Glycoside Hydrolase Family 99

Activities in Familyglycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130); mannan endo-1,2-α-mannanase (3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseUnclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786)
Catalytic Proton DonorGlu (experimental)
NoteCreated after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363
External resourcesCAZypedia;
Statistics GenBank accession (229); Uniprot accession (30); PDB accession (30); 3D entries (2); cryst (0)
| 1 | 2 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 LuPra_04144   Acidobacteria bacterium DSM 100886 AMY10901.1    
 At1D1460_43850   Agrobacterium tumefaciens 1D1460 AYM08626.1    
 CO731_01226   Aminobacter sp. MSH1 AWC21773.1    
 YIM_39930   Amycolatopsis sp. YIM 10 QFU93125.1    
 D1815_10990   Aquimarina sp. AD1 AXT56255.1    
 D1816_23440   Aquimarina sp. AD10 AXT63173.1    
 D1818_20890   Aquimarina sp. BL5 AXT53162.1    
 OJF2_46290   Aquisphaera giovannonii OJF2 QEH36069.1    
 DJ013_01705   Arcticibacterium luteifluviistationis SM1504 AWV96957.1    
 Btheta7330_00449   Bacteroides thetaiotaomicron 7330 ALJ40035.1    
 endo-α-1,2-mannosidase (BtGH99;BT3862) (BtGH99) 3.2.1.130
3.2.1.198
Bacteroides thetaiotaomicron VPI-5482 AAO78967.1
NP_812773.1
Q8A109 4ACY[A,B]
4ACZ[A,B]
4AD0[A,B,C,D]
 Bun01g_02270 (fragment)   Bacteroides uniformis NBRC 113350 BBK85857.1    
 FKZ68_10440   Bacteroides xylanisolvens H207 QDH54618.1    
 endo-α-1,2-mannosidase (BxGH99;EndoMan;BXY_34140) (BxGH99) 3.2.1.130
3.2.1.198
Bacteroides xylanisolvens XB1A CBK68409.1 D6D1V7 4AD1[A]
4AD2[A,B,C,D]
4AD3[A,B,C,D]
4AD4[A]
4AD5[A]
4UTF[A]
4V27[A]
4V28[A]
5LYR[A]
5M03[A]
5M17[A]
5M3W[A]
5M5D[A]
5MC8[A]
5MEL[A]
6FAM[A]
6FAR[A]
6FWG[A]
6FWI[A]
6FWJ[A]
6FWL[A]
6FWM[A]
6FWO[A]
6FWP[A]
6FWQ[A]
6HMG[A]
6HMH[A]
 Pr1d_36860   Bythopirellula goksoyri Pr1d QEG36372.1    
 Pr1d_40310   Bythopirellula goksoyri Pr1d QEG36695.1    
 CLDAP_14670   Caldilinea aerophila DSM 14535 = NBRC 104270 BAL99506.1    
 644968214   Chitinophaga pinensis DSM 2588 ACU63492.1    
 CK934_17660   Chitinophaga sp. MD30 ASZ12652.1    
 EGY05_19145   Chryseobacterium arthrosphaerae FDAARGOS_519 AYZ13922.1    
 EG339_03120   Chryseobacterium bernardetii G0229 AZB23683.1    
 EG351_12080   Chryseobacterium bernardetii H4638 AZB34285.1    
 EG345_00145   Chryseobacterium carnipullorum F9942 AZA63289.1    
 EG346_09240   Chryseobacterium carnipullorum G0188 AZA48356.1    
 OK18_05290   Chryseobacterium gallinarum DSM 27622 AKK72127.1    
 DDI74_11285   Chryseobacterium gleum 110146 QBJ86806.1    
 NCTC11432_02793   Chryseobacterium gleum NCTC11432 VEE08661.1    
 EU348_02070   Chryseobacterium indologenes StR 01 QBA20017.1    
 EG359_12225   Chryseobacterium joostei DSM 16927 AZB00339.1    
 EG343_11535   Chryseobacterium nakagawai G0041 AZA91221.1    
 NCTC13529_04913   Chryseobacterium nakagawai NCTC13529 VEH22787.1    
 EG344_14000   Chryseobacterium sp. G0162 AZB11819.1    
 EG347_11820   Chryseobacterium sp. G0186 AZA78153.1    
 CHSO_4479   Chryseobacterium sp. StRB126 BAP33516.1    
 D4L85_32505   Chryseolinea sp. KIS68-18 AYB35017.1    
 CYFUS_004517   Cystobacter fuscus DSM 52655 ATB39078.1    
 Deba_3244   Desulfarculus baarsii DSM 2075 ADK86597.1 E1QM12  
 D1013_13780   Euzebyella marina RN62 AYN68372.1    
 OP10G_1502   Fimbriimonas ginsengisoli Gsoil 348 AIE84870.1    
 EI427_22690   Flammeovirga sp. L12M1 AZQ65031.1    
 D770_00985   Flammeovirgaceae bacterium 311 AHM58471.1    
 HYN56_21320   Flavobacterium crocinum HYN0056 AWK06632.1    
 FFWV33_08520   Flavobacterium faecale WV33 AWG21571.1    
 BB050_03160   Flavobacterium johnsoniae GSE09 AOC96249.1    
 Fjoh_4327   Flavobacterium johnsoniae UW101 ABQ07335.1    
 HYN49_08890   Flavobacterium pallidum HYN0049 AWI26003.1    
 ALW18_03240   Flavobacterium psychrophilum Z1 AOE54296.1    
 AMR72_03240   Flavobacterium psychrophilum Z2 ALM50674.1    
 HYN86_17750   Flavobacterium sp. HYN0086 AXB58340.1    
 B0M43_0020470   Flavobacterium sp. KBS0721 QDW22397.1    
 FUA48_08145   Flavobacterium sp. XS-5 QEE49551.1    
 Haur_3007   Herpetosiphon aurantiacus DSM 785 ABX05645.1    
 FHG12_04195   Hymenobacter sp. 17J68-5 QDA59353.1    
 GJA_1091   Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628 CDG81746.1    
 ORF   Kibdelosporangium sp. MJ126-NF4 CTQ91594.1    
 Kole_0482   Kosmotoga olearia TBF 19.5.1 ACR79205.1 C5CEA1  
 EPA93_38735   Ktedonobacterales bacterium SCAWS-G2 QBD81593.1    
 LA76x_2943 (ManeA)   Lysobacter antibioticus 76 ALN81073.1    
 LA76x_0982   Lysobacter antibioticus 76 ALN79143.1    
 GLA29479_246   Lysobacter antibioticus ATCC 29479 ALN61132.1    
 GLA29479_2173   Lysobacter antibioticus ATCC 29479 ALN63043.1    
 C9I47_2704   Lysobacter maris HZ9B AWV08380.1    
 FKV23_02920   Lysobacter sp. SJ-36 QDH69163.1    
 MFFC18_04220   Mariniblastus fucicola FC18 QEG20573.1    
 MEBOL_003633   Melittangium boletus DSM 14713 ATB30178.1    
 BN4615_P5528   Nonomuraea gerenzanensis ATCC 39727 SBO96012.1    
 AY601_2188   Pedobacter cryoconitis PAMC 27485 AMP99086.1    
 CPT03_06560   Pedobacter ginsengisoli T01R-27 ATP56149.1    
 STSP2_03000   Phycisphaerae bacterium ST-NAGAB-D1 AQT69803.1    
 PLANPX_0769   Planctomycetales bacterium PX69 BBO31157.1    
 PLANPX_5437   Planctomycetales bacterium PX69 BBO35825.1    
 Enr10x_27000   Planctomycetes bacterium Enr10 QDT27383.1    
 HG66A1_22370   Planctomycetes bacterium HG66A1 QDT20451.1    
 K2D_21900   Planctomycetes bacterium K2D QDV78583.1    
 K2D_27510   Planctomycetes bacterium K2D QDV79140.1    
 KS4_30670   Planctomycetes bacterium KS4 QDU34990.1    
 KS4_13410   Planctomycetes bacterium KS4 QDU33295.1    
 Mal4_55290   Planctomycetes bacterium Mal4 QDU41164.1    
 MalM14_28150   Planctomycetes bacterium MalM14 QDT85148.1    
 MalM25_22120   Planctomycetes bacterium MalM25 QDT69276.1    
 Pan265_03950   Planctomycetes bacterium Pan265 QDU70567.1    
 Pan265_03990   Planctomycetes bacterium Pan265 QDU70571.1    
 Spa11_27040   Planctomycetes bacterium Spa11 QDV74500.1    
 Spa11_21520   Planctomycetes bacterium Spa11 QDV73953.1    
 SV7mr_05200   Planctomycetes bacterium SV_7m_r QDT58031.1    
 V144x_37410   Planctomycetes bacterium V144 QDT98255.1    
 V202x_28190   Planctomycetes bacterium V202 QDU09444.1    
 V6x_22780   Planctomycetes bacterium V6 QDU02573.1    
 BW723_17595   Polaribacter reichenbachii 6Alg 8T APZ47999.1    
 BW723_17590   Polaribacter reichenbachii 6Alg 8T APZ47998.1    
 BTO17_08005   Polaribacter reichenbachii KCTC 23969 AUC18633.1    
 BTO17_08000   Polaribacter reichenbachii KCTC 23969 AUC18632.1    
 CRM71_08335   Prevotella jejuni CD3_33 AUI55491.1    
 HMPREF0659_A6411   Prevotella melaninogenica ATCC 25845 ADK95453.1 D9RT77  
 CEP85_00160   Prevotella melaninogenica FDAARGOS_306 ASE16633.1    
 PMEL1_01415   Prevotella melaninogenica GAI 07411 BBA29477.1    
 AXF22_01650   Prevotella scopos JCM 17725 ANR73274.1    
 Plabr_4762   Rubinisphaera brasiliensis DSM 5305 ADY62333.1    
 STSP1_00024   Sedimentisphaera salicampi ST-PulAB-D4 ARN55664.1    
 endo-α-1,2-mannosidase (Sama99;Sama_0297) 3.2.1.130 Shewanella amazonensis SB2B ABL98508.1 A1S2A2  
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