GlycosylTransferase Family 22

Activities in FamilyDol-P-Man: Man6GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.259); Dol-P-Man: Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.261); Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-); Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-)
Mechanism Inverting
3D Structure StatusGT-C
NoteThese enzymes use dolichol-P-mannose as the sugar donor.
External resourcesGlymap; GPI:PIG-B; GPI:SMP3;
Statistics GenBank accession (1097); Uniprot accession (169);
All (928) Bacteria (54) Eukaryota (874) Characterized (9)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CORT_0G04380   Candida orthopsilosis Co 90-125 CCG25115.1    
 CPAR2_206670   Candida parapsilosis CDC317 CCE43024.1    
 CPAR2_211600   Candida parapsilosis CDC317 CCE43516.1    
 CPAR2_502650 (possible fragment)   Candida parapsilosis CDC317 CCE44040.1    
 CPAR2_704200   Candida parapsilosis CDC317 CCE45406.1    
 CGB_F5370W   Cryptococcus gattii WM276 ADV23102.1    
 CGB_C7370C   Cryptococcus gattii WM276 ADV21256.1    
 CGB_C5280C   Cryptococcus gattii WM276 ADV21113.1    
 CNAG_05881   Cryptococcus neoformans var. grubii H99 AFR96200.1    
 CNAG_07527 (fragment)   Cryptococcus neoformans var. grubii H99 AFR94003.1    
 CNAG_02715   Cryptococcus neoformans var. grubii H99 AFR93974.1
AFR93974.2
   
 CNAG_02892   Cryptococcus neoformans var. grubii H99 AFR93799.1
AFR93799.2
   
 CNC05050   Cryptococcus neoformans var. neoformans JEC21 AAW42717.1
AAW42717.2
Q5KJX3  
 CNF00920   Cryptococcus neoformans var. neoformans JEC21 AAW44364.1 Q5KFQ7  
 CNC03430   Cryptococcus neoformans var. neoformans JEC21 AAW42684.1 Q5KKD0  
 CYME_CMQ162C   Cyanidioschyzon merolae strain 10D BAM82065.1    
 CYFA0S_05e02674g   Cyberlindnera fabianii YJS4271 CDR40632.1    
 CYFA0S_07e04390g   Cyberlindnera fabianii YJS4271 CDR41631.1    
 CYFA0S_08e03048g   Cyberlindnera fabianii YJS4271 CDR42052.1    
 CYFA0S_02e03972g   Cyberlindnera fabianii YJS4271 CDR38638.1    
 ORF   Danio rerio AAH55191.1
NP_956770.1
Q7SXZ1  
 DKEY-71L1.4-001   Danio rerio CAN88585.1
AAH56834.1
NP_956919.1
A5PMV6  
 DKEY-164M14.3   Danio rerio CAI20715.1
AAI42933.1
CAI20714.1
Q5RFU6  
 ORF (fragment)   Dasypyrum villosum AER62269.1    
 ORF (fragment)   Dasypyrum villosum AER62277.1    
 DEHA2C17270g   Debaryomyces hansenii CBS767 CAR65594.1
CAG86523.1
   
 DEHA0C18535g (probable fragment)   Debaryomyces hansenii CBS767 CAG86522.1    
 DEHA2G04114g   Debaryomyces hansenii CBS767 CAR65907.1
CAG90177.1
Q6BJ96  
 DEHA2G21010g   Debaryomyces hansenii CBS767 CAR66012.1
CAG90966.1
Q6BH65  
 DEHA0C11880g   Debaryomyces hansenii CBS767 CAG86226.1 Q6BUG4  
 α-1,6-mannosyltransferase   Dendrobium catenatum AIR92102.1    
 unknown   Dendroctonus ponderosae AEE62059.1    
 Dbus_chr3Rg1651   Drosophila busckii ALC46901.1    
 Dbus_chr2Rg1468   Drosophila busckii ALC41889.1    
 Dbus_chr3Lg1067   Drosophila busckii ALC43901.1    
 Dbus_chr3Rg211   Drosophila busckii ALC45461.1    
 CG3419 (Smp3)   Drosophila melanogaster AAS64768.1
AAF47201.1
AAM48349.1
AHN56635.1
NP_611909.1
Q8MT80  
 CG12006 (Gpi10)   Drosophila melanogaster AAF47795.2
AAO24997.1
AAS64961.1
NP_647832.1
Q9VZM5  
 CG8412   Drosophila melanogaster AAF54441.1
AAL48754.1
NP_649939.1
Q9VH78  
 CG11851   Drosophila melanogaster AAF56419.1
AAL39788.1
NP_651353.1
Q9VBV8  
 ORF (fragment)   Elymus libanoticus AER62272.1    
 ORF (fragment)   Elymus libanoticus AER62291.1    
 ORF (fragment)   Elymus spicatus AER62274.1    
 ORF (fragment)   Equus caballus AEH58176.1    
 ORF (fragment)   Equus caballus AEQ00108.1    
 ORF (fragment)   Eremopyrum bonaepartis AER62280.1    
 ORF (fragment)   Eremopyrum triticeum AER62282.1    
 Ecym_2496   Eremothecium cymbalariae DBVPG#7215 AET38218.1    
 Ecym_3374   Eremothecium cymbalariae DBVPG#7215 AET38861.1    
 Ecym_4547   Eremothecium cymbalariae DBVPG#7215 AET39582.1    
 Ecym_6468   Eremothecium cymbalariae DBVPG#7215 AET40839.1    
 AAR043C   Eremothecium gossypii ATCC 10895 AAS50408.1 Q75EN6  
 ADL281C   Eremothecium gossypii ATCC 10895 AAS51639.1 Q75BG9  
 AFR395C   Eremothecium gossypii ATCC 10895 AAS53766.2
AAS53766.1
Q753C1  
 ABL185C   Eremothecium gossypii ATCC 10895 AAS50586.1 Q75E55  
 FAGOS_FABL185C   Eremothecium gossypii FDAG1 AEY94874.1    
 FAGOS_FAFR395C   Eremothecium gossypii FDAG1 AEY98078.1    
 FAGOS_FADL281C   Eremothecium gossypii FDAG1 AEY95935.1    
 FAGOS_FAAR043C   Eremothecium gossypii FDAG1 AEY94694.1    
 AW171_hschr84740   Eremothecium sinecaudum ATCC 58844 AMD22689.1    
 AW171_hschr31923   Eremothecium sinecaudum ATCC 58844 AMD20053.1    
 AW171_hschr63662   Eremothecium sinecaudum ATCC 58844 AMD21693.1    
 AW171_hschr21267   Eremothecium sinecaudum ATCC 58844 AMD19437.1    
 FFUJ_02943   Fusarium fujikuroi IMI 58289 CCT65953.1    
 FFUJ_08677   Fusarium fujikuroi IMI 58289 CCT71266.1    
 FFUJ_01427   Fusarium fujikuroi IMI 58289 CCT63406.1    
 FFUJ_04901   Fusarium fujikuroi IMI 58289 CCT63927.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF84110.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF86733.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF88256.1    
 FGRAMPH1_01T03053   Fusarium graminearum PH-1 SCB64206.1
CEF73328.1
   
 RCJMB04_1n22 (fragment)   Gallus gallus CAG31051.1 Q5ZMJ2  
 Wrky25   Gossypium hirsutum AIE43865.1    
 ORF (fragment)   Henrardia persica AER62283.1    
 ORF (fragment)   Henrardia persica AER62284.1    
 ORF (fragment)   Heteranthelium piliferum AER62273.1    
 Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (PigB;Pig-B) 2.4.1.- Homo sapiens BAA07709.1
AAH17711.1
ACM85135.1
BAD97050.1
BAG37253.1
BAG57112.1
CAH05352.1
CAH05365.1
CAH05366.1
NP_004846.3
Q8WVN7
Q92521
 
 Dol-P-Man: Man6GlcNAc2-PP-Dol/Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (Alg9;DIBD1;DKFZp586M2420;FLJ21845) 2.4.1.259
2.4.1.261
Homo sapiens BAB15154.1
AAH09255.1
AAL25798.1
AAP97696.1
BAD18793.1
BAG60945.1
BAG63872.1
CAB66861.1
NP_079016.1
XP_041331.1
Q6ZMD5
Q9H6U8
 
  Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Smp3;Pig-Z) 2.4.1.- Homo sapiens BAB14263.1
AAH44640.1
BAG59430.1
CAE90685.1
NP_079439.2
XP_016392.1
XP_067596.1
Q86VD9
Q9H9G6
 
 Dol-P-Man: Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase (Alg12;PP14673) 2.4.1.260 Homo sapiens AAH01729.1
AAH98562.1
AAL55850.1
AAM94900.1
CAC67488.1
CAC83681.1
CAG30255.1
CAO72064.1
NP_077010.1
Q9BV10
Q9BV10
 
 ORF (fragment)   Hordeum bogdanii AER62286.1    
 ORF (fragment)   Hordeum marinum subsp. marinum AER62287.1    
 ORF (fragment)   Hordeum vulgare subsp. spontaneum AER62264.1    
 predicted protein (fragment)   Hordeum vulgare subsp. vulgare BAJ97682.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56562.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56598.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56550.1    
 ORF   Hypocrella siamensis MTCC 10142 ANH56590.1    
 KAFR_0A07890 (Kafr0a07890)   Kazachstania africana CBS 2517 CCF56223.1    
 KAFR_0B04770 (Kafr0b04770)   Kazachstania africana CBS 2517 CCF56774.1    
 KAFR_0C04580 (Kafr0c04580)   Kazachstania africana CBS 2517 CCF57449.1    
 KAFR_0E03570 (Kafr0e03570)   Kazachstania africana CBS 2517 CCF58508.1    
 KNAG_0C04580 (Knag0c04580)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK69560.1    
 KNAG_0D00400 (Knag0d00400)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK69793.1    
 KNAG_0F00920 (Knag0f00920)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK70761.1    
 KNAG_0I00730 (Knag0i00730)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK71864.1    
 KLLA0C06567g   Kluyveromyces lactis NRRL Y-1140 CAH01341.1 Q6CU99  
 KLLA0D19404g   Kluyveromyces lactis NRRL Y-1140 CAH01019.1 Q6CQ66  
 KLLA0E14762g   Kluyveromyces lactis NRRL Y-1140 CAG99700.1 Q6CN76  
 KLLA0C08591g   Kluyveromyces lactis NRRL Y-1140 CAH01434.1 Q6CU06  
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