GlycosylTransferase Family 29

Activities in Familysialyltransferase (EC 2.4.99.-); β-galactoside α-2,6-sialyltransferase (EC 2.4.99.1); α-N-acetylgalactosaminide α-2,6-sialyltransferase (EC 2.4.99.3); β-galactoside α-2,3-sialyltransferase (EC 2.4.99.4); N-acetyllactosaminide α-2,3-sialyltransferase (EC 2.4.99.6); (α-N-acetyl-neuraminyl-2,3-β-galactosyl-1,3)-N-acetylgalactosaminide α-2,6-sialyltransferase (EC 2.4.99.7); α-N-acetyl-neuraminide α-2,8-sialyltransferase (EC 2.4.99.8); lactosylceramide α-2,3-sialyltransferase (EC 2.4.99.9)
Mechanism Inverting
NoteThese enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resourcesCFG(Core1); CFG(Glycosphingolipid); CFG(N-linked); CFG(Terminal); Glymap;
Statistics GenBank accession (1476); Uniprot accession (488); PDB accession (11); 3D entries (4); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 α-2,6-sialyltransferase (fragment) ST6Gal I   Sus scrofa AAD33059.1 Q9XSG8  
 α-2,8-sialyltransferase 8B   Sus scrofa AFV30164.1    
 sialyltransferase (fragment) ST6Gal I   Sus scrofa AAC15633.1 O62717  
 ST6Gal I   Taeniopygia guttata CBQ74105.1 E4ZFH2  
 ST6Gal II   Taeniopygia guttata CBQ74106.1 E4ZFH3  
 α-2,6-sialyltransferase ST6GalNAc IV (siat7D) (fragment)   Takifugu rubripes CAG26698.1
CAB44338.1
CAG29210.1
Q6ZXZ2
Q9W6U6
 
 α-2,3-sialyltransferase ST3Gal III (Siat6)   Takifugu rubripes CAF25176.1
CAG29192.1
Q702S0  
 α-2,3-sialyltransferase ST3Gal I (Siat4)   Takifugu rubripes CAF25174.1
CAG29190.1
Q702S2  
 CMP-NeuAc: β-galactoside α-2,3-sialyltransferase II (ST3Gal II;Siat5) (partial) 2.4.99.4 Takifugu rubripes CAF25175.1
CAG29191.1
Q702S1  
 α-2,6-sialyltransferase ST6GalNAc II (Siat7B)   Takifugu rubripes CAG25681.1
CAG29212.1
Q6ZYN5  
 α-2,6-sialyltransferase ST6GalNAc II B (Siat7B-related)   Takifugu rubripes CAG25682.1
CAG29211.1
Q6ZYN4  
 α-2,6-sialyltransferase ST6GalNAc III (Siat7C) (fragment)   Takifugu rubripes CAG25678.1
CAG29209.1
Q6ZYN9  
 α-2,6-sialyltransferase ST6GalNAc V (Siat7E) (fragment)   Takifugu rubripes CAG26702.1
CAG29208.1
Q6ZXY8  
 α-2,6-sialyltransferase ST6GalNAc VI (Siat7F) (fragment)   Takifugu rubripes CAG26709.1
CAG29207.1
Q6ZXY1  
 α-2,8-sialyltransferase ST8Sia IIIr (Siat 8Cr)   Takifugu rubripes CAG29381.1
CAG29215.1
Q6KC06  
 α-2,8-sialyltransferase ST8Sia VIr (Siat 8Fr)   Takifugu rubripes CAG29389.1
CAG29213.1
Q6KBZ8  
 α-2,8-sialyltransferase ST8Sia I (Siat 8A) (fragment)   Takifugu rubripes CAG29373.1
CAG29218.1
Q6KC14  
 α-2,8-sialyltransferase ST8Sia V (Siat 8E) (fragment)   Takifugu rubripes CAG29386.1
CAG29214.1
Q6KC01  
 α-2,8-sialyltransferase ST8Sia III (Siat 8C) (fragment)   Takifugu rubripes CAG29380.1
CAG29216.1
Q6KC07  
 α-2,8-sialyltransferase ST8Sia II (Siat 8B) (fragment)   Takifugu rubripes CAG29377.1
CAG29217.1
Q6KC10  
 α-2,8-sialyltransferase ST8Sia VI (Siat 8F)   Takifugu rubripes CAG29388.2 Q6KBZ9  
 α-2,3-sialyltransferase (Siat5-r)   Takifugu rubripes CAG32841.1 Q6KB57  
 α-2,6-sialyltransferase ST6Gal I (Siat1)   Takifugu rubripes CAG32836.1
CAG29196.1
Q6KB62  
 α-2,6-sialyltransferase ST6Gal II   Takifugu rubripes CAI29184.1
CAG29197.1
CAG29198.1
Q5QQ37  
 α-2,3-sialyltransferase (Siat4c) (fragment)   Takifugu rubripes CAI26289.1
CAG29193.1
Q5TIL3  
 α-2,3-sialyltransferase (Siat5-r)   Takifugu rubripes CAI26290.2
CAG29194.1
Q5TIL2  
 α-2,3-sialyltransferase ST3Gal V (St3Gal V) (partial)   Takifugu rubripes CAI26253.1
CAG29195.1
Q5TIL7  
 α-2,3-sialyltransferase ST3Gal III (Siat6)   Tetraodon nigroviridis CAF25180.1 Q702R7  
 α-2,6-sialyltransferase ST6GalNAc II (Siat7B)   Tetraodon nigroviridis CAG25683.1 Q6ZYN3  
 α-2,6-sialyltransferase ST6GalNAc V (Siat7E) (fragment)   Tetraodon nigroviridis CAG26708.1 Q6ZXY2  
 α-2,8-sialyltransferase ST8Sia IIIr (Siat 8Cr) (fragment)   Tetraodon nigroviridis CAG29379.1 Q6KC08  
 α-2,8-sialyltransferase ST8Sia III (Siat 8C) (fragment)   Tetraodon nigroviridis CAG29378.1 Q6KC09  
 α-2,8-sialyltransferase ST8Sia II (Siat 8B) (fragment)   Tetraodon nigroviridis CAG29376.1 Q6KC11  
 α-2,8-sialyltransferase ST8Sia I (Siat 8A) (fragment)   Tetraodon nigroviridis CAG29375.1 Q6KC12  
 α-2,8-sialyltransferase ST8Sia V (Siat 8E) (fragment)   Tetraodon nigroviridis CAG29387.1 Q6KC00  
 α-2,3-sialyltransferase ST3Gal I (Siat4)   Tetraodon nigroviridis CAG32838.1 Q6KB60  
 α-2,3-sialyltransferase (Siat5-r)   Tetraodon nigroviridis CAG32842.1 Q6KB56  
 α-2,3-sialyltransferase ST3Gal II (Siat5)   Tetraodon nigroviridis CAI11371.1 Q5TIN7  
 α-2,6-sialyltransferase ST6Gal I (Siat1)   Tetraodon nigroviridis CAI29183.1 Q5QQ38  
 Siat5-r   Tetraodon nigroviridis CAI38425.1 Q5ND95  
 st6Gal II   Tetraodon nigroviridis CAL44592.1 Q0E5A9  
 α-2,8-sialyltransferase ST8Sia VI (siat 8F)   Tetraodon nigroviridis CAL91580.1 A1KQY7  
 Stv2   Triticum aestivum CAJ15156.1 Q4JEY4  
 TRAES_3BF099700040CFD_c1   Triticum aestivum CDM80079.1    
 ST6Gal (fragment)   Varroa destructor ADR32072.1 E5FP61  
 VIGAN_06167100 (Vigan.06g167100)   Vigna angularis var. angularis BAT90425.1    
 VIGAN_01008100 (Vigan.01g008100)   Vigna angularis var. angularis BAT72655.1    
 VIGAN_03219300 (Vigan.03g219300) (fragment)   Vigna angularis var. angularis BAT82217.1    
 VIGAN_04216400 (Vigan.04g216400)   Vigna angularis var. angularis BAT84723.1    
 VITISV_027339   Vitis vinifera CAN64919.1 A5AUF9  
 VITISV_001623   Vitis vinifera CAN64473.1 A5AE78  
 α-2,8-sialyltransferase (ST8Siα-I;Siat8A;GD3 synthase) 2.4.99.8 Xenopus laevis CAG28695.1
AAQ16162.1
AAQ16163.1
ABK58605.1
Q6ZXA0  
 α-2,3-sialyltransferase (St3Gal-II)   Xenopus laevis CAE51386.1 Q70D57  
 α-2,3-sialyltransferase (St3Gal-VI)   Xenopus laevis CAE51390.1
AAH84840.1
Q70D53  
 α-2,3-sialyltransferase St3Gal-III (Siat6)   Xenopus laevis CAE51388.1
AAI69739.1
Q70D55  
 Unknown (protein for MGC:81265)   Xenopus laevis AAH68760.1 Q6NU41  
 Unknown (protein for MGC:114856)   Xenopus laevis AAH97611.1 Q4V814  
 α-2,8-polysialyltransferase (STX) 2.4.99.- Xenopus laevis BAA32617.1
AAI69801.1
O93234  
 Unknown (protein for MGC:181638)   Xenopus laevis AAI53765.1
AAI70140.1
A8E5Y5  
 α-2,3-sialyltransferase ST3Gal I (St3gal1)   Xenopus tropicalis CBE70256.1 D2U4U0  
 α-2,3-sialyltransferase ST3Gal V (St3gal5)   Xenopus tropicalis CBE70258.1 D2U4U2  
 α-2,6-sialyltransferase ST6GalNAc VI (St6galnac6)   Xenopus tropicalis CBE70259.1 D2U4U3  
 α-2,3-sialyltransferase (St3Gal-II)   Xenopus tropicalis CAE51387.1 Q70D56  
 α-2,6-sialyltransferase (Siat7b)   Xenopus tropicalis CAF05849.1
AAI35966.1
Q704X5  
 α-2,3-sialyltransferase (Siat4c)   Xenopus tropicalis CAF22058.1
AAI71325.1
CAJ82163.1
Q703F8  
 α-2,3-sialyltransferase (3Gal-VI) or ST3 β-galactoside α-2,3-sialyltransferase 6   Xenopus tropicalis AAI35191.1
CAF25054.1
CAJ83497.1
A4IGP3  
 β-galactosamide α-2,6-sialyltransferase II (ST6Gal II)   Xenopus tropicalis CAF29496.1 Q701R1  
 α-2,6-sialyltransferase ST6GalNAc V (Siat7E)   Xenopus tropicalis CAG26707.1
AAI35143.1
Q6ZXY3  
 ST6Gal I   Xenopus tropicalis CBQ74109.1 E4ZFH6  
 α-2,8-sialyltransferase ST8Sia III (Siat 8C) (fragment)   Xenopus tropicalis CAG29383.1 Q6KC04  
 sialytransferase (St8SiaI)   Xenopus tropicalis AAT67042.2
AAI70804.1
Q6DNG6  
 TGas108m23.1-001   Xenopus tropicalis CAJ81569.1 Q28F54  
 Unknown (protein for MGC:146298)   Xenopus tropicalis AAI21421.1 Q0V9R7  
 Unknown (protein for MGC:145910)   Xenopus tropicalis AAI21365.1 Q0V9X0  
 st3gal3   Xenopus tropicalis AAI21864.1
AAI35194.1
CAF25181.1
Q0P4X4  
 α-2,8-sialyltransferase ST8Sia VI (siat 8F)   Xenopus tropicalis CAL91578.1 A1KQY5  
 α-2,8-sialyltransferase ST8Sia V (siat 8E)   Xenopus tropicalis CAM12265.1 A2BCP7  
 α-2,8-sialyltransferase ST8Sia VI (siat 8F)   Xenopus tropicalis CAM12266.1 A2BCP8  
 Unknown (protein for MGC:172697)   Xenopus tropicalis AAI54087.1 A8KBE9  
 unknown   Zea mays ACG40703.1 B6TUC0  
 unknown   Zea mays ACG44732.1 B6U5U9  
 stv2   Zea mays CAJ44459.1
ACG37363.1
ACN26679.1
Q2WBH7  
 stv3   Zea mays CAJ44460.1
ACG46171.1
Q2WBH6  
 unknown   Zea mays B73 ACN30607.1 C0P8W2  
 unknown (ZM_BFb0033E17) (fragment)   Zea mays B73 ACF80036.1 B4FD43  
 unknown (ZM_BFb0205E19)   Zea mays B73 ACF82979.1
ACF84848.1
ACR34246.1
ACR37671.1
ACR37696.1
B4FLI6  
 unknown (ZM_BFc0043H17)   Zea mays B73 ACF84769.1 B4FRM6  
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