GlycosylTransferase Family 104

Activities in FamilydTDP-β-L-Rhap : arginine α-L-rhamnosyltransferase (EC 2.4.1.-)
Mechanism Inverting
NoteLassak et al. identified EarP as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-b-L-rhamnose as donor substrate (PMID=25686373). The results of this study were subsequently confirmed for Pseudomonas aeruginosa (PMID=26060278), Pseudomonas putida (PMID=28951478) and Neisseria meningitidis (PMID=26840407). In 2016, it has been shown for S. oneidensis (PMID=28451135) and P. aeruginosa (PMID=28451332) that the enzyme is an inverting glycosyltransferase, thus mediating the formation of an a-L-rhamnosidic linkage. A structural basis for the arginine glycosylation reaction was provided by Krafczyk, Macosek and coworkers by having solved the crystal structure of the GT-B folding EarP from P. putida and an accompanying biochemical analysis of the enzyme (PMID=28951478).
Statistics GenBank accession (2176); Uniprot accession (0); PDB accession (9); 3D entries (3); cryst (0)
All (2172) Bacteria (2172) Structure (3) Characterized (4)
| 1 | ... | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Sputw3181_2132   Shewanella sp. W3-18-1 ABM24960.1    
 CKQ84_19590   Shewanella sp. WE21 AVI67854.1    
 FM037_13080 (EarP)   Shewanella sp. YLB-06 QDO84000.1    
 FS418_14315 (EarP)   Shewanella sp. YLB-09 QFU22924.1    
 Swoo_2269   Shewanella woodyi ATCC 51908 ACA86550.1    
 Slit_2076   Sideroxydans lithotrophicus ES-1 ADE12304.1    
 M5M_15405   Simiduia agarivorans SA1 = DSM 21679 AFV00214.1    
 BWP33_00715   Simonsiella muelleri ATCC 29453 AUX60499.1    
 C6571_00535 (EarP)   Simplicispira suum SC1-8 AVO39987.1    
 EWH46_06300 (EarP)   Sphaerotilus natans subsp. sulfidivorans D-507 QEN00427.1    
 HWQ50_13275   Sphingomonas azotifigens ACR22 QLD80849.1    
 B18_27215   Sphingomonas echinoides B18 QLD77689.1    
 DZC31_19955 (EarP)   Stenotrophomonas rhizophila GA1 AXQ49130.1    
 SDENCHOL_20047   Sterolibacterium denitrificans Chol SMB26077.1    
 SFSGTM_20280   Sulfuriferula nivalis BBP01320.1    
 SFPGR_23130   Sulfuriferula plumbiphila Gro7 BBP04891.1    
 CAP31_10665   Sulfuriferula sp. AH1 ARU32095.1    
 SUTH_01567   Sulfuritalea hydrogenivorans sk43H DSM22779 BAO29363.1    
 FG381_03865   Sutterella faecalis KGMB03119 QDA54159.1    
 S6FBBBH3_15910 (fragment)   Sutterella megalosphaeroides 6FBBBH3 BBF23700.1    
 CAV20_02875   Taylorella equigenitalis 09-0932 ASY40634.1    
 CA604_03045   Taylorella equigenitalis 15-1587 ASY39115.1    
 CA605_02870   Taylorella equigenitalis 89-0490 ASY37647.1    
 B9Z30_02945   Taylorella equigenitalis 92-0972 ASY30342.1    
 CA943_02880   Taylorella equigenitalis 98-0554 ASY42069.1    
 NCTC11184_00590   Taylorella equigenitalis ATCC 35865 NCTC11184 VEG30731.1    
 CN03_13400   Thalassolituus oleivorans K188 APR67836.1    
 TOL_0961   Thalassolituus oleivorans MIL-1 CCU71397.1    
 R615_12580   Thalassolituus oleivorans R6-15 AHK16417.1    
 Tharo_0048   Thauera aromatica K172 AVR87000.1    
 AC731_014440   Thauera humireducens SgZ-1 AMO38030.1    
 CCZ27_20295   Thauera sp. K11 ATE61996.1    
 Tmz1t_0133   Thauera sp. MZ1T ACK52930.1    
 Tbd_0856   Thiobacillus denitrificans ATCC 25259 AAZ96809.1    
 THMIRHAS_11590   Thiomicrorhabdus sp. aks77 BBP45786.1    
 THMIRHAT_10080   Thiomicrorhabdus sp. AkT22 BBP43262.1    
 THIAE_04725   Thiomicrospira aerophila AL3 AHF01186.1    
 Thicy_0842   Thiomicrospira cyclica ALM1 AEG31614.1    
 THI_1398   Thiomonas arsenitoxydans 3As CAZ88085.1    
 Tint_1106   Thiomonas intermedia K12 ADG30496.1    
 BIO17B3_10521   Thiomonas sp. Bio17B3 VDY03745.1    
 THICB2_640084   Thiomonas sp. CB2 CDW95228.1
VDY18788.1
   
 TOC7_10517   Thiomonas sp. OC7 VDY11995.1    
 SUP16B3_20947   Thiomonas sp. Sup16B3 VDY09078.1    
 Tola_3148   Tolumonas auensis DSM 9187 ACQ94736.1    
 Tresu_2078   Treponema succinifaciens DSM 2489 AEB14948.1    
 Unknown280_2010   uncultured Spirochaetaceae bacterium QGT51509.1    
 EJN92_14450 (EarP)   Undibacterium parvum DSM 23061 AZP13091.1    
 EJG51_016830 (EarP)   Undibacterium piscinae S11R28 QJQ07207.1    
 UNDKW_3069   Undibacterium sp. KW1 BBB61342.1    
 UNDYM_3142   Undibacterium sp. YM2 BBB67395.1    
 CKY39_12080   Variovorax boronicumulans J1 ATA53873.1    
 GFK26_29635 (EarP)   Variovorax paradoxus 5C-2 QFZ86638.1    
 VAPA_1c18670   Variovorax paradoxus B4 AGU48975.1    
 GOQ09_09015 (EarP)   Variovorax paradoxus CSUSB QGW81722.1    
 Varpa_1955   Variovorax paradoxus EPS ADU36164.1    
 Vapar_1780   Variovorax paradoxus S110 ACS18430.1    
 VAR608DRAFT_6419   Variovorax sp. HW608 SCK59351.1    
 AX767_16780   Variovorax sp. PAMC 28711 AMM25824.1    
 E5CHR_01766   Variovorax sp. PBL-E5 VTU24309.1    
 H6CHR_04144   Variovorax sp. PBL-H6 VTU34138.1    
 H4CHR_04459   Variovorax sp. PBS-H4 VTU38557.1    
 C4F17_00315 (EarP)   Variovorax sp. PMC12 AVQ79505.1    
 RA8CHR_04368   Variovorax sp. RA8 VTU31474.1    
 SRS16CHR_01683   Variovorax sp. SRS16 VTU16082.1    
 WDL1CHR_01305   Variovorax sp. WDL1 VTV10301.1    
 VITFI_CDS2378   Vitreoscilla filiformis ATCC 15551 ASM78156.1    
 ADP71_07620 (fragment)   Vitreoscilla sp. C1 AUZ04516.1
AUZ04516.2
   
 PSELUDRAFT_0064   Vogesella sp. LIG4 SCK05098.1    
 GT347_19895 (EarP)   Xylophilus sp. KACC 21265 QHJ00047.1    
 AZF00_11365   Zhongshania aliphaticivorans SM2 AMO68862.1    
 C3497_14475 (EarP)   Zoogloeaceae bacteirum Par-f-2 AVZ80498.1    
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