GlycosylTransferase Family 29

Activities in Familysialyltransferase (EC 2.4.99.-); β-galactoside α-2,6-sialyltransferase (EC 2.4.99.1); α-N-acetylgalactosaminide α-2,6-sialyltransferase (EC 2.4.99.3); β-galactoside α-2,3-sialyltransferase (EC 2.4.99.4); N-acetyllactosaminide α-2,3-sialyltransferase (EC 2.4.99.6); (α-N-acetyl-neuraminyl-2,3-β-galactosyl-1,3)-N-acetylgalactosaminide α-2,6-sialyltransferase (EC 2.4.99.7); α-N-acetyl-neuraminide α-2,8-sialyltransferase (EC 2.4.99.8); lactosylceramide α-2,3-sialyltransferase (EC 2.4.99.9)
Mechanism Inverting
NoteThese enzymes use CMP-beta-N-acetylneuraminate as the sugar donor
External resourcesCFG(Core1); CFG(Glycosphingolipid); CFG(N-linked); CFG(Terminal); Glymap;
Statistics GenBank accession (1505); Uniprot accession (488); PDB accession (13); 3D entries (5); cryst (0)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Siat7d   Oryzias latipes CAI39647.1 Q5K024  
 Siat8e   Oryzias latipes CAI39652.1 Q5K019  
 Siat7   Oryzias latipes CAI39645.1 Q5K026  
 Siat8a   Oryzias latipes CAI39649.1 Q5K022  
 Siat1   Oryzias latipes CAI39643.1 Q5K028  
 Siat7c   Oryzias latipes CAI39646.1 Q5K025  
 α-2,8-sialyltransferase ST8Sia II (siat 8B) (partial)   Oryzias latipes CAM12263.1 A2BCP5  
 α-2,8-sialyltransferase ST8Sia VI (siat 8F)   Oryzias latipes CAM12267.1 A2BCP9  
 ST6Gal I/II (short fragment)   Oscarella carmela CBQ74118.1 E4ZFI5  
 β-galactosamide α-2,6-sialyltranferase 1 (St6Gal1)   Ovis aries AFF27582.1    
 lactosylceramide α-2,3-sialyltransferase   Ovis aries AGR44671.1    
 α-2,3-sialyltransferase (st3gal4)   Ovis aries CAP09696.1 A8E1W0  
 α-2,3-sialyltransferase ST3Gal IV (Siat4c)   Pan troglodytes CAF25182.1 P61130  
 β-galactosamide α-2,6-sialyltransferase II (ST6Gal II)   Pan troglodytes CAF29493.1 Q701R4  
 β-galactosamide α-2,6-sialyltransferase I (ST6Gal I; Siat1) 2.4.99.1 Pan troglodytes CAF29492.1 Q701R5  
 α-2,6-sialyltransferase ST6GalNAc III (Siat7C)   Pan troglodytes CAG25676.1 Q6ZYP1  
 α-2,8-sialyltransferase 8A (Siat8A) 2.4.99.8 Pan troglodytes CAG26896.1 P61642  
 Siat8E   Pan troglodytes CAG26900.1 P61646  
 α-2,6-sialyltransferase ST6GalNAc IV (Siat7D) (fragment)   Pan troglodytes CAG26699.1 Q6ZXZ1  
 α-2,8-sialyltransferase 8C (Siat8C)   Pan troglodytes CAG26898.1 P61644  
 α-2,6-sialyltransferase ST6GalNAc VI (Siat7F) (fragment)   Pan troglodytes CAG26711.1 Q6ZXX9  
 α-2,8-sialyltransferase 8B (Siat8B)   Pan troglodytes CAG26897.1 P61643  
 Siat8F   Pan troglodytes CAG26901.1 P61648  
 α-2,6-sialyltransferase ST6GalNAc V (Siat7E)   Pan troglodytes CAG26704.1 Q6ZXY6  
 α-2,8-sialyltransferase 8D (Siat8D)   Pan troglodytes CAG26899.1 P61645  
 α-2,3-sialyltransferase ST3Gal VI (Siat10)   Pan troglodytes CAG32844.1 Q6KB54  
 α-2,3-sialyltransferase ST3Gal II (Siat5)   Pan troglodytes CAG32840.1 Q6KB58  
 α-2,3-sialyltransferase ST3Gal I (Siat4)   Pan troglodytes CAG32839.1 Q6KB59  
 GM3 synthase ST3Gal V (Siat9)   Pan troglodytes CAG32843.1 Q6KB55  
 α-2,6-sialyltransferase (Sia7A)   Pan troglodytes CAG38615.1 Q6H8N5  
 α-2,6-sialyltransferase (Sia7B)   Pan troglodytes CAG38616.1 Q6H8N4  
 ST6Gal I/II (fragment)   Petromyzon marinus CBQ74113.1 E4ZFI0  
 ST6Gal I/II (partial)   Petromyzon marinus CBQ74114.1 E4ZFI1  
 ST6Gal I/II (fragment)   Petromyzon marinus CBQ74115.1 E4ZFI2  
 Siat8D (partial)   Petromyzon marinus CAP12782.1 B0BEX3  
 Siat8A (partial)   Petromyzon marinus CAP12783.1 B0BEX4  
 Siat8F (partial)   Petromyzon marinus CAP12784.1 B0BEX5  
 stv1   Physcomitrella patens CAJ44463.1 Q2WBH3  
 Stv1   Picea glauca CAJ15153.1 Q4JEY7  
 WS02746_B13   Picea sitchensis ABR16532.1 B8LLK2  
 WS02766_P05   Picea sitchensis ABR17214.1 B8LNI4  
 DKFZp468L1910   Pongo abelii CAH89922.1 Q5RE85  
 DKFZp469M0718   Pongo abelii CAH90474.1 Q5RCN3  
 DKFZp469B1325   Pongo abelii CAH92215.1
CAH89699.1
Q5R7P5  
 DKFZp459I0536   Pongo abelii CAH90316.1 Q5RD41  
 DKFZp459I191   Pongo abelii CAI29584.1 Q5NVS9  
 α-2,3-sialyltransferase ST3Gal VI   Rattus norvegicus CAF25053.1
AAH92560.1
P61943  
 α-2,3-sialyltransferase ST3Gal IV (Siat4c)   Rattus norvegicus CAF25183.1
AAH89057.1
P61131  
 β-galactosamide α-2,6-sialyltransferase II (ST6Gal II)   Rattus norvegicus CAF29494.1 Q701R3  
 α-2,6-sialyltransferase ST6GalNAc I (Siat7A)   Rattus norvegicus CAG25684.1 Q6ZYN7  
 α-2,6-sialyltransferase ST6GalNAc II (Siat7B)   Rattus norvegicus CAG25679.1
AAH99812.1
Q6ZYN8  
 α-2,6-sialyltransferase ST6GalNAc V (Siat7E)   Rattus norvegicus CAG26701.1 Q6ZXY9  
 α-2,6-sialyltransferase ST6GalNAc VI (Siat7F) (fragment)   Rattus norvegicus CAG26710.1
AAH91354.1
Q6ZXY0  
 α-2,6-sialyltransferase ST6GalNAc IV (Siat7D) (fragment)   Rattus norvegicus CAG26700.1 Q6ZXZ0  
 α-2,8-sialyltransferase (SIAT8E)   Rattus norvegicus CAG27884.1 Q6ZXC8  
 sialyltransferase I (ST3Gal-I;St3galI;Siat4A) (St3gal1)   Rattus norvegicus CAG44449.1 Q6H8N0  
 α-2,3-sialyltransferase III (ST3GalIII;ST3N;Siat6) (St3gal3) 2.4.99.6 Rattus norvegicus AAA42146.1
CAS91694.1
NP_113885.1
Q02734  
 α-2,6-sialyltransferase ST6GalNAc III 2.4.99.- Rattus norvegicus AAC42086.1
AAH72501.1
NP_061996.1
Q64686  
 α-2,8-sialyltransferase 1 / GD3 synthase (ST8SiaI;Siat8a;Siat8) (St8sia1) 2.4.99.8 Rattus norvegicus AAC27541.1
BAA08213.1
P70554  
 α-2,8-sialyltransferase ST8Sia III 2.4.99.- Rattus norvegicus AAB50061.1
NP_037161.1
P97877  
 α-2,8-sialyltransferase ST8Sia II 2.4.99.- Rattus norvegicus AAA42147.1
NP_476497.1
Q07977  
 β-galactoside α-2,6-sialyltransferase I (ST6GalI;ST6Gal1;Siat1) 2.4.99.1 Rattus norvegicus AAA41196.1
AAB07233.1
NP_671738.1
P13721 4MPS[A,B]
 α-2,6-sialyltransferase II (ST3GalII;Siat5;Siat4c) (St3gal2) 2.4.99.4 Rattus norvegicus CAA54293.1
NP_113883.1
Q11205  
 GM3 synthase ST3Gal V   Rattus norvegicus BAA33492.1
AAH78798.1
NP_112627.1
O88830
Q68G12
 
 α-2,8-sialyltransferase (Siat8D;ST8Sia IV) 2.4.99.- Rattus norvegicus AAB49989.1
CAL91579.1
O08563  
 α-2,8-sialyltransferase (SIAT8F)   Rattus norvegicus Sprague-Dawley CAG27885.1 Q6ZXC7  
 Stv2   Saccharum officinarum CAJ15154.1 Q4JEY6  
 ORF   Saccoglossus kowalevskii ALR88578.1    
 ORF   Saccoglossus kowalevskii ALR88573.1    
 ORF   Saccoglossus kowalevskii ALR88575.1    
 ORF   Saccoglossus kowalevskii ALR88574.1    
 ORF   Saccoglossus kowalevskii ALR88577.1    
 ORF   Saccoglossus kowalevskii ALR88576.1    
 ORF   Saccoglossus kowalevskii ALR88589.1    
 ORF   Saccoglossus kowalevskii ALR88579.1    
 α-N-acetylgalactosaminide α-2,6-sialyltransferase 3 (Sia7C)   Salmo salar ACI33495.1 B5X2G4  
 α-N-acetylgalactosaminide α-2,6-sialyltransferase 6 (Sia7F)   Salmo salar ACI33752.1 B5X371  
 SMAX5B_006324   Scophthalmus maximus AWP04321.1    
 SMAX5B_015312   Scophthalmus maximus AWO99580.1    
 SMAX5B_006324   Scophthalmus maximus AWP04318.1    
 SMAX5B_005838   Scophthalmus maximus AWP03707.1    
 SMAX5B_000667   Scophthalmus maximus AWO99396.1    
 SMAX5B_006324   Scophthalmus maximus AWP04317.1    
 SMAX5B_006324   Scophthalmus maximus AWP04319.1    
 SMAX5B_007793   Scophthalmus maximus AWO98084.1    
 SMAX5B_006324   Scophthalmus maximus AWP04320.1    
 SMAX5B_005778   Scophthalmus maximus AWP03706.1    
 SMAX5B_010435   Scophthalmus maximus AWP07471.1    
 SMAX5B_002805   Scophthalmus maximus AWP02332.1    
 SMAX5B_022634 (fragment)   Scophthalmus maximus AWP11001.1    
 SMAX5B_017992   Scophthalmus maximus AWP14011.1    
 SMAX5B_013966 (fragment)   Scophthalmus maximus AWP15464.1    
 SMAX5B_019103   Scophthalmus maximus AWP12516.1    
 SMAX5B_013838   Scophthalmus maximus AWP15501.1    
 SMAX5B_003966   Scophthalmus maximus AWP08891.1    
 SMAX5B_002963   Scophthalmus maximus AWP14892.1    
 SMAX5B_019103   Scophthalmus maximus AWP12515.1    
 SMAX5B_018246   Scophthalmus maximus AWP13316.1    
 SMAX5B_009940 (fragment)   Scophthalmus maximus AWP08490.1    
 SMAX5B_013773   Scophthalmus maximus AWP15500.1    
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