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Glycoside Hydrolase Family 83

Activities in FamilyExo-α-sialidase (EC 3.2.1.18);
Mechanism Retaining e
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton Donornot known
External resourcesCAZypedia;
Statistics GenBank accession (8387); Uniprot accession (13); PDB accession (59); 3D entries (17); cryst (0)
Summary
Download GH83 (6053) Taxonomic display Structure (17) Characterized (7)
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Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 hemagglutinin-neuraminidase protein (HN)   Human parainfluenza virus 2 BAE00055.1
BAE95189.1
BAE95190.1
BAE95191.1
BAE95192.1
BAE95193.1
BAE95194.1		    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 2 AFL71170.1
AFL71173.1
AFL71185.1
AFL71186.1
AFL71189.1
AFL71190.1
AFL71192.1		    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 2 AFL71171.1
AFL71172.1
AFL71175.1
AFL71177.1
AFL71183.1		    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 2 AFL71176.1    
 hemagglutinin-neuraminidase (HN)   Human parainfluenza virus 2 AAZ22833.1
AAZ22835.1
AAZ22837.1
AAZ22839.1		    
 hemagglutinin-neuraminidase   Human parainfluenza virus 2 (PIV2/V9412-6) AAG10684.1
AEG47355.1
AEG47356.1
AEQ39010.1
AEQ39011.1
AIG60048.1
ALM06091.1
ALM06092.1
ALM06093.1
ALM06094.1
AMH40773.1
AMH40775.1
AMH40777.1
AMT92223.1
AMT92227.1
AMT92229.1
AMT92233.1
AMT92237.1
AMT92241.1
AMT92243.1
ARB07635.1
ARB07642.1
ARB07649.1
ARB07656.1
ARB07663.1
ARB07670.1
ARB07677.1
ARB07684.1
ARB07710.1
ARB07724.1
ARB07773.1
ARB07805.1
ARB07818.1
ARB07825.1		    
 hemagglutinin-neuraminidase   Human parainfluenza virus 2 (strain Toshiba) VIRUS 2 (TOSHIBA) CAA40787.1    
 neuraminidase   Human parainfluenza virus 2 10O5 ARB07698.1    
 neuraminidase   Human parainfluenza virus 2 10P4 ARB07704.1    
 neuraminidase   Human parainfluenza virus 2 10Q5 ARB07717.1    
 neuraminidase   Human parainfluenza virus 2 11S8 ARB07737.1    
 neuraminidase   Human parainfluenza virus 2 12A2 ARB07744.1    
 neuraminidase   Human parainfluenza virus 2 12E1 ARB07628.1    
 neuraminidase   Human parainfluenza virus 2 12I5 ARB07750.1    
 neuraminidase   Human parainfluenza virus 2 12T8 ARB07798.1    
 neuraminidase   Human parainfluenza virus 2 13J3 ARB07812.1    
 neuraminidase (HN)   Human parainfluenza virus 2 HPIV2i/Zagreb.HR/38.12(2858) AMT92231.1    
 neuraminidase (HN)   Human parainfluenza virus 2 HPIV2i/Zagreb.HR/47.11(16406) AMT92219.1    
 neuraminidase (HN)   Human parainfluenza virus 2 HPIV2i/Zagreb.HR/47.11(16475) AMT92221.1    
 neuraminidase (HN)   Human parainfluenza virus 2 HPIV2i/Zagreb.HR/49.11(16971) AMT92225.1    
 neuraminidase (HN)   Human parainfluenza virus 2 HPIV2i/Zagreb.HR/50.12(3257) AMT92235.1    
 neuraminidase (HN)   Human parainfluenza virus 2 HPIV2i/Zagreb.HR/51.12(3316) AMT92239.1    
 hemagglutinin-neuramindase (HN)   Human parainfluenza virus 2 Riyadh 105/2009 ADO60289.1
AEQ39009.1		    
 HN glycoprotein   Human parainfluenza virus 4a QWY12924.1    
 HN glycoprotein   Human parainfluenza virus 4a QWY12917.1    
 hemagglutinin-neuramindase, partial (HN) (fragment)   Human parainfluenza virus 4a AIA25474.1    
 hemagglutinin-neuraminidase   Human parainfluenza virus 4a (strain Toshiba) VIRUS 4A (TOSHIBA) AAA46799.1
BAJ11746.1		    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 1461-Yamagata-2010 BAM62820.1    
 neuraminidase   Human parainfluenza virus 4a 2018_9717 QQY99230.1    
 neuraminidase   Human parainfluenza virus 4a 2018_9868 QQY99244.1    
 neuraminidase   Human parainfluenza virus 4a 2019_0407 QQY99291.1    
 neuraminidase   Human parainfluenza virus 4a 2019_0532 QQY99308.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2132-Yamagata-2011 BAM62800.1
AGU90036.1
AHJ40478.1
AQX36831.1
AQX36851.1
AWD85192.1
AWD85195.1
AWD85197.1
AWD85200.1
QEG03836.1
QEG03850.1
QEG03857.1
QEG03864.1
QEL52765.1
QEO75962.1
QEO75995.1
QQY99268.1
UFM57023.1
UFM57024.1
UFM57025.1
UFM57026.1
UFM57027.1
UFM57028.1
UFM57029.1
UMB52246.1
UMB52261.1
UTM74153.1
WCF97264.1
WCF97271.1
WCF97278.1		    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 222-Yamagata-2010 BAM62819.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2235-Yamagata-2011 BAM62821.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2265-Yamagata-2011 BAM62801.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2526-Yamagata-2011 BAM62822.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2532-Yamagata-2011 BAM62824.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2555-Yamagata-2011 BAM62804.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2582-Yamagata-2011 BAM62823.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2594-Yamagata-2011 BAM62825.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2620-Yamagata-2011 BAM62802.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2629-Yamagata-2011 BAM62805.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 2679-Yamagata-2011 BAM62803.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4a 321-Yamagata-2010 BAM62818.1    
 HN protein   Human parainfluenza virus 4b ACF59816.1    
 HN protein   Human parainfluenza virus 4b (68-333) BAA22192.1
BAJ11753.1		    
 neuraminidase   Human parainfluenza virus 4b 04-13 AFB82777.1
AIT16061.1
ARB07385.1
ARB07691.1
ARB07730.1
ARK08574.1
ARX98258.1
BAM62807.1
BAM62809.1
BAM62812.1
BAM62813.1
BAM62814.1
BAM62815.1
BAM62816.1
BAM62817.1
QEG03843.1
QEG03871.1
QQY99275.1
UFM57031.1
UTM74146.1
UTM74160.1
UTM74167.1		    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4b 2238-Yamagata-2011 BAM62806.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4b 2413-Yamagata-2011 BAM62808.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4b 2551-Yamagata-2011 BAM62810.1    
 neuraminidase (HN) (fragment)   Human parainfluenza virus 4b 2676-Yamagata-2011 BAM62811.1    
 neuraminidase (HN)   Human parainfluenza virus 4b Henan/269/2018 UFM57030.1    
 neuraminidase   Human parainfluenza virus 4b vzhpiv41 UOQ23324.1    
 Hpv1gp09 (HN)   Human respirovirus 1 AIG60058.1    
 HN glycoprotein   Human respirovirus 1 ANY58923.1    
 HN glycoprotein   Human respirovirus 1 ANY58932.1    
 HANA   Human respirovirus 1 BAA05487.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38666.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38664.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38658.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38659.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38661.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38663.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38665.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38667.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38660.1    
 neuraminidase (HN)   Human respirovirus 1 AVM38662.1    
 neuraminidase (HN)   Human respirovirus 1 AWD84834.1
AWD84842.1
AWD84848.1
AWD84855.1		    
 neuraminidase (HN) (fragment)   Human respirovirus 1 AWD84863.1    
 neuraminidase (HN) (fragment)   Human respirovirus 1 AWD84827.1    
 neuraminidase (HN) (fragment)   Human respirovirus 1 AWD84829.1    
 neuraminidase (HN)   Human respirovirus 1 AWD84859.1    
 neuraminidase (HN) (fragment)   Human respirovirus 1 AWD84821.1    
 neuraminidase (HN) (fragment)   Human respirovirus 1 AWD84825.1    
 neuraminidase (HN)   Human respirovirus 1 AXA52695.1    
 neuraminidase (HN)   Human respirovirus 1 AXR70621.1    
 HN glycoprotein   Human respirovirus 1 AYC76682.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99889.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99862.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99895.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99880.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99871.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99888.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99876.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99868.1
QHB49163.1		    
 neuraminidase (HN)   Human respirovirus 1 ATI99882.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99883.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99873.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99893.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99892.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99877.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99869.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99860.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99891.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99886.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99872.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99879.1    
 neuraminidase (HN)   Human respirovirus 1 ATI99865.1
QHB49162.1		    
 neuraminidase (HN)   Human respirovirus 1 ATI99875.1    
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