Glycoside Hydrolase Family 97

Activities in Familyglucoamylase (EC 3.2.1.3); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22)
Mechanism inverting and retain
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu for inverting members; Asp for retaining members
Catalytic Proton DonorGlu
NoteCreated based on a paper by Hughes et al. (2003) Oral Microbiol Immunol. 18:309-312 (PMID: 12930523); *Mechanistic and structural elucidation by Gloster et al. (2008) Chem. Biol., Oct 8 (PMID:18848471); the inverting a-glucosidases (EC 3.2.1.20) could be renamed glucoamylases (EC 3.2.1.3 according to Kitamura et al. (2008) J. Biol. Chem., Nov 3 (PMID:18981178)
External resourcesCAZypedia;
Statistics GenBank accession (1008); Uniprot accession (166); PDB accession (12); 3D entries (3); cryst (0)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 HacjB3_16901   Halalkalicoccus jeotgali B3 ADJ16730.1 D8JBS7  
 HacjB3_05815   Halalkalicoccus jeotgali B3 ADJ14554.1 D8JA32  
 HacjB3_05815   Halalkalicoccus jeotgali B3 ADJ14554.1 D8JA32  
 HacjB3_16781 (possible fragment)   Halalkalicoccus jeotgali B3 ADJ16706.1 D8JBQ3  
 HAH_2960 (Agla2)   Haloarcula hispanica ATCC 33960 CGMCC 1.2049 AEM58534.1    
 HAH_2960 (Agla2)   Haloarcula hispanica ATCC 33960 CGMCC 1.2049 AEM58534.1    
 HISP_15050   Haloarcula hispanica N601 AHB67258.1    
 HISP_15050   Haloarcula hispanica N601 AHB67258.1    
 rrnAC0205 (AglA2)   Haloarcula marismortui ATCC 43049 AAV45265.1 Q5V5D6  
 rrnAC0205 (AglA2)   Haloarcula marismortui ATCC 43049 AAV45265.1 Q5V5D6  
 SG26_07165   Haloarcula sp. CBA1115 AJF25521.1    
 SG26_07165   Haloarcula sp. CBA1115 AJF25521.1    
 HFX_6123 (Amy7)   Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK21248.1    
 HFX_6123 (Amy7)   Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK21248.1    
 Halxa_3685   Halopiger xanaduensis SH-6 AEH38293.1    
 Halxa_3685   Halopiger xanaduensis SH-6 AEH38293.1    
 HTIA_1045   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33183.1    
 Huta_1153   Halorhabdus utahensis DSM 12940 ACV11329.1 C7NML6  
 HALLA_03285   Halostagnicola larsenii XH-48 AHG01424.1    
 Htur_3876   Haloterrigena turkmenica DSM 5511 ADB62734.1 D2S037  
 Htur_1460   Haloterrigena turkmenica DSM 5511 ADB60346.1 D2RQL5  
 Htur_1460   Haloterrigena turkmenica DSM 5511 ADB60346.1 D2RQL5  
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