GlycosylTransferase Family 108

Activities in FamilyGDP-α-D-Manp: β-1,2-D-mannosyltransferase (EC
Mechanism inverting
NoteCreated after (Sernee et al., Cell Host & Microbe, 2019), in press [PMID=31513773]. The dual activity mannosyltransferases/phosphorylases of six Leishmania proteins allows the management of mannogen (storage polysacharride). Family evolutionary related the bacterial GH130 phosphorylases.
Statistics GenBank accession (479); Uniprot accession (0); PDB accession (6); 3D entries (4); cryst (0)

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