Glycoside Hydrolase Family 92

Activities in Familymannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide α-1,3-mannosidase (EC 3.2.1.-); mannosyl-oligosaccharide α-1,6-mannosidase (EC 3.2.1.-); α-mannosidase (EC 3.2.1.24); α-1,2-mannosidase (EC 3.2.1.-); α-1,3-mannosidase (EC 3.2.1.-); α-1,4-mannosidase (EC 3.2.1.-); mannosyl-1-phosphodiester α-1,P-mannosidase (EC 3.2.1.-)
Mechanism Inverting
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteAsp
External resourcesCAZypedia; MEGAZYME;
Statistics GenBank accession (2754); Uniprot accession (397); PDB accession (11); 3D entries (4); cryst (0)
All (2652) Bacteria (2507) Eukaryota (141) unclassified (4) Structure (4) Characterized (29)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 mannosyl-oligosaccharide α-1,2-mannosidase (BT3990) 3.2.1.113 Bacteroides thetaiotaomicron VPI-5482 AAO79095.1
NP_812901.1
Q8A0N1
2WVX[A,B,C,D] 1.90
2WVZ[A,B,C,D] <carb_like_KIF>
2.40
2WW0[A,B,C,D,E,F,G,H] <carb_like_SWA>
2.80
2WW1[A,B,C,D] α-D-Manp-(1-2)-α-D-Manp2S-(1-1)-methyl
2.25
2WW3[A,B,C,D,E,F] α-D-Manp-(1-2)-α-D-Manp2S-(1-1)-methyl
2.10
2WZS[A,B,C,D,E,F,G,H] <carb_like_MVL>
2.25
 mannosyl-oligosaccharide α-1,2-mannosidase (BT2199) 3.2.1.113 Bacteroides thetaiotaomicron VPI-5482 AAO77306.1
NP_811112.1
Q8A5N9
2WVY[A,B,C] 2.26
2WW2[A,B,C] <carb_like_SWA>
1.90
 [N-glycan] (Man-1-Pi-6-Man-specific) uncapping α-mannosidase (CcGH92_5;CcMan5) 3.2.1.- Cellulosimicrobium cellulans AFK83609.1  
2XSG[A,B] 2.00
4AQ0[A,B] <carb_like_DMJ>
2.09
 mannosyl-oligosaccharide α-1,2-mannosidase (SpGH92;SP_2145;SP2145) 3.2.1.113 Streptococcus pneumoniae TIGR4 AAK76202.1
NP_346562.1
Q97NA7
5SWI[A,B,C,D] β-D-Manp
2.15
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