GlycosylTransferase Family 20

Activities in Familyα,α-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15); Glucosylglycerol-phosphate synthase (EC 2.4.1.213); trehalose-6-P phosphatase (EC 3.1.3.12); [retaining] GDP-valeniol: validamine 7-phosphate valeniolyltransferase (EC 2.-.-.-)
Mechanism Retaining
3D Structure StatusGT-B
Statistics GenBank accession (5824); Uniprot accession (760); PDB accession (30); 3D entries (12); cryst (0)
All (5107) Archaea (63) Bacteria (3987) Eukaryota (1055) unclassified (2) Structure (12) Characterized (52)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 Bmul_0897 (OtsA)   Burkholderia multivorans ATCC 17616 ABX14591.1
BAG44255.1
A9AIF6
5UOF[A,B] 1.70
 Bcep1808_2483   Burkholderia vietnamiensis G4 ABO55481.1 A4JGS8
5TVG[A,B,C,D,E,F,G,H] 2.30
 α,α-trehalose-phosphate synthase (OtsA;Tps;b1896) 2.4.1.15 Escherichia coli str. K-12 substr. MG1655 AIZ91009.1
AAA68604.1
AAC74966.1
AAE52301.1
AAN95312.1
AAW99267.1
ACI81904.1
ACO57635.1
ALI40335.1
AMC94875.1
CAA48913.1
CAB42256.1
CAB58460.1
CAB58465.1
CBF70287.1
CBG04443.1
NP_416410.1
P31677
1GZ5[A] P-(0-6)-α-D-Glcp
2.43
1UQT[A] 2.0
1UQU[A] 2.0
2WTX[A,B,C,D] <carb_like_VDO>
2.20
 α,α-trehalose-6-phosphate synthase (RMCT_1906) 2.4.1.15 Mycobacterium thermoresistibile WP_003926306.1  
5JIJ[A] 1.82
5JIO[A] P-(0-6)-α-D-Glcp
1.71
5K41[A] 1.97
5K42[A] 1.92
5K44[A] 1.93
5K5C[A] α-D-Glcp-(1-1)-α-D-Glcp
1.85
5L3K[A,B,C,D,E,F,G,H] P-(0-6)-β-D-Fruf
2.31
 α,α-trehalose-phosphate synthase (Bxe_A3374)   Paraburkholderia xenovorans LB400 ABE29611.1 Q142X8
5HXA[A] 2.00
 α,α-trehalose-phosphate synthase (Bxe_A1242)   Paraburkholderia xenovorans LB400 ABE31711.1 Q13W28
5V0T[A,B,C,D,E,F,G,H] P-(0-6)-α-D-Glcp
1.95
 GDP-valeniol: validamine 7-phosphate valeniolyltransferase (ValL;VldE) 2.-.-.- Streptomyces hygroscopicus subsp. limoneus KCCM 11405 ABC67269.1 Q15JG1
3T5T[A,B] 1.70
3T7D[A,B] α-D-Glcp-(1-1)-α-D-Glcp
1.70
3VDM[A,B] 1.98
3VDN[B] 2.55
4F96[A,B] 2.15
4F97[A,B] <carb_like_VDO>
2.11
4F9F[A,B,C,D,E,F] α-D-Glcp-(1-1)-α-D-Glcp
2.81
 trehalose-6-phosphate synthase (OtsA;SVEN_4043) 2.4.1.15 Streptomyces venezuelae ATCC 10712 CCA57329.1  
5LQD[A,B,C,D] 1.95
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 trehalose-6-phosphate synthase A (AFUA_6G12950)   Aspergillus fumigatus Af293 EAL89135.1  
5HVM[A,B] <carb_like_VDM>
2.82
 trehalose-6-phosphate synthase B (AFUA_2G04010)   Aspergillus fumigatus Af293 EAL87495.1  
5HVO[A,B,C,D] <carb_like_VDM>
2.47
 trehalose-6-phosphate phosphatase (Tps2) 3.1.3.12 Candida albicans CAC17748.1 G1UAE0
Q5AI14
5DXF[A,B] 2.56
 α,α-trehalose-phosphate synthase (Tps1; CAALFM_CR05720WA) 2.4.1.15 Candida albicans SC5314 AOW31288.1
AAV05161.1
CAA69223.1
CBF70450.1
CBF98938.1
C4YM18
Q92410
5HUT[A,B] 1.90
5HUU[A,B] P-(0-6)-α-D-Glcp
2.37
5HUV[A,B] 2.00
5HVL[A,B] <carb_like_VDM>
1.80
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