Known Activities	glycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130)
Mechanism	Retaining
3D Structure Status	( β / α ) 8
Catalytic Nucleophile/Base	Unclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786)
Catalytic Proton Donor	Glu (experimental)
Note	Created after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363
External resources	CAZypedia;
Statistics	GenBank accession (83); Uniprot accession (28); PDB accession (8); 3D entries (2); cryst (0)

Archaea
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
APE_0727 (fragment)		Aeropyrum pernix K1	BAA79703.1
Pars_1633		Pyrobaculum arsenaticum DSM 13514	ABP51186.1
Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
endo-α-1,2-mannosidase (BXY_34140) (BxGH99)	3.2.1.130	Bacteriodes xylanisolvens XB1A	CBK68409.1	D6D1V7	4AD1 4AD2 4AD3 4AD4 4AD5
endo-α-1,2-mannosidase (BT3862) (BtGH99)	3.2.1.130	Bacteroides thetaiotaomicron VPI-5482	AAO78967.1 NP_812773.1		4ACY 4ACZ 4AD0
Deba_3244		Desulfarculus baarsii DSM 2075	ADK86597.1	E1QM12
Haur_3007		Herpetosiphon aurantiacus ATCC 23779	ABX05645.1
Plabr_4762		Planctomyces brasiliensis DSM 5305	ADY62333.1
HMPREF0659_A6411		Prevotella melaninogenica ATCC 25845	ADK95453.1	D9RT77
endo-α-1,2-mannosidase (Sama99;Sama_0297)	3.2.1.130	Shewanella amazonensis SB2B	ABL98508.1	A1S2A2
STHERM_c15300		Spirochaeta thermophila DSM 6192	ADN02470.1	E0RTU5
Spith_1563		Spirochaeta thermophila DSM 6578	AEJ61824.1
STAUR_3309		Stigmatella aurantiaca DW4/3-1	ADO71101.1	Q08X64
SBI_00635		Streptomyces bingchenggensis BCW-1	ADI03756.1	D7C2A2
SBI_09400		Streptomyces bingchenggensis BCW-1	ADI12518.1	D7C5Y9
SGR_5090		Streptomyces griseus subsp. griseus NBRC 13350	BAG21919.1	B1VYD4
Strvi_5963		Streptomyces violaceusniger Tu 4113	AEM85470.1
Sros_3784		Streptosporangium roseum DSM 43021	ACZ86705.1	D2ATI5
Kole_0482		Thermotogales bacterium TBF 19.5.1	ACR79205.1	C5CEA1
Trebr_0184		Treponema brennaborense DSM 12168	AEE15635.1
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
ENSANGG00000018734 (fragment)		Anopheles gambiae str. PEST	EAA00122.2 XP_320623.1
ORF (fragment)		Ascaris suum	ADY46293.1
endo-α-mannosidase (protein for IMAGE:7984259) (fragment)		Bos taurus	AAI03139.1 AEM43818.1	Q3ZBS4
Unknown (protein for MGC:152422)		Bos taurus	AAI51267.1	A7MB02
endomannosidase		Cricetulus griseus	ABH07382.1	A7RDN7
Manea (fragment)		Danio rerio	AAH81681.1	Q66HT9
CH211-30B16.2-001		Danio rerio	CAK04938.1	Q1L8D2
CG14015		Drosophila melanogaster	AAF52260.2 AAL49145.1 NP_608937.1	Q9VMQ2
GA12699		Drosophila pseudoobscura MV2-25	EAL34552.1
LOC421807		Gallus gallus	XP_419831.1
LOC419611		Gallus gallus	XP_417758.1
glycoprotein endo-α-1,2-mannosidase (ManeA)	3.2.1.130	Homo sapiens	AAI46672.1 AAI50200.1 AAL07306.1 AAL07307.1 AAQ75077.1 ACH33940.1 BAB14298.1 BAF84629.1 CAD97640.1 CAE12165.1 CAE45927.1 CAH33902.1 CAI17346.1 CAI17347.1 NP_078917.2	A6H8M6 Q5SRI9
Rp11-109p14.3		Homo sapiens	AAH09952.2 AAH31903.1 AAH63587.1 AAH77730.1 ABE14780.1 BAB71068.1 BAG62934.1 CAH70081.1 CAH70082.1 NP_689709.1	Q5VSG8
Manea		Mus musculus	AAH67076.1 BAC26805.1 CAM23963.1 NP_766453.2	Q6NXH2
Gm50 (ManeaL)		Mus musculus	AAH65047.1 BAE23227.1 CAM16102.1	Q6P1J0
ORF		Mustela putorius furo	AES01516.1
ORF (fragment)		Mustela putorius furo	AES01517.1
ORF (fragment)		Mustela putorius furo	AES01518.1
LOC472074		Pan troglodytes	XP_527453.1
DKFZp469G135		Pongo abelii	CAH90264.1	Q5RD93
endo-α-1,2-mannosidase (Enman)	3.2.1.130	Rattus norvegicus	AAB86925.1 AAT44962.1 NP_542963.1 XP_346734.1	Q5GF25
LOC366466 (fragment)		Rattus norvegicus	XP_345581.1
Smp_016880		Schistosoma mansoni	CAZ29389.1 CCD80792.1	C4Q1N7
GSTEN:00031982:G:001		Tetraodon nigroviridis	CAG10373.1	Q4RMK9
Unknown (protein for MGC:121847)		Xenopus (Silurana) tropicalis	AAI35933.1 AAI52045.1	A4IIA4
Maneα-prov		Xenopus laevis	AAH77304.1	Q6DE40

Last update: 2012-01-31 © Copyright 1998-2012
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