Glycoside Hydrolase Family 83

Activities in Familyneuraminidase (EC 3.2.1.18)
Mechanism retaining
ClanGH-E
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/BaseTyr+Glu
Catalytic Proton Donornot known
Statistics GenBank accession (3531); Uniprot accession (424); PDB accession (35); 3D entries (12); cryst (0)
All (1777) Viruses (1776) unclassified (1) Structure (12) Characterized (57)
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 hemaglutinin-neuraminidase 3.2.1.18 Avian avulavirus 1 (B1(SEPRL)) AAC55047.1
AAK55551.1
AAO95266.1
AAQ77501.1
ABZ80390.1
Q83846
Q91AH7
 
 hemagglutinin-neuraminidase 3.2.1.18 Avian avulavirus 1 (B1-HITCHNER/47) AAA46668.1 P12559  
 hemagglutinin-neuraminidase 3.2.1.18 Avian avulavirus 1 (BEAUDETTE C/45). AAA46660.1
AAG30929.1
CAA00289.1
CAA27880.1
P32884
Q71SA4
 
 hemagglutinin-neuraminidase 3.2.1.18 Avian avulavirus 1 (KENSAS) AAF19984.1 Q9Q2W5 1E8T[A,B]
1E8U[A,B]
1E8V[A,B]
1USR[A,B]
1USX[A,B,C]
 hemaglutinin-neuraminidase 3.2.1.18 Avian avulavirus 1 (VACCINE 1 (B1 TYPE)) AAC55041.1 Q83842  
 hemagglutinin-neuraminidase 3.2.1.18 Avian avulavirus 1 (VACCINE 5 (B1 TYPE)) AAC55045.1 Q83845  
 hemagglutinin-neuraminidase 3.2.1.18 Avian avulavirus 1 (various strains) AAA46669.1
AER92752.1
AER92758.1
AER92763.1
AER92767.1
AER92769.1
AEU17156.1
AEU17157.1
AEU17159.1
AEU17160.1
AEU17161.1
AEU17163.1
AEU17164.1
AEU17166.1
AEU17169.1
AEU17170.1
AEU17172.1
AEU17173.1
AEU17174.1
AEU17175.1
AEV40799.1
AEV40802.1
AEV40804.1
AEV40806.1
AEV40808.1
AEV40812.1
AEW24450.1
AEW24462.1
AEW24468.1
AEW24474.1
AEW24480.1
AEX01230.1
AEY80140.1
AEY85016.1
AEY85022.1
AEZ00706.1
AEZ00712.1
AEZ00718.1
AEZ00724.1
AEZ49612.1
AFA36068.1
AFA36074.1
AFA36080.1
AFA36086.1
AFH08720.1
AFH08726.1
AFI58044.1
AFN37166.1
AFN61273.1
AFN61279.1
AFO62738.1
AFO62741.1
AFO62742.1
AFO62743.1
AFO62744.1
AFO83584.1
AFP65855.1
AFP86351.1
AFQ36610.1
AFQ36611.1
AFQ36612.1
AFQ36613.1
AFQ36614.1
AFQ36615.1
AFQ36616.1
AFQ36617.1
AFQ36618.1
AFQ36619.1
AFQ36620.1
AFQ36621.1
AFQ36622.1
AFQ36623.1
AFQ36624.1
AFQ36625.1
AFQ36626.1
AFQ36627.1
AFQ37785.1
AFQ37791.1
AFQ37797.1
AFQ37803.1
AFQ37809.1
AFQ37815.1
AFQ37821.1
AFQ37827.1
AFQ37833.1
AFQ37839.1
AFS50106.1
AFS50112.1
AFS50118.1
AFS64499.1
AFS95134.1
AFU34345.1
AFV34052.1
AFV46310.1
AFV46445.1
AFV46455.1
AFV96176.1
AFW90705.1
AFX59323.1
AFX59324.1
AFX82709.1
AFX98110.1
AFY07433.1
AFZ62612.1
AFZ62613.1
AFZ62614.1
AFZ62617.1
AFZ62618.1
AFZ62619.1
AFZ62620.1
AGB06244.1
AGE09715.1
AGG37834.1
AGG37836.1
AGG37838.1
AGG37840.1
AGG37842.1
AGH20661.1
AGK24575.1
AGL09067.1
AGL09085.1
AGL09091.1
AGL09103.1
AGL09109.1
AGL09115.1
AGL09127.1
AGL09133.1
AGL09139.1
AGL09145.1
AGL09151.1
AGL09157.1
AGL09163.1
AGL09169.1
AGL09175.1
AGL09181.1
AGL09187.1
AGN32802.1
AGO50491.1
AGT03838.1
AGT03839.1
AGT03841.1
AGT03844.1
AGT03847.1
AGT03848.1
AGT03849.1
AGT03850.1
AGT03851.1
AGT03852.1
AGT03853.1
AGT03855.1
AGT03856.1
AGT03857.1
AGT03858.1
AGT03859.1
AGT03860.1
AGT03862.1
AGT03864.1
AGT03865.1
AGT03868.1
AGT03869.1
AGT03870.1
AGT03871.1
AGT03872.1
AGT03873.1
AGT03875.1
AGT03876.1
AGT03877.1
AGT03879.1
AGT03882.1
AGT03883.1
AGT03884.1
AGT03886.1
AGT03890.1
AGT03891.1
AGT03893.1
AGT03896.1
AGT03897.1
AGT03898.1
AGT03899.1
AGT03900.1
AGT03901.1
AGT63108.1
AGT63109.1
AGT95962.1
AGU69386.1
AGU99212.1
AGU99214.1
AGW43224.1
AGW43225.1
AGW43226.1
AGW43227.1
AGW43228.1
AGW43229.1
AGW43230.1
AGW43231.1
AGW43232.1
AHF22096.1
AHF22102.1
AHF58482.1
AHG26219.1
AHG52041.1
AHG59381.1
AHG59381.2
AHH24252.1
AHI95763.1
AHJ57315.1
AHL45167.1
AHL45169.1
AHL45170.1
AHL45172.1
AHL45174.1
AHL45175.1
AHL45177.1
AHL45178.1
AHL45180.1
AHL45181.1
AHL45182.1
AHL45183.1
AHL45184.1
AHL
P12553  
 hemagglutinin-neuraminidase 3.2.1.18 Avian avulavirus 2 (CHICK/CALIFORNIA/YUCAIPA/56) BAA03119.1
ACA49109.1
ADO64219.2
ADO64222.2
ADO64223.2
ANO39180.1
ANO39188.1
ANO39196.1
BAW94626.1
BAW94633.1
Q65033  
 hemagglutinin-neuraminidase 3.2.1.18 Avian avulavirus 4 (DUCK/HK/D3/75) BAA03120.1
ACF60578.1
ACJ06715.1
AEP44006.1
AEP44018.1
AFP89383.1
AFX60882.1
AFY10787.1
AFY10791.1
AFY10795.1
AFY10799.1
AFY10803.1
AGE32280.1
ANV82504.1
AQZ26705.1
Q65034  
 hemagglutinin-neuraminidase 3.2.1.18 Bovine respirovirus 3 ABZ85924.1
AEU04140.1
AGA96115.1
AHZ90087.1
AHZ90093.1
AHZ90099.1
AHZ90105.1
AHZ90111.1
AHZ90117.1
AKR16150.1
ALS46557.1
AMQ67304.1
ANB82460.1
ANE23765.1
ANE23765.1
ANE23766.1
ANE23766.1
ANE23767.1
ANE23767.1
ANE23768.1
ANE23768.1
ANE23770.1
ANE23770.1
ANE23771.1
ANE23771.1
ANE23772.1
ANE23772.1
ANE23773.1
ANE23773.1
ANE23774.1
ANE23774.1
ANE23775.1
ANE23775.1
ANE23776.1
ANE23776.1
ANE23778.1
ANE23778.1
ANE23779.1
ANE23779.1
ANE23780.1
ANE23780.1
ANE23781.1
ANE23781.1
ANE23782.1
ANE23782.1
ANE23783.1
ANE23783.1
ANE23784.1
ANE23784.1
ANE23785.1
ANE23785.1
ANE23786.1
ANE23786.1
ANE23787.1
ANE23787.1
ANE23788.1
ANE23788.1
ANG56431.1
ANG56432.1
ANG56433.1
ANG56434.1
ANG56435.1
ANG56436.1
ANG56438.1
ANG56439.1
ANG56440.1
ANG56441.1
ANG56442.1
ANG56443.1
ANG56445.1
ANG56446.1
ANG56447.1
ANG56448.1
ANG56449.1
ANG56450.1
ANG56452.1
ANG56453.1
ANG56454.1
ANG56455.1
ANG56456.1
API64901.1
API64902.1
API64903.1
API64904.1
API64905.1
API64906.1
API64907.1
API64908.1
BAA12218.1
BAM72621.1
BAM72627.1
BAP75932.1
BAU70582.1
BAV91468.1
BAW15932.1
BAW83503.1
BAW83504.1
BAW83505.1
BAW83506.1
BAW83507.1
BAW83508.1
BAW83509.1
CAA68298.1
P06167  
 hemagglutinin-neuraminidase 3.2.1.18 Bovine respirovirus 3 (KANSAS/15626/84) AAF28258.1
NP_037645.1
Q9J7D7  
 hemagglutinin-neuraminidase 3.2.1.18 HPIV-1 (human/Washington/1957) 1 VIRUS (WASHINGTON/1957) AAA46798.1
BAK09330.1
P16071  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza 3 virus (strain AUS/124854/74) 3 VIRUS (AUS/124854/74) AAA46847.1 P12561  
 hemagglutinin-neuraminidase (hPIV-3 HN) 3.2.1.18 Human parainfluenza 3 virus (strain NIH 47885) AAA46846.1
ACS10163.1
AET35008.1
AGW48004.1
AGW48007.1
P08492 4MZA[A,B]
4MZE[A,B]
4XJQ[A,B]
4XJR[A,B]
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza 3 virus (strain TEX/12677/83) 3 VIRUS (TEX/12677/83) AAA46851.1 P12564  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza 3 virus (strain TEX/545/80) 3 VIRUS (TEX/545/80) AAA46849.1 P12562  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza 3 virus (strain TEX/9305/82) 3 VIRUS (TEX/9305/82) AAA46850.1 P12563  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza 3 virus (strain WASH/1511/73) 3 VIRUS (WASH/1511/73) AAA46844.1
BAA32574.1
P12566  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza 3 virus (strain WASH/641/79) 3 VIRUS (WASH/641/79) AAA46848.1 P12565  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza virus 2 (PIV2/V9412-6) AAG10684.1
AEG47355.1
AEG47356.1
AEQ39010.1
AEQ39011.1
AIG60048.1
ALM06091.1
ALM06092.1
ALM06093.1
ALM06094.1
AMH40773.1
AMH40775.1
AMH40777.1
AMT92223.1
AMT92227.1
AMT92229.1
AMT92233.1
AMT92237.1
AMT92241.1
AMT92243.1
ARB07635.1
ARB07642.1
ARB07649.1
ARB07656.1
ARB07663.1
ARB07670.1
ARB07677.1
ARB07684.1
ARB07710.1
ARB07724.1
ARB07773.1
ARB07805.1
ARB07818.1
ARB07825.1
Q9E7N1  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza virus 2 (strain Toshiba) VIRUS 2 (TOSHIBA) CAA40787.1 P25466  
 hemagglutinin-neuramindase (HN) 3.2.1.18 Human parainfluenza virus 2 Riyadh 105/2009 ADO60289.1
AEQ39009.1
E3ULT3  
 hemagglutinin-neuraminidase 3.2.1.18 Human parainfluenza virus 4a (strain Toshiba) VIRUS 4A (TOSHIBA) AAA46799.1
BAJ11746.1
P21526  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 CAA26576.1
AEG47353.1
AEG47354.1
AFP49359.1
AFP49365.1
AFP49371.1
AFP49383.1
AFP49395.1
AFP49401.1
AFP49419.1
AFP49424.1
AFP49431.1
AFP49437.1
AFP49443.1
AFP49449.1
AFP49455.1
AFP49461.1
AFP49467.1
AFP49473.1
AFP49479.1
AFP49485.1
AFP49491.1
AFP49497.1
AFP49503.1
AFP49515.1
AFP49521.1
AFP49527.1
AFP49539.1
AFP49557.1
AFP49563.1
AFP49575.1
AFP49582.1
AGT75066.1
AGT75076.1
AGT75089.1
AGT75109.1
AGT75114.1
AGT75119.1
AGT75129.1
AGT75149.1
AGT75159.1
AGW50967.1
AGW50977.1
AGW50987.1
AGW50997.1
AGW51027.1
AGW51037.1
AKS39781.1
AKS39782.1
AKS39783.1
AKS39784.1
AKS39785.1
AKS39786.1
AKS39787.1
AKS39788.1
AKS39789.1
AKS39790.1
AKS39791.1
AKS39792.1
AKS39793.1
AKS39794.1
AKS39795.1
AKS39796.1
AKS39797.1
AKS39798.1
AKS39799.1
AKS39800.1
AKS39801.1
AKS39802.1
ALM06090.1
BAP90830.1
BAP90834.1
P06863  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 CAA27274.1 P04853  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 (MIL-51/91) AAB17173.1
BAK41441.1
BAK41442.1
BAK41487.1
BAK41491.1
Q98008  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 (MIL-52/91) AAB17174.1 Q98009  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 (MIL-53/91) AAB17175.1 Q98010  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 (MIL-55/91) AAB17177.1 Q98012  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 (MIL-58/91) AAB17178.1 Q98013  
 hemagglutinin-neuraminidase 3.2.1.18 Human respirovirus 1 (MIL-62/91) AAB17181.1 Q98016  
 hemagglutinin-neuraminidase protein (HN) 3.2.1.18 Menangle virus AAK62284.1 Q91MJ8  
 hemagglutinin-neuraminidase 3.2.1.18 Mumps virus (EUROPE-1) CAA67378.1 Q83651  
 hemagglutinin-neuraminidase 3.2.1.18 Mumps virus GLOUC1/UK96 AAG37832.1 Q9DQA1  
 hemagglutinin-neuraminidase 3.2.1.18 Mumps virus Miyahara vaccine (MIYAHARA VACCINE) BAG84572.1
BAA94390.1
BAJ15035.1
CAA33358.1
P11235 5B2C[A,B]
5B2D[A,B]
 hemagglutinin-neuraminidase 3.2.1.18 Mumps virus strain RW (RW) AAA46609.1
AEB92303.1
P10866  
 hemagglutinin-neuraminidase 3.2.1.18 Mumps virus strain SBL-1 (SBL-1) AAA74751.1 P19762  
 hemagglutinin-neuraminidase 3.2.1.18 Murine respirovirus AAB06288.1
AAB06200.1
AAB06282.1
AAB06294.1
AKA58531.1
ANQ45728.1
BAN84659.1
BAN84665.1
   
 hemagglutinin-neuraminidase 3.2.1.18 Murine respirovirus HAMAMATSU BAB20025.1
BAC07511.1
BAC79131.1
BAC79139.1
BAC79147.1
   
 hemagglutinin-neuraminidase (HN) 3.2.1.18 Newcastle disease virus (STRAIN AUSTRALIA-VICTORIA/32) VIRUS (AUSTRALIA-VICTORIA/32)   P12554 3T1E[A,B]
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus (STRAIN IBA/85) VIRUS (IBA/85) AAA46667.1 P35742  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus (STRAIN LAS/46) VIRUS (LAS/46) AAA46659.1
ACT34824.1
ACT34831.1
ACT34835.1
AEL75044.1
AEO72344.1
P35743  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus B1 AAG36979.1 Q91UL0  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus CHI/85 VIRUS (CHI/85) AAA46666.1
ACD44598.1
P35740  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus Miyadera/51 VIRUS (MIYADERA/51) AAA46674.1 P12557  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus strain D26/76 VIRUS (D26/76) AAA46638.1
AAA46655.1
ACM45086.1
ACT22814.1
ACT22820.1
ACT22826.1
ACT22832.1
ACT22886.1
ACT22892.1
ACT22898.1
ACT22904.1
ACT34822.1
ADF59224.1
ADF59235.1
P12555  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus strain HER/33 VIRUS (HER/33) AAA46664.1 P35741  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus strain Italien/45 VIRUS (ITALIEN/45) AAA46671.1
ADQ64402.1
ADU52867.1
P12556  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus strain Queensland/66 VIRUS (QUEENSLAND/66) AAA46654.1
ACT34823.1
P13850  
 hemagglutinin-neuraminidase 3.2.1.18 Newcastle disease virus Ulster/67 VIRUS (ULSTER/67) BAA00174.1 P12558 4FZH[A,B,C,D]
 hemagglutinin-neuraminidase 3.2.1.18 Sendai virus (strain Fushimi) (FUSHIMI) CAA39596.1 P19758  
 hemagglutinin-neuraminidase 3.2.1.18 Sendai virus (strain Harris) (HARRIS) AAA47810.1 P03425  
 hemagglutinin-neuraminidase 3.2.1.18 Simian virus 41 AAA47451.1
CAA45568.1
P25180  
 hemagglutinin-neuraminidase 3.2.1.18 Simian virus 5 (isolate canine/CPI+) 5 (CANINE/CPI POSITIVE)   P28884  
 hemagglutinin-neuraminidase 3.2.1.18 Simian virus 5 (isolate canine/CPI-) 5 (CANINE/CPI NEGATIVE)   P28883  
 hemagglutinin-neuraminidase 3.2.1.18 Simian virus 5 (isolate human/LN) 5 (HUMAN/LN)   P28885  
 hemagglutinin-neuraminidase F 3.2.1.18 Simian virus 5 (strain W3) 5 (W3) AAA47878.1
AAB21114.1
AAC95517.1
P04850 1Z4V[A]
1Z4W[A]
1Z4X[A]
1Z4Y[A]
1Z4Z[A]
1Z50[A]
4JF7[A,B,C,D]
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