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GlycosylTransferase Family 108

Activities in FamilyGDP-α-D-Manp: β-1,2-D-mannosyltransferase (EC 2.4.1.374);
Mechanism inverting
NoteCreated after (Sernee et al., Cell Host & Microbe, 2019), in press [PMID=31513773]. The dual activity mannosyltransferases/phosphorylases of six Leishmania proteins allows the management of mannogen (storage polysacharride). Family evolutionary related the bacterial GH130 phosphorylases.
Statistics GenBank accession (642); Uniprot accession (6); PDB accession (6); 3D entries (4); cryst (0)
Summary
Download GT108 (627) Taxonomic display Structure (4) Characterized (6)
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Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ADEAN_001012100 (fragment)   Angomonas deanei Crithidia deanei Carvalho (ATCC PRA-265) CAD2222577.1    
 ADEAN_001012200 (fragment)   Angomonas deanei Crithidia deanei Carvalho (ATCC PRA-265) CAD2222578.1    
 ADEAN_001011800   Angomonas deanei Crithidia deanei Carvalho (ATCC PRA-265) CAD2222574.1    
 ADEAN_001012300   Angomonas deanei Crithidia deanei Carvalho (ATCC PRA-265) CAD2222579.1    
 ADEAN_001011900   Angomonas deanei Crithidia deanei Carvalho (ATCC PRA-265) CAD2222575.1    
 ADEAN_001012000   Angomonas deanei Crithidia deanei Carvalho (ATCC PRA-265) CAD2222576.1    
 ADEAN_001012400   Angomonas deanei Crithidia deanei Carvalho (ATCC PRA-265) CAD2222580.1    
 ORF   Leishmania amazonensis HSJD-1 AKK31186.1    
 ORF   Leishmania braziliensis complex EV-2015 L2237/05 AKK31187.1    
 ORF   Leishmania braziliensis L2346/05 AKK31188.1    
 LBRM2904WSI_LOCUS3053   Leishmania braziliensis M2309 CAJ2467960.1    
 LBRM2904WSI_LOCUS3059   Leishmania braziliensis M2309 CAJ2467966.1    
 LBRM2904WSI_LOCUS3051   Leishmania braziliensis M2309 CAJ2467958.1    
 LBRM2904WSI_LOCUS3057   Leishmania braziliensis M2309 CAJ2467964.1    
 LBRM2904WSI_LOCUS3049   Leishmania braziliensis M2309 CAJ2467956.1    
 LBRM2904WSI_LOCUS3055   Leishmania braziliensis M2309 CAJ2467962.1    
 LBRM2904WSI_LOCUS3047   Leishmania braziliensis M2309 CAJ2467954.1    
 LBRM2903WSI_LOCUS3387   Leishmania braziliensis M2309 CAJ2468550.1    
 LBRM2903WSI_LOCUS3381   Leishmania braziliensis M2309 CAJ2468547.1    
 LBRM2903WSI_LOCUS3377   Leishmania braziliensis M2309 CAJ2468545.1    
 LBRM2903WSI_LOCUS3379   Leishmania braziliensis M2309 CAJ2468546.1    
 LBRM2903WSI_LOCUS3389   Leishmania braziliensis M2309 CAJ2468551.1    
 LBRM2903WSI_LOCUS3383   Leishmania braziliensis M2309 CAJ2468548.1    
 LBRM2903WSI_LOCUS3385   Leishmania braziliensis M2309 CAJ2468549.1    
 LBRM_10_1400   Leishmania braziliensis MHOM/BR/75/M2904 CAM37341.1    
 LBRM_10_1420   Leishmania braziliensis MHOM/BR/75/M2904 CAM37343.1    
 LBRM2904_10.1760   Leishmania braziliensis MHOM/BR/75/M2904 SYZ63546.1    
 LBRM2904_10.1810   Leishmania braziliensis MHOM/BR/75/M2904 SYZ63551.1    
 LBRM_10_1380   Leishmania braziliensis MHOM/BR/75/M2904 CAM37339.1    
 LBRM2904_10.1780   Leishmania braziliensis MHOM/BR/75/M2904 SYZ63548.1    
 LBRM_10_1430   Leishmania braziliensis MHOM/BR/75/M2904 CAM37344.1    
 LBRM_10_1390   Leishmania braziliensis MHOM/BR/75/M2904 CAM37340.1    
 LBRM2904_10.1750   Leishmania braziliensis MHOM/BR/75/M2904 SYZ63545.1    
 LBRM2904_10.1770   Leishmania braziliensis MHOM/BR/75/M2904 SYZ63547.1    
 LBRM2904_10.1790   Leishmania braziliensis MHOM/BR/75/M2904 SYZ63549.1    
 LBRM2904_10.1800   Leishmania braziliensis MHOM/BR/75/M2904 SYZ63550.1    
 LBRM_10_1440   Leishmania braziliensis MHOM/BR/75/M2904 CAM37345.1    
 LBRM_10_1410   Leishmania braziliensis MHOM/BR/75/M2904 CAM37342.1    
 LDBPK_101410   Leishmania donovani CBZ32258.1    
 LDHU3_10.1820   Leishmania donovani CAC5428099.1    
 LDHU3_10.1810   Leishmania donovani CAC5428098.1    
 LDHU3_10.1740   Leishmania donovani CAC5428093.1    
 LDHU3_10.1770   Leishmania donovani CAC5428095.1    
 LDHU3_10.1790   Leishmania donovani CAC5428096.1    
 LDHU3_10.1760   Leishmania donovani CAC5428094.1    
 LDHU3_10.1800   Leishmania donovani CAC5428097.1    
 LDHU3_10.1770:CDS1 (Ldhu3_10.1770T)   Leishmania donovani CAJ1986818.1    
 LDHU3_10.1800:CDS1 (Ldhu3_10.1800T)   Leishmania donovani CAJ1986820.1    
 LDHU3_10.1760:CDS1 (Ldhu3_10.1760T)   Leishmania donovani CAJ1986817.1    
 LDHU3_10.1820:CDS1 (Ldhu3_10.1820T)   Leishmania donovani CAJ1986822.1    
 LDHU3_10.1810:CDS1 (Ldhu3_10.1810T)   Leishmania donovani CAJ1986821.1    
 LDHU3_10.1740:CDS1 (Ldhu3_10.1740T)   Leishmania donovani CAJ1986816.1    
 LDBPK_101390   Leishmania donovani BPK282A1 CBZ32256.1    
 LDBPK_101370   Leishmania donovani BPK282A1 CBZ32254.1    
 LDBPK_101380   Leishmania donovani BPK282A1 CBZ32255.1    
 LDBPK_101430   Leishmania donovani BPK282A1 CBZ32260.1    
 LDBPK_101420   Leishmania donovani BPK282A1 CBZ32259.1    
 LDBPK_101400   Leishmania donovani BPK282A1 CBZ32257.1    
 LdCL_100021200   Leishmania donovani LdCL AYU76763.1    
 LdCL_100021300   Leishmania donovani LdCL AYU76764.1    
 LdCL_100020900   Leishmania donovani LdCL AYU76760.1    
 LdCL_100021400   Leishmania donovani LdCL AYU76765.1    
 LdCL_100021100   Leishmania donovani LdCL AYU76762.1    
 LdCL_100021000   Leishmania donovani LdCL AYU76761.1    
 LdCL_100021500   Leishmania donovani LdCL AYU76766.1    
 ORF   Leishmania donovani LV9 AKK31189.1    
 LINF_100020400   Leishmania infantum CAC9459128.1    
 LINF_100020300   Leishmania infantum CAC9459109.1    
 LINF_100020800   Leishmania infantum CAC9459206.1    
 LINF_100020700   Leishmania infantum CAC9459186.1    
 LINF_100020600   Leishmania infantum CAC9459168.1    
 LINF_100020900   Leishmania infantum CAC9459226.1    
 LINF_100020500   Leishmania infantum CAC9459149.1    
 LINJ_10_1430   Leishmania infantum JPCM5 CAM66154.1    
 LINJ_10_1370   Leishmania infantum JPCM5 CAM66148.1    
 LINJ_10_1400   Leishmania infantum JPCM5 CAM66151.1    
 LINJ_10_1410   Leishmania infantum JPCM5 CAM66152.1    
 LINJ_10_1380   Leishmania infantum JPCM5 CAM66149.1    
 LINJ_10_1420   Leishmania infantum JPCM5 CAM66153.1    
 LINJ_10_1390   Leishmania infantum JPCM5 CAM66150.1    
 ORF   Leishmania infantum MHOM/00/97/3277 AKK31190.1    
 ORF   Leishmania major L1989/05 AKK31191.1    
 LMJF_10_1230   Leishmania major strain Friedlin CAJ03072.1
CAG9570113.1		    
 LMJF_10_1260   Leishmania major strain Friedlin CAJ03084.1
CAG9570116.1		   2B4W[A]
 LMJF_10_1280   Leishmania major strain Friedlin CAJ03093.1
CAG9570118.1		    
 LMJF_10_1240   Leishmania major strain Friedlin CAJ03073.1
CAG9570114.1		    
 LMJF_10_1270   Leishmania major strain Friedlin CAJ03088.1
CAG9570117.1		    
 LMJF_10_1290   Leishmania major strain Friedlin CAJ03098.1
CAG9570119.1		    
 LMJF_10_1250   Leishmania major strain Friedlin CAJ03078.1
CAG9570115.1		    
 ORF   Leishmania mexicana MHOM/BZ/82/BEL21 AKK31192.1    
 MTP1 (LMXM_10_1230) 2.4.1.374 Leishmania mexicana MHOM/GT/2001/U1103 CBZ24446.1
XP_003872964.1		 E9AND7 6Q4W[A,B]
 MTP2 (LMXM_10_1240) 2.4.1.374 Leishmania mexicana MHOM/GT/2001/U1103 XP_003872965.1
CBZ24447.1		 E9AND8 6Q4X[A,B]
6Q4Y[A,B]
6Q4Z[A,B]
 MTP3 (LMXM_10_1250) 2.4.1.374 Leishmania mexicana MHOM/GT/2001/U1103 XP_003872966.1
CBZ24448.1		 E9AND9  
 MTP6 (LMXM_10_1280) 2.4.1.374 Leishmania mexicana MHOM/GT/2001/U1103 CBZ24451.1
XP_003872969.1		 E9ANE2  
 MTP5 (LMXM_10_1270)   Leishmania mexicana MHOM/GT/2001/U1103 CBZ24450.1
XP_003872968.1		    
 MTP4 (LMXM_10_1260) 2.4.1.374 Leishmania mexicana MHOM/GT/2001/U1103 CBZ24449.1
XP_003872967.1		 E9ANE0 6Q50[A]
 MTP7 (LMXM_10_1290) 2.4.1.374 Leishmania mexicana MHOM/GT/2001/U1103 CBZ24452.1
XP_003872970.1		 E9ANE3  
 ORF   Leishmania panamensis MHOM/PA/71/LS94 AKK31193.1    
 LPMP_101220   Leishmania panamensis MHOM/PA/94/PSC-1 AIN96191.1    
 LPMP_101180   Leishmania panamensis MHOM/PA/94/PSC-1 AIN96187.1    
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