GlycosylTransferase Family 22

Activities in FamilyDol-P-Man: Man6GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.259); Dol-P-Man: Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (EC 2.4.1.261); Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-); Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (EC 2.4.1.-)
Mechanism Inverting
3D Structure StatusGT-C
NoteThese enzymes use dolichol-P-mannose as the sugar donor.
External resourcesGlymap; GPI:PIG-B; GPI:SMP3;
Statistics GenBank accession (1097); Uniprot accession (169);
All (928) Bacteria (54) Eukaryota (874) Characterized (9)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (PigB;Pig-B) 2.4.1.- Homo sapiens BAA07709.1
AAH17711.1
ACM85135.1
BAD97050.1
BAG37253.1
BAG57112.1
CAH05352.1
CAH05365.1
CAH05366.1
NP_004846.3
Q8WVN7
Q92521
 
 Dol-P-Man: Man6GlcNAc2-PP-Dol/Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (Alg9;DIBD1;DKFZp586M2420;FLJ21845) 2.4.1.259
2.4.1.261
Homo sapiens BAB15154.1
AAH09255.1
AAL25798.1
AAP97696.1
BAD18793.1
BAG60945.1
BAG63872.1
CAB66861.1
NP_079016.1
XP_041331.1
Q6ZMD5
Q9H6U8
 
  Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Smp3;Pig-Z) 2.4.1.- Homo sapiens BAB14263.1
AAH44640.1
BAG59430.1
CAE90685.1
NP_079439.2
XP_016392.1
XP_067596.1
Q86VD9
Q9H9G6
 
 Dol-P-Man: Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase (Alg12;PP14673) 2.4.1.260 Homo sapiens AAH01729.1
AAH98562.1
AAL55850.1
AAM94900.1
CAC67488.1
CAC83681.1
CAG30255.1
CAO72064.1
NP_077010.1
Q9BV10
Q9BV10
 
 Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Pig-b;PigB) 2.4.1.- Mus musculus BAA94827.1
AAH52658.1
BAE32195.1
NP_061377.2
Q7TQ01
Q9JJQ0
 
 Dol-P-Man: Man3-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Smp3;YOR149c) 2.4.1.- Saccharomyces cerevisiae S288c AAC49635.1
CAA41123.1
CAA99355.1
NP_014792.1
Q04174  
 Dol-P-Man: Man6GlcNAc2-PP-Dol/Man8GlcNAc2-PP-Dol α-1,2-mannosyltransferase (Alg9;YNL219c;N1295) 2.4.1.259
2.4.1.261
Saccharomyces cerevisiae S288c CAA65277.1
CAA96122.1
NP_014180.1
P53868  
 Dol-P-Man: Man2-GlcNAc-phosphatidylinositol α-1,2-mannosyltransferase (Gpi10;Per13;YGL142c) 2.4.1.- Saccharomyces cerevisiae S288c CAA68220.1
CAA42931.1
CAA96854.1
NP_011373.1
P30777  
 Dol-P-Man: Man7GlcNAc2-PP-Dol α-1,6-mannosyltransferase (Alg12;Tb927.2.4720) 2.4.1.260 Trypanosoma brucei AAQ15930.1
AAX80168.1
Q586R8
Q7YUW0
 
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