GlycosylTransferase Family 20

Known Activitiesα,α-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15)
Mechanism Retaining
3D Structure StatusGT-B
External resourcesInterPro; PFAM;
Statistics GenBank accession (1562); Uniprot accession (719); PDB accession (4); 3D entries (1); cryst (0)
All (1106) Archaea (30) Bacteria (733) Eukaryota (341) unclassified (2) Structure (1 ) Characterized (47)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 trehalose-6-P synthase (TpS1) 2.4.1.15 Actinoplanes sp. SN223/29 ABV26721.1 A8QX04  
 α,α-trehalose-phosphate synthase (OtsA;b1896) 2.4.1.15 Escherichia coli K-12 MG1655 AAA68604.1
AAC74966.1
AAE52301.1
AAN95312.1
AAW99267.1
ACI81904.1
ACO57635.1
CAA48913.1
CAB42256.1
CAB58460.1
CAB58465.1
CAU97936.1
CBF70287.1
CBG04443.1
NP_416410.1
P31677.3 1GZ5[A]
1UQT[A]
1UQU[A]
2WTX[A,B,C,D]
 trehalose-phosphate synthase (TreS) 2.4.1.15 Meiothermus ruber CBS-01 ACJ06397.1 B6VB02  
 α,α-trehalose-6-P synthase (OtsA;MSMEG_5892) 2.4.1.15 Mycobacterium smegmatis str. MC2 155 ABK71484.1 A0R4M9  
 trehalose-6-P synthase (Rv3490;OtsA) 2.4.1.15 Mycobacterium tuberculosis H37Rv AAY73024.1
CAB08713.1
CBF70302.1
CBG04450.1
NP_218007.1
O06353  
 trehalose-6-phosphate synthase (OtsA;Tps) 2.4.1.15 Propionibacterium freudenreichii subsp. shermanii NIZO B365 AAV63796.1
ABC88237.1
A1XGA8  
 trehalose-6-phosphate synthase (OtsA;Tps) 2.4.1.15 Pseudomonas savastanoi BCNU 106 AAQ76839.1 Q6JTB2  
 RSp0731 2.4.1.15 Ralstonia solanacearum GMI1000 CAD17882.1
NP_522292.1
Q8XRV0  
 trehalose-6-phosphate synthase 2.4.1.15 Rhizobium etli AAU12353.1 Q66Q98  
 RHE_CH00476 (OtsA) 2.4.1.15 Rhizobium etli CFN 42 ABC89297.1 Q2KCY9  
 α,α-trehalose-6P synthase (Tps;Rxyl_2972) 2.4.1.15 Rubrobacter xylanophilus DSM 9941 ABG05882.1
ACJ76776.1
Q1ARU6  
 glucosylglycerol-phosphate phosphatase/synthase (GgppS;GgpS) 2.4.1.213 Stenotrophomonas rhizophila DSM 14405 CAI47795.2 Q5GMP2  
 α,α-trehalose-6-phosphate synthase (SalC) 2.4.1.15 Streptomyces albus ATCC 21838 ABN43206.1 A3FKK3  
 UDP-Glc: validoxylamine A α-glucosyltransferase / validamycin A synthase (VldE) 2.4.1.- Streptomyces hygroscopicus subsp. limoneus KCCM 11405 ABC67269.1 Q15JG1  
 trehalose-phosphate synthase (OtsA) 2.4.1.15 Thermus thermophilus RQ-1 AAQ16095.1
CBF70390.1
CBF98909.1
Q7WUI7  
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 At1g70290 (trehalose-6-phosphate synthase 2;Tps2) 2.4.1.15 Arabidopsis thaliana AAC18810.1
AAO15311.1
AEE35042.1
BAE99209.1
NP_177186.1
Q0WUI9  
 At1g60140 (trehalose-6-phosphate synthase 3;Tps3) 2.4.1.15 Arabidopsis thaliana AAC24048.1
AAO15312.1
AEE33662.1
BAF01061.1
CBF70314.1
CBG04456.1
NP_176221.1
O80738.1  
 At1g78580 (Trehalose-6-phosphate synthase;Tps1) 2.4.1.15 Arabidopsis thaliana AAD30578.1
AAK44102.2
AAL34229.1
AAW99275.1
ACX05732.1
AEE36123.1
CAA69879.1
CAB42266.1
CBF70295.1
CBG04447.1
NP_177979.1
P93653
Q94K55
Q9SYM4
 
 α,α-trehalose-phosphate synthase (TpsA;AN5523.2) 2.4.1.15 Aspergillus nidulans FGSC A4 AAC18060.1
CBF70452.1
CBF98939.1
EAA62683.1
C8VG92
O59921.1
 
 α,α-trehalose-phosphate synthase (TpsA;Tps1) 2.4.1.15 Aspergillus niger ATCC 11414 AAA21861.1
AAN95309.1
CBF70465.1
CBF98945.1
Q00075  
 α,α-trehalose-phosphate synthase (TpsB) 2.4.1.15 Aspergillus niger ATCC 11414 AAB05869.1 Q00217  
 An07g08710 (TpsB) 2.4.1.15 Aspergillus niger CBS 513.88 CAK39664.1 A2QP99  
 An08g10510 (TpsA) 2.4.1.15 Aspergillus niger CBS 513.88 CAK45724.1 A2QSF2  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15 Botryotinia fuckeliana B05.10 ABG25558.1 Q156F5  
 α,α-trehalose-phosphate synthase (Tps1) 2.4.1.15 Candida albicans AAV05161.1
CAA69223.1
CBF70450.1
CBF98938.1
C4YM18
Q92410
 
 trehalose-6-phosphate phosphatase (Tps2) 3.1.3.12 Candida albicans CAC17748.1 Q5AI14  
 α,α-trehalose-phosphate synthase (TPS1) 2.4.1.15 Cryptococcus neoformans var. grubii H99 AAT40476.1    
 trehalose 6-phosphate synthase (Tps) 2.4.1.15 Helicoverpa armigera AAY87162.2
ACH88521.1
B5TD29  
 α,α-trehalose-phosphate synthase (Tps1;Ggs1) 2.4.1.15 Kluyveromyces lactis ATCC 8585 AAN95307.1
CAA51164.1
CBF70308.1
CBG04453.1
Q07158  
 trehalose-6-phosphate synthase subunit 1 (TPS1) 2.4.1.15 Magnaporthe grisea GUY11 AAN46744.1
CBF70394.1
CBF98911.1
Q875L7  
 trehalose-6-P synthase 1 (Tps1) 2.4.1.15 Metarhizium acridum CQMA102 AAX55633.1 Q58FS5  
 trehalose-6-P synthase (Tps1;SNOG_09603;SNU09603.1) (17486) 2.4.1.15 Phaeosphaeria nodorum SN15 EAT82868.2    
 α,α-trehalose-phosphate synthase (Tps1) 2.4.1.15 Pichia angusta AAX06612.1
CAB38058.1
CBF70454.1
CBF98940.1
O94213.1  
 trehalose phosphate synthase (Tps3) 2.4.1.15 Pichia angusta CBS4731 AAF73139.1 Q9P918  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15 Saccharomyces cerevisiae AS2.1416 AAC16974.1 Q00764  
 trehalose-6-phosphate synthase (Tps1;Cif1) 2.4.1.15 Saccharomyces cerevisiae C836 AAE24073.1
AAO30562.1
CAA43580.1
Q00764  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15 Saccharomyces cerevisiae FHS AAT27374.1 Q00764  
 α,α-trehalose-phosphate synthase (Tsl1;YML100w) 2.4.1.15 Saccharomyces cerevisiae S288c AAO30641.1
CAA51303.1
CAA56797.1
CBF70306.1
CBG04452.1
NP_013608.1
P38427  
 α,α-trehalose-6-phosphate synthase (Tps1;Cif1;Byp1;Fdp1;Ggs1;Glc6;YBR126c;YBR0922) 2.4.1.15 Saccharomyces cerevisiae S288c AAA53672.1
AAN95308.1
AAT93166.1
ABL11219.1
AEP68447.1
AEP68448.1
AEP68449.1
AEP68450.1
AEP68451.1
AEP68452.1
AEP68453.1
AEP68454.1
AEP68455.1
AEP68457.1
AEP68458.1
AEP68459.1
AEP68460.1
AEP68461.1
AEP68462.1
AEP68464.1
AEP68469.1
AEP68471.1
AEP68472.1
AEP68473.1
AEP68474.1
AEP68475.1
AEP68476.1
AEP68477.1
AEP68478.1
AEP68479.1
AEP68480.1
AEP68481.1
AEP68482.1
AEP68483.1
AEP68484.1
AEP68485.1
AEP68486.1
AEP68487.1
AEP68488.1
AEP68489.1
AEP68490.1
AEP68491.1
AEP68492.1
AEP68493.1
AEP68494.1
AEP68495.1
AEP68496.1
AEP68497.1
AEP68498.1
AEP68499.1
AEP68500.1
AEP68501.1
AEP68503.1
AEP68504.1
AEP68505.1
AEP68506.1
AEP68507.1
AEP68508.1
AEP68510.1
AEP68511.1
AEP68512.1
AEP68513.1
AEP68514.1
AEP68515.1
AEP68516.1
AEP68517.1
AEP68518.1
AEP68519.1
CAA47834.1
CAA48510.1
CAA53485.1
CAA85083.1
CBF70304.1
CBG04451.1
NP_009684.1
Q00764.2  
 α,α-trehalose-phosphate synthase (Tps2;Pfk3;YDR074w;YD8554.07) 2.4.1.15 Saccharomyces cerevisiae S288c AAV19882.1
CAA50025.1
CAA86796.1
CAA98893.1
CBF70310.1
CBG04454.1
NP_010359.1
P31688.3  
 α,α-trehalose-phosphate synthase (Tps3;YMR261c;YM8156.03C) 2.4.1.15 Saccharomyces cerevisiae S288c AAA35224.1
AAT92987.1
CAA89244.1
NP_013988.1
P38426  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15 Saccharomyces cerevisiae WFB AAT27376.1 Q00764  
 trehalose-6-P synthase (Tps1) 2.4.1.15 Saccharomycopsis fibuligera A11 ABD47524.1
ABD47524.2
ADQ43750.1
Q27V66  
 α,α-trehalose-phosphate synthase (Tps1;SPAC328.03) 2.4.1.15 Schizosaccharomyces pombe 972h- AAN95310.1
CAA82861.1
CAB95998.1
CBF70327.1
CBF70456.1
CBF98941.1
CBG04462.1
NP_594205.1
P40387.2  
 α,α-trehalose-phosphate synthase 2.4.1.15 Selaginella lepidophylla AAD00829.1
CAB69548.1
CAB69549.1
CBF70333.1
CBG04465.1
Q9ZR75  
 trehalose-6-phosphate synthase (Tps1) 2.4.1.15 Zygosaccharomyces rouxii KACC30010 AAK69413.1
CBF70460.1
CBF98943.1
Q96WK6  
 trehalose-6-phosphate phosphatase (Tps2) 3.1.3.12 Zygosaccharomyces rouxii KACC30010 AAF80562.1
CBF70440.1
CBF98933.1
Q9P4D3  

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.





Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II