GlycosylTransferase Family 1

Activities in FamilyUDP-glucuronosyltransferase (EC 2.4.1.17); zeatin O-β-xylosyltransferase (EC 2.4.2.40); 2-hydroxyacylsphingosine 1-β-galactosyltransferase (EC 2.4.1.45); N-acylsphingosine galactosyltransferase (EC 2.4.1.47); flavonol 3-O-glucosyltransferase (EC 2.4.1.91); anthocyanidin 3-O-glucosyltransferase (EC 2.4.1.115); sinapate 1-glucosyltransferase (EC 2.4.1.120); indole-3-acetate β-glucosyltransferase (EC 2.4.1.121); flavonol L-rhamnosyltransferase (EC 2.4.1.159); sterol glucosyltransferase (EC 2.4.1.173); UDP-Glc: 4-hydroxybenzoate 4-O-β-glucosyltransferase (EC 2.4.1.194); zeatin O-β-glucosyltransferase (EC 2.4.1.203); limonoid glucosyltransferase (EC 2.4.1.210); UDP-GlcA: baicalein 7-O-β-glucuronosyltransferase (EC 2.4.1.253); UDP-Glc: chalcone 4′-O-β-glucosyltransferase (EC 2.4.1.286); ecdysteroid UDP-glucosyltransferase (EC 2.4.1.-); salicylic acid β-glucosyltransferase (EC 2.4.1.-); anthocyanin 3-O-galactosyltransferase (EC 2.4.1.-); anthocyanin 5-O-glucosyltransferase (EC 2.4.1.-); dTDP-β-2-deoxy-L-fucose: α-L-2-deoxyfucosyltransferase (EC 2.4.1.-); UDP-β-L-rhamnose: α-L-rhamnosyltransferase (EC 2.4.1.-); zeaxanthin glucosyltransferase (EC 2.4.1.-)
Mechanism Inverting
3D Structure StatusGT-B
NoteDistantly related to family GT28; several members of this family are made of two subunits (for instance Alg13 and Alg14 in Saccharomyces); the complete enzyme has been reconstituted whenever possible, and appears with the two subunit names separated by a + sign and with the N-terminal subunit followed by the C-terminal one
External resourcesArabidopsis GT1s; CFG(Glycosphingolipid); Glymap;
Commercial Enzyme Provider(s)PROZOMIX;
Statistics GenBank accession (18406); Uniprot accession (3361); PDB accession (68); 3D entries (31); cryst (2)
All (13599) Archaea (189) Bacteria (8500) Eukaryota (4672) Viruses (213) unclassified (25) Structure (31 - 2 cryst) Characterized (371)
| 1 | 2 | 3 | 4 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 indolocarbazole N-glucosyltransferase (AtmG;AtG) 2.4.1.- Actinomadura melliaura SCC 1655 ABC02800.1 Q0H2W4  
 UDP-GlcNAc: teicoplanin aglycone 4Hpg-N-acetylglucosaminidase (Tcp23;Orf10*;GtfB) 2.4.1.- Actinoplanes teichomyceticus ATCC31131 CAE53364.1
CAG15022.1
Q6ZZI3  
 UDP-GlcNAc: teicoplanin aglycone 3-Cl-6-β-Hty-N-acetylglucosaminidase (Tcp8;Orf1;GtfA) 2.4.1.- Actinoplanes teichomyceticus ATCC31131 CAE53349.1
CAG15008.1
Q6ZZJ7  
 ansamitocin N-β-glucosyltransferase (Asm25) 2.4.1.- Actinosynnema pretiosum subsp. auranticum ATCC 31565 AAM54103.1 Q8KUH5  
 UDP-Glc: balhimycin aglycone Hpg-glucosyltransferase B (BgtfB) 2.4.1.- Amycolatopsis balhimycina DSM 5908 CAA76552.1 O87678  
 dTDP-β-L-4-epi-epivancosamine: epivancosaminyltransferase (GtfA;PCZA361.19) 2.4.1.- Amycolatopsis orientalis A82846 AAB49292.1
AAE12045.1
CAA11774.1
P96558 1PN3[A,B]
1PNV[A,B]
 TDP/UDP-Glc: aglycosyl-vancomycin: glucosyltransferase (GtfB;PCZA361.20) 2.4.1.- Amycolatopsis orientalis A82846 AAB49293.1
AAE12046.1
CAA11775.1
P96559 1IIR[A]
 UDP-β-L-4-epi-vancosamine: vancomycin-pseudoaglycone vancosaminyltransferase (GtfC;PCZA361.21) 2.4.1.- Amycolatopsis orientalis A82846 AAB49294.1
AAE12043.1
CAA11776.1
P96560  
 TDB/UDP-Glc: aglycosyl-vancomycin glucosyltransferase (GtfE) 2.4.1.- Amycolatopsis orientalis ATCC19795 AAK31353.1
CCD33144.1
Q9AFC6  
 UDP-β-L-4-epi-vancosamine: vancomycin-pseudoaglycone vancosaminyltransferase (GtfD) 2.4.1.- Amycolatopsis orientalis ATCC19795 AAK31352.1
CCD33143.1
Q9AFC7 1RRV[A,B]
 UDP-β-L-4-epi-vancosamine: vancomycin-pseudoaglycone vancosaminyltransferase (GtfD';Vcm9) 2.4.1.- Amycolatopsis orientalis C329.4 / HCCB10007 AAB49298.1
AAE12044.1
AEI58872.1
P96564  
 TDP/UDP-Glc: aglycosyl-vancomycin glucosyltransferase (GtfE';Vcm10) 2.4.1.- Amycolatopsis orientalis C329.4 / HCCB10007 AAB49299.1
AAE71060.1
AAQ31820.1
ACK12107.1
AEI58873.1
P96565  
 flavonoid β-3(7)-O-glucosyltransferase (BcGT-3;BCE2825) 2.4.1.- Bacillus cereus ATCC 10987 AAS41737.1
NP_979129.1
Q736S5  
 UDP-Glc: β-glucosyltransferase (BcGT-1;BCE2168) 2.4.1.- Bacillus cereus ATCC 10987 AAS41089.1
NP_978481.1
Q739H3  
 UDP-Glc: isoflavonoid β-glucosyltransferase (YjiC;BLi01948;BL00446) 2.4.1.- Bacillus licheniformis DSM 13 = ATCC 14580 AAU40842.1
AAU23479.1
Q65JC2  
 monogalactosyldiacylglycerol synthase (UDP-Gal dependent) (MgdA;CT0344) 2.4.1.46 Chlorobium tepidum TLS AAM71590.1    
 tiacumicin 2-O-methyl-d-rhamnosyltransferase (TiaG2) 2.4.1.- Dactylosporangium aurantiacum subsp. hamdenensis NRRL 18085 ADU85989.1    
 tiacumicin 5-C-methyl-d-rhamnosyltransferase (TiaG1) 2.4.1.- Dactylosporangium aurantiacum subsp. hamdenensis NRRL 18085 ADU86026.1    
 UDP-Glc: Ent C-glucosyltransferase (IroB;c1254) 2.4.-.- Escherichia coli CFT073 AAN79728.1
NP_753168.1
   
 rebeccamycin N-glucosyltransferase (RebG;RbmA) 2.4.1.- Lechevalieria aerocolonigenes ATCC 39243 CAC93713.1
AAN01207.1
BAC10673.1
BAC15749.1
Q8KHE4  
 indolocarbazole N-glucosyltransferase (NGT) 2.4.1.- Lechevalieria aerocolonigenes ATCC 39243 BAA83130.1 Q8KHE4
Q9S595
 
 dTDP-D-desosamine: 3-α-mycarosylerythronolide B desosaminyltransferase (MegCIII) 2.4.1.- Micromonospora megalomicea CAC37820.1
AAG13921.1
   
 mycarosyltransferase (MegBV) 2.4.1.- Micromonospora megalomicea CAC37814.1
AAG13915.1
   
 rhodosaminyltransferase (MegDI) 2.4.1.- Micromonospora megalomicea CAC37807.1
AAG13908.1
   
 SaqAE62 α-1,4-L-2-deoxyfucosyltransferase (SaqGT6) 2.4.1.- Micromonospora sp. Tu 6368 ACP19375.1 C4NYM1  
 SaqAE1 (L-rhodinose) α-1,4-L-rhodinosyltransferase (SaqGT1) 2.4.1.- Micromonospora sp. Tu 6368 ABO27084.1
ACP19361.1
A4GV04
C4NYK7
 
 aquayamycin α-L-rhodinosyltransferase (SaqGT2) 2.4.1.- Micromonospora sp. Tu 6368 ABO27085.1
ACP19363.1
A4GV05
C4NYK9
 
 SaqAE3 (L-rhodinose) β-1,4A-olivosyltransferase (SaqGT3) 2.4.1.- Micromonospora sp. Tu 6368 ABO27086.1
ACP19364.1
A4GV06
C4NYL0
 
 rhamnosyltransferase A (RtfA) 2.4.1.- Mycobacterium avium 2151 AAD44209.1
AAR24891.1
O69000  
 GPL/6-deoxytalose α-L-1,2-rhamnosyltransferase A (GtfA) 2.4.1.- Mycobacterium avium TMC 724 AAC71701.1
AAD20363.1
AAD44208.1
O68999  
 GPL/6-deoxytalose α-L-1,2-rhamnosyltransferase A (RtfA;Orf2) 2.4.1.- Mycobacterium avium TMC 724 AAC71702.1
AAD20364.1
AAR24884.1
O69000  
 GPL/3,4-di-O-Me-rhamnose α-L-1,2-(3-O-methyl-)rhamnosyltransferase (Gtf3;MSMEG_0385) 2.4.1.- Mycobacterium smegmatis str. MC2 155 AAN28688.1
ABB72065.1
ABK71089.1
AFP36859.1
AIU05662.1
Q2YHI4
Q8GJ80
 
 MT3034 2.4.1.- Mycobacterium tuberculosis CDC1551 AAK47360.1
NP_337546.1
P9WFR0  
 mono-rhamnosylated phenophthiocerol dimycocerosate glycosyltransferase (Rv2958c) 2.4.1.- Mycobacterium tuberculosis H37Rv CAB05418.1
AAA50940.1
AFN50940.1
CCP45762.1
NP_217474.1
P95134
Q50458
 
 p-hydroxybenzoic acid ethyl ester rhamnosyltransferase (Rv2962c) 2.4.1.- Mycobacterium tuberculosis H37Rv CAB05415.1
AAA50942.1
AAA50943.1
AFN50944.1
CCP45766.1
NP_217478.1
P95130
Q50455
Q50456
 
 UDP-Glc: zeaxanthin glucosyltransferase (CrtX;Ugt101) 2.4.1.- Pantoea agglomerans Eho10 AAA64979.1 Q01330  
 zeaxanthin glucosyltransferase (CrtX) 2.4.1.- Pantoea ananatis BAA14125.1 P21686  
 rhamnosyltransferase (RhlB;PA3478) 2.4.1.- Pseudomonas aeruginosa PAO1 AAG06866.1
NP_252168.1
Q9HYD1  
 TDP-desosamine: α-mycarosyl erythronolide B desosaminyltransferase (EryCIII;SACE_0726) 2.4.1.- Saccharopolyspora erythraea NRRL 2338 CAA74710.1
AAB84067.1
AAE39406.1
CAM00067.1
A4F7P3
O54224
2YJN[A,B]
 TDP-β-L-Rha: spinosyn 9-O-α-L-rhamnosyltransferase (SpnG) 2.4.1.- Saccharopolyspora spinosa NRLL18537 AAG23268.1
AAP01018.1
ABE23716.1
ABX94159.1
Q9ALM8 3TSA[A,B]
3UYK[A,B]
3UYL[A,B]
 UDP-Glc: sorangicin A glucosyltransferase (SorF) 2.4.1.- Sorangium cellulosum So ce12 ADN68481.1 E5FNE9  
 UDP-GlcA: (gellan) α-Glc-PP-C55 β-1,4-glucuronosyltransferase (GelK) 2.4.1.- Sphingomonas elodea ATCC 31461 AAP57686.1 Q7X2M3  
 β-1,4-glucuronosyltransferase (GelK) 2.4.1.- Sphingomonas elodea ATCC31461 AAG59805.1 Q7X2M3  
 β-1,4-glucuronosyltransferase (SpsK) 2.4.1.- Sphingomonas sp. S88 AAC44060.1 P74819  
 UDP-Glc: oleandomycin β-glucosyltransferase (OleI) 2.4.1.- Streptomyces antibioticus ATCC 11891 AAC12648.1 O68841  
 UDP-Glc: oleandomycin glycosyltransferase (OleD;UGT102A2) 2.4.1.- Streptomyces antibioticus ATCC 11891 DSM 40868 ABA42119.2
CAA80301.1
Q3HTL6
Q53685
2IYF[A,B]
4M60[A]
4M7P[A]
4M83[A,B]
 oleandomycin glycosyltransferase (OleI) 2.4.1.- Streptomyces antibioticus DSM 40868 ATCC 11891 ABA42118.2
ABA42118.1
Q3HTL7 2IYA[A,B]
 premithramycin A1 D-olivosyltransferase (MtmGIII) 2.4.1.- Streptomyces argillaceus ATCC12956 AAD55583.1
CAK50789.1
Q194P9
Q9RQR5
 
 premithramycinone D-olivosyltransferase (MtmGIV) 2.4.1.- Streptomyces argillaceus ATCC12956 AAD55582.1
CAK50788.1
Q194Q0
Q9RQR6
 
 3A-Deolivosylpremithramycin B D-olivosyltransferase (premithramycin B synthase) (MtmGII) 2.4.1.- Streptomyces argillaceus ATCC12956 AAC64927.1
CAK50792.1
O87479
Q194P6
 
 D-olivosyltransferase (MtmGI) 2.4.1.- Streptomyces argillaceus ATCC12956 AAC64928.1
CAK50793.1
O87480
Q194P5
 
 TDP-L-oleandrose: avermectin iterative α-L-oleandrosyltransferase (AveBI) 2.4.1.- Streptomyces avermitilis BAA84592.1 Q9S0P6  
 TDP-L-noviose: novobiocic acid α-L-noviosyltransferase (NovM) 2.4.99.- Streptomyces caeruleus NCIB 11891 AAF67506.1 Q9L9F5  
 GDP-mycosamine: natamycinolide [macrolide] β-mycosaminyltransferase (ScnK) 2.4.1.- Streptomyces chattanoogensis L10 ADD85130.2
ADD85130.1
D4P8Q9  
 SCO6090 or SCBAC1A6.14 2.4.1.- Streptomyces coelicolor A3(2) CAC33935.1
NP_630198.1
Q9ADH3  
 8-O-tetrangulol β-D-olivosyltransferase (LanGT2) 2.4.1.- Streptomyces cyanogenus S136 AAD13553.1 Q9ZGC0 4RIE[A,B]
4RIF[A,B]
4RIG[A,B]
4RIH[A,B]
4RII[A,B]
 olivosyltransferase (LanGT1) 2.4.1.- Streptomyces cyanogenus S136 AAD13555.1 Q9ZGB8  
 olivosyltransferase (LanGT3) 2.4.1.- Streptomyces cyanogenus S136 AAD13559.1 Q9ZGB4  
 L-rhodinosyltransferase (LanGT4) 2.4.1.- Streptomyces cyanogenus S136 AAD13562.1 Q9ZGB1  
 TDP-L-Rha: CBS000020 α-L-rhamnosyltransferase (aranciamycin synthase) (AraGT;Orf21) 2.4.1.- Streptomyces echinatus SSP. AFGHANENSIS TU303 DSM 40730 ABL09968.1 A1C188  
 mycarosyltransferase (TylCV) 2.4.1.- Streptomyces fradiae AAD41824.1 Q9XC67  
 TDP-D-mycaminose : tylactone mycaminyltransferase (TylMII;Orf2*) 2.4.1.- Streptomyces fradiae CAA57472.2 P95747  
 deoxyallosyl-transferase (TylN) 2.4.1.- Streptomyces fradiae AAD12163.1
CAA06512.2
CAB37346.2
O70023  
 C-12β-L-rhodinosyltransferase (UrdGT1a) 2.4.1.- Streptomyces fradiae T#2717 AAF00214.1 Q9RPA2  
 (12b -derhodinosyl-)urdamycin G D-olivosyltransferase (UrdGT1b) 2.4.1.- Streptomyces fradiae T#2717 AAF00215.1 Q9RPA1  
 aquayamycin / urdamycinone B L-rhodinosyltransferase (UrdGT1c) 2.4.1.- Streptomyces fradiae T#2717 AAF00217.1 Q9RP99  
 D-olivosyltransferase (UrdGT2) 2.4.1.- Streptomyces fradiae T#2717 AAF00209.1 Q9RPA7 2P6P[A,B]
 dTDP-β-2-deoxy-L-fucose α-L-2-deoxyfucosyltransferase (AclK) 2.4.-.- Streptomyces galilaeus 3AR-33 BAB72041.1 Q8VWB7  
 dTDP-L-rhodosamine:aklavinone α-L-rhodosaminyltransferase (AknS) 2.4.1.- Streptomyces galilaeus ATCC 31615 AAF73455.1 Q9L4U6  
 dTDP-β-2-deoxy-L-fucose α-L-2-deoxyfucosyltransferase (AknK) 2.4.-.- Streptomyces galilaeus ATCC31615 AAF70102.1 Q9L555  
 β-olivosyltransferase (LndGT1) 2.4.1.- Streptomyces globisporus 1912 AAS20331.1 Q6QR18  
 gilvocarcin E C-glycosyltransferase (GilGT) 2.-.-.- Streptomyces griseoflavus GOE 3592 AAP69578.2 Q7X2H0  
 D-olivosyltransferase (CmmGIV) 2.4.1.- Streptomyces griseus subsp. griseus ATCC 13273 CAE17547.1 Q70J68  
 premithramycin A1 / deacteyl-prechromomycin A3 D-olivosyltransferase (CmmGII) 2.4.1.- Streptomyces griseus subsp. griseus ATCC 13273 CAE17548.1 Q70J67  
 D-olivosyltransferase (CmmGIII) 2.4.1.- Streptomyces griseus subsp. griseus ATCC 13273 CAE17545.1 Q70J70  
 dideacetyl-prechromomycin A4 D-olivosyltransferase (CmmGI) 2.4.1.- Streptomyces griseus subsp. griseus ATCC 13273 CAE17535.1 Q70J80  
 dTDP-vicenisamine: vicenilactam β-vicenisaminyltransferase (VinC) 2.4.1.- Streptomyces halstedii HC34 BAD08357.1 Q76KZ6 3WAD[A,B]
3WAG[A,B]
 macrolide glycosyltransferase (MGT) 2.4.1.- Streptomyces lividans DSMZ 46482 ABA28305.1
ABA28305.2
Q3LRZ5  
 macrolide glycosyltransferase (Mgt;UGT102A1) 2.4.1.- Streptomyces lividans TK21 AAA26780.1 Q54387  
 N-glycosyltransferase (StaG) 2.-.-.- Streptomyces longisporoflavus DSM 10189 CAD58668.1 Q5QT13  
 TDP-nogalamine : 3prime,4prime-demethoxynogalose-1-hydroxynogalamycinone nogalaminyltransferase (SnogD) 2.4.1.- Streptomyces nogalater AAF01811.1 Q9RN61 4AMB[A,B]
4AMG[A,B]
4AN4[A,B,C,D]
 GDP-mycosamine: nystatin [macrolide] β-mycosaminyltransferase (NysDI) 2.4.1.- Streptomyces noursei ATCC 11455 AAF71773.1
ANZ14075.1
Q9L4W6  
 glycosyltransferase (CosK) 2.4.1.- Streptomyces olindensis DAUFPE 5622 ABC00725.1 Q2PZS3  
 cosmomycin α-L-rhodosaminyltransferase (CosG) 2.4.1.- Streptomyces olindensis DAUFPE 5622 ABC00729.1 Q2PZR4  
 dTDP-L-Rha: 8-demethyl-tetracenomycin C α-L-rhamnosyltransferase / elloramycin glycosyltransferase (ElmGT) 2.4.1.- Streptomyces olivaceus CAC16413.2
CAC32467.1
CAP12607.1
Q9F2F9  
 lactonamycinone glycosyltransferase (Lct36) 2.4.1.- Streptomyces rishiriensis MJ773-88K4 ABX71119.1 B0LJ19  
 lactonamycin glycosyltransferase (Lcz36) 2.4.1.- Streptomyces sanglieri AK 623 ABX71153.1 B0LJ53  
 C-glycosyl transferase (Med-ORF8) 2.-.-.- Streptomyces sp. AM-7161 BAC79040.1 Q7WT14  
 β-mycosaminyltransferase (FscMI) 2.4.1.- Streptomyces sp. FR-008 AAQ82555.1
ALM43425.1
Q6W5Q9  
 TDP-D-chalcose: macrolide chalcosyltransferase / TDP-D-desosamine: macrolide D-desosaminyltransferase (GerTII) 2.4.1.- Streptomyces sp. KCTC 0041BP ABB52547.1 Q331Q0  
 N-glycosyltransferase (StaG) 2.-.-.- Streptomyces sp. TP-A0274 BAC55209.1 Q83WG5  
 steffimycin L-rhamnosyltransferase (StfG) 2.4.1.- Streptomyces steffisburgensis ISP 5547 CAJ42338.1 Q2P9Y9  
 TDP-D-desosamine: 10-deoxymethynolide/narbonolide desosaminyltransferase (DesVII) 2.4.1.- Streptomyces venezuelae AAC68677.1
AAO96652.1
AAO98871.1
AAY77313.1
Q9ZGH7  
 2,6-dideoxy-α-L-ribohexopyranosyltransferase (JadS) 2.4.99.- Streptomyces venezuelae ISP5230 AAL14252.1 Q939Q6  
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 UDP-Glc: flavonoid glucosyltransferase (UGT73G1) 2.4.1.- Allium cepa AAP88406.1
CAX02471.1
CBD06629.1
Q7XJ50  
 UDP-Glc: flavonoid glucosyltransferases (UGT73J1) 2.4.1.- Allium cepa AAP88407.1
CAX02470.1
CBD06627.1
Q7XJ49  
 UDP-Glc: chalcone 4'-O-β-glucosyltransferase (Am4'CGT) 2.4.1.286 Antirrhinum majus BAE48239.1
ABR57234.1
AFC90118.1
CAX02388.1
CBD06466.1
Q33DV3  
 UDP-GlcA: scutellarein 7-O-β-glucuronosyltransferase (AmUGTcg10;UGT88D4) (UGT88D4) 2.4.1.- Antirrhinum majus BAG31945.1 B2NIC9  
 UDP-Glc: indole-3-carboxylic acid-, coniferyl alcohol-, flavonoid 7-O-glucosyltransferase (UGT73B2;AtGT-1;At4g34135) 2.4.1.237 Arabidopsis thaliana AAK59668.1
AAM65945.1
AAN13230.1
AAR01231.1
AEE86328.1
AEE86329.1
AHL38663.1
NP_567954.1
NP_849492.1
Q8L9I7
Q94C57
 
 UDP-Glc: flavonoid O7-glucosyltransferase; (GT-2;AtUGT73B1;At4g34138) 2.4.1.- Arabidopsis thaliana AAL57652.1
AAL90934.1
AAN31894.1
AEE86330.1
AHL38662.1
BAD94752.1
NP_567955.1
Q8VZE9  
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