Glycoside Hydrolase Family 8

Activities in Familychitosanase (EC 3.2.1.132); cellulase (EC 3.2.1.4); licheninase (EC 3.2.1.73); endo-1,4-β-xylanase (EC 3.2.1.8); reducing-end-xylose releasing exo-oligoxylanase (EC 3.2.1.156)
Mechanism Inverting
ClanGH-M
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseAsp (inferred)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family D
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (3918); Uniprot accession (356); PDB accession (31); 3D entries (13); cryst (1)
All (3804) Bacteria (3775) Eukaryota (11) unclassified (18) Structure (13 - 1 cryst) Characterized (75)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 38 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 endo-β-1,4-glucanase C (CelC;Ccel_0730) (Cel8C) 3.2.1.4 [Clostridium] cellulolyticum H10 ACL75109.1
AAA73867.1
P37699 1G4L[nd]
1G4N[nd]
 xylanase (Xyn8A)   Clostridium cellulovorans BAV13036.1    
 Clocel_1174   Clostridium cellulovorans 743B ADL50930.1 D9SUM5  
 Clocl_1055   [Clostridium] clariflavum DSM 19732 AEV67732.1    
 A7L45_08740   Clostridium estertheticum subsp. estertheticum DSM 8809 APC40148.1    
 endo-β-1,4-glucanase B (CelB) (Cel8A) 3.2.1.4 Clostridium josui BAA04078.1
BAI52925.1
D1MX94
P37701
 
 CSACC_14730   Clostridium saccharobutylicum BAS/B3/SW/136 AQR99664.1    
 CLSA_c14770   Clostridium saccharobutylicum DSM 13864 AGX42477.1    
 CLOSACC_14730   Clostridium saccharobutylicum NCP 195 AQS13650.1    
 CLOSC_14650   Clostridium saccharobutylicum NCP 200 AQR89762.1    
 CLOBY_15220   Clostridium saccharobutylicum NCP 258 AQS09395.1    
 Cspa_c48550   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF58608.1    
 CLSAP_46230   Clostridium saccharoperbutylacetonicum N1-504 AQR97299.1    
 Clo1100_2907   Clostridium sp. BNL1100 AEY67059.1    
 Clo1100_1820   Clostridium sp. BNL1100 AEY66030.1    
 Clo1100_0977   Clostridium sp. BNL1100 AEY65232.1    
 BGI42_06235 (fragment)   Clostridium taeniosporum 1/k AOR23354.1    
 B5M06_14625   Comamonas kerstersii 8943 AQZ99300.1    
 A9D14_15490   Croceicoccus marinus E4A9 ARU17764.1    
 AFK62_19105   Cronobacter condimenti 1330 LMG 26250 ALB64489.1    
 AFK67_19735   Cronobacter dublinensis subsp. dublinensis LMG 23823 ALB68591.1    
 AFK66_000895   Cronobacter malonaticus LMG 23826 ALX76836.1    
 AFK63_19510   Cronobacter muytjensii ATCC 51329 ALB72673.1    
 ORF4   Cronobacter sakazakii CAM32315.1 A4H2S1  
 CSK29544_01126   Cronobacter sakazakii ATCC 29544 AKE94087.1    
 ESA_04206   Cronobacter sakazakii ATCC BAA-894 ABU79386.1 A7MKP0  
 P262_00262   Cronobacter sakazakii CMCC 45402 AHB68544.1    
 AFK64_19215   Cronobacter sakazakii NCTC 8155 ALB52586.1    
 CSSP291_19490   Cronobacter sakazakii SP291 AGE88461.1    
 Ctu_40320 (BcsZ)   Cronobacter turicensis z3032 CBA34356.1    
 AFK65_18835   Cronobacter universalis NCTC 9529 ALB56622.1    
 RR42_s3454   Cupriavidus basilensis 4G11 AJG25030.1    
 CR3_1798   Cupriavidus gilardii CR3 ALD91016.1    
 Rmet_2251   Cupriavidus metallidurans CH34 ABF09130.1 Q1LL46  
 C3Z06_23875   Cupriavidus metallidurans Ni-2 AVA36350.1    
 CNE_2c13860 (Bcsz2)   Cupriavidus necator N-1 AEI80349.1    
 CNE_2c05370   Cupriavidus necator N-1 AEI79518.1    
 BJN34_24635   Cupriavidus necator NH9 AQV97052.1    
 Reut_B3526   Cupriavidus pinatubonensis JMP134 AAZ62884.1 Q46VF0  
 BKK80_26175   Cupriavidus sp. USMAA1020 AOZ09288.1    
 BKK79_32050   Cupriavidus sp. USMAA2-4 AOY96246.1    
 BKK81_30180   Cupriavidus sp. USMAHM13 AOZ03349.1    
 RALTA_B0291   Cupriavidus taiwanensis LMG 19424 CAP63489.1 B2AI90  
 GA0004736_1619   Curtobacterium sp. 9128 SBN62713.1    
 BJK06_02910   Curtobacterium sp. BH-2-1-1 AOX64864.1    
 CYFUS_009083   Cystobacter fuscus DSM 52655 ATB43603.1    
 CHU_3440   Cytophaga hutchinsonii ATCC 33406 ABG60674.1 Q11PI9  
 CHU_1075   Cytophaga hutchinsonii ATCC 33406 ABG58352.1 Q11W64  
 CHU_1240   Cytophaga hutchinsonii ATCC 33406 ABG58512.1 Q11VQ4  
 CHU_3727   Cytophaga hutchinsonii ATCC 33406 ABG60960.1 Q11NQ3  
 CHU_3441   Cytophaga hutchinsonii ATCC 33406 ABG60675.1 Q11PI8  
 CHU_2852   Cytophaga hutchinsonii ATCC 33406 ABG60100.1 Q11R64  
 AKL17_3068 (fragment)   Defluviimonas alba cai42 AMY70301.1    
 AKL17_3069 (fragment)   Defluviimonas alba cai42 AMY70302.1    
 AKL17_1358 (fragment)   Defluviimonas alba cai42 AMY68613.1    
 Dgeo_2684 + Dgeo_2687   Deinococcus geothermalis DSM 11300 ABF44117.1
ABF44120.1
   
 endoxylanase (Xyn8)   Deinococcus geothermalis MC3-4A AKN19923.1    
 Desac_0399   Desulfobacca acetoxidans DSM 11109 AEB08288.1    
 UWK_01358   Desulfocapsa sulfexigens DSM 10523 AGF77919.1    
 Desaci_2493   Desulfosporosinus acidiphilus SJ4 AFM41439.1    
 XM25_04015   Devosia sp. H5989 AKR54986.1    
 Dd1591_4079   Dickeya chrysanthemi Ech1591 ACT08877.1 C6CQ00  
 endoglucanase 8Y (Cel8Y) 3.2.1.4 Dickeya chrysanthemi PY35 AAG49556.1 Q9APJ5  
 endo-β-1,4-glucanase Y (CelY) 3.2.1.4 Dickeya dadantii 3937 AAA24818.1
ADM96331.1
P27032  
 DDI_4127   Dickeya dianthicola RNS04.9 ATO35295.1    
 CVE23_21670   Dickeya fangzhongdai DSM 101947 ATZ96349.1    
 Dd703_3891   Dickeya paradisiaca Ech703 ACS87644.1 C6C635  
 BJD21_12795   Dickeya solani D s0432-1 AUH09261.1    
 A4U42_08240   Dickeya solani IPO 2222 ANE75325.1    
 BJJ98_12760   Dickeya solani PPO 9019 AUH13234.1    
 D083_2376   Dickeya solani RNS 08.23.3.1.A AUC42725.1    
 W909_19635   Dickeya zeae EC1 AJC68171.1    
 Dd586_4057   Dickeya zeae Ech586 ACZ78883.1 D2BZL1  
 C1O30_20545   Dickeya zeae MS2 AUQ27285.1    
 FH5T_02230   Draconibacterium orientale FH5 AHW58796.1    
 HY57_11235   Dyella japonica A8 AIF47798.1    
 ETEE_1613   Edwardsiella anguillarum ET080813 AIJ08062.1    
 A9798_00550   Edwardsiella hoshinae ATCC 35051 AOV95576.1    
 NT01EI_3757   Edwardsiella ictaluri 93-146 ACR70884.1 C5BB42  
 DBV23_08830   Edwardsiella ictaluri MS-17-156 AVZ82342.1    
 B6E78_10370   Edwardsiella ictaluri RUSVM-1 ARD39732.1    
 ETAC_16135   Edwardsiella piscicida C07-087 AGH75348.1    
 BXA22_08855   Edwardsiella piscicida ETW41 ARD18430.1    
 A9797_16725   Edwardsiella piscicida S11-285 AOP44544.1    
 QY76_03590   Edwardsiella sp. EA181011 AKM46536.1    
 AAZ33_17610   Edwardsiella sp. LADL05-105 AKR79133.1    
 ETAE_3382   Edwardsiella tarda EIB202 ACY86213.1 D0ZGP2  
 ETAF_3065   Edwardsiella tarda FL6-60 ADM43168.1 E0TAQ2  
 AAW15_00475   Edwardsiella tarda FL95-01 AKH87721.1    
 CPU03_08700   Edwardsiella tarda KC-Pc-HB1 ATI64328.1    
 FA04_21435   Ensifer adhaerens Casida A ANK75282.1    
 OV14_a0267 (CelC)   Ensifer adhaerens OV14 AHK45475.1    
 ACJ69_18225   Enterobacter asburiae ATCC 35953 AMA05444.1    
 ACJ69_18265   Enterobacter asburiae ATCC 35953 AMA05451.1    
 AB190_17335   Enterobacter asburiae CAV1043 AKL02237.1    
 AB190_17375   Enterobacter asburiae CAV1043 AKL02244.1    
 A0R60_3491   Enterobacter asburiae ENIPBJ-CG1 AMX07725.1    
 A0R60_3499 (BcsZ)   Enterobacter asburiae ENIPBJ-CG1 AMX07733.1    
 DI57_19655   Enterobacter asburiae L1 AHW96540.1    
 DI57_19615   Enterobacter asburiae L1 AHW96532.1    
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