST8Sia IIIA (siat 8C)   Gasterosteus aculeatus CAM12269.1    
 α-2,8-sialyltransferase ST8Sia IIIB (siat 8Cr)   Gasterosteus aculeatus CAM12270.1    
 α-2,8-sialyltransferase ST8Sia I (siat 8A)   Gasterosteus aculeatus CAM12271.1    
 Stv2A   Glycine max CAJ15143.1    
 Stv2B   Glycine max CAJ15144.1
ACU19810.1		    
 Stv1   Gossypium raimondii CAJ15145.1    
 147787   Guillardia theta CCMP2712 (Guith1)      
 145289   Guillardia theta CCMP2712 (Guith1)      
 133129   Guillardia theta CCMP2712 (Guith1)      
 ST6GALNAC2   Gulo gulo luscus WGG27377.1    
 sialyltransferase 4 (St4)   Hemicentrotus pulcherrimus BAI77454.1    
 sialyltransferase 5 (St5)   Hemicentrotus pulcherrimus BAI77455.1    
 sialyltransferase 3 (St3)   Hemicentrotus pulcherrimus BAI77453.1    
 sialyltransferase 7 (St7) (partial)   Hemicentrotus pulcherrimus BAJ10551.1    
 sialyltransferase 8 (St8)   Hemicentrotus pulcherrimus BAM36888.1    
 HERILL_LOCUS1276   Hermetia illucens CAD7077980.1    
 α-2,3-sialyltransferase I (ST3Gal I;Siat4A) 2.4.3.4 Homo sapiens AAG29876.1
AAA36612.1
AAC17874.1
AAC37574.1
AAD39238.1
AAH18357.1
CAS91688.1
NP_003024.1
NP_775479.1		 A0A024R9L6
Q11201		  
 α-2,3-sialyltransferase III (ST3Gal III;SiaT6) 2.4.3.6 Homo sapiens CAF25177.1
AAA35778.1
AAH50380.1
AAO13859.1
AAO13861.1
AAO13862.1
AAO13863.1
AAO13864.1
AAO13866.1
AAO13867.1
AAO13869.1
AAO13870.1
AAO13871.1
AAO13872.1
AAO13874.1
AAO38807.1
AAO38808.1
AAO38809.1
AAO38810.1
AAO38811.1
ANZ79617.1
BAG63274.1
CAH71022.1
CAH71023.1
CAH71024.1
CAH71027.1
CAH71028.1
CAH71029.1
CAH71030.1
CAH71031.1
CAH71032.1
CAH71033.1
CAI16785.1
CAI16786.1
CAI16787.1
CAI16790.1
CAI16791.1
CAI16792.1
CAI16793.1
CAI16794.1
CAI16795.1
CAI16796.1
CAI22181.1
CAI22182.1
CAI22183.1
CAI22186.1
CAI22187.1
CAI22188.1
CAI22189.1
CAI22190.1
CAI22191.1
CAI22192.1
CAS91690.1
CAT03463.1
NP_006270.1
NP_777624.1
NP_777626.1
NP_777629.1
NP_777632.1		 A0A1B2JLU4
D3DPX8
P61132
Q11203
Q11203
Q5T4X0		  
 α-2,3-sialyltransferase IV (ST3Gal IV;ST3GAL4;Siat4c;STZ) 2.4.3.4 Homo sapiens AAH10645.1
AAA16460.1
AAC14162.1
AAK93790.1
AAM66431.1
AAM66432.1
AAM66433.1
AAM81378.1
ACM84702.1
BAB13940.1
BAF84266.1
BAG37279.1
CAA52662.1
CAE91353.1
CAG33139.1
CAS91691.1
NP_006269.1		 Q11206
Q6IBE6
Q8N6A6
Q8N6A7
Q8NFD3
Q8NFG7
Q9HAA9		  
 α-2,3-sialyltransferase II (ST3Gal II;Siat4B;Siat5) 2.4.3.4 Homo sapiens AAH36777.1
AAB40389.1
BAG35855.1
BAG54481.1
CAA65447.1
CAS91689.1
NP_008858.1		 A0A024QZA4
B2R7K8
B3KXG9
Q16842		  
 α-2,3-sialyltransferase VI (ST3GalVI;St3Gal6;Siat10) (St3gal6) 2.4.3.4 Homo sapiens AAD39131.1
AAH23312.1
BAA77609.1
BAG50993.1
CAE89895.1
CAF00161.1
CAS91693.1
NP_006091.1		 B2RCH2
D3DN39
Q9Y274		  
 α-2,8-polysialyltransferase IV (ST8Sia IV;Siat8d;PST-1) 2.4.3.- Homo sapiens AAH53657.1
AAC41775.1
AAH27866.1
ACM85043.1
BAF85561.1
CAN37586.1
CAS91698.1
NP_005659.1		 A8KA07
Q8N1F4
Q92187		 6AHZ[A]
 α-2,8-sialyltransferase V (ST8SiaV;Siat8e;SAT-V) (St8sia5)   Homo sapiens AAC51727.1
AAI08911.1
BAG51661.1
BAG52854.1
BAH11545.1
BAH12893.1
CAG33318.1
CAS91699.1
NP_037437.1		 B3KSU2
B7Z5F7
O15466		  
 α-2,8-sialyltransferase III (ST8Sia III;Siat8c)   Homo sapiens AAB87642.1
AAC15901.2
AAH74909.1
BAD92233.1
BAF82206.1
BAG35879.1
CAS91697.1
NP_056963.1		 A8K0F2
O43173
Q59GW3		 5BO6[A,B]
5BO7[A,B]
5BO8[A,B]
5BO9[A,B]
5CXY[A,B]
 α-2,8-sialyltransferase I (ST8Sia I;Siat8a;SAT-II;GD3 synthase) 2.4.3.8 Homo sapiens AAC37586.1
AAA62366.1
AAH31081.1
AAI17286.1
AAI26163.1
AAQ53140.1
ABN29101.1
ACM80809.1
ACM82503.1
BAA05391.1
BAF83630.1
BAG59776.1
CAA54891.1
CAS91695.1
NP_003025.1		 A8K4H6
B4DM64
Q92185		  
 α-2,8-sialyltransferase II (ST8Sia II;St8Sia2;SiatbB;STX)   Homo sapiens AAC24458.1
AAA36613.1
AAB51242.1
AAH69584.1
AAH96202.1
AAH96203.1
AAH96204.1
AAH96205.1
ACM83967.1
ACS13735.1
ACS13736.1
CAS91696.1
NP_006002.1		 B2R9U8
C6G488
Q4VAY9
Q4VAZ2
Q92186		  
 CMP-NeuAc: β-galactoside α-2,6-sialyltransferase I (ST6GAL1;ST6Gal I;Siat1;Siat-1;ST6N) 2.4.3.1 Homo sapiens CAA01327.1
AAH31476.1
AAH40009.1
ACM80808.1
ACM85639.1
ACQ18409.1
BAF85568.1
BAG34960.1
CAA01686.1
CAA35111.1
CAA38246.1
CAA44634.1
CAS91678.1
NP_003023.1
NP_775323.1		 A8KA14
D3DNV3
P15907		 4JS1[A]
4JS2[A]
6QVS[A,B]
6QVT[A,B]
 lactosylceramide α-2,3-sialyltransferase V (ST3Gal V;Siat9) 2.4.3.9 Homo sapiens AAD14634.1
AAF66146.1
AAH65936.2
AAO16866.1
AAO16866.2
AAP65066.1
AAQ89463.1
AAY24147.1
ABI12336.1
ABX94074.1
ABX96367.1
ABX96677.1
ABY05141.1
ABY16080.1
ABY18877.1
ACC23222.1
ACE08868.1
ACG89779.1
ACK00075.1
ACM84564.1
ACM95185.1
ACP58739.1
ACP73940.1
ACP88674.1
ACS06566.1
ACW23933.1
ALQ33905.1
ALQ33906.1
BAA33950.1
BAG50894.1
CAE89320.1
CAJ44921.1
CAS91692.1
NP_003887.2		 A0A0S2Z4Q7
A0A0S2Z4S6
B3KM82
Q9UNP4		  
 CMP-NeuAc:N-acetylgalactosaminide α-2,6-sialyltransferase II (ST6GalNAc II;Sia7b;SThM) 2.4.3.3 Homo sapiens AAH40455.1
AAA52228.1
AAV38775.1
CAB61434.1
CAS91683.1
NP_006447.1		 A0A024R8M1
Q9UJ37		 6APJ[A,B,C,D,E,F]
6APL[A,B,C,D,E,F]
 N-acetylgalactosaminide α-2,6-sialyltransferase VI (ST6GalNAc VI;St6GalNAc6)   Homo sapiens AAH06564.1
AAH07802.1
AAH16299.1
AAH36102.1
AAQ89035.1
ABA31389.1
ABA36389.1
ABA37971.1
ABA68648.1
ABA69651.1
ABA70033.1
ABA70156.1
ABC03977.1
ABC16012.1
ABE23467.1
ABE26030.1
ABE26303.1
ABH64540.1
ABH64663.1
ABH64820.1
ABH66049.1
ABH70868.1
ABH70991.1
ABH72505.1
ABH75620.1
ABH99405.1
ABI02510.1
ABI07311.1
ABI10959.1
ABI12183.1
ABJ19344.1
ABJ34339.1
ABL21803.1
ABX93921.1
ABX96214.1
ABX96524.1
ABY04988.1
ABY15927.1
ABY18724.1
ACC22759.1
ACC35829.1
ACE08715.1
ACG89626.1
ACJ99921.1
ACM95032.1
ACN08791.1
ACP73787.1
ACS06413.1
ACS08565.1
ACW23780.1
ADO22440.1
ALQ34075.1
ALQ34076.1
BAA87035.1
BAB14715.1
BAG51863.1
BAG62242.1
CAD45373.1
CAE91145.1
CAG33599.1
CAI12609.1
CAI12610.1
CAI12611.1
CAI12612.1
CAS91687.1
NP_038471.2		 A0A0S2Z5G9
A0A0S2Z653
B4DU80
Q969X2
Q9H8A2		  
 N-acetylgalactosaminide α-2,6-sialyltransferase IV (ST6GalNAcIV;Siat7d;Siat3c) (St6galnac4) 2.4.3.7 Homo sapiens BAA87034.1
AAF00102.1
AAH36705.1
AAP63349.1
ACG89841.1
ACH33352.1
BAA91281.1
BAF84738.1
CAB44353.1
CAB44354.1
CAC07404.1
CAC24981.1
CAC27250.1
CAF14360.1
CAI12613.1
CAS91685.1
CAX11911.1
NP_055218.3
NP_778204.1		 A0A024R881
A8K7N4
Q5T9D0
Q9H4F1		  
 N-acetylgalactosaminide α-2,6-sialyltransferase V (St6alNAc5;ST6GalNAcV;Siat7e)   Homo sapiens AAH01201.1
ABE14908.1
AHA82580.1
BAB71127.1
BAG53123.1
BAG58078.1
CAB72344.1
CAD45372.1
CAI21821.1
CAM28274.1
CAS91686.1
EAX06386.1
NP_112227.1		    
 N-acetylgalactosaminide α-2,6-sialyltransferase I (Siat7A;Sia7a;ST6GALNAC1;ST6GalNAc I) 2.4.3.3 Homo sapiens CAA72179.2
AAH22462.1
AAM22800.1
AAQ89277.1
ABA13600.1
ABA33477.1
ABC03856.1
ABC04774.1
ABC15951.1
ABE24539.1
ABE25352.1
ABH65894.1
ABH72000.1
ABH72444.1
ABH72821.1
ABH75559.1
ABH83062.1
ABH93236.1
ABH98460.1
ABI01924.1
ABI02448.1
ABI11364.1
ABI12733.1
ABJ18775.1
ABJ30959.1
ABJ35147.1
ABJ39089.1
ABJ41693.1
ABL13582.1
ABN30350.1
ABX91728.1
ABX92004.1
ABX92280.1
ABX92556.1
ABX92832.1
ABX93266.1
ABX93773.1
ABX94507.1
ABX95514.1
ABX95790.1
ABX96066.1
ABY04288.1
ABY04564.1
ABY04840.1
ABY16532.1
ABY18024.1
ABY18300.1
ABY18576.1
ACC00203.1
ACC25401.1
ACC26418.1
ACC36990.1
ACE07635.1
ACE09473.1
ACE10685.1
ACG89184.1
ACJ96248.1
ACN02514.1
ACN06924.1
ACP58316.1
ACP73639.1
ACP89167.1
ACR89117.1
ACR89669.1
ACW28759.1
BAA90953.1
CAS91682.1
NP_060884.1		 Q8TBJ6
Q9NSC7		  
 α-2,6-sialyltransferase 2 (ST6GAL2;ST6Gal II;KIAA1877) 2.4.3.1 Homo sapiens BAB47506.1
AAH08680.1
AAY15022.1
BAB47506.2
BAC24793.1
CAD54408.1
CAE48260.1
CAE48261.1
CAS91680.1
NP_115917.1		 D3DVK3
Q86Y44
Q96HE4
Q96JF0		  
 α-2,8-sialyltransferase VI (ST8SIA VI)   Homo sapiens CAF21722.1
AAI37103.1
AAI37104.1
ACA06074.1
ACA06075.1
ACA06076.1
BAE94653.1
CAH70722.1
CAI40658.1
CAI40659.1
CAS91700.1
NP_001004470.1
XP_291725.3		    
 N-acetylgalactosaminide α-2,6-sialyltransferase III (ST6GalNAc III;Sia7c) 2.4.3.7 Homo sapiens CAD45371.1
AAH59363.1
AAQ88904.1
ABA66708.1
ABI12351.1
ABX96382.1
ABX96692.1
ABY05156.1
ABY16095.1
ABY18892.1
ACC23237.1
ACC35997.1
ACC36307.1
ACE08883.1
ACH32638.1
ACK00090.1
ACM95200.1
ACP73955.1
ACS06581.1
ACW23948.1
BAC03611.1
BAG59810.1
CAK32360.1
CAS91684.1
NP_694541.1		 B4DM98
Q8NDV1
Q8NDV1		  
 Stv3   Hordeum vulgare CAJ15146.1    
 predicted protein   Hordeum vulgare subsp. vulgare BAK05762.1    
 ORF (fragment)   Hymenochirus curtipes AEQ17925.1    
 Sia7E   Ictalurus punctatus ADO28996.1    
 ORF (St6galnac3)   Ictalurus punctatus AHH40167.1    
 ORF (St8sia4)   Ictalurus punctatus AHH37676.1    
 ORF (St6gal2)   Ictalurus punctatus AHH37986.1    
 ORF (St6galnac3)   Ictalurus punctatus AHH38248.1    
 ORF (St3gal5)   Ictalurus punctatus AHH39684.1    
 ORF (St8sia1)   Ictalurus punctatus AHH40000.1    
 ORF (St8sia3)   Ictalurus punctatus AHH40132.1    
 ORF (St8sia5)   Ictalurus punctatus AHH40334.1    
 ORF (St3gal3)   Ictalurus punctatus AHH42788.1    
 IPOD504_ LOCUS 14409   Iphiclides podalirius CAH2068551.1    
 ST6Gal (fragment)   Ixodes scapularis ADO17789.1    
 LSAL_LOCUS8804 (fragment)   Lactuca saligna CAB4080281.1    
 LSAL_LOCUS23298   Lactuca saligna CAB4095626.1    
 LSAL_LOCUS29097 (fragment)   Lactuca saligna CAB4101784.1    
 LSALG_LOCUS8804 (fragment)   Lactuca saligna CAI9268375.1    
 LATHSAT_LOCUS11547   Lathyrus sativus CAK8542736.1    
 LATHSAT_LOCUS31077   Lathyrus sativus CAK8579109.1    
 LSAA_14924 (fragment)   Lepeophtheirus salmonis IoA-00 CAF3036992.1
CAB4069938.1		    
 LSAA_15025   Lepeophtheirus salmonis IoA-00 CAF3034191.1
CAB4069772.1		    
 LSAA_14950   Lepeophtheirus salmonis IoA-00 CAF3036246.1
CAB4069894.1		    
 LSAA_11385 (fragment)   Lepeophtheirus salmonis IoA-00 CAF2982562.1
CAB4067137.1		    
 LSAA_14642   Lepeophtheirus salmonis IoA-00 CAF3034209.1
CAB4069773.1		    
 LSAA_4046   Lepeophtheirus salmonis IoA-00 CAF2833408.1
CAB4058496.1		    
 LSAA_13918   Lepeophtheirus salmonis IoA-00 CAF3017150.1
CAB4068859.1		    
 LSAA_12467   Lepeophtheirus salmonis IoA-00 CAF2982533.1
CAB4067135.1		    
 LSAA_645 (fragment)   Lepeophtheirus salmonis IoA-00 CAF2780380.1
CAB4055744.1		    
 LSAA_14540   Lepeophtheirus salmonis IoA-00 CAF3036848.1
CAB4069930.1		    
 LSAA_11977 (fragment)   Lepeophtheirus salmonis IoA-00 CAF2982548.1
CAB4067136.1		    
 LSINAPIS_LOCUS6148 (fragment)   Leptidea sinapis VUY94163.1    
 Stv2   Lotus japonicus CAJ15148.2
CAJ15148.1		    
 ORF7   Lupinus angustifolius CCH47222.1    
 SIAT8B (fragment)   Macaca fascicularis AAW55579.1    
 ORF   Macaca fascicularis BAE72949.1    
 ORF (fragment)   Macaca fascicularis BAE72971.1    
 unnamed protein product (fragment)   Macaca fascicularis BAE87253.1    
 unnamed protein product   Macaca fascicularis BAE88437.1    
 CMP-N-acetylneuraminate-β-galactosamide-α-2, 3-sialyltransferase 4 (St3gal4)   Macaca mulatta AFE79710.1
AFH33640.1
AFI38029.1		    
 type 2 lactosamine α-2,3-sialyltransferase (St3gal6)   Macaca mulatta AFE64276.1    
 siα-a-2,3-Gal-β-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (St8sia3)   Macaca mulatta AFE65983.1    
 CMP-N-acetylneuraminate-β-1,4-galactoside α-2,3-sialyltransferase isoform j (St3gal3)   Macaca mulatta AFE79717.1
AFH33647.1		    
 α-N-acetylgalactosaminide α-2,6-sialyltransferase 6 (St6galnac6)   Macaca mulatta AFE65151.1
AFH28687.1		    
 α-N-acetylgalactosaminide α-2,6-sialyltransferase 3 isoform 1 (St6galnac3)   Macaca mulatta AFE77581.1    
 CMP-N-acetylneuraminate-β-galactosamide-α-2, 3-sialyltransferase 2 (St3gal2)   Macaca mulatta AFE75884.1
AFH27656.1
AFI34321.1		    
 CMP-N-acetylneuraminate-β-galactosamide-α-2, 3-sialyltransferase 4 isoform 1 precursor (St3gal4)   Macaca mulatta AFE66355.1
AFI34007.1		    
 lactosylceramide α-2,3-sialyltransferase isoform 1 (St3gal5)   Macaca mulatta AFE66481.1    
 β-galactoside α-2,6-sialyltransferase 2 isoform a, partial (St6gal2) (fragment)   Macaca mulatta AFE70088.1    
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