Glycoside Hydrolase Family 97

Activities in Familyglucoamylase (EC 3.2.1.3); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22)
Mechanism inverting and retain
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu for inverting members; Asp for retaining members
Catalytic Proton DonorGlu
NoteCreated based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178)
External resourcesCAZypedia;
Statistics GenBank accession (1052); Uniprot accession (166); PDB accession (12); 3D entries (3); cryst (0)
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 α-glucosidase precursor (Agls6)   insect gut metagenome ARK08559.1    
 α-galactosidase precursor (Agas2)   insect gut metagenome ARK08558.1    
 BN138_165   termite gut metagenome CCO20977.1    
 BN138_677   termite gut metagenome CCO21489.1    
 BN138_916   termite gut metagenome CCO21728.1    
 BN138_934   termite gut metagenome CCO21746.1    
 BN138_956   termite gut metagenome CCO21768.1    
 BN138_1027   termite gut metagenome CCO21839.1    
 BN138_145 (fragment)   termite gut metagenome CCO20957.1    
 BN138_248 (fragment)   termite gut metagenome CCO21060.1    
 BN138_1061 (fragment)   termite gut metagenome CCO21873.1    
 ORF   uncultured organism ADD61400.1
ADD62005.1
D9ZDJ6  
 ORF   uncultured organism ADD61494.1 D9ZDU0  
 ORF   uncultured organism ADD61864.1
AIA90682.1
D9ZEW0  
 c11_3   uncultured organism AGU09968.1    
 ORF   uncultured organism AGU10215.1    
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