Glycoside Hydrolase Family 94

Activities in Familycellobiose phosphorylase (EC 2.4.1.20); laminaribiose phosphorylase (EC 2.4.1.31); cellodextrin phosphorylase (EC 2.4.1.49); chitobiose phosphorylase (EC 2.4.1.-); cyclic β-1,2-glucan synthase (EC 2.4.1.-); cellobionic acid phosphorylase (EC 2.4.1.321); β-1,2-oligoglucan phosphorylase (EC 2.4.1.-)
Mechanism Inverting
3D Structure Status( α / α ) 6
Catalytic Nucleophile/Basephosphate
Catalytic Proton DonorAsp
NoteFormerly known as glycosyltransferase family GT36; Assigned to a GH family following a paper by Hidaka, Honda, Kitaoka, Nirasawa, Hayashi, Wakagi, Shoun and Fushinobu (Structure (Camb). 2004 Jun;12(6):937-947) (PMID: 15274915) that revealed the evolutionary, structural and mechanistic relationship of these phosphorylases with glycoside hydrolases of clan GH-L.
External resourcesCAZypedia;
Statistics GenBank accession (1859); Uniprot accession (337); PDB accession (28); 3D entries (7); cryst (0)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 HTIA_1242   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33376.1    
 HTIA_1241   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33375.1    
 HTIA_0903   Halorhabdus tiamatea SARL4B type strain: SARL4B CCQ33042.1    
 Huta_1364   Halorhabdus utahensis DSM 12940 ACV11540.1 C7NNE0  
 Huta_1363   Halorhabdus utahensis DSM 12940 ACV11539.1 C7NND9  
 Igag_1810   Ignisphaera aggregans DSM 17230 ADM28607.1 E0SSM2  
 MCON_0069   Methanosaeta concilii GP6 AEB66984.1    
 Mpal_0623   Methanosphaerula palustris E1-9c ACL15994.1 B8GFE6  
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