Glycoside Hydrolase Family 98

Activities in Familyblood-group endo-β-1,4-galactosidase (EC 3.2.1.102); blood group A- and B-cleaving endo-β-1,4-galactosidase (EC 3.2.1.-); endo-β-1,4-xylanase (EC 3.2.1.8);
Mechanism inverting
3D Structure Status( α / β ) 8 barrel
Catalytic Nucleophile/BaseAsp+Glu diad
Catalytic Proton DonorGlu
NoteCreated after Anderson et al. (J. Biol. Chem. 2005 280: 7720-7728; PMID:15618227)
External resourcesCAZypedia;
Statistics GenBank accession (395); Uniprot accession (29); PDB accession (16); 3D entries (2); cryst (0)
| 1 | 2 | 3 | 4 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SAMEA3714019_02082   Streptococcus pneumoniae 2245STDY6178854 VGM83558.1    
 SAMEA3714262_02009   Streptococcus pneumoniae 2245STDY6179186 VFI49873.1    
 C4N11_11440   Streptococcus pneumoniae 335 AVD76032.1    
 EZ481_05825   Streptococcus pneumoniae 521 QBK28222.1    
 SP670_2305   Streptococcus pneumoniae 670-6B ADM92355.1 E0TRE6  
 HKM25_2255   Streptococcus pneumoniae 6A-10 QJS37903.1    
 SP70585_2286   Streptococcus pneumoniae 70585 ACO16885.1 C1CB04  
 T308_10350   Streptococcus pneumoniae A026 AGZ48648.1    
 A66_01966   Streptococcus pneumoniae A66 CRI62677.1    
 SPAP_2208   Streptococcus pneumoniae AP200 ADM85739.1 E0SZ19  
 ASP0581_20850   Streptococcus pneumoniae ASP0581 BBG82607.1    
 SPAT_2049 (EabC)   Streptococcus pneumoniae ATCC 49619 BBG40052.1    
 SPN23F21910   Streptococcus pneumoniae ATCC 700669 CAR69924.1 B8ZPZ7  
 GJE16_10275   Streptococcus pneumoniae AUSMDU00010538 QGK04730.1    
 SPCG_2128   Streptococcus pneumoniae CGSP14 ACB91380.1 B2INH9  
 DA395_10990   Streptococcus pneumoniae CP2215 AVV92269.1    
 SPND141_02109   Streptococcus pneumoniae D141 AOG59126.1    
 SPND219_02199   Streptococcus pneumoniae D219 ANO37934.1    
 SPD_1987   Streptococcus pneumoniae D39 ABJ53832.1 Q04I15  
 SPV_1987 (FucL)   Streptococcus pneumoniae D39V AVN86989.1    
 C3Y86_10535   Streptococcus pneumoniae EF3030 AXK92325.1
QBF69851.1
   
 SPG_2101 (fragment)   Streptococcus pneumoniae G54 ACF55203.1 B5E3Q1  
 SPG_2100 (fragment)   Streptococcus pneumoniae G54 ACF55999.1 B5E3Q0  
 HMPREF1038_02169   Streptococcus pneumoniae gamPNI0373 AFS44133.1    
 BWQ98_10590   Streptococcus pneumoniae HKU1-14 AZT88159.1    
 SPOH_2004 (EabC)   Streptococcus pneumoniae HU-OH BBG37983.1    
 SPNHU15_02194   Streptococcus pneumoniae Hu15 ARD37938.1    
 SPNHU17_02220   Streptococcus pneumoniae Hu17 ARD35744.1    
 SPH_2353   Streptococcus pneumoniae Hungary19A-6 ACA36133.1 B1I9W9  
 INV104_18630   Streptococcus pneumoniae INV104 CBW37544.1 E1XNH7  
 SPNINV200_19700   Streptococcus pneumoniae INV200 CBW35603.1 E1XMI5  
 SPJ_2185   Streptococcus pneumoniae JJA ACO20088.1 C1CHF8  
 KK0381_16310   Streptococcus pneumoniae KK0381 BAX31760.1    
 KK0981_41780   Streptococcus pneumoniae KK0981 BAW85613.1    
 KK1157_16570   Streptococcus pneumoniae KK1157 BAX33976.1    
 MDRSPN_01970   Streptococcus pneumoniae MDRSPN001 BBA60114.1    
 NCTC11902_02080   Streptococcus pneumoniae NCTC11902 SQG99630.1    
 NCTC12977_01611 (Fucolectin-reL)   Streptococcus pneumoniae NCTC12977 VEE30313.1    
 NCTC13276_02011   Streptococcus pneumoniae NCTC13276 SQG35203.1    
 ERS445053_00606 (Fucolectin-reL)   Streptococcus pneumoniae NCTC7465 COT09460.1    
 NCTC7466_02019   Streptococcus pneumoniae NCTC7466 SQG02988.1    
 SPNU_2118 (EabC)   Streptococcus pneumoniae NU83127 BBG35955.1    
 SPNOXC_19050   Streptococcus pneumoniae OXC141 CBW33557.1 E1XDJ0  
 SPP_2210   Streptococcus pneumoniae P1031 ACO21560.1 C1CND1  
 HA248_10710   Streptococcus pneumoniae PZ900701590 QIQ00718.1    
 Spr1965   Streptococcus pneumoniae R6 AAL00767.1
NP_359556.1
Q8CY62  
 E5Q10_10480   Streptococcus pneumoniae R6CIB17 QEL29241.1    
 Sequence 204 from patent US 6929930 (partial)   Streptococcus pneumoniae SP042 ABA33101.1    
 endo-β-1,4-galactosidase (CGSSp3BS71_10403;Sp3GH98;EABase) (blood-group A/B-antigen-specific) 3.2.1.102 Streptococcus pneumoniae SP3-BS71 EDK74349.1 A5LBQ0 2WMI[A,B]
2WMJ[A,B]
2WMK[A,B]
4D6C[A]
4D6D[A]
4D6E[A]
4D6F[A]
4D6G[A]
4D6H[A]
4D6I[A]
4D6J[A]
4D71[A]
4D72[A]
 BMJ42_02235   Streptococcus pneumoniae SP49 APJ31457.1    
 BOC71_02049   Streptococcus pneumoniae SP61 APJ33476.1    
 BOC72_02051   Streptococcus pneumoniae SP64 APJ35501.1    
 C1H54_10790   Streptococcus pneumoniae SPN XDR SMC1710-32 AXJ89288.1    
 SPN034156_09840 (fragment)   Streptococcus pneumoniae SPN034156 SNP034156 CCP36653.1    
 SPN034183_19080   Streptococcus pneumoniae SPN034183 SNP034183 CCP33618.1    
 SPN994038_18970   Streptococcus pneumoniae SPN994038 SNP994038 CCP31633.1    
 SPN994039_18980   Streptococcus pneumoniae SPN994039 SNP994039 CCP35592.1    
 SPNA45_02012   Streptococcus pneumoniae SPNA45 CCM09295.1    
 MYY_03670   Streptococcus pneumoniae ST556 AKU19989.1    
 SPT_2172 (fragment)   Streptococcus pneumoniae Taiwan19F-14 ACO22731.1 C1CU78  
 HMPREF0837_10162   Streptococcus pneumoniae TCH8431/19A ADI68390.1 D6ZNV6  
 endo-β-1,4-galactosidase (SP_2159;SP2159;Sp4GH98) (LewisY-specific) 3.2.1.102 Streptococcus pneumoniae TIGR4 AAK76213.1
AAY71778.1
NP_346573.1
Q97N96 2WMF[A]
2WMG[A]
2WMH[A]
 CXP32_11160   Streptococcus pneumoniae Xen35 AUF85833.1    
 YS19-GM000005   Streptococcus suis QID25761.1    
 HAS68_10490   Streptococcus suis 05HAS68 AHF59608.1    
 ID09_05105   Streptococcus suis 6407 AIG43443.1    
 AN924_20190   Streptococcus suis 90-1330 AMU80434.1    
 SSUA7_0850   Streptococcus suis A7 AER44175.1    
 CR542_05280   Streptococcus suis HA0609 AUW25933.1    
 CWM22_06250   Streptococcus suis HN136 AUC91522.1    
 DK877_06700   Streptococcus suis ISU2414 QLL53599.1    
 DK878_05210   Streptococcus suis ISU2660 QLL55427.1    
 A7J09_06365   Streptococcus suis ISU2812 ASW51765.1    
 AA105_05475   Streptococcus suis NSUI002 ALA28705.1    
 DP111_04795   Streptococcus suis SH1510 AXI65391.1    
 T15_1056   Streptococcus suis T15 AGZ23149.1    
 fucolectin-related protein   Streptococcus suis ZJ20091101 ANJ64027.1    
 XALc_2784   Xanthomonas albilineans GPE PC73 CBA17261.1    
 XaFJ1_GM002800   Xanthomonas albilineans Xa-FJ1 QHQ29512.1    
 XACM_0813 (fragment)   Xanthomonas axonopodis pv. citrumelo F1 AEO41116.1    
 Xcom_17845   Xanthomonas axonopodis pv. commiphoreae LMG26789 AYO96613.1    
 XAV_17200   Xanthomonas axonopodis pv. vasculorum NCPPB 796 QKD87752.1    
 XAC29_04165   Xanthomonas axonopodis Xac29-1 AGH76359.1    
 XCV0869   Xanthomonas campestris pv. vesicatoria str. 85-10 CAJ22500.1
AOY68479.1
Q3BXB3  
 AC028_10285 (fragment)   Xanthomonas citri pv. aurantifolii 1566 AMV07146.1    
 TP37_17680 (fragment)   Xanthomonas citri pv. aurantifolii FDC 1559 AMU99706.1    
 TP45_03610 (fragment)   Xanthomonas citri pv. aurantifolii FDC 1561 ARE55522.1    
 CLM98_04860   Xanthomonas citri pv. citri 03-1638-1-1 AUZ49975.1    
 J152_00937   Xanthomonas citri pv. citri 5208 AJZ38629.1    
 J165_03740   Xanthomonas citri pv. citri AW13 AJZ45829.1    
 J166_03744   Xanthomonas citri pv. citri AW14 AJZ50448.1    
 J167_03745   Xanthomonas citri pv. citri AW15 AJZ55069.1    
 J168_03741   Xanthomonas citri pv. citri AW16 AJZ67860.1    
 J170_00933   Xanthomonas citri pv. citri BL18 AJZ34160.1    
 H8Z73_04135   Xanthomonas citri pv. citri DAR72029 QRD65465.1    
 H8Z71_17555   Xanthomonas citri pv. citri DAR73886 QRD73122.1    
 H8Z72_04145   Xanthomonas citri pv. citri DAR73889 QRD70061.1    
 H8Z74_04160   Xanthomonas citri pv. citri DAR73909 QRD60967.1    
 H8Z75_10195   Xanthomonas citri pv. citri DAR73910 QRD57713.1    
 H8Z70_17665   Xanthomonas citri pv. citri DAR84832 QRD77518.1    
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