| Known Activities | Dol-P-Man α-mannosyltransferase (EC 2.4.1.-) |
|---|---|
| Mechanism | Inverting |
| 3D Structure Status | GT-C |
| Note | These enzymes use dolichol-P-mannose as the sugar donor. |
| External resources | GPI:PIG-B; GPI:SMP3; PFAM; |
| Statistics | GenBank accession (437); Uniprot accession (136); |
| Eukaryota | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Smp3;Pig-Z) | 2.4.1.- | Homo sapiens | AAH44640.1 BAB14263.1 BAG59430.1 CAE90685.1 NP_079439.2 XP_016392.1 XP_067596.1 |
Q86VD9 Q9H9G6 |
||
| Pig-b (PigB) | 2.4.1.- | Mus musculus | AAH52658.1 BAA94827.1 BAE32195.1 NP_061377.2 |
Q7TQ01 Q9JJQ0 |
||
| Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Smp3;YOR149c) | 2.4.1.- | Saccharomyces cerevisiae S288c | AAC49635.1 CAA41123.1 CAA99355.1 NP_014792.1 |
Q04174.2 | ||
| dolichyl-phosphate-mannose α-1,2-mannosyltransferase (Alg9;YNL219c;N1295) | 2.4.1.- | Saccharomyces cerevisiae S288c | CAA65277.1 CAA96122.1 NP_014180.1 |
P53868 | ||
| Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Gpi10;Per13;YGL142c) | 2.4.1.- | Saccharomyces cerevisiae S288c | CAA42931.1 CAA68220.1 CAA96854.1 NP_011373.1 |
P30777.2 | ||
| Dol-P-Man: Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase (Alg12;Tb927.2.4720) | 2.4.1.- | Trypanosoma brucei | AAQ15930.1 AAX80168.1 |
Q586R8 Q7YUW0 |
||
Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.