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Glycoside Hydrolase Family 99

Activities in FamilyGlycoprotein endo-α-1,2-mannosidase (EC 3.2.1.130);
Mannan endo-1,2-α-mannanase (EC 3.2.1.198);
Mechanism Retaining a
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseUnclear, possible neighboring group participation from O2 (after Thompson et al. Proc. Natl. Acad. Sci. USA., 2012, 109, 781-786)
Catalytic Proton DonorGlu (experimental)
NoteCreated after Spiro, Bhoyroo and Spiro (1997) J. Biol. Chem. 272, 29356-29363
External resourcesCAZypedia;
Statistics GenBank accession (518); Uniprot accession (7); PDB accession (40); 3D entries (3); cryst (0)
Summary
Download GH99 (512) Taxonomic display Structure (3) Characterized (5)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ACAM_0412   Aeropyrum camini SY1 = JCM 12091 BAN89881.1    
 APE_0727 (fragment)   Aeropyrum pernix K1 BAA79703.1    
 J4526_08045   Desulfurococcaceae archaeon MEX13E-LK6-19 WFO75013.1    
 J4526_06460   Desulfurococcaceae archaeon MEX13E-LK6-19 WFO74718.1    
 HALDL1_09485   Halobacterium sp. DL1 AHG05266.1    
 K6T25_15470   Halobaculum rubrum C46 QZY01185.1    
 HPS36_15655   Halorubrum salinarum RHB-C QKG94318.1    
 M0R88_06185   Halorussus gelatinilyticus XZYJT40 UPW01686.1    
 Pars_1633   Pyrobaculum arsenaticum DSM 13514 ABP51186.1    
 PABY_02070   Pyrodictium abyssi AV2 BES80640.1    
 L593_09755   Salinarchaeum sp. Harcht-Bsk1 AGN01896.1    
 A3L01_02480   Thermococcus barossii SHCK-94 ASJ04282.1    
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 LuPra_04144   Acidobacteria bacterium DSM 100886 AMY10901.1    
 LCL61_29230   Amycolatopsis coloradensis BCA-696 WYW19635.1    
 QRX60_50605   Amycolatopsis mongoliensis 4-36 WIY02156.1    
 MUY14_03015   Amycolatopsis pretoriensis FBCC-B4732 UOX89624.1    
 QP939_29310   Amycolatopsis sp. 2-2 WIV53019.1    
 MUY22_48680   Amycolatopsis sp. WQ 127309 UOZ06587.1    
 YIM_39930   Amycolatopsis sp. YIM 10 QFU93125.1    
 STSP2_03000   Anaerohalosphaera lusitana ST-NAGAB-D1 AQT69803.1    
 D1815_10990   Aquimarina sp. AD1 AXT56255.1    
 D1816_23440   Aquimarina sp. AD10 AXT63173.1    
 D1818_20890   Aquimarina sp. BL5 AXT53162.1    
 OJF2_46290   Aquisphaera giovannonii OJF2 QEH36069.1    
 F0U60_40670   Archangium minus Cbm 6 WNG49737.1    
 F0U61_40390   Archangium violaceum Cbvi 34 WNG39237.1    
 JQX13_00745   Archangium violaceum SDU34 QRK08748.1    
 JRI60_31015   Archangium violaceum SDU8 QRN93594.1    
 V7P26_00570 (fragment)   Arcobacter sp. AZ-2023 Kiel 2759 WWW11929.1    
 K6V21_06605   Bacteroides cellulosilyticus BFG-250 UBD71079.1    
 K6V30_07760   Bacteroides faecis BFG-108 UBE46689.1    
 NXY30_08670   Bacteroides faecis BFG-527 UVQ76423.1    
 NXW58_09565   Bacteroides faecis BFG-624 UVP35070.1    
 RJT06_22110   Bacteroides ovatus H-1813 MDV3119213.1    
 NXV86_06965   Bacteroides sp. BFG-257 UVO99719.1    
 H8796_12000   Bacteroides sp. M10 QNL36596.1    
 Btheta7330_00449   Bacteroides thetaiotaomicron 7330 ALJ40035.1    
 NFE52_08525   Bacteroides thetaiotaomicron B2 WWE56353.1    
 NXV79_07825   Bacteroides thetaiotaomicron BFG-109 UVP62282.1    
 NXX00_08445   Bacteroides thetaiotaomicron BFG-116 UVV82080.1    
 NXY23_07980   Bacteroides thetaiotaomicron BFG-119 UVS54918.1    
 NXX57_08265   Bacteroides thetaiotaomicron BFG-129 UVP57843.1    
 NXV61_09360   Bacteroides thetaiotaomicron BFG-130 UVR93170.1    
 NXX60_13690   Bacteroides thetaiotaomicron BFG-148 UVQ21078.1    
 NXY45_08365   Bacteroides thetaiotaomicron BFG-169 UVP43853.1    
 NXX51_07925   Bacteroides thetaiotaomicron BFG-264 UVS14574.1    
 NXY38_08410   Bacteroides thetaiotaomicron BFG-266 UVV86564.1    
 NXY15_10400   Bacteroides thetaiotaomicron BFG-357 UVV54528.1    
 NXW43_08240   Bacteroides thetaiotaomicron BFG-446 UVO75313.1    
 NXY16_08315   Bacteroides thetaiotaomicron BFG-478 UVS27006.1    
 NXW22_08455   Bacteroides thetaiotaomicron BFG-484 UVP30310.1    
 NXV46_08770   Bacteroides thetaiotaomicron BFG-498 UVQ43725.1    
 NXY28_13290 (fragment)   Bacteroides thetaiotaomicron BFG-505 UVV60882.1    
 NXY28_13285 (fragment)   Bacteroides thetaiotaomicron BFG-505 UVV60881.1    
 NXW82_09230   Bacteroides thetaiotaomicron BFG-510 UVQ28891.1    
 K6V27_07730   Bacteroides thetaiotaomicron BFG-55 UBD13474.1    
 NXX83_09130   Bacteroides thetaiotaomicron BFG-576 UVQ71348.1    
 INE82_00336   Bacteroides thetaiotaomicron CL06T03C18 QUT69577.1    
 INE89_03959   Bacteroides thetaiotaomicron CL11T00C24 QUT41737.1    
 KHO74_02992   Bacteroides thetaiotaomicron CL15T119C52 QZU86997.1    
 KHO73_02982   Bacteroides thetaiotaomicron CL15T12C11 QZU81572.1    
 V3C11_08680   Bacteroides thetaiotaomicron DFI.6.40 WVP68938.1    
 FE838_09215   Bacteroides thetaiotaomicron DSM 2079 QMW86225.1    
 BatF92_03560   Bacteroides thetaiotaomicron F9-2 BCA48414.1    
 I6G92_21785   Bacteroides thetaiotaomicron FDAARGOS_935 QQA08026.1    
 RJT07_17345   Bacteroides thetaiotaomicron H-2209 WOG18911.1    
 RJT03_10315   Bacteroides thetaiotaomicron H-2622 WOG40950.1    
 MJ393_08625   Bacteroides thetaiotaomicron VPI 5482 UML63116.1    
 KQP69_03415   Bacteroides thetaiotaomicron VPI-2808B UYV01328.1    
 KQP56_13320   Bacteroides thetaiotaomicron VPI-3164 UYU93622.1    
 KQP74_24440   Bacteroides thetaiotaomicron VPI-3443 UYU91028.1    
 endo-α-1,2-mannosidase (BtGH99;BT3862) (BtGH99) 3.2.1.130
3.2.1.198		 Bacteroides thetaiotaomicron VPI-5482 AAO78967.1
NP_812773.1		 Q8A109 4ACY[A,B]
4ACZ[A,B]
4AD0[A,B,C,D]
 KP721_22400   Bacteroides thetaiotaomicron VPI-5482A UYU85896.1    
 KQP77_15790   Bacteroides thetaiotaomicron VPI-BT7853 UYU79940.1    
 KQP72_17895   Bacteroides thetaiotaomicron VPI-BT8702 UYU74940.1    
 KQP59_06680   Bacteroides thetaiotaomicron VPI-BTDOT2 UYU72783.1    
 KQP68_22710   Bacteroides thetaiotaomicron WAL8669 UYU66334.1    
 KQP65_12120   Bacteroides thetaiotaomicron WAL8713 UYU64072.1    
 Bun01g_02270 (fragment)   Bacteroides uniformis NBRC 113350 BBK85857.1    
 FQN58_00780   Bacteroides xylanisolvens APCS1/XY QUR41867.1    
 P2T61_04260   Bacteroides xylanisolvens AY11-1 WET86890.1    
 NXW81_11075   Bacteroides xylanisolvens BFG-319 UVQ13208.1    
 NXX95_11785   Bacteroides xylanisolvens BFG-514 UVP26465.1    
 NXX35_11905   Bacteroides xylanisolvens BFG-566 UVR76010.1    
 INE92_05119   Bacteroides xylanisolvens CL11T00C03 QUT33051.1    
 INE93_04984   Bacteroides xylanisolvens CL11T00C41 QUT27489.1    
 FKZ68_10440   Bacteroides xylanisolvens H207 QDH54618.1    
 endo-α-1,2-mannosidase (BxGH99;EndoMan;BXY_34140) (BxGH99) 3.2.1.130
3.2.1.198		 Bacteroides xylanisolvens XB1A CBK68409.1 D6D1V7 4AD1[A]
4AD2[A,B,C,D]
4AD3[A,B,C,D]
4AD4[A]
4AD5[A]
4UTF[A]
4V27[A]
4V28[A]
5LYR[A]
5M03[A]
5M17[A]
5M3W[A]
5M5D[A]
5MC8[A]
5MEL[A]
6FAM[A]
6FAR[A]
6FWG[A]
6FWI[A]
6FWJ[A]
6FWL[A]
6FWM[A]
6FWO[A]
6FWP[A]
6FWQ[A]
6HMG[A]
6HMH[A]
6ZJ6[AAA]
 M4951_01150   Blastopirellula sp. J2-11 UUO06933.1    
 Spa11_27040   Botrimarina mediterranea Spa11 QDV74500.1    
 Spa11_21520   Botrimarina mediterranea Spa11 QDV73953.1    
 Pr1d_36860   Bythopirellula goksoeyrii Pr1d QEG36372.1    
 Pr1d_40310   Bythopirellula goksoeyrii Pr1d QEG36695.1    
 CLDAP_14670   Caldilinea aerophila DSM 14535 = NBRC 104270 BAL99506.1    
 OZ401_001179   Chloroflexota bacterium L227-S17 WJW67895.1    
 Q2T83_02885   Candidatus Fervidibacter sacchari PD1 WKU16778.1    
 CCAX7_44090   Capsulimonas corticalis AX-7 BDI32358.1    
 CS0771_34330   Catellatospora sp. IY07-71 BCJ73889.1    
 GWR21_10375   Chitinophaga agri H33E-04 QHS59984.1    
 MYF79_12995   Chitinophaga filiformis YT5 UPK72203.1    
 KTO58_11225   Chitinophaga pendula MD30B UCJ09737.1    
 644968214   Chitinophaga pinensis DSM 2588 ACU63492.1    
 SR876_26645   Chitinophaga sancti ATCC 23090 WQG88507.1    
 U0033_15825   Chitinophaga sancti HAMBI_1988 WQD65871.1    
 SIO70_32495   Chitinophaga sancti HSF-01 WPQ63088.1    
 QQL36_02465   Chitinophaga sp. LS1 WPV67586.1    
 CK934_17660   Chitinophaga sp. MD30 ASZ12652.1    
 EGY05_19145   Chryseobacterium arthrosphaerae FDAARGOS_519 AYZ13922.1    
 P2W68_13585   Chryseobacterium arthrosphaerae FS91703 WES95883.1    
 J8N07_13190   Chryseobacterium arthrosphaerae LMY UEQ74629.1    
 I2F65_17945   Chryseobacterium arthrosphaerae SQ099 QUY54742.1    
 EG339_03120   Chryseobacterium bernardetii G0229 AZB23683.1    
 EG351_12080   Chryseobacterium bernardetii H4638 AZB34285.1    
 H5J24_00770   Chryseobacterium capnotolerans DH-B6 UHO38768.1    
 EG345_00145   Chryseobacterium carnipullorum F9942 AZA63289.1    
 EG346_09240   Chryseobacterium carnipullorum G0188 AZA48356.1    
 JNG87_02420   Chryseobacterium cucumeris MW-6 QRA43625.1    
 MUU74_07360   Chryseobacterium daecheongense F23 UOU99766.1    
 OK18_05290   Chryseobacterium gallinarum DSM 27622 AKK72127.1    
 FOB44_16545   Chryseobacterium gallinarum FDAARGOS_636 QIY92168.1    
 DDI74_11285   Chryseobacterium gleum 110146 QBJ86806.1    
 I6I60_06810   Chryseobacterium gleum FDAARGOS_1103 QQY33478.1    
 NCTC11432_02793   Chryseobacterium gleum NCTC11432 VEE08661.1    
 PYS58_13285   Chryseobacterium indologenes Ery-6B WET47551.1    
 EU348_02070   Chryseobacterium indologenes StR 01 QBA20017.1    
 EG359_12225   Chryseobacterium joostei DSM 16927 AZB00339.1    
 EG343_11535   Chryseobacterium nakagawai G0041 AZA91221.1    
 NCTC13529_04913   Chryseobacterium nakagawai NCTC13529 VEH22787.1    
 N0B40_18340   Chryseobacterium oranimense 33-M-3 UWX60345.1    
 KB553_12775   Chryseobacterium rhizoplanae XL97 UCA57929.1    
 KYG33_12135   Chryseobacterium sp. D764 QXU47561.1    
 EG344_14000   Chryseobacterium sp. G0162 AZB11819.1    
 EG347_11820   Chryseobacterium sp. G0186 AZA78153.1    
 SFA27_02535   Chryseobacterium sp. HR92 WPO91571.1    
 CHRYMOREF3P_2369   Chryseobacterium sp. JV274 F3_Prior CAD0221633.1    
 KIK00_12830   Chryseobacterium sp. MA9 UTX46839.1    
 LF887_21105   Chryseobacterium sp. MEBOG06 UKB83478.1    
 LF886_04085   Chryseobacterium sp. MEBOG07 UKB80192.1    
 KBP46_17770   Chryseobacterium sp. PCH239 QWT85300.1    
 RHP76_12555   Chryseobacterium sp. SG20098 WNI34811.1    
 CHSO_4479   Chryseobacterium sp. StRB126 BAP33516.1    
 PZ898_12395   Chryseobacterium sp. WX WFB65540.1    
 D4L85_32505   Chryseolinea soli KIS68-18 AYB35017.1    
 F0U63_21970   Cystobacter fuscus Cbf 10 WNG17034.1    
 F0U62_23075   Cystobacter fuscus Cbf 8 WNG26576.1    
 CYFUS_004517   Cystobacter fuscus DSM 52655 ATB39078.1    
 Daura_25885   Dactylosporangium aurantiacum NRRL B-8018 UWZ50281.1    
 KZZ52_13875   Dactylosporangium sp. AC04546 WVK86414.1    
 Deba_3244   Desulfarculus baarsii DSM 2075 ADK86597.1    
 DCPSUM001_10880   Dysgonomonas capnocytophagoides SMU001 BES60844.1    
 G7050_05950   Dysgonomonas sp. HDW5A QIK59402.1    
 G7051_06215   Dysgonomonas sp. HDW5B QIK53953.1    
 D1013_13780   Euzebyella marina RN62 AYN68372.1    
 K9M53_11525   Ferruginibacter albus KIS38-8 UAY51218.1    
 K9M53_06435   Ferruginibacter albus KIS38-8 UAY53303.1    
 K9M53_11505   Ferruginibacter albus KIS38-8 UAY51214.1    
 LK994_10620   Ferruginibacter lapsinanis KACC 15035 UEG49083.1    
 LK994_10595   Ferruginibacter lapsinanis KACC 15035 UEG49078.1    
 OP10G_1502 (fragment)   Fimbriimonas ginsengisoli Gsoil 348 AIE84870.1    
 KM029_23415   Flammeovirga kamogawensis YS10 QWG09560.1    
 EI427_22690   Flammeovirga pectinis L12M1 AZQ65031.1    
 D770_00985   Flammeovirgaceae bacterium 311 AHM58471.1    
 FUA48_08145   Flavobacterium alkalisoli XS-5 QEE49551.1    
 LLY39_18640   Flavobacterium anhuiense T4 URM36413.1    
 L0669_19475   Flavobacterium bizetiae HJ-32-4 UTN03505.1    
 HYN56_21320   Flavobacterium crocinum HYN0056 AWK06632.1    
 J0383_20000   Flavobacterium endoglycinae BB8 QSW88512.1    
 FFWV33_08520   Flavobacterium faecale WV33 AWG21571.1    
 HYN86_17750   Flavobacterium fluviale HYN0086 AXB58340.1    
 V6624_20160   Flavobacterium ginsenosidimutans YTB16 WXK49341.1    
 M0M44_20350   Flavobacterium humidisoli MMS21-Er5 UPZ15100.1    
 NYQ10_20380   Flavobacterium johnsoniae G16 WJS94444.1    
 BB050_03160   Flavobacterium johnsoniae GSE09 AOC96249.1    
 Fjoh_4327   Flavobacterium johnsoniae UW101 ABQ07335.1    
 SR927_22800   Flavobacterium johnsoniae UW101 ATCC 17061 WQG80831.1    
 HYN49_08890   Flavobacterium pallidum HYN0049 AWI26003.1    
 NLJ00_21285   Flavobacterium panici BSSL-CR3 UUF13796.1    
 Q1W71_07135   Flavobacterium pectinovorum ZE23VCel01 WKL49559.1    
 NLG42_19205   Flavobacterium plurextorum RSG-18 UUW08224.1    
 ALW18_03240   Flavobacterium psychrophilum Z1 AOE54296.1    
 AMR72_03240   Flavobacterium psychrophilum Z2 ALM50674.1    
 AABD74_18540   Flavobacterium soyae 55 WYZ19155.1    
 HAV12_009000   Flavobacterium sp. CLA17 QSB28852.1    
 FLGSB24_36300   Flavobacterium sp. GSB-24 BDU26886.1    
 PQ462_15205   Flavobacterium sp. KACC 22758 WDF58065.1    
 SCB73_19995   Flavobacterium sp. KACC 22761 WPO78548.1    
 PQ463_09770   Flavobacterium sp. KACC 22763 WDF66441.1    
 B0M43_0020470   Flavobacterium sp. KBS0721 QDW22397.1    
 IHE43_11510   Flavobacterium sp. MDT1-60 QOG04772.1    
 GIY83_04210   Flavobacterium sp. SLB02 SGTM QGK73289.1    
 N4T20_17875   Flavobacterium sp. TR2 UWY27588.1    
 MH928_12290   Flavobacterium sp. WW92 WDO12103.1    
 P0R33_18900   Flavobacterium sp. YJ01 WET01826.1    
 V144x_37410   Gimesia aquarii V144 QDT98255.1    
 F1728_03455   Gimesia benthica E7 QGQ21802.1    
 Enr10x_27000   Gimesia panareensis Enr10 QDT27383.1    
 Haur_3007   Herpetosiphon aurantiacus DSM 785 ABX05645.1    
 OIS53_19190   Hymenobacter sp. YIM 151500-1 UYZ63106.1    
 GJA_1091   Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628 CDG81746.1    
 ORF   Kibdelosporangium sp. MJ126-NF4 CTQ91594.1    
 RGQ21_15920   Kitasatospora aureofaciens Tu117 BET46610.1    
 Kole_0482   Kosmotoga olearia TBF 19.5.1 ACR79205.1    
 ccbrp13_36020   Ktedonobacteria bacterium brp13 BCL81137.1    
 EPA93_38735   Ktedonosporobacter rubrisoli SCAWS-G2 QBD81593.1    
 JJ691_00670   Kutzneria sp. CA-103260 QUQ62355.1    
 TBR22_30140   Luteitalea sp. TBR-22 BCS33817.2
BCS33817.1		    
 KBB96_05790   Luteolibacter ambystomatis 32A QUE52401.1    
 FKV23_02920   Lysobacter alkalisoli SJ-36 QDH69163.1    
 LA76x_2943 (ManeA)   Lysobacter antibioticus 76 ALN81073.1    
 LA76x_0982   Lysobacter antibioticus 76 ALN79143.1    
 GLA29479_246   Lysobacter antibioticus ATCC 29479 ALN61132.1    
 GLA29479_2173   Lysobacter antibioticus ATCC 29479 ALN63043.1    
 C9I47_2704   Lysobacter maris HZ9B AWV08380.1    
 LVB77_18050   Lysobacter sp. 5GHs7-4 UHQ22536.1    
 Mal4_55290   Maioricimonas rarisocia Mal4 QDU41164.1    
 MFFC18_04220   Mariniblastus fucicola FC18 QEG20573.1    
 MEBOL_003633   Melittangium boletus DSM 14713 ATB30178.1    
 HXZ27_18640   Micromonospora carbonacea aurantiaca QLD25982.1    
 PVK37_11915   Micromonospora sp. HUAS 3 WDZ87050.1    
 H1D33_11835   Micromonospora ferruginea 28ISP2-46 QLQ39452.1    
 RMN56_26270   Micromonospora halotolerans DSM 45598 WNM38608.1    
 O7633_03795   Micromonospora sp. WMMD712 WFE56038.1    
 O7606_13310   Micromonospora sp. WMMD882 WBB77278.1    
 PQO05_05435   Mucilaginibacter jinjuensis KACC 16571 WCT13375.1    
 Pan265_03950   Mucisphaera calidilacus Pan265 QDU70567.1    
 Pan265_03990   Mucisphaera calidilacus Pan265 QDU70571.1    
 LV483_48830   Myxococcales bacterium MSr11368 WXA83828.1    
 G7071_01355   Nocardioides piscis HDW12A QIK74283.1    
 BN4615_P5528   Nonomuraea gerenzanensis ATCC 39727 SBO96012.1    
 LCN96_25185   Nonomuraea gerenzanensis L70 UBU18197.1    
 L1F29_18470   Paenibacillus spongiae PHS-Z3 UVI27456.1    
 AY601_2188   Pedobacter cryoconitis PAMC 27485 AMP99086.1    
 CPT03_06560   Pedobacter ginsengisoli T01R-27 ATP56149.1    
 G4Y79_00285   Phototrophicus methaneseepsis ZRK33 QPC82847.1    
 G4Y79_02790   Phototrophicus methaneseepsis ZRK33 QPC83322.1    
 IPV69_13860   Phycisphaerales bacterium M1803 QOV87376.1    
 Pflav_004350   Phytohabitans flavus NBRC 107702 BCB74025.1    
 Pflav_039300 (fragment)   Phytohabitans flavus NBRC 107702 BCB77520.1    
 PLANPX_0769   Planctomycetales bacterium PX69 BBO31157.1    
 PLANPX_5437   Planctomycetales bacterium PX69 BBO35825.1    
 HG66A1_22370   Planctomycetes bacterium HG66A1 QDT20451.1    
 K2D_21900   Planctomycetes bacterium K2D QDV78583.1    
 K2D_27510   Planctomycetes bacterium K2D QDV79140.1    
 MalM14_28150   Planctomycetes bacterium MalM14 QDT85148.1    
 MalM25_22120   Planctomycetes bacterium MalM25 QDT69276.1    
 SV7mr_05200   Planctomycetes bacterium SV_7m_r QDT58031.1    
 V202x_28190   Planctomycetes bacterium V202 QDU09444.1    
 V6x_22780   Planctomycetes bacterium V6 QDU02573.1    
 JD969_06275   Planctomycetota bacterium ZRK32 QQE13063.1    
 JD969_05510   Planctomycetota bacterium ZRK32 QQE12917.1    
 WG950_11660   Polaribacter marinaquae MCCC 1K00696 WYW55182.1    
 RJD25_08210   Pontibacter sp. G13 WNJ20450.1    
 KS4_30670   Poriferisphaera corsica KS4 QDU34990.1    
 KS4_13410   Poriferisphaera corsica KS4 QDU33295.1    
 J5A62_00140   Prevotella histicola F0411 QUB83810.1    
 CRM71_08335   Prevotella jejuni CD3_33 AUI55491.1    
 J5A63_03285   Prevotella jejuni F0106 QUB81479.1    
 J4857_04785   Prevotella jejuni F0697 QUB77325.1    
 HMPREF0659_A6411   Prevotella melaninogenica ATCC 25845 ADK95453.1    
 J5A68_00060   Prevotella melaninogenica F0299 QUB68154.1    
 J5A57_07845   Prevotella melaninogenica F0300 QUB65436.1    
 J5A54_00565   Prevotella melaninogenica F0301 QUB63247.1    
 J4861_11835   Prevotella melaninogenica F0516 QUB61472.1    
 J5A71_01580   Prevotella melaninogenica F0692 QUB58645.1    
 J5A72_07090   Prevotella melaninogenica F0695 QUB56050.1    
 CEP85_00160   Prevotella melaninogenica FDAARGOS_306 ASE16633.1    
 FIU21_11975   Prevotella melaninogenica FDAARGOS_760 QKH89593.1    
 PMEL1_01415   Prevotella melaninogenica GAI 07411 BBA29477.1    
 AXF22_01650   Prevotella scopos JCM 17725 W2052 ANR73274.1    
 J4856_12670   Prevotella scopos JCM 17725 W2052 QUB45554.1    
 RZN69_02000   Puniceicoccus sp. CR14 WOO41843.1    
 Plabr_4762   Rubinisphaera brasiliensis DSM 5305 ADY62333.1    
 L3Q67_03330   Saccharothrix sp. AJ9571 UJW32838.1    
 STSP1_00024   Sedimentisphaera salicampi ST-PulAB-D4 ARN55664.1    
 endo-α-1,2-mannosidase (Sama99; Sama_0297) 3.2.1.130 Shewanella amazonensis SB2B ABL98508.1 A1S2A2  
 K0H79_01525   Shewanella sp. FJAT-52076 QYJ77128.1    
 K0H63_01565   Shewanella zhangzhouensis FJAT-52072 QYK07051.1    
 Solca_2945   Solitalea canadensis DSM 3403 AFD07964.1    
 LVJ94_48785   Sorangiineae bacterium MSr11367 WXB04780.1    
 LZC95_48550   Sorangiineae bacterium MSr12523 WXA94284.1    
 DRN02_015355   Sphingomonas paucimobilis AIMST S2 QBE93223.1    
 SPKIRA_28780   Sphingomonas paucimobilis Kira BCI72048.1    
 JT366_12530   Sphingomonas paucimobilis ZJSH1 QRY94681.1    
 LLW23_08325   Sphingomonas radiodurans S9-5 WBH18083.1    
 STHERM_c15300   Spirochaeta thermophila DSM 6192 ADN02470.1    
 Spith_1563   Spirochaeta thermophila DSM 6578 AEJ61824.1    
 STAUR_3309   Stigmatella aurantiaca DW4/3-1 ADO71101.1    
 GXW83_18205   Streptacidiphilus sp. PB12-B1b QMU77344.1    
 DMT42_31755   Streptomyces actuosus ATCC 25421 AWT47880.1    
 QPM16_09810   Streptomyces anulatus K-31 WIY75953.1    
 OG771_11020   Streptomyces anulatus NBC_01421 WUY04107.1    
 KZO11_09710   Streptomyces anulatus VUW1 QYA93968.1    
 G3H79_04355   Streptomyces aureoverticillatus HN6 QIB42422.1    
 BV401_08475   Streptomyces autolyticus CGMCC0516 AQA10517.1    
 SBI_00635   Streptomyces bingchenggensis BCW-1 ADI03756.1    
 SBI_09400   Streptomyces bingchenggensis BCW-1 ADI12518.1    
 DN051_38445   Streptomyces cadmiisoli ZFG47 AWW41795.1    
 CP983_39790   Streptomyces chartreusis ATCC 14922 QEV73572.1    
 HUT05_42545   Streptomyces chartreusis NA02069 QKZ25171.1    
 R2B67_26435   Streptomyces cyaneofuscatus 89-2-2 WOP11859.1    
 SJX93_09805   Streptomyces cyaneofuscatus NEB1061 WRO09899.1    
 BN159_0556   Streptomyces davaonensis JCM 4913 CCK24935.1    
 M4V62_42105   Streptomyces durmitorensis MS405 UQT61916.1    
 K7395_26290   Streptomyces filamentosus L30 USC49979.1    
 IFE09_09670   Streptomyces fulvissimus DF QQZ53865.1    
 HUT09_09600   Streptomyces fulvissimus NA06532 QKW42807.1    
 WQO_10015   Streptomyces globisporus C-1027 ALU93662.1    
 DIJ69_24220   Streptomyces globisporus TFH56 AWL88610.1    
 SGR_5090   Streptomyces griseus subsp. griseus NBRC 13350 BAG21919.1    
 SHXM_08303   Streptomyces hygroscopicus XM201 AQW54840.1    
 SIRAN8449   Streptomyces iranensis CDR14748.1    
 HA039_31350   Streptomyces liangshanensis QMT-12 QIQ06213.1    
 SMALA_0936   Streptomyces malaysiensis DSM 4137 ATL81171.1
QDL74317.1		    
 SFUL_1990   Streptomyces microflavus DSM 40593 AGK76953.1    
 POD33_31275   Streptomyces moderatus DT446 WCH96384.1    
 BBN63_24330   Streptomyces niveus SCSIO 3406 AQU68854.1    
 SPRI_6730   Streptomyces pristinaespiralis HCCB 10218 ALC25036.1    
 H3L99_03105   Streptomyces pristinaespiralis PR11 QMU12692.1    
 LIV37_43250   Streptomyces rapamycinicus NRRL 5491 UTP35509.1    
 M271_42530   Streptomyces rapamycinicus NRRL 5491 AGP59881.1    
 LJB45_38115   Streptomyces rapamycinicus SRMK07 UTO67555.1    
 I1A49_08165   Streptomyces solisilvae HNM0141 QPI54911.1    
 CGL27_42775   Streptomyces sp. 11-1-2 ASQ98848.1    
 AS97_25290   Streptomyces sp. AgN23 AJZ84839.1    
 RPQ07_33050   Streptomyces sp. AM2-3-1 WNO77385.1    
 RPQ02_36420   Streptomyces sp. AM8-1-1 WNO70042.1    
 JHY03_19200   Streptomyces sp. CA-256286 QTA31784.1    
 HYC88_25715   Streptomyces sp. CB00271 QNQ36732.1    
 CXR04_07415   Streptomyces sp. CMB-StM0423 AUH40093.1    
 AA958_26800   Streptomyces sp. CNQ-509 AKH85244.1    
 KQY30_01030   Streptomyces sp. GMY02 QXE38814.1    
 LUV23_08240   Streptomyces sp. HNM0561 UHH16320.1    
 PGH47_03840   Streptomyces sp. HUAS 31 WCE01976.1    
 RLT58_24890   Streptomyces sp. ITFR-16 WNI24920.1    
 RLT59_27310   Streptomyces sp. ITFR-6 WNI32065.1    
 KJK32_04330   Streptomyces sp. JCM17656 QWA26064.1    
 NEH83_09960   Streptomyces sp. JUS-F4 WKN14513.1    
 STKY70_5504   Streptomyces sp. KY70 CAD5986556.1    
 STKY75_2100   Streptomyces sp. KY75 CAD5945000.1    
 CFP59_07654   Streptomyces sp. M56 AUA15467.1    
 QFW82_38355   Streptomyces sp. NA07423 WHX22475.1    
 OG875_22350   Streptomyces sp. NBC_01498 WTL27066.1    
 LZ559_09760   Streptomyces sp. R527F UIZ12693.1    
 SSPS47_09440 (Xyna1)   Streptomyces sp. S4.7 QHY95346.1    
 H0E86_10095   Streptomyces sp. SCSIO-PteL053 WDT91525.1    
 QFA72_09595   Streptomyces sp. SH5 WGP09920.1    
 PBV52_42655   Streptomyces sp. T12 WDF43026.1    
 TK78_24890   Streptomyces sp. Tue 6075 Tue6075 APS21788.1    
 LEL86_08360   Streptomyces sp. WA6-1-16 UCA49286.1    
 DMB38_28255   Streptomyces sp. WAC 06738 AZM49161.1    
 MWG59_09945   Streptomyces sp. WAC00303 UPT41718.1    
 O7599_08890   Streptomyces sp. WMMC500 WBB62628.1    
 KV381_10060   Streptomyces sp. WY228 QXQ96682.1    
 KME66_24730   Streptomyces sp. YPW6 QWQ43814.1    
 SSPO_083680   Streptomyces sporoclivatus NBRC 100767 BBJ45650.1    
 DEJ48_34345   Streptomyces venezuelae ATCC 14584 QES37822.1    
 Strvi_5963   Streptomyces violaceusniger Tu 4113 AEM85470.1    
 Sros_3784   Streptosporangium roseum DSM 43021 ACZ86705.1    
 PXH66_08650   Synoicihabitans lomoniglobus LMO-M01 WED66918.1    
 TJEJU_3218   Tenacibaculum jejuense KCTC 22618 SNR16870.1    
 MARIT_1314   Tenacibaculum maritimum SFZ81842.1    
 B9C57_05070   Tenacibaculum maritimum TM-KORJJ QCD61957.1    
 PG913_08975   Tenacibaculum pacificus 18-2881-A WBX73015.1    
 THTE_1595   Thermogutta terrifontis R1 ASV74197.1    
 Trebr_0184   Treponema brennaborense DSM 12168 AEE15635.1    
 ORF   uncultured bacterium AIA15982.1    
 Vspart_00170 (PimB)   Vibrio spartinae 3.6 QMV12967.1    
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 I4U23_019551 (fragment)   Adineta vaga UJR32083.1    
 ENSANGG00000018734 (fragment)   Anopheles gambiae str. PEST XP_320623.1
EAA00122.2		    
 ORF (fragment)   Ascaris suum ADY46293.1    
 BEMITA_ LOCUS 4995   Bemisia tabaci CAH0385805.1    
 1626   Blastocystis hominis Singapore isolate B (sub-type 7) (Blahom1)      
 endo-α-mannosidase (protein for IMAGE:7984259) (fragment)   Bos taurus AAI03139.1
AEM43818.1
AFK84025.1
AFK84026.1
AFK84027.1
AFK84028.1		    
 Unknown (protein for MGC:152422)   Bos taurus AAI51267.1    
 MELIAE_ LOCUS 4842   Brassicogethes aeneus CAH0552669.1    
 1439   Cafeteria roenbergensis BVI (Cafroe1)      
 CHIRRI_ LOCUS 11347   Chironomus riparius CAG9808508.1    
 21625   Chlamydomonas reinhardtii CC-4532 v6.1 (ChlreiCC4532_1)      
 12435   Chlamydomonas reinhardtii v5.6 (Chlre5_6)      
 1449   Chlorella sp. A99 (ChloA99_1)      
 134058   Chlorella sp. NC64A (ChlNC64A_1)      
 460   Chromochloris zofingiensis SAG 211-14 (Chrzof1)      
 ORF (fragment)   Coptotermes formosanus AGM32803.1    
 CSTEINMANNI_LOCUS4562702   Coregonus sp. balchen CAB1350915.1    
 CSTEINMANNI_LOCUS1015889   Coregonus sp. balchen CAB1320766.1    
 CSTEINMANNI_LOCUS2529038 (fragment)   Coregonus sp. balchen CAB1333566.1    
 CSTEINMANNI_LOCUS2529039 (fragment)   Coregonus sp. balchen CAB1333567.1    
 CSTEINMANNI_LOCUS2174636   Coregonus sp. balchen CAB1331354.1    
 endomannosidase   Cricetulus griseus ABH07382.1    
 CTOB1V02_LOCUS8236   Cyprideis torosa CAD7230377.1    
 Manea (fragment)   Danio rerio AAH81681.1    
 CH211-30B16.2-001   Danio rerio CAK04938.1    
 DSTB1V02_LOCUS2803   Darwinula stevensoni CAD7242860.1    
 Dbus_chr2Lg2204   Drosophila busckii ALC40119.1    
 DMAD_12099   Drosophila madeirensis RF1 BFF94480.1    
 CG14015   Drosophila melanogaster AAF52260.2
AAL49145.1
NP_608937.1		    
 GA12699   Drosophila pseudoobscura MV2-25 EAL34552.1    
 210275   Emiliania huxleyi (Emihu1)      
 ORF (fragment)   Equus caballus AEQ00826.1    
 195934   Fragilariopsis cylindrus CCMP 1102 (Fracy1)      
 139403   Fragilariopsis cylindrus CCMP 1102 (Fracy1)      
 149315   Fragilariopsis cylindrus CCMP 1102 (Fracy1)      
 178285   Fragilariopsis cylindrus CCMP 1102 (Fracy1)      
 139389   Fragilariopsis cylindrus CCMP 1102 (Fracy1)      
 LOC421807   Gallus gallus XP_419831.1    
 LOC419611   Gallus gallus XP_417758.1    
 104143   Guillardia theta CCMP2712 (Guith1)      
 117863   Guillardia theta CCMP2712 (Guith1)      
 110280   Guillardia theta CCMP2712 (Guith1)      
 149606   Guillardia theta CCMP2712 (Guith1)      
 136026   Guillardia theta CCMP2712 (Guith1)      
 132254   Helobdella robusta (Helro1)      
 HERILL_LOCUS3385   Hermetia illucens CAD7080219.1    
 HAMR1_LOCUS8453   Heterobilharzia americana CAH8592305.1    
 HAMR2_LOCUS7684   Heterobilharzia americana CAH8621261.1    
 glycoprotein endo-α-1,2-mannosidase (ManeA) 3.2.1.130 Homo sapiens CAE12165.1
AAI46672.1
AAI50200.1
AAL07306.1
AAL07307.1
AAQ75077.1
ACH33940.1
BAB14298.1
BAF84629.1
CAD97640.1
CAE45927.1
CAH33902.1
CAI17346.1
CAI17347.1
NP_078917.2		 A6H8M6
Q5SRI9
Q8WWX4		 6ZDC[A]
6ZDF[A,B,C]
6ZDK[AAA]
6ZDL[AAA]
6ZFA[AAA]
6ZFN[AAA]
6ZFQ[AAA]
6ZJ1[AAA]
6ZJ5[AAA]
 ManeAL   Homo sapiens CAH70081.1
AAH09952.2
AAH31903.1
AAH63587.1
AAH77730.1
ABE14780.1
BAB71068.1
BAG62934.1
CAH70082.1
NP_689709.1		    
 489070   Hyaloraphidium curvatum SAG235-1 v1.0 (Hyacur1)      
 ORF (ManeA)   Ictalurus punctatus AHH39207.1    
 LSAA_2888   Lepeophtheirus salmonis IoA-00 CAF2810124.1
CAB4057070.1		    
 glycoprotein endo-α-1,2-mannosidase (ManeA)   Macaca mulatta AFE66476.1
AFH27753.1		    
 ORF (fragment)   Macaca mulatta AFE70497.1    
 Manea   Mus musculus AAH67076.1
BAC26805.1
CAM23963.1
NP_766453.2		    
 Gm50 (ManeaL)   Mus musculus AAH65047.1
BAE23227.1
CAM16102.1		    
 ORF   Mustela putorius furo AES01516.1    
 ORF (fragment)   Mustela putorius furo AES01517.1    
 ORF (fragment)   Mustela putorius furo AES01518.1    
 MAR_017306   Mya arenaria isolate MELC-2E11 WAR07348.1    
 MAR_017237 (fragment)   Mya arenaria isolate MELC-2E11 WAR07279.1    
 KARACHINF001_ LOCUS 11021   Naegleria fowleri CAG4718666.1    
 62591   Naegleria gruberi (Naegr1)      
 1963   Nannochloropsis gaditana B-31 (Nangad1)      
 NTJ_14237   Nesidiocoris tenuis Japan BET01421.1    
 NEZAVI_ LOCUS 11176 (fragment)   Nezara viridula CAH1402331.1    
 4160   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 21199   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 29081   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 23007   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 6323   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 4161   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 23005   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 36816   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 35226   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 4620   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 24806   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 21202   Nitzschia hildebrandi GAI-293 v2.0 (Nithil2)      
 OCTVUL_1B013658   Octopus vulgaris CAI9736008.1    
 OKIOD_ LOCUS 7363   Oikopleura dioica CAG5098592.1    
 LOC472074   Pan troglodytes XP_527453.1    
 PECUL_23A056098 (fragment)   Pelobates cultripes CAH2222080.1    
 PECUL_23A016286 (fragment)   Pelobates cultripes CAH2222081.1    
 PECUL_23A046257   Pelobates cultripes CAH2252625.1    
 47966   Phaeodactylum tricornutum CCAP 1055/1 v2.0 (Phatr2)      
 glycoprotein endo-α-1,2-mannosidase (ManeA)   Phallusia mammillata CAB3263610.1    
 MPIPNATIZW_LOCUS15067   Pipistrellus nathusii CAK6446761.1    
 MPIPNATIZW_LOCUS9271   Pipistrellus nathusii CAK6440965.1    
 PODLI_1B009751   Podarcis lilfordi CAI5781858.1    
 PODLI_1B018504   Podarcis lilfordi CAI5769846.1    
 DKFZp469G135   Pongo abelii CAH90264.1    
 2487   Prasinoderma coloniale CCMP1413 (Praco1_1)      
 MRATA1EN1_LOCUS13269   Rangifer tarandus platyrhyncus CAI9164307.1    
 MRATA1EN1_LOCUS1408   Rangifer tarandus platyrhyncus CAI9152446.1    
 endo-α-1,2-mannosidase (Enman) 3.2.1.130 Rattus norvegicus AAT44962.1
AAB86925.1
NP_542963.1
XP_346734.1		 Q5GF25  
 LOC366466 (fragment)   Rattus norvegicus XP_345581.1    
 SBOV2_LOCUS6853   Schistosoma bovis CAH8612565.1    
 SBOV1_LOCUS6773   Schistosoma bovis CAH8618154.1    
 SCUR2_LOCUS6759   Schistosoma curassoni CAH8614746.1    
 SGUI1_LOCUS6954   Schistosoma guineensis CAH8609911.1    
 SHAE1_LOCUS7059   Schistosoma haematobium CAH8625897.1    
 SHAE2_LOCUS7221   Schistosoma haematobium CAH8633138.1    
 SINT1_LOCUS6729   Schistosoma intercalatum CAH8597168.1    
 SINT2_LOCUS6774   Schistosoma intercalatum CAH8598514.1    
 Smp_016880   Schistosoma mansoni Puerto Rico CAZ29389.1
CCD80792.1		    
 SMRG1_LOCUS7037   Schistosoma margrebowiei CAH8615660.1    
 SMTH1_LOCUS7649   Schistosoma mattheei CAH8587377.1    
 SRDH1_LOCUS6565   Schistosoma rodhaini CAH8631075.1    
 SRDH2_LOCUS7097   Schistosoma rodhaini CAH8631905.1    
 SSPN1_LOCUS6617   Schistosoma spindale CAI2732593.1    
 STRK1_LOCUS6769 (fragment)   Schistosoma turkestanicum CAH8547774.1    
 STRK1_LOCUS6774 (fragment)   Schistosoma turkestanicum CAH8547876.1    
 SMAX5B_012027   Scophthalmus maximus AWO96264.1    
 SMAX5B_016224   Scophthalmus maximus AWP04785.1    
 SRAE_2000015400   Strongyloides ratti ED321 Heterogonic CEF65474.1    
 12861   Symbiodinium microadriaticum CCMP2467 (Symmic1)      
 6903   Symbiodinium microadriaticum CCMP2467 (Symmic1)      
 OEZ85_012169   Tetradesmus obliquus DOE0152z WIA12093.1    
 OEZ86_003077   Tetradesmus obliquus DOE0152z WIA32229.1    
 GSTEN:00031982:G:001   Tetraodon nigroviridis CAG10373.1    
 101547   Thalassiosira oceanica CCMP1005 (Thaoce1)      
 TDIB3V08_LOCUS3194   Timema douglasi CAD7196868.1    
 TSIB3V08_LOCUS11695   Timema shepardi CAD7267690.1    
 TREG1_LOCUS9893   Trichobilharzia regenti CAH8866053.1    
 TSZD1_LOCUS10316   Trichobilharzia szidati CAH8865751.1    
 MOV77_017241   Trichomonas stableri BTPI-3 WGY94105.1    
 MOV77_020930   Trichomonas stableri BTPI-3 WGY97953.1    
 MOV77_021163   Trichomonas stableri BTPI-3 WGY98182.1    
 MOV77_012029   Trichomonas stableri BTPI-3 WGY91487.1    
 MOV77_010851   Trichomonas stableri BTPI-3 WGY88537.1    
 MOV77_010575   Trichomonas stableri BTPI-3 WGY88272.1    
 MOV77_029431   Trichomonas stableri BTPI-3 WGZ05648.1    
 MOV77_031094   Trichomonas stableri BTPI-3 WGZ07107.1    
 9931   Volvox carteri v2.1 (Volca2_1)      
 Maneα-prov   Xenopus laevis AAH77304.1    
 Unknown (protein for MGC:121847)   Xenopus tropicalis AAI35933.1
AAI52045.1		    
 XNOV1_A005656   Xyrichtys novacula CAJ1083541.1    
 XNOV1_A000013   Xyrichtys novacula CAJ1073347.1    
 XNOV1_A025130   Xyrichtys novacula CAJ1062703.1    
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BN138_675   termite gut metagenome CCO21487.1    
 BN138_915   termite gut metagenome CCO21727.1    
 BN138_935   termite gut metagenome CCO21747.1    
 BN138_955   termite gut metagenome CCO21767.1    
 BN138_1026   termite gut metagenome CCO21838.1    
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