Glycoside Hydrolase Family 8

Activities in Familychitosanase (EC 3.2.1.132); cellulase (EC 3.2.1.4); licheninase (EC 3.2.1.73); endo-1,4-β-xylanase (EC 3.2.1.8); reducing-end-xylose releasing exo-oligoxylanase (EC 3.2.1.156)
Mechanism Inverting
ClanGH-M
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseAsp (inferred)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family D
External resourcesCAZypedia; PRINTS; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (3145); Uniprot accession (356); PDB accession (31); 3D entries (13); cryst (1)
All (3039) Bacteria (3014) Eukaryota (7) unclassified (18) Structure (13 - 1 cryst) Characterized (74)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 31 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 kuste3391 (BcsC)   Candidatus Kuenenia stuttgartiensis CAJ74153.1 Q1Q2C1  
 DAMO_0178   Candidatus Methylomirabilis oxyfera CBE67286.1 D5MID6  
 BN940_15061   Castellaniella defragrans 65Phen CDM25456.1    
 Caci_7496   Catenulispora acidiphila DSM 44928 ACU76321.1 C7QB30  
 Cseg_3476   Caulobacter segnis ATCC 21756 ADG11906.1 D5VN33  
 CO704_24435   Cedecea neteri FDAARGOS_392 ATF95001.1    
 CO704_24585   Cedecea neteri FDAARGOS_392 ATF95027.1    
 LH23_04800   Cedecea neteri M006 AIR59997.1    
 LK04_18270   Cedecea neteri ND02 ALV93974.1    
 LH86_04740   Cedecea neteri ND14a AIR64413.1    
 LH89_13210   Cedecea neteri ND14b AIR70116.1    
 JT31_12910   Cedecea neteri SSMD04 AIR05476.1    
 CBW24_15370   Celeribacter manganoxidans DY25 ATI43533.1    
 endo-β-1,4-glucanase (CMCase) (fragment) 3.2.1.4 Cellulomonas uda CB4 AAA23090.1 P18336  
 ORF (fragment)   Cellulosilyticum ruminicola CGMCC 1.5065 ACZ98619.1 D2KFL7  
 Z042_20780   Chania multitudinisentens RB-25 AHG21774.1    
 Z042_25430   Chania multitudinisentens RB-25 AJW28888.1    
 CscR   Chitiniphilus shinanonensis SAY3 BAK53936.1    
 CK934_12245   Chitinophaga sp. MD30 ASZ11676.1    
 Cag_0339   Chlorobium chlorochromatii CaD3 ABB27612.1 Q3ATR3  
 Plut_0993   Chlorobium luteolum DSM 273 ABB23855.1 Q3B476  
 BKX93_03925   Chromobacterium vaccinii 21-1 AOZ52713.1    
 CV2676 (BscZ)   Chromobacterium violaceum ATCC 12472 AAQ60346.1
NP_902346.1
Q7NUM1  
 CRN81_12025   Chromobacterium violaceum CV1192 ATP29065.1    
 CR207_12045   Chromobacterium violaceum CV1197 ATP32974.1    
 AL479_09635   Citrobacter amalonaticus FDAARGOS_122 AMG92715.1    
 AL524_01900   Citrobacter amalonaticus FDAARGOS_165 AMG51949.1    
 F384_19135   Citrobacter amalonaticus Y19 AKE60524.1    
 β-glucanase   Citrobacter farmeri A1 ALJ33193.1    
 CI104_01060   Citrobacter farmeri AUSMDU00008141 AST77768.1    
 BN1086_04607   Citrobacter koseri CDZ86361.1    
 CKO_04974   Citrobacter koseri ATCC BAA-895 ABV16018.1 A8ARA5  
 CEP66_08550   Citrobacter koseri FDAARGOS_287 ASE82683.1    
 CO700_21685   Citrobacter koseri FDAARGOS_393 ATF99456.1    
 ROD_42761 (BcsZ)   Citrobacter rodentium ICC168 CBG90975.1 D2TJX6  
 CITRO86_0396 (BcsZ)   Citrobacter sp. 86 SAY79482.1    
 CITRO92_1333 (BcsZ)   Citrobacter sp. 92 SAZ22609.1    
 Ccel_1258   [Clostridium] cellulolyticum H10 ACL75614.1 B8I0N9  
 Ccel_1298   [Clostridium] cellulolyticum H10 ACL75653.1 B8I0S8  
 endo-β-1,4-glucanase C (CelC;Ccel_0730) (Cel8C) 3.2.1.4 [Clostridium] cellulolyticum H10 ACL75109.1
AAA73867.1
P37699 1G4L[nd]
1G4N[nd]
 xylanase (Xyn8A)   Clostridium cellulovorans BAV13036.1    
 Clocel_1174   Clostridium cellulovorans 743B ADL50930.1 D9SUM5  
 Clocl_1055   [Clostridium] clariflavum DSM 19732 AEV67732.1    
 A7L45_08740   Clostridium estertheticum subsp. estertheticum DSM 8809 APC40148.1    
 endo-β-1,4-glucanase B (CelB) (Cel8A) 3.2.1.4 Clostridium josui BAA04078.1
BAI52925.1
D1MX94
P37701
 
 Clole_0527   Clostridium lentocellum DSM 5427 ADZ82264.1    
 CSACC_14730   Clostridium saccharobutylicum BAS/B3/SW/136 AQR99664.1    
 CLSA_c14770   Clostridium saccharobutylicum DSM 13864 AGX42477.1    
 CLOSACC_14730   Clostridium saccharobutylicum NCP 195 AQS13650.1    
 CLOSC_14650   Clostridium saccharobutylicum NCP 200 AQR89762.1    
 CLOBY_15220   Clostridium saccharobutylicum NCP 258 AQS09395.1    
 Cspa_c48550   Clostridium saccharoperbutylacetonicum N1-4(HMT) AGF58608.1    
 CLSAP_46230   Clostridium saccharoperbutylacetonicum N1-504 AQR97299.1    
 Clo1100_2907   Clostridium sp. BNL1100 AEY67059.1    
 Clo1100_1820   Clostridium sp. BNL1100 AEY66030.1    
 Clo1100_0977   Clostridium sp. BNL1100 AEY65232.1    
 BGI42_06235 (fragment)   Clostridium taeniosporum 1/k AOR23354.1    
 B5M06_14625   Comamonas kerstersii 8943 AQZ99300.1    
 A9D14_15490   Croceicoccus marinus E4A9 ARU17764.1    
 AFK62_19105   Cronobacter condimenti 1330 LMG 26250 ALB64489.1    
 AFK67_19735   Cronobacter dublinensis subsp. dublinensis LMG 23823 ALB68591.1    
 AFK66_000895   Cronobacter malonaticus LMG 23826 ALX76836.1    
 AFK63_19510   Cronobacter muytjensii ATCC 51329 ALB72673.1    
 ORF4   Cronobacter sakazakii CAM32315.1 A4H2S1  
 CSK29544_01126   Cronobacter sakazakii ATCC 29544 AKE94087.1    
 ESA_04206   Cronobacter sakazakii ATCC BAA-894 ABU79386.1 A7MKP0  
 P262_00262   Cronobacter sakazakii CMCC 45402 AHB68544.1    
 AFK64_19215   Cronobacter sakazakii NCTC 8155 ALB52586.1    
 CSSP291_19490   Cronobacter sakazakii Sp291 AGE88461.1    
 Ctu_40320 (BcsZ)   Cronobacter turicensis z3032 CBA34356.1    
 AFK65_18835   Cronobacter universalis NCTC 9529 ALB56622.1    
 RR42_s3454   Cupriavidus basilensis 4G11 AJG25030.1    
 CR3_1798   Cupriavidus gilardii CR3 ALD91016.1    
 Rmet_2251   Cupriavidus metallidurans CH34 ABF09130.1 Q1LL46  
 CNE_2c13860 (Bcsz2)   Cupriavidus necator N-1 AEI80349.1    
 CNE_2c05370   Cupriavidus necator N-1 AEI79518.1    
 BJN34_24635   Cupriavidus necator NH9 AQV97052.1    
 BKK80_26175   Cupriavidus sp. USMAA1020 AOZ09288.1    
 BKK79_32050   Cupriavidus sp. USMAA2-4 AOY96246.1    
 BKK81_30180   Cupriavidus sp. USMAHM13 AOZ03349.1    
 RALTA_B0291   Cupriavidus taiwanensis LMG 19424 CAP63489.1 B2AI90  
 GA0004736_1619   Curtobacterium sp. 9128 SBN62713.1    
 BJK06_02910   Curtobacterium sp. BH-2-1-1 AOX64864.1    
 CYFUS_009083   Cystobacter fuscus DSM 52655 ATB43603.1    
 CHU_3440   Cytophaga hutchinsonii ATCC 33406 ABG60674.1 Q11PI9  
 CHU_1075   Cytophaga hutchinsonii ATCC 33406 ABG58352.1 Q11W64  
 CHU_1240   Cytophaga hutchinsonii ATCC 33406 ABG58512.1 Q11VQ4  
 CHU_3727   Cytophaga hutchinsonii ATCC 33406 ABG60960.1 Q11NQ3  
 CHU_3441   Cytophaga hutchinsonii ATCC 33406 ABG60675.1 Q11PI8  
 CHU_2852   Cytophaga hutchinsonii ATCC 33406 ABG60100.1 Q11R64  
 AKL17_3068 (fragment)   Defluviimonas alba cai42 AMY70301.1    
 AKL17_3069 (fragment)   Defluviimonas alba cai42 AMY70302.1    
 AKL17_1358 (fragment)   Defluviimonas alba cai42 AMY68613.1    
 Dgeo_2684 + Dgeo_2687   Deinococcus geothermalis DSM 11300 ABF44117.1
ABF44120.1
   
 endoxylanase (Xyn8)   Deinococcus geothermalis MC3-4A AKN19923.1    
 Desac_0399   Desulfobacca acetoxidans DSM 11109 AEB08288.1    
 UWK_01358   Desulfocapsa sulfexigens DSM 10523 AGF77919.1    
 Desaci_2493   Desulfosporosinus acidiphilus SJ4 AFM41439.1    
 XM25_04015   Devosia sp. H5989 AKR54986.1    
 Dd1591_4079   Dickeya chrysanthemi Ech1591 ACT08877.1 C6CQ00  
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