Glycoside Hydrolase Family 95

Activities in Familyα-L-fucosidase (EC 3.2.1.51); α-1,2-L-fucosidase (EC 3.2.1.63); α-L-galactosidase (EC 3.2.1.-)
Mechanism Inverting
3D Structure Status( α / α ) 6 barrel
Catalytic Nucleophile/BaseAsn activated by Asp
Catalytic Proton DonorGlu
NoteCreated based on a paper by Katayama, Sakuma, Kimura, Makimura, Hiratake, Sakata, Yamanoi, Kumagai, and Yamamoto (J. Bacteriol. 2004 Aug;186(15):4885-4893)
External resourcesCAZypedia;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4255); Uniprot accession (14); PDB accession (7); 3D entries (4); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 [xyloglucan] α-1,2-L-fucosidase (BfGH95; HMPREF9446_01800) 3.2.1.63 pubmed
Bacteroides fluxus YIT 12057 EGF57198.1    
 α-L-galactosidase (BACOVA_03438;Bovatus_03734) 3.2.1.- pubmed
Bacteroides ovatus ATCC 8483 ALJ48339.1
EDO10805.1
A7M011 4UFC[A,B]
 α-L-galactosidase (cleaves L-Galp-α-1,2-D-GlcpA; BT1010) 3.2.1.- pubmed
Bacteroides thetaiotaomicron VPI-5482 AAO76117.1
NP_809923.1
Q8A907  
 [xyloglucan] α-1,2-L-fucosidase (BuGH95; BACUNI_00326) 3.2.1.63 pubmed
Bacteroides uniformis ATCC 8492 EDO56039.1    
 α-1,2-L-fucosidase (AfcA;AfuA;BbAfcA) 3.2.1.63 pubmed
Bifidobacterium bifidum JCM 1254 AAQ72464.1 Q6JV24 2EAB[A,B]
2EAC[A,B]
2EAD[A,B]
2EAE[A]
 α-1,2-L-fucosidase (Blon_2335) 3.2.1.63 pubmed
Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ53393.1 B7GNN7  
 α-L-fucosidase 95A (CjAfc95A;CJA_2710) (Afc95A) 3.2.1.63 pubmed
Cellvibrio japonicus Ueda107 ACE83895.1 B3PBE3  
 α-1,2-L-fucosidase (Afc3;CPF_2129) 3.2.1.63 pubmed
Clostridium perfringens ATCC 13124 ABG82552.1 A0A0H2YQB3
Q0TP83
 
 [xyloglucan] α-1,2-L-fucosidase (DgGH95; HMPREF9455_00301) 3.2.1.63 pubmed
Dysgonomonas gadei ATCC BAA-286 EGJ99268.1    
 α-1,2-fucosidase (RiFuc95; EEG94251.1+EEG94250.1+EEG94249.1) 3.2.1.63 pubmed
Roseburia inulinivorans DSM 16841 EEG94249.1
EEG94250.1
C0FT20  
 α-L-fucosidase (RUMGNA_00842; RGna_14480) 3.2.1.51
3.2.1.63
pubmed
pubmed
[Ruminococcus] gnavus ATCC 29149 QHB24557.1    
 α-1,2-L-fucosidase (SpGH95;SP_1654) 3.2.1.63 pubmed
Streptococcus pneumoniae TIGR4 AAK75733.1
NP_346093.1
A0A0H2UR14  
 α-1,2-L-fucosidase (XAC1774) 3.2.1.63 doi
Xanthomonas citri pv. citri str. 306 AAM36638.1
NP_642102.1
Q8PLM1 B[nd]
7KMQ[A]
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 α-1,2-L-fucosidase (Axy8;AXY8;At4g34260) (Fuc95A) 3.2.1.63 pubmed
Arabidopsis thaliana CAB36703.1
AAM78086.1
AAO11638.1
AEE86349.1
CAB80143.1
NP_195152.2
Q8L7W8  
 α-1,2-L-fucosidase (AN8149.2) 3.2.1.63 pubmed
Aspergillus nidulans FGSC A4 EAA59171.1
ABF50892.1
C8V6V7
Q5AU81
 
 α-1,2-L-fucosidase (EBM II;LlFuc) 3.2.1.63 pubmed
Lilium longiflorum BAF85832.1 A8J657  
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