GlycosylTransferase Family 20

Activities in Familyα,α-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15); Glucosylglycerol-phosphate synthase (EC 2.4.1.213); trehalose-6-P phosphatase (EC 3.1.3.12); [retaining] GDP-valeniol: validamine 7-phosphate valeniolyltransferase (EC 2.-.-.-)
Mechanism Retaining
3D Structure StatusGT-B
Statistics GenBank accession (13229); Uniprot accession (68); PDB accession (35); 3D entries (14); cryst (0)
Archaea
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 trehalose-6-phosphate synthase (Ta1210) 2.4.1.15   Thermoplasma acidophilum DSM 1728 CAC12335.1
CBF70433.1
CBF98930.1
NP_394666.1
Q9HIW6  
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 trehalose-6-P synthase (TpS1) 2.4.1.15   Actinoplanes sp. SN223/29 ABV26721.1 A8QX04  
 Trehalose-6-phosphate synthase 2.4.1.15   Escherichia coli NCTC9077_02568   P31677 6JAK[A,B,C,D]
6JAK[nd]
 α,α-trehalose-phosphate synthase (OtsA;Tps;b1896) 2.4.1.15   Escherichia coli str. K-12 substr. MG1655 AIZ91009.1
AAA68604.1
AAC74966.1
AAE52301.1
AAN95312.1
AAW99267.1
ACI81904.1
ACO57635.1
ALI40335.1
AMC94875.1
AUG16661.1
AVI56412.1
AYG19054.1
CAA48913.1
CAB42256.1
CAB58460.1
CAB58465.1
CBF70287.1
CBG04443.1
NP_416410.1
P31677
Q6PQ82
1GZ5[A]
1UQT[A]
1UQU[A]
2WTX[A,B,C,D]
 trehalose-phosphate synthase (TreS) 2.4.1.15   Meiothermus ruber CBS-01 ACJ06397.1 B6VB02  
 trehalose-6-P synthase (Rv3490;OtsA) 2.4.1.15   Mycobacterium tuberculosis H37Rv CAB08713.1
AAY73024.1
AFN51508.1
CBF70302.1
CBG04450.1
CCP46312.1
NP_218007.1
O06353
P9WN11
 
 α,α-trehalose-6-P synthase (OtsA;MSMEG_5892) 2.4.1.15   Mycolicibacterium smegmatis MC2 155 ABK71484.1
AFP42165.1
AIU10894.1
A0R4M9  
 α,α-trehalose-6-phosphate synthase (RMCT_1906) 2.4.1.15   Mycolicibacterium thermoresistibile WP_003926306.1 A0A117IMA6
G7CGT2
5JIJ[A]
5JIO[A]
5K41[A]
5K42[A]
5K44[A]
5K5C[A]
5L3K[A,B,C,D,E,F,G,H]
 trehalose-6-phosphate synthase (OtsA;Tps) 2.4.1.15   Propionibacterium freudenreichii subsp. shermanii NIZO B365 ABC88237.1
AAV63796.1
A1XGA8  
 trehalose-6-phosphate synthase (OtsA;Tps) 2.4.1.15   Pseudomonas savastanoi BCNU 106 AAQ76839.1 Q6JTB2  
 RSp0731 2.4.1.15   Ralstonia solanacearum GMI1000 CAD17882.1
NP_522292.1
Q8XRV0  
 trehalose-6-phosphate synthase 2.4.1.15   Rhizobium etli AAU12353.1 Q66Q98  
 RHE_CH00476 (OtsA) 2.4.1.15   Rhizobium etli CFN 42 ABC89297.1 Q2KCY9  
 α,α-trehalose-6P synthase (Tps;Rxyl_2972) 2.4.1.15   Rubrobacter xylanophilus DSM 9941 ABG05882.1
ACJ76776.1
B8R7Q2
Q1ARU6
 
 glucosylglycerol-phosphate phosphatase/synthase (GgppS;GgpS) 2.4.1.213   Stenotrophomonas rhizophila DSM 14405 CAI47795.2 Q5GMP2  
 GDP-valeniol: validamine 7-phosphate valeniolyltransferase (ValL;VldE) 2.-.-.-   Streptomyces hygroscopicus subsp. limoneus KCCM 11405 ABC67269.1 H2K885
Q15JG1
3T5T[A,B]
3T7D[A,B]
3VDM[A,B]
3VDN[B]
4F96[A,B]
4F97[A,B]
4F9F[A,B,C,D,E,F]
 trehalose-6-phosphate synthase (OtsA;SVEN_4043) 2.4.1.15   Streptomyces venezuelae ATCC 10712 CCA57329.1
QES00438.1
F2RH01 5LQD[A,B,C,D]
 trehalose-phosphate synthase (OtsA) 2.4.1.15   Thermus thermophilus RQ-1 AAQ16095.1
CBF70390.1
CBF98909.1
Q7WUI7  
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 At1g70290 (trehalose-6-phosphate synthase 2;Tps2) 2.4.1.15   Arabidopsis thaliana AAC18810.1
AAO15311.1
AEE35042.1
AID66008.1
ANM58788.1
BAE99209.1
NP_177186.1
A0A068FL15
A0A1P8AQ69
Q0WUI9
 
 At1g60140 (trehalose-6-phosphate synthase 3;Tps3) 2.4.1.15   Arabidopsis thaliana AAC24048.1
AAO15312.1
AEE33662.1
AHL38899.1
ANM60414.1
ANM60415.1
ANM60416.1
ANM60417.1
ANM60418.1
BAF01061.1
CBF70314.1
CBG04456.1
NP_176221.1
A0A1P8AUV4
A0A654EL48
O80738
W8Q795
 
 α,α-trehalose-6-phosphate synthase (Tps1;AtTPS1;At1g78580) 2.4.1.15   Arabidopsis thaliana AAD30578.1
AAK44102.2
AAL34229.1
AAW99275.1
ACX05732.1
AEE36123.1
AHL38866.1
ANM60660.1
ANM60661.1
ANM60662.1
CAA69879.1
CAB42266.1
CBF70295.1
CBG04447.1
NP_177979.1
A0A384L3B9
P93653
Q94K55
Q9SYM4
W8PVS8
 
 α,α-trehalose-phosphate synthase (TpsA;AN5523.2) 2.4.1.15   Aspergillus nidulans FGSC A4 EAA62683.1
AAC18060.1
CBF70452.1
CBF98939.1
C8VG92
O59921
 
 α,α-trehalose-phosphate synthase (TpsA;Tps1) 2.4.1.15   Aspergillus niger ATCC 11414 AAA21861.1
AAN95309.1
CBF70465.1
CBF98945.1
Q00075  
 α,α-trehalose-phosphate synthase (TpsB) 2.4.1.15   Aspergillus niger ATCC 11414 AAB05869.1 Q00217  
 An07g08710 (TpsB) 2.4.1.15   Aspergillus niger CBS 513.88 CAK39664.1 A2QP99  
 An08g10510 (TpsA) 2.4.1.15   Aspergillus niger CBS 513.88 CAK45724.1 A2QSF2  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15   Botrytis cinerea B05.10 ABG25558.1 A0A384JAD8
Q156F5
 
 trehalose-6-phosphate phosphatase (Tps2) 3.1.3.12   Candida albicans CAC17748.1 G1UAE0
Q5AI14
5DXF[A,B]
 α,α-trehalose-phosphate synthase (Tps1; CAALFM_CR05720WA) 2.4.1.15   Candida albicans SC5314 AOW31288.1
AAV05161.1
CAA69223.1
CBF70450.1
CBF98938.1
C4YM18
Q92410
5HUT[A,B]
5HUU[A,B]
5HUV[A,B]
5HVL[A,B]
 trehalose-6-phosphate synthase (Tps;CfTPS) 2.4.1.15   Ctenocephalides felis AFP67548.1 J7G8S5  
 trehalose-6-phosphate synthase (Tps1;CG4104;Dmel_CG4104) 2.4.1.15   Drosophila melanogaster AAD38628.1
AAF51020.1
AAX33476.1
ABH06624.1
ABH06625.1
ABH06626.1
ABH06627.1
ABH06628.1
ABH06629.1
ABH06630.1
ABH06631.1
ABH06632.1
ABH06633.1
ABH06634.1
ABH06635.1
ABH06636.1
ABH06637.1
ABH06638.1
ABH06639.1
ABH06640.1
ABH06641.1
CBF70442.1
CBF98934.1
NP_608827.1
Q9Y119  
 trehalose 6-phosphate synthase (Tps) 2.4.1.15   Helicoverpa armigera ACH88521.1
AAY87162.2
B5TD29
Q4JHW9
 
 α,α-trehalose-phosphate synthase (Tps1;Ggs1) 2.4.1.15   Kluyveromyces lactis ATCC 8585 CAA51164.1
AAN95307.1
CBF70308.1
CBG04453.1
Q07158  
 trehalose-6-P synthase 1 (Tps1) 2.4.1.15   Metarhizium acridum CQMA102 AAX55633.1 Q58FS5  
 α,α-trehalose-6-phosphate synthase 1 (Tps1;OsTPS1) 2.4.1.15   Oryza sativa Indica Group AEB53177.1 H6ST13  
 trehalose-6-P synthase (Tps1;SNOG_09603;SNU09603.1) (17486) 2.4.1.15   Parastagonospora nodorum SN15 EAT82868.2 Q0UF61  
 α,α-trehalose-phosphate synthase (Tps1) 2.4.1.15   Pichia angusta AAX06612.1
CAB38058.1
CBF70454.1
CBF98940.1
O94213  
 trehalose phosphate synthase (Tps3) 2.4.1.15   Pichia angusta CBS4731 AAF73139.1 Q9P918  
 trehalose-6-phosphate synthase subunit 1 (TPS1) 2.4.1.15   Pyricularia grisea GUY11 AAN46744.1
CBF70394.1
CBF98911.1
Q875L7  
 trehalose-6-phosphate synthase (MG03860.4) 2.4.1.15   Pyricularia oryzae 70-15 XP_361386.1 G4NHF4 6JBI[A,B]
6JBR[A,B,D,F,H,K,M,O]
6JBW[A,B]
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15   Saccharomyces cerevisiae AS2.1416 AAC16974.1 G4XSR1
Q00764
 
 trehalose-6-phosphate synthase (Tps1;Cif1) 2.4.1.15   Saccharomyces cerevisiae C836 CAA43580.1
AAE24073.1
AAO30562.1
G4XSR1
Q00764
 
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15   Saccharomyces cerevisiae FHS AAT27374.1 G4XSR1
Q00764
 
 α,α-trehalose-phosphate synthase (Tsl1;YML100w) 2.4.1.15   Saccharomyces cerevisiae S288c AAO30641.1
CAA51303.1
CAA56797.1
CBF70306.1
CBG04452.1
NP_013608.1
P38427  
 α,α-trehalose-6-phosphate synthase (Tps1;Cif1;Byp1;Fdp1;Ggs1;Glc6;ScTPS1;YBR126c;YBR0922) 2.4.1.15   Saccharomyces cerevisiae S288c AAA53672.1
AAN95308.1
AAT93166.1
ABL11219.1
AEP68447.1
AEP68448.1
AEP68449.1
AEP68450.1
AEP68451.1
AEP68452.1
AEP68453.1
AEP68454.1
AEP68455.1
AEP68457.1
AEP68458.1
AEP68459.1
AEP68460.1
AEP68461.1
AEP68462.1
AEP68464.1
AEP68469.1
AEP68471.1
AEP68472.1
AEP68473.1
AEP68474.1
AEP68475.1
AEP68476.1
AEP68477.1
AEP68478.1
AEP68479.1
AEP68480.1
AEP68481.1
AEP68482.1
AEP68483.1
AEP68484.1
AEP68485.1
AEP68486.1
AEP68487.1
AEP68488.1
AEP68489.1
AEP68490.1
AEP68491.1
AEP68492.1
AEP68493.1
AEP68494.1
AEP68495.1
AEP68496.1
AEP68497.1
AEP68498.1
AEP68499.1
AEP68500.1
AEP68501.1
AEP68503.1
AEP68504.1
AEP68505.1
AEP68506.1
AEP68507.1
AEP68508.1
AEP68510.1
AEP68511.1
AEP68512.1
AEP68513.1
AEP68514.1
AEP68515.1
AEP68516.1
AEP68517.1
AEP68518.1
AEP68519.1
AGJ95103.1
CAA47834.1
CAA48510.1
CAA53485.1
CAA85083.1
CBF70304.1
CBG04451.1
NP_009684.1
E9P9E3
G4XSR1
Q00764
 
 α,α-trehalose-phosphate synthase (Tps3;YMR261c;YM8156.03C) 2.4.1.15   Saccharomyces cerevisiae S288c AAT92987.1
AAA35224.1
CAA89244.1
NP_013988.1
P38426  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15   Saccharomyces cerevisiae WFB AAT27376.1 G4XSR1
Q00764
 
 trehalose-6-P synthase (Tps1) 2.4.1.15   Saccharomycopsis fibuligera A11 ABD47524.2
ABD47524.1
ADQ43750.1
Q27V66  
 α,α-trehalose-phosphate synthase (Tps1;SPAC328.03) 2.4.1.15   Schizosaccharomyces pombe 972h- CAB95998.1
AAN95310.1
CAA82861.1
CBF70327.1
CBF70456.1
CBF98941.1
CBG04462.1
NP_594205.1
P40387  
 α,α-trehalose-phosphate synthase (Tps;SlTPS) 2.4.1.15   Selaginella lepidophylla AAD00829.1
CAB69548.1
CAB69549.1
CBF70333.1
CBG04465.1
Q9ZR75  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15   Selaginella pulvinata ADD71944.1 E7BK36  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15   Zygosaccharomyces rouxii KACC30010 AAK69413.1
CBF70460.1
CBF98943.1
Q96WK6  
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