GlycosylTransferase Family 27

Known Activities	polypeptide α-N-acetylgalactosaminyltransferase (EC 2.4.1.41)
Mechanism	Retaining
3D Structure Status	GT-A
Note	Distant similarity to families GT2, GT12 and GT21
External resources	CFG(Mucin); CFG(O-linked);
Statistics	GenBank accession (763); Uniprot accession (211); PDB accession (5); 3D entries (3); cryst (0)

Summary

All (216) Bacteria (13) Eukaryota (201) unclassified (2) Structure (3 ) Characterized (51)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 1 (GalNT1;GalNAc-T1)	2.4.1.41	Bos taurus	AAA30532.1 AAA68489.1 AAE24810.1 AAE24816.1 NP_803485.1	Q07537
ZK688.8 (gly3)	2.4.1.41	Caenorhabditis elegans Bristol N2	AAA28224.3 AAC13669.1 CCD62541.1 NP_498722.1	P34678.2
Y116F11B.12 (Gly-4)	2.4.1.41	Caenorhabditis elegans Bristol N2	AAC13670.1 CAB81983.1 CAB81985.3 CAC14394.1 CBA11615.1 NP_507850.1	Q8I136 Q8I136.2
H38K22.5 (Gly-6)	2.4.1.41	Caenorhabditis elegans Bristol N2	AAC13674.1 AAC13675.1 AAC13676.1 CAA19707.1 CAC42317.1 CAC42318.1 CAX65062.2 NP_001022644.1	O61394.1
Y46H3A.6 (gly-7)	2.4.1.41	Caenorhabditis elegans Bristol N2	AAC13677.1 AAF60620.1 CCD70652.1 NP_503512.1	O61397.1
Y66A7A.6 (gly-8)	2.4.1.41	Caenorhabditis elegans Bristol N2	AAC13678.1 CAA21500.1 CAC35860.1 NP_499504.1	O45293.1
GLY9 (Y47D3A.23)	2.4.1.41	Caenorhabditis elegans Bristol N2	AAC13679.1 CAB57897.1 CAI46621.1 NP_499451.1	Q9U2C4 Q9U2C4.1
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T3	2.4.1.41	Cryptosporidium parvum	AAQ95175.1	Q6TBQ9
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T1	2.4.1.41	Cryptosporidium parvum	AAQ95174.1	Q6TBR0
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T4 (fragment)	2.4.1.41	Cryptosporidium parvum	AAQ95176.1	Q6TBQ8
polypeptide N-acetylgalactosaminyltransferase T4 (CG31956;AT25481p1)	2.4.1.41	Drosophila melanogaster	AAN10370.1 AAN75751.1 AAQ56701.1 ACL82986.1 AER27632.1 NP_722910.1	B7Z006 Q8IA42 Q8IA42.2
polypeptide N-acetylgalactosaminyltransferase T3 (CG4445)	2.4.1.41	Drosophila melanogaster	AAD38630.1 AAF59298.1 NP_610256.1	Q9Y117
polypeptide N-acetylgalactosaminyltransferase T35A / l(2)35Aa (Pgant35A;CG7480)	2.4.1.41	Drosophila melanogaster	AAF44871.1 AAF53391.1 AAK66862.1 AAM62405.1 AAM62406.1 AAM62407.1 AEG66944.1 NP_652069.2	Q8MVS5 Q8MVS5.2
polypeptide N-acetylgalactosaminyltransferase T7 (CG6394)	2.4.1.41	Drosophila melanogaster	AAF48851.1 AAM62412.1 AAN09470.1 AAQ56704.1 AAV37008.1 NP_573301.2 NP_728178.1	Q8MV48 Q8MV48.2
polypeptide N-acetylgalactosaminyltransferase T6 (CG2103)	2.4.1.41	Drosophila melanogaster	AAF47689.1 AAF47690.1 AAL29177.1 AAQ56703.1 NP_647749.2 NP_728779.1	Q6WV16
polypeptide N-acetylgalactosaminyltransferase T8 (CG7297)	2.4.1.41	Drosophila melanogaster	AAF49587.1 AAL48588.1 NP_648800.1	Q9VUT6
polypeptide N-acetylgalactosaminyltransferase T2 (CG3254)	2.4.1.41	Drosophila melanogaster	AAF51113.2 AAF51113.3 AAQ22499.1 AAQ56700.1 AAS64620.1 AAS64620.2 NP_608773.1	Q6WV19
polypeptide N-acetylgalactosaminyltransferase T5 (CG31651)	2.4.1.41	Drosophila melanogaster	AAF52218.2 AAL25377.1 AAQ56702.1 ABI31292.1 NP_608906.2	Q6WV17
polypeptide N-acetylgalactosaminyltransferase T1 (CG8182)	2.4.1.41	Drosophila melanogaster	AAF58130.1 AAG13184.1 AAM29416.1 AAM70974.1 AAQ56699.1 NP_611043.1 NP_725472.1	Q6WV20
N-acetylgalactosaminyltransferase (ppGalNAc-T1)	2.4.1.41	Echinococcus granulosus	AAQ56593.1	Q6V2D0
UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 2 (GALNTL2;GALNT7)	2.4.1.41	Homo sapiens	AAE72285.1 AAE73125.1 AAH14789.1 AAH30625.1 AAK63127.1 AAQ88808.1 ABA31473.1 ABA36473.1 ABA38055.1 ABA68732.1 ABA69735.1 ABA70117.1 ABA70240.1 ABC04061.1 ABC16096.1 ABE23551.1 ABE26114.1 ABE26387.1 ABH64624.1 ABH64747.1 ABH64904.1 ABH66133.1 ABH70952.1 ABH71075.1 ABH72589.1 ABH75704.1 ABH99489.1 ABI02594.1 ABI07395.1 ABI11043.1 ABI12263.1 ABJ19428.1 ABJ34423.1 ABL21883.1 ABX94001.1 ABX96294.1 ABX96604.1 ABY05068.1 ABY16007.1 ABY18804.1 ACC22268.1 ACC22839.1 ACC23718.1 ACC32509.1 ACC34084.1 ACE08795.1 ACG89706.1 ACK00002.1 ACM95112.1 ACN08875.1 ACP73867.1 ACS06493.1 ACS08649.1 ACW23860.1 BAD29961.1 BAG52928.1 CAD38585.1 CAD44542.1 CAD89983.1 CAG32963.1 CAK32357.1 NP_473451.2	Q8N3T1.2
Polypeptide GalNAc transferase T13 (contains KIAA1918)	2.4.1.41	Homo sapiens	AAF19246.1 AAI01032.1 AAI01034.1 AAI01035.1 ACC22253.1 BAC54545.1 BAG54747.1 CAD44533.2 CAG32964.1 NP_443149.2	Q68VI8 Q8IUC8
UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 14 (GalNT14)	2.4.1.41	Homo sapiens	AAH06269.1 AAH06269.2 AAH10659.1 AAQ89118.1 AAX88899.1 ABA66763.1 ABH82928.1 ABI02314.1 ABI12599.1 ABJ30825.1 ABJ38955.1 ABX91594.1 ABX91870.1 ABX92146.1 ABX92422.1 ABX92698.1 ABX93132.1 ABX93639.1 ABX94373.1 ABX95380.1 ABX95656.1 ABX95932.1 ABY04154.1 ABY04430.1 ABY04706.1 ABY05292.1 ABY16398.1 ABY17890.1 ABY18166.1 ABY18442.1 ACC25543.1 ACC26284.1 ACC36580.1 ACC36856.1 ACE07501.1 ACE09339.1 ACE10551.1 ACJ96114.1 ACN02380.1 ACN06790.1 ACP73505.1 ACP89033.1 ACR88983.1 ACR89535.1 ACW28625.1 BAB14227.1 BAB14795.1 BAC03634.1 BAC56889.1 BAG53701.1 BAH12861.1 CAA70505.3 CAA70505.4 CAD10224.1 CAD34770.1 CAD44543.1 CAE91230.1 CAE91506.1 NP_078848.2	Q96FL9
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase GalNT11 (FLJ21634)	2.4.1.41	Homo sapiens	AAD45821.1 AAH59377.1 ABA85638.1 ACC22266.1 BAB15105.1 BAB15338.1 BAG54116.1 BAH12901.1 CAC79625.2 CAC79625.3 CAD38481.1 NP_071370.2	Q8NCW6 Q8NCW6.2
UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferase T4 (GalNAc-T4;GALNT4)	2.4.1.41	Homo sapiens	AAH36390.1 AAN94203.1 AAN94205.1 BAG35722.1 BAG60038.1 CAA69875.1 NP_003765.1	Q8N4A0 Q8N4A0.1
UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferase T1 (GalNAc-T1;GALNT1)	2.4.1.41	Homo sapiens	AAC50327.1 AAH38440.1 AAH47746.1 ACC22256.1 BAF85751.1 CAA59380.1 CAD44535.1 NP_065207.2	Q10472 Q10472.1
UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferase T2 (GalNAc-T2;GalNT2)	2.4.1.41	Homo sapiens	AAH41120.1 ACS13744.1 BAF82737.1 BAH12448.1 BAH13288.1 BAH14094.1 CAA59381.1 CAC00585.2 CAI22902.1 CAI23447.1 NP_004472.1	Q10471	2FFU[A] 2FFV[A,B]
UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferase T3 (GALNAc-T3;GALNT3)	2.4.1.41	Homo sapiens	AAH56246.1 AAI13566.1 AAI13568.1 AAY14678.1 BAG36187.1 CAA63371.1 CAD44536.1 NP_004473.1	Q14435
UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferase T6 (GalNAc-T6)	2.4.1.41	Homo sapiens	AAH35822.2 AAI14506.1 BAB15297.1 BAC11118.1 BAG52560.1 BAG59418.1 BAJ10977.1 CAA69876.1 CAF85889.1 CAM83953.1 CAM83954.1 NP_009141.1 NP_009141.2	D7UNW5 Q8NCL4 Q8NCL4.2
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5 (GALNT5)	2.4.1.41	Homo sapiens	AAF15313.1 AAI42677.1 AAP34404.1 ACC22260.1 BAF84843.1 CAB65104.1 CAD44537.1 NP_055383.1 XP_050509.1	A5PKZ1 Q7Z7M9 Q7Z7M9.1
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7 (Galnt7)	2.4.1.41	Homo sapiens	AAH35303.1 AAH46129.1 AAH47468.1 AAY41020.1 BAG52155.1 BAG58426.1 CAB60270.1 CAC39783.1 CAD44538.1 CAI72154.1 NP_059119.1	B3KQU3 Q86SF2 Q86SF2.1
polypeptide GalNAc transferase 8 (GalNAc-T8)	2.4.1.41	Homo sapiens	CAD44539.1 NP_059113.1	Q9NY28
polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)	2.4.1.41	Homo sapiens	AAH69354.1 AAH93817.1 AAH93817.2 AAH93819.1 AAH93819.2 AAI57846.1 AAI71844.1 AAM49722.1 AAT18857.1 ABE14200.1 BAB13699.2 BAG51429.1 BAG51570.1 CAD44540.1 NP_068580.1	Q9HCQ5 Q9HCQ5.3
UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 10 (GalNT10;pp-GalNAc-T10)	2.4.1.41	Homo sapiens	AAH07224.2 AAH50333.1 AAH72450.1 AAH98444.1 AAP65370.1 AAP65371.1 AAP65372.1 AAP65373.1 AAP65374.1 AAP65376.1 AAP65377.1 AAP65378.1 AAP65379.1 ABA33146.1 ABA33147.1 ABA33148.1 ABA33149.1 ABA33150.1 ABA33151.1 ABA33152.1 ABA33153.1 ABA33154.1 ABA33155.1 BAB14676.1 BAB84958.1 BAC56890.1 BAG54441.1 CAB46378.1 CAD44532.1 CAE91109.1 NP_060010.2 NP_938080.1	Q86SR1 Q86SR1.2	2D7I[A] 2D7R[A]
UDP-GalNAc: polypeptide α-N-acetylgalactosaminyltransferase T1 (GalNAc-T1;ppGalNAcTase-1;Galnt1)	2.4.1.41	Mus musculus	AAB58477.1 AAH56215.1 AAH90962.1 BAE28617.1 NP_038842.2	O08912 O08912.1	1XHB[A]
Polypeptide GalNAc transferase T3 (GALNT3)	2.4.1.41	Mus musculus	AAB09579.1 AAH43331.1 ABE17770.1 BAE22551.1 CAM20333.1 CAM21878.1 NP_056551.1	P70419 P70419.2
Polypeptide GalNAc transferase T4	2.4.1.41	Mus musculus	AAB58301.1 AAH57882.1 ABA38430.1 BAC28317.1 BAE28303.1 BAE31844.1 NP_056552.1	O08832.1
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7 (Galnt7)	2.4.1.41	Mus musculus	AAH07484.1 AAH49907.1 AAH52461.1 AAK37549.1 BAC28284.1 BAC29461.1 BAC31068.1 BAE30388.1 BAE30662.1 BAE31034.1 BAE31754.1 NP_653332.2	Q80VA0 Q80VA0.2
polypeptide N-acetylgalactosaminyltransferase T2 (Galnt2)	2.4.1.41	Mus musculus	AAH07172.1 AAH53063.1 AAH59818.1 AAK37548.1 BAC32790.1 BAE26246.1 BAE30483.1 NP_644678.1	Q6PB93
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase GalNT11	2.4.1.41	Mus musculus	AAH11428.1 AAH21504.1 AAH34184.1 AAH34185.1 AAH36143.1 AAH36145.1 AAQ06668.1 BAC40096.1 BAE36442.1 CAC79626.1	Q921L8 Q921L8.1
Polypeptide GalNAc transferase T6	2.4.1.41	Mus musculus C57BL/6J	AAI19325.1 AAI19327.1 BAC25984.1 BAC33618.1 BAE32989.1 BAE35316.1 CAB55352.1 NP_766039.1	Q0VE84 Q8C7U7 Q8C7U7.1
Polypeptide GalNAc transferase T6	2.4.1.41	Rattus norvegicus	AAC99426.1 NP_075215.1	Q9R0C5
UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase T1 (GalNAc-T1)	2.4.1.41	Rattus norvegicus	AAC52511.1 NP_077349.1	Q10473
N-acetylgalactosaminyltransferase T5 (Galnt5)	2.4.1.41	Rattus norvegicus	AAC69708.1 NP_113984.1	O88422.1
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T9	2.4.1.41	Rattus norvegicus	AAK54498.1 EDM04502.1 NP_570098.1	Q925R7
polypeptide N-acetylgalactosaminyltransferase T1	2.4.1.41	Sus scrofa	BAA12800.1	Q29121
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T1 (ppGalNAc-T1)	2.4.1.41	Toxoplasma gondii	AAM81085.1 AAM81087.1	Q8MM26
UDP-GalNac:polypeptide N-acetylgalactosaminyltransferase T2 (ppGalNAc-T2)	2.4.1.41	Toxoplasma gondii	AAM95450.1 AAQ95172.1	Q6YK77
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T5 (ppGalNAc-T5) (fragment)	2.4.1.41	Toxoplasma gondii	AAQ95171.1	Q6TBR3
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T4 (ppGalNAc-T4) (fragment)	2.4.1.41	Toxoplasma gondii	AAQ95170.1	Q6TBR4
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T3 (ppGalNAc-T3)	2.4.1.41	Toxoplasma gondii	AAO20278.1 AAQ95173.1	Q6YBY0

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.