GlycosylTransferase Family 22

Activities in FamilyDol-P-Man: Man6GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.259); Dol-P-Man: Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.261); Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-); Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-)
Mechanism Inverting
3D Structure StatusGT-C
NoteThese enzymes use dolichol-P-mannose as the sugar donor.
External resourcesGlymap; GPI:PIG-B; GPI:SMP3;
Statistics GenBank accession (1081); Uniprot accession (169);
All (916) Bacteria (50) Eukaryota (866) Characterized (9)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 KLMA_10289   Kluyveromyces marxianus DMKU3-1042 BAO37911.1    
 KLMA_50609   Kluyveromyces marxianus DMKU3-1042 BAO41263.1    
 KLMA_60009   Kluyveromyces marxianus DMKU3-1042 BAO41300.1    
 KLMA_70199   Kluyveromyces marxianus DMKU3-1042 BAO42047.1    
 KMAR_70180   Kluyveromyces marxianus NBRC 1777 BAP73464.1    
 KMAR_10260   Kluyveromyces marxianus NBRC 1777 BAP69468.1    
 KMAR_50577   Kluyveromyces marxianus NBRC 1777 BAP72710.1    
 KMAR_60013   Kluyveromyces marxianus NBRC 1777 BAP72752.1    
 ATY40_BA7504787   Komagataella pastoris ATCC 28485 ANZ77971.1    
 ATY40_BA7501896 (Alg9)   Komagataella pastoris ATCC 28485 ANZ76086.1    
 ATY40_BA7503628   Komagataella pastoris ATCC 28485 ANZ76438.1    
 ATY40_BA7501899 (Gpi10)   Komagataella pastoris ATCC 28485 ANZ75139.1    
 AT249_GQ6704004   Komagataella phaffii ATCC 76273 AOA63595.1    
 AT249_GQ6701318 (Gpi10)   Komagataella phaffii ATCC 76273 AOA62252.1    
 AT249_GQ6701321 (Alg9)   Komagataella phaffii ATCC 76273 AOA62820.1    
 AT249_GQ6704914   Komagataella phaffii ATCC 76273 AOA65114.1    
 PP7435_CHR2-0033 (Alg9)   Komagataella phaffii CBS 7435 CCA37732.2    
 PP7435_CHR3-0292 (Smp3)   Komagataella phaffii CBS 7435 CCA39262.2    
 PP7435_Chr2-0036   Komagataella phaffii CBS 7435 CCA37735.1    
 PP7435_Chr4-0430   Komagataella phaffii CBS 7435 CCA40597.1    
 PAS_chr2-2_0039   Komagataella phaffii GS115 CAY69897.1
AOA67355.1
C4R323  
 PAS_chr2-2_0036   Komagataella phaffii GS115 CAY69900.1
AOA67775.1
C4R326  
 PAS_chr3_0882   Komagataella phaffii GS115 CAY70939.1
AOA69284.1
C4R5V3  
 PAS_chr4_0544   Komagataella phaffii GS115 CAY71804.1
AOA69818.1
C4R879  
 KLTH0F09570g   Lachancea thermotolerans CBS 6340 CAR24183.1    
 KLTH0G02684g   Lachancea thermotolerans CBS 6340 CAR24718.1    
 KLTH0A06710g   Lachancea thermotolerans CBS 6340 CAR21307.1    
 KLTH0B08096g   Lachancea thermotolerans CBS 6340 CAR21702.1    
 LbrM35_V2.1330   Leishmania braziliensis MHOM/BR/75/M2904 CAM43885.1 A4HNY0  
 LDBPK_120145   Leishmania donovani BPK282A1 CBZ32416.1    
 LDBPK_361260   Leishmania donovani BPK282A1 CBZ38564.1    
 LinJ12.0140   Leishmania infantum JPCM5 CAM66323.1
CBZ08405.1
   
 LinJ36.1430   Leishmania infantum JPCM5 CAM72592.1    
 LmjF12.0160   Leishmania major strain Friedlin CAJ02436.1
CAC02000.2
   
 LmjF36.1200   Leishmania major strain Friedlin CAJ09073.1 Q4Q1V6  
 LMXM_12_0160   Leishmania mexicana MHOM/GT/2001/U1103 CBZ24607.1    
 LMXM_36_1200   Leishmania mexicana MHOM/GT/2001/U1103 CBZ25963.1    
 LPMP_351230 (Gpi10)   Leishmania panamensis MHOM/PA/94/PSC-1 AIO02260.1    
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX92137.1 E5R5G7  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY01102.1 E5ABR1  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX94234.1 E4ZS54  
 ORF (fragment)   Leptosphaeria maculans JN3 v23.1.3 CBX95449.1 E4ZV23  
 LRAMOSA06507 (fragment)   Lichtheimia ramosa CDS14337.1    
 LRAMOSA01685 (fragment)   Lichtheimia ramosa CDS07736.1    
 LRAMOSA01686 (fragment)   Lichtheimia ramosa CDS07737.1    
 LRAMOSA10440   Lichtheimia ramosa CDS09080.1    
 LRAMOSA03183 (fragment)   Lichtheimia ramosa CDS10508.1    
 LRAMOSA03184 (fragment)   Lichtheimia ramosa CDS10509.1    
 ORF (fragment)   Macaca fascicularis BAB21931.1 Q9BGV0  
 dol-P-Man:Man(7)GlcNAc(2)-PP-Dol α-1,6-mannosyltransferase (Alg12)   Macaca mulatta AFE67025.1    
 α-1,2-mannosyltransferase ALG9 isoform b, partial (Alg9) (fragment)   Macaca mulatta AFE71133.1    
 PigZ (fragment)   Macaca mulatta AFE68824.1    
 dol-P-Man:Man(7)GlcNAc(2)-PP-Dol α-1,6-mannosyltransferase (Alg12)   Macaca mulatta AFH28280.1    
 α-1,2-mannosyltransferase ALG9 isoform b (Alg9)   Macaca mulatta AFH28505.1    
 MGG_04979   Magnaporthe oryzae 70-15 XP_003712478.1
XP_359798.1
   
 MGG_09909   Magnaporthe oryzae 70-15 XP_003710006.1
XP_365064.1
   
 MGG_14835   Magnaporthe oryzae 70-15 XP_003717392.1
XP_365897.1
   
 MGG_06391   Magnaporthe oryzae 70-15 XP_003717180.1
XP_369876.1
   
 MSYG_2720 (fragment)   Malassezia sympodialis ATCC 42132 SHO78377.1    
 MSYG_2891 (fragment)   Malassezia sympodialis ATCC 42132 SHO78544.1    
 MSYG_1111 (fragment)   Malassezia sympodialis ATCC 42132 SHO76772.1    
 MtrDRAFT_AC125474g11v1   Medicago truncatula ABE96653.1 G7IH72  
 MtrDRAFT_AC121246g23v2   Medicago truncatula ABE92826.1    
 BN887_00118   Melanopsichium pennsylvanicum 4 CDI51288.1    
 BN887_00798   Melanopsichium pennsylvanicum 4 CDI56652.1    
 BN887_06093 (fragment)   Melanopsichium pennsylvanicum 4 CDI53051.1    
 MICPUN_63738   Micromonas commoda sp. RCC299 ACO66829.1 C1EFC5  
 MICPUN_79984 (fragment)   Micromonas commoda sp. RCC299 ACO62219.1 C1E1S6  
 MICPUN_57621   Micromonas commoda sp. RCC299 ACO62525.1 C1E3B3  
 MICPUN_81043   Micromonas commoda sp. RCC299 ACO63158.1 C1E4Q1  
 GNLVRS01_PISO0A02508g (Piso0_000123)   Millerozyma farinosa CBS 7064 CCE72541.1    
 GNLVRS01_PISO0B02619g (Piso0_000123)   Millerozyma farinosa CBS 7064 CCE73104.1    
 GNLVRS01_PISO0H11865g (Piso0_003417)   Millerozyma farinosa CBS 7064 CCE81069.1    
 GNLVRS01_PISO0G11864g (Piso0_003417)   Millerozyma farinosa CBS 7064 CCE80304.1    
 GNLVRS01_PISO0D10343g (Piso0_001072)   Millerozyma farinosa CBS 7064 CCE79035.1    
 GNLVRS01_PISO0C10276g (Piso0_001072)   Millerozyma farinosa CBS 7064 CCE78449.1    
 GNLVRS01_PISO0L22627g (Piso0_004699)   Millerozyma farinosa CBS 7064 CCE85127.1    
 GNLVRS01_PISO0K22626g (Piso0_004699)   Millerozyma farinosa CBS 7064 CCE84096.1    
 ORF   Mus musculus AAH21791.1
BAC25619.1
BAC34195.1
BAC35720.1
BAC39717.1
NP_598742.1
Q8BT44
Q8C378
Q8C7G0
Q8VDI9
 
 Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Pig-b;PigB) 2.4.1.- Mus musculus BAA94827.1
AAH52658.1
BAE32195.1
NP_061377.2
Q7TQ01
Q9JJQ0
 
 Alg12   Mus musculus FVB/N CAD22101.1
AAH21379.1
BAE25031.1
NP_663452.1
Q8VCA2
Q8VDB2
 
 unnamed protein product   Mus musculus NOD BAC40783.1
AAI17749.1
NP_766410.1
Q8BTP0  
 ORF (fragment)   Musca domestica ALHF AFP63317.1    
 ORF (fragment)   Mustela putorius furo AER94053.1    
 ORF (fragment)   Mustela putorius furo AER94054.1    
 ORF (fragment)   Mustela putorius furo AES04000.1    
 ORF (fragment)   Mustela putorius furo AER94043.1    
 ORF (fragment)   Mustela putorius furo AES04025.1    
 NCAS_0D00860   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC69667.1    
 NCAS_0G01440 (Ncas0g01440)   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC71031.1    
 NCAS_0H02350   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC71545.1    
 NCAS_0A05360   Naumovozyma castellii CBS 4309 type strain:CBS 4309 CCC67094.1    
 NDAI_0C01290 (Ndai0c01290)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD23790.1    
 NDAI_0F03720   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD25690.1    
 NDAI_0H03290 (Ndai0h03290)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD26502.1    
 NDAI_0K02210 (Ndai0k02210)   Naumovozyma dairenensis CBS 421 type strain:CBS 421 CCD27412.1    
 NCLIV_004260   Neospora caninum Liverpool CBZ49942.1    
 NCU04454.1 (G21B4.070)   Neurospora crassa OR74A CAF05992.1
XP_323807.1
Q7RWB2  
 NCU07472.1   Neurospora crassa OR74A XP_327758.1    
 NCU00193.1   Neurospora crassa OR74A XP_322279.1 Q7RX94  
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