GlycosylTransferase Family 21

Known Activities	UDP-Glc: ceramide β-glucosyltransferase (EC 2.4.1.80).
Mechanism	Inverting
3D Structure Status	GT-A
Note	Distant similarity to families GT2, GT12 and GT27
External resources	CFG(Glycosphingolipid);
Statistics	GenBank accession (328); Uniprot accession (193);

Summary

All (263) Archaea (15) Bacteria (190) Eukaryota (57) unclassified (1) Characterized (12)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
lipid β-galactosyltransferase / β-glucosyltransferase (Atu1808;UgcG)	2.4.1.-	Agrobacterium tumefaciens str. C58	AAK87577.1 AAK87577.2 AAL42806.1 NP_354792.1 NP_532490.1	Q7CYH2 Q8UEF0
lipid β-galactosyltransferase / β-glucosyltransferase (Mlr5650)	2.4.1.-	Mesorhizobium loti MAFF303099	BAB52059.1 NP_106273.1	Q98BB3
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
UDP-Glc: glucosylceramide synthase (F20B4.6)	2.4.1.80	Caenorhabditis elegans Bristol N2	AAC48147.3 AAK73018.1 CCD69753.1 NP_510857.2	Q19624
UDP-Glc: glucosylceramide synthase (Cgt-3;F59G1.1)	2.4.1.80	Caenorhabditis elegans Bristol N2	AAC71156.1 AAK31528.1 AAK31533.1 AAL32224.1 AAL32225.1 AAM15582.1 AAO38632.1 ABD75711.1 ABD75712.1 ABD75713.1 CCD70149.1 CCD70150.1 CCD70151.1 CCD70152.1 NP_495181.2 NP_495182.2 NP_741005.1 NP_871996.1	Q21054 Q86NG8 Q8T3D8 Q9BI83
UDP-Glc: ceramide β-glucosyltransferase	2.4.1.80	Gossypium arboreum	AAK73021.1	Q946Y1
UDP-Glc: ceramide glucosyltransferase (UGCG)	2.4.1.80	Homo sapiens	AAH38711.1 ACM83968.1 BAA09451.1 CAI15902.1 NP_003349.1	Q16739 Q5T258
UDP-Glc: ceramide glucosyltransferase (MG10668.4)	2.4.1.80	Magnaporthe grisea 70-15	AAK73019.1 XP_366450.1
UDP-Glc: ceramide glucosyltransferase (GCS;CGT;Ugcg;Glct-1)	2.4.1.80	Mus musculus	AAH50828.1 BAA28782.1 BAA33558.1 CAM26180.1 NP_035803.1	A2AN90 O88693.1
UDP-Glc: ceramide glucosyltransferase (PAS_chr3_0357)	2.4.1.80	Pichia pastoris GS115	AAK73020.1 CAY70399.1	C4R4B3 Q96V37
Gcs1 (PcGCS1)	2.4.1.-	Pneumocystis carinii	AAK13500.1	Q9C3Y5
UDP-Glc: ceramide glucosyl transferase (UgcG)	2.4.1.80	Rattus norvegicus	AAD02464.1 CAA11853.1 NP_113983.1	Q9R0E0.1
UDP-Glc: ceramide glucosyltransferase (Cgt;LOC495444)	2.4.1.80	Xenopus laevis	AAH84966.1 AAH89245.1 AAM49061.1	Q8AY29

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.