Activities in Family | UDP-GalNAc: β-1,4-N-acetylgalactosaminyltransferase (EC 2.4.1.-); |
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Mechanism | inverting (inferred) |
3D Structure Status | GT-A |
Note | Family created after Hirata et al., 2018 (PMID=29374258) who have shown that the human enzyme probably is a b-1,4-N-acetylgalactosaminyltransferase that adds GalNAc to the first mannose residue of GPI anchors; the GTs of this family are characterized by the presence of two transmembrane domains inserted in the GT-A fold; very distant relatedness to GT54 |
Statistics | GenBank accession (77); Uniprot accession (1); |
Eukaryota | |||||||
Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | ||
R9X50_00757400 | Acrodontium crateriforme isolate 169a | WPH04681.1 | |||||
I4U23_026362 | Adineta vaga | UJR23350.1 | |||||
I4U23_006896 | Adineta vaga | UJR25551.1 | |||||
L3Y34_017315 | Caenorhabditis briggsae isolate QX1410_ONT | ULU04458.1 | |||||
CELE_F35C11.4 | Caenorhabditis elegans Bristol N2 | CAA90244.1 | |||||
transmembrane protein, partial (fragment) | Callorhinchus milii | AFP08214.1 | |||||
568363 | Fimicolochytrium jonesii JEL569 v1.0 (Fimjon1) | ||||||
306280 | Geranomyces variabilis JEL559 v1.0 (Gervar1) | ||||||
148472 | Guillardia theta CCMP2712 (Guith1) | ||||||
UDP-Gal: [GPI-anchor] β-1,4-N-acetylgalactosaminyltransferase (TMEM246; C9orf125) | 2.4.1.- | Homo sapiens | AAH06115.1 AAH33550.1 SJX37796.1 |
Q9BRR3 | |||
transmembrane protein C9orf125 | Macaca mulatta | AFE64597.1 | |||||
1938 | Metarhizium anisopliae ARSEF 549 (Metani1) | ||||||
unnamed protein product | Mus musculus C57BL/6J | BAE38239.1 BAC30023.1 BAC30454.1 BAC31328.1 BAC32406.1 BAC36105.1 |
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unnamed protein product | Mus musculus C57BL/6J | BAB28725.1 | |||||
MAR_000283 | Mya arenaria isolate MELC-2E11 | WAR18445.1 | |||||
KARACHINF001_ LOCUS 3270 | Naegleria fowleri | CAG4710915.1 | |||||
66228 | Naegleria gruberi (Naegr1) | ||||||
OCTVUL_1B009500 | Octopus vulgaris | CAI9718775.1 | |||||
PECUL_23A052044 | Pelobates cultripes | CAH2321457.1 | |||||
MPIPNATIZW_LOCUS2069 | Pipistrellus nathusii | CAK6433763.1 | |||||
PODLI_1B022037 | Podarcis lilfordi | CAI5796646.1 | |||||
124988 | Powellomyces hirtus BR81 v1.0 (Powhir1) | ||||||
ORF | Pristionchus pacificus PS312 | ACZ54500.1 ADA57112.1 ADA57113.1 ADA57114.1 ADA57115.1 ADA57116.1 |
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MRATA1EN1_LOCUS20237 | Rangifer tarandus platyrhyncus | CAI9171275.1 | |||||
2657 | Rozella allomycis CSF55 (Rozal1_1) | ||||||
SMAX5B_005525 | Scophthalmus maximus | AWP05192.1 | |||||
chromosome 9 open reading frame 125 (fragment) | Xenopus clivii | AEP24458.1 AEP24455.1 AEP24456.1 AEP24457.1 AEP24459.1 AEP24460.1 AEP24461.1 AEP24462.1 AEP24463.1 AEP24464.1 AEP24465.1 AEP24466.1 AEP24467.1 AEP24468.1 AEP24469.1 AEP24470.1 AEP24471.1 AEP24472.1 AEP24473.1 AEP24474.1 AEP24475.1 AEP24476.1 AEP24477.1 AEP24478.1 AEP24479.1 AEP24480.1 |
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LOC100137688 protein (fragment) | Xenopus laevis | AAI57723.1 | |||||
chromosome 9 open reading frame 125, partial | Xenopus largeni | AEP24496.1 AEP24481.1 AEP24482.1 AEP24483.1 AEP24484.1 AEP24485.1 AEP24486.1 AEP24487.1 AEP24488.1 AEP24489.1 AEP24490.1 AEP24491.1 AEP24492.1 AEP24493.1 AEP24494.1 AEP24495.1 AEP24497.1 AEP24498.1 |
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XNOV1_A029855 | Xyrichtys novacula | CAJ1054146.1 | |||||
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