Known Activities	mannosyl-oligosaccharide α-1,2-mannosidase (EC 3.2.1.113); mannosyl-oligosaccharide α-1,3-mannosidase (EC 3.2.1.-); mannosyl-oligosaccharide α-1,6-mannosidase (EC 3.2.1.-); α-mannosidase (EC 3.2.1.24); α-1,2-mannosidase (EC 3.2.1.-); α-1,3-mannosidase (EC 3.2.1.-); α-1,4-mannosidase (EC 3.2.1.-); mannosyl-1-phosphodiester α-1,P-mannosidase (EC 3.2.1.-)
Mechanism	Inverting
Catalytic Nucleophile/Base	Asp
Catalytic Proton Donor	Glu
Note	Asp
External resources	CAZypedia; MEGAZYME;
Statistics	GenBank accession (2081); Uniprot accession (397); PDB accession (10); 3D entries (3); cryst (0)

Bacteria
Protein Name	EC#	Organism	PDB/3D Carbohydrate Ligands Resolution (Å)
mannosyl-oligosaccharide α-1,2-mannosidase (BT3990)	3.2.1.113	Bacteroides thetaiotaomicron VPI-5482	2WVX[A,B,C,D] 1.90 2WVZ[A,B,C,D] <carb_like_KIF> 2.40 2WW0[A,B,C,D,E,F,G,H] <carb_like_SWA> 2.80 2WW1[A,B,C,D] α-D-Manp-(1-2)-α-D-Manp2S-(1-1)-methyl 2.25 2WW3[A,B,C,D,E,F] α-D-Manp-(1-2)-α-D-Manp2S-(1-1)-methyl 2.10 2WZS[A,B,C,D,E,F,G,H] <carb_like_MVL> 2.25
mannosyl-oligosaccharide α-1,2-mannosidase (BT2199)	3.2.1.113	Bacteroides thetaiotaomicron VPI-5482	2WVY[A,B,C] 2.26 2WW2[A,B,C] <carb_like_SWA> 1.90
[N-glycan] (Man-1-Pi-6-Man-specific) uncapping α-mannosidase (CcGH92_5;CcMan5)	3.2.1.-	Cellulosimicrobium cellulans	2XSG[A,B] 2.00 4AQ0[A,B] <carb_like_DMJ> 2.09
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