Glycoside Hydrolase Family 92

Known Activitiesmannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide α-1,3-mannosidase (EC 3.2.1.-); mannosyl-oligosaccharide α-1,6-mannosidase (EC 3.2.1.-); α-mannosidase (EC 3.2.1.24); α-1,2-mannosidase (EC 3.2.1.-); α-1,3-mannosidase (EC 3.2.1.-); α-1,4-mannosidase (EC 3.2.1.-); mannosyl-1-phosphodiester α-1,P-mannosidase (EC 3.2.1.-)
Mechanism Inverting
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorGlu
NoteAsp
External resourcesCAZypedia;
Statistics GenBank accession (1162); Uniprot accession (398); PDB accession (10); 3D entries (3); cryst (0)
All (1061) Bacteria (966) Eukaryota (84) unclassified (11) Structure (3 ) Characterized (22)
Bacteria
Protein Name EC#Organism
PDB/3D Carbohydrate LigandsResolution (Å)
 mannosyl-oligosaccharide α-1,2-mannosidase (BT3990) 3.2.1.113 Bacteroides thetaiotaomicron VPI-5482
2WVX[A,B,C,D] 1.90
2WVZ[A,B,C,D] <carb_like_KIF>
2.40
2WW0[A,B,C,D,E,F,G,H] <carb_like_SWA>
2.80
2WW1[A,B,C,D] α-D-Manp-(1-2)-α-D-Manp2S-(1-1)-methyl
2.25
2WW3[A,B,C,D,E,F] α-D-Manp-(1-2)-α-D-Manp2S-(1-1)-methyl
2.10
2WZS[A,B,C,D,E,F,G,H] <carb_like_MVL>
2.25
 mannosyl-oligosaccharide α-1,2-mannosidase (BT2199) 3.2.1.113 Bacteroides thetaiotaomicron VPI-5482
2WVY[A,B,C] 2.26
2WW2[A,B,C] <carb_like_SWA>
1.90
 [N-glycan] (Man-1-Pi-6-Man-specific) uncapping α-mannosidase (CcGH92_5;CcMan5) 3.2.1.- Cellulosimicrobium cellulans
2XSG[A,B] 2.00
4AQ0[A,B] <carb_like_DMJ>
2.09
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