Glycoside Hydrolase Family 8

Activities in Familychitosanase (EC 3.2.1.132); cellulase (EC 3.2.1.4); licheninase (EC 3.2.1.73); endo-1,4-β-xylanase (EC 3.2.1.8); reducing-end-xylose releasing exo-oligoxylanase (EC 3.2.1.156)
Mechanism Inverting
ClanGH-M
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseAsp (inferred)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family D
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (6671); Uniprot accession (357); PDB accession (44); 3D entries (16); cryst (1)
All (6553) Bacteria (6523) Eukaryota (12) unclassified (18) Structure (16 - 1 cryst) Characterized (76)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 66 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CUJ89_07235   Burkholderia pyrrocinia mHSR5 AXF20307.1    
 BW21_6070   Burkholderia sp. 2002721687 AJY39914.1    
 bAD24_III00495 (BcsZ)   Burkholderia sp. AD24 ASL45841.1    
 WS70_25170   Burkholderia sp. BDU6 AOJ05813.1    
 WS71_03915   Burkholderia sp. BDU8 AOJ08074.1    
 AQ610_22865   Burkholderia sp. Bp5365 MSMB43 ALX45324.1    
 BC1001_5323   Burkholderia sp. CCGE1001 ADX58704.1    
 BC1003_4098   Burkholderia sp. CCGE1003 ADN60034.1 E1TDT2  
 FAZ95_32405 (BcsZ)   Burkholderia sp. DHOD12 QCP53716.1    
 AC233_03385   Burkholderia sp. HB1 ALE53876.1    
 DCN14_21730   Burkholderia sp. IDO3 AXK65227.1    
 DM992_14605   Burkholderia sp. JP2-270 AWV00605.1    
 FFI87_006900 (BcsZ)   Burkholderia sp. KBS0801 QDW50092.1    
 MYA_1219   Burkholderia sp. KJ006 AFJ85583.1    
 A9R05_20795   Burkholderia sp. KK1 AQH01281.1    
 WS66_22080   Burkholderia sp. LA-2-3-30-S1-D2 AOI98328.1    
 WS78_04135   Burkholderia sp. MSMB0266 AOJ70721.1    
 WS86_05405   Burkholderia sp. MSMB0852 AOJ82513.1    
 WS87_10645   Burkholderia sp. MSMB0856 AOJ87101.1    
 WT60_05375   Burkholderia sp. MSMB617WGS AOK48674.1    
 WS54_18925   Burkholderia sp. NRF60-BP8 AOI78381.1    
 AYM40_05995   Burkholderia sp. OLGA172 ANB71975.1    
 AYM40_23735   Burkholderia sp. OLGA172 ANB75388.1    
 AXG89_15675   Burkholderia sp. PAMC 26561 AME26651.1    
 AX768_25460   Burkholderia sp. PAMC 28687 AMM18331.1    
 BRPE67_BCDS12440   Burkholderia sp. RPE67 BAO89158.1    
 BTHE68_30760 (WssD)   Burkholderia sp. THE68 BBU29342.1    
 BYI23_B008380   Burkholderia sp. YI23 AET91445.1    
 BSTAB16_1040 (BcsZ)   Burkholderia stabilis VBB10924.1    
 BBJ41_05185   Burkholderia stabilis ATCC BAA-67 AOR66989.1    
 BSFP_000980   Burkholderia stabilis FERMP-21014 BAX57312.1    
 BG87_3533   Burkholderia thailandensis 2002721643 AJY02959.1    
 BTQ_4077 (BcsZ)   Burkholderia thailandensis 2002721723 AHI76015.1    
 DR62_5739   Burkholderia thailandensis 2003015869 AIP67023.2    
 BTM_3644   Burkholderia thailandensis 34 AJY32183.1    
 G9462_22645 (BcsZ)   Burkholderia thailandensis BPM QIO14754.1    
 BTN_5562   Burkholderia thailandensis E254 AIT23546.1    
 DR63_4983   Burkholderia thailandensis E264 AIP29258.1    
 BTH_II0792   Burkholderia thailandensis E264 E264; ATCC 700388 ABC35458.1 Q2T760  
 BTJ_5109 (BcsZ)   Burkholderia thailandensis E444 AHI80727.1    
 A8H31_02805   Burkholderia thailandensis FDAARGOS_237 AVR06582.1    
 A8H32_26630   Burkholderia thailandensis FDAARGOS_238 AVR28457.1    
 A8H36_00760   Burkholderia thailandensis FDAARGOS_242 AWY64016.1    
 CO709_02300   Burkholderia thailandensis FDAARGOS_426 ATF32360.1    
 BTL_3574 (BcsZ)   Burkholderia thailandensis H0587 AHI67985.1    
 BTI_4062   Burkholderia thailandensis MSMB121 AGK51050.1    
 BTHA_4307   Burkholderia thailandensis MSMB59 AIS98805.1    
 BTRA_3571 (BcsZ)   Burkholderia thailandensis USAMRU Malaysia #20 AIC90387.1    
 BW23_349   Burkholderia ubonensis MSMB22 AJX18107.1    
 Bcep1808_1350   Burkholderia vietnamiensis G4 ABO54360.1 A4JDK7  
 AK36_2592   Burkholderia vietnamiensis LMG 10929 AJY05555.1    
 A4V04_12560   Burkholderiales bacterium YL45 ANU67169.1    
 BADSM9389_00510   Buttiauxella agrestis DSM 9389 BCG07433.1    
 D8682_15930   Buttiauxella sp. 3AFRM03 AYN28333.1    
 CIY_10200 (fragment)   Butyrivibrio fibrisolvens 16/4 CBK73877.1 D4J188  
 bhn_I1756   Butyrivibrio hungatei MB2003 AOZ96789.1    
 bpr_I1513   Butyrivibrio proteoclasticus B316 ADL34250.1 E0RWF2  
 SBC1_18410 (BcsZ)   Caballeronia sp. SBC1 QIN61846.1    
 SBC2_19790 (BcsZ)   Caballeronia sp. SBC2 QIE23950.1    
 NIES22_60260 (fragment)   Calothrix brevissima NIES-22 BAY65914.1    
 NIES267_61790   Calothrix parasitica NIES-267 BAY86668.1    
 NIES267_49840   Calothrix parasitica NIES-267 BAY85484.1    
 IJ00_13430   Calothrix sp. 336/3 AKG22128.1    
 NIES2100_07150   Calothrix sp. NIES-2100 BAY20971.1    
 NIES3974_02840   Calothrix sp. NIES-3974 BAZ03655.1    
 NIES4071_47950   Calothrix sp. NIES-4071 BAZ12961.1    
 NIES4101_47010   Calothrix sp. NIES-4101 BAZ38759.1    
 NIES4105_47890   Calothrix sp. NIES-4105 BAZ59107.1    
 Cal6303_3036   Calothrix sp. PCC 6303 AFZ01983.1    
 Cal7507_3086   Calothrix sp. PCC 7507 AFY33498.1    
 kuste3391 (BcsC)   Candidatus Kuenenia stuttgartiensis CAJ74153.1 Q1Q2C1  
 KsCSTR_18040   Candidatus Kuenenia stuttgartiensis CSTR1 QII11183.1    
 DAMO_0178   Candidatus Methylomirabilis oxyfera CBE67286.1 D5MID6  
 F6R98_05605 (BcsZ)   Candidatus Methylospira mobilis Shm1 QFY44955.1    
 W01_08820 (BcsZ)   Candidatus Nitrotoga sp. AM1P BBJ22955.1    
 BN940_15061   Castellaniella defragrans 65Phen CDM25456.1    
 Caci_7496   Catenulispora acidiphila DSM 44928 ACU76321.1 C7QB30  
 C1707_09865   Caulobacter flavus RHGG3 AYV46546.1    
 Cseg_3476   Caulobacter segnis ATCC 21756 ADG11906.1 D5VN33  
 B7G68_17805   Caulobacter segnis TK0059 AVQ03535.1    
 NCTC11466_04719 (BcsZ)   Cedecea lapagei NCTC11466 VEC02312.1    
 CO704_24435   Cedecea neteri FDAARGOS_392 ATF95001.1    
 CO704_24585   Cedecea neteri FDAARGOS_392 ATF95027.1    
 LH23_04800   Cedecea neteri M006 AIR59997.1    
 LK04_18270   Cedecea neteri ND02 ALV93974.1    
 LH86_04740   Cedecea neteri ND14a AIR64413.1    
 LH89_13210   Cedecea neteri ND14b AIR70116.1    
 JT31_12910   Cedecea neteri SSMD04 AIR05476.1    
 FOC35_01210   Cedecea sp. FDAARGOS_727 QIX94391.1    
 FOC35_09360 (BcsZ)   Cedecea sp. FDAARGOS_727 QIX95879.1    
 FOC35_09215   Cedecea sp. FDAARGOS_727 QIX95850.1    
 CBW24_15370   Celeribacter manganoxidans DY25 ATI43533.1    
 endo-β-1,4-glucanase (CMCase) (fragment) 3.2.1.4 Cellulomonas uda CB4 AAA23090.1 P18336  
 Clole_0527   Cellulosilyticum lentocellum DSM 5427 ADZ82264.1    
 ORF (fragment)   Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98619.1 D2KFL7  
 EKH84_05885   Cellulosilyticum sp. WCF-2 QEH67946.1    
 Z042_20780   Chania multitudinisentens RB-25 AHG21774.1    
 Z042_25430   Chania multitudinisentens RB-25 AJW28888.1    
 CscR   Chitiniphilus shinanonensis SAY3 BAK53936.1    
 HF324_03070   Chitinophaga sp. 1303 QJB36892.1    
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