Glycoside Hydrolase Family 94

Activities in Familycellobiose phosphorylase (EC 2.4.1.20); laminaribiose phosphorylase (EC 2.4.1.31); cellodextrin phosphorylase (EC 2.4.1.49); chitobiose phosphorylase (EC 2.4.1.-); cyclic β-1,2-glucan synthase (EC 2.4.1.-); cellobionic acid phosphorylase (EC 2.4.1.321); β-1,2-oligoglucan phosphorylase (EC 2.4.1.-)
Mechanism Inverting
3D Structure Status( α / α ) 6
Catalytic Nucleophile/Basephosphate
Catalytic Proton DonorAsp
NoteFormerly known as glycosyltransferase family GT36; Assigned to a GH family following a paper by Hidaka, Honda, Kitaoka, Nirasawa, Hayashi, Wakagi, Shoun and Fushinobu (Structure (Camb). 2004 Jun;12(6):937-947) (PMID: 15274915) that revealed the evolutionary, structural and mechanistic relationship of these phosphorylases with glycoside hydrolases of clan GH-L.
External resourcesCAZypedia;
Statistics GenBank accession (1859); Uniprot accession (337); PDB accession (28); 3D entries (7); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF (fragment)   Leptosphaeria maculans JN3 v23.1.3 CBX91997.1 E5R527  
 MG06545.4   Magnaporthe oryzae 70-15 EAA56574.1
XP_370030.1
G4N6K9  
 cellobionic acid phosphorylase (CelAP;NdvB;NCU09425) 2.4.1.321 Neurospora crassa OR74A EAA28929.1
XP_332117.1
Q7S0S2  
 Pa_5_12590   Podospora anserina S mat+ CAP62145.1
CDP29217.1
B2AFC7  
 MYCTH_2308030   Thermothelomyces thermophila ATCC 42464 AEO59604.1    
 THITE_2117883   Thielavia terrestris NRRL 8126 AEO68382.1    
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