Glycoside Hydrolase Family 7

Activities in Familyendo-β-1,4-glucanase (EC 3.2.1.4); reducing end-acting cellobiohydrolase (EC 3.2.1.176); chitosanase (EC 3.2.1.132); endo-β-1,3-1,4-glucanase (EC 3.2.1.73)
Mechanism Retaining
ClanGH-B
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family C. The cellobiohydrolases of this family act processively from the reducing ends of cellulose chains to generate cellobiose. This is markedly different from the IUBMB definition of cellobiohydrolases (EC 3.2.1.91), which act from the non-reducing ends of cellulose.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (10567); Uniprot accession (528); PDB accession (84); 3D entries (17); cryst (0)
All (5102) Bacteria (10) Eukaryota (5088) unclassified (4) Structure (17) Characterized (84)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 51 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CbhI (fragment)   Trichoderma harzianum AK289/05 CBX31939.1 E3Q0C6  
 cellobiohydrolase (CbhI) (fragment)   Trichoderma harzianum AK289/05 AEL87774.1    
 cellobiohydrolase (CbhI) (fragment)   Trichoderma harzianum AK289/05 AEL87775.1
AEQ59476.1
   
 CBH1 (fragment)   Trichoderma harzianum CCM8008 ADY89583.1    
 cellobiohydrolase   Trichoderma harzianum ETS323 AFD01232.1    
 cellobiohydrolase I (Cbh1;ThCBHI;ThCel7A) (Cel7A) 3.2.1.176 Trichoderma harzianum FP 108 / IOC-3844 AAF36391.1 Q9P8P3 2Y9L[A]
2Y9N[A]
2YOK[A]
 cellobiohydrolase, partial (Cbh1) (fragment)   Trichoderma harzianum NVTH1 AID55118.1    
 cellobiohydrolase, partial (Cbh1) (fragment)   Trichoderma harzianum NVTH2 AID55119.1    
 cellobiohydrolase   Trichoderma harzianum WF5 AIK67329.1    
 cellobiohydrolase I, partial   Trichoderma koningii AFP58843.1    
 cellobiohydrolase (Cbh1) (Cel7A) 3.2.1.176 Trichoderma koningii G-39 CAA49596.1 P00725
P62695
 
 unnamed protein product (fragment)   Trichoderma longibrachiatum CAL47738.1    
 endoglucanase I   Trichoderma longibrachiatum 3.1029 AEI71804.1    
 endoglucanase I (Egl1)   Trichoderma longibrachiatum 36MS AEC03714.1    
 endo-β-1,4-glucanase I (Egl1;EglI;TlCel7A;eCEL;E-CELTR) (Cel7A) 3.2.1.4 Trichoderma longibrachiatum CECT 2606 CAA43059.1
1920181A
Q12714  
 endoglucanase I   Trichoderma longibrachiatum FU05 ACZ34302.1 D1MGM7  
 endoglucanase I   Trichoderma longibrachiatum MKU1 AFJ54161.1    
 CBH1 (fragment)   Trichoderma pleuroticola AEQ59466.1    
 endoglucanase I (HpCel7B) (Cel7B) 3.2.1.4 Trichoderma pseudokoningii ABM90986.1 A2TDD6  
 endoglucanase I (Eg1)   Trichoderma pseudokoningii 3.3002 AEQ29501.1    
 cellobiohydrolase I / chitosanase (CBHI;Cbh1;CBH-I;TrCel7A;HjCel7A;TreCel7A) (Cel7A) 3.2.1.176
3.2.1.132
Trichoderma reesei CAH10320.1
AAE25072.1
AAR60512.1
CAF32516.1
CAF32517.1
CAF32518.1
CAR96030.1
P62694 1CEL[A,B]
1DY4[A]
1EGN[A]
1Q2B[A]
1Q2E[A,B]
2CEL[A,B]
2V3I[A]
3CEL[A]
4C4C[A]
4C4D[A]
4CEL[A,B]
4D5I[A]
4D5J[A]
4D5O[A]
4D5P[A]
4D5Q[A]
4D5V[A]
4P1H[A]
4P1J[A]
4UWT[A]
4V0Z[A]
5CEL[A]
5OA5[A,B]
5TC9[A]
6CEL[A]
7CEL[A]
8CEL[nd]
 endo-β-1,4-glucanase I (EGI;Egl1;EG-I;TrCel7B) (Cel7B) 3.2.1.4 Trichoderma reesei AAA34212.1
AAE25071.1
AAQ24882.1
AAR60514.1
ABE22093.1
CAR96034.1
CAR96035.1
P07981 1EG1[A,C]
 endoglucanase I (Egl)   Trichoderma reesei M5 ADM08177.1 E1AFV7  
 endo-β-1,4-glucanase (Egl1) 3.2.1.4 Trichoderma reesei PTCC 5142 AAX28897.1 Q5BMS5  
 glycoside hydrolase family 7 protein   Trichoderma saturnisporum AGV05126.1    
 endoglucanase I (EgI;EGI) 3.2.1.4 Trichoderma sp. SSL ACH68455.1 B5M4A3  
 cellobiohydrolase I   Trichoderma sp. XST1 ACH96125.1 B5TWC6  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Trichoderma virens UKM-1 ACF93800.1 B5ATG1  
 exocellulase   Trichoderma viride ACX42576.1 D0F0C2  
 bifunctional chitosanase-cellulase (CCBE)   Trichoderma viride ACZ06578.1
AMP44570.1
D5FY04  
 endoglucanase I (Eg1)   Trichoderma viride AEO17039.1
AMP44569.1
   
 cellobiohydrolase I / chitosanase (CBH1) 3.2.1.176
3.2.1.132
Trichoderma viride CAA37878.1 P19355  
 endo-β-1,4-glucanase I (EGI;BglI) 3.2.1.4 Trichoderma viride AS 3.3711 AAQ21382.1 Q7Z7X3  
 cellobiohydrolase I (CbhI) 3.2.1.176 Trichoderma viride AS 3.3711 AAQ76092.1 Q6UJY1  
 endoglucanase I 3.2.1.4 Trichoderma viride HK-75   Q7M4V4  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Trichoderma viride MC300-1 BAA36215.1 P19355  
 unnamed protein product   Trichophaea saccata CAD79787.1    
 AAA16YJ11FL   uncultured eukaryote CCA94937.1    
 AAA16YO07FL   uncultured eukaryote CCA94938.1    
 CBHI (fragment)   uncultured fungus ACJ53627.1 B7UC06  
 CBHI (fragment)   uncultured fungus ACJ53628.1 B7UC07  
 CBHI (fragment)   uncultured fungus ACJ53629.1 B7UC08  
 CBHI (fragment)   uncultured fungus ACJ53630.1 B7UC09  
 CBHI (fragment)   uncultured fungus ACJ53631.1 B7UC10  
 CBHI (fragment)   uncultured fungus ACJ53632.1 B7UC11  
 CBHI (fragment)   uncultured fungus ACJ53633.1 B7UC12  
 CBHI (fragment)   uncultured fungus ACJ53634.1 B7UC13  
 CBHI (fragment)   uncultured fungus ACJ53635.1 B7UC14  
 CBHI (fragment)   uncultured fungus ACJ53636.1 B7UC15  
 CBHI (fragment)   uncultured fungus ACJ53637.1 B7UC16  
 CBHI (fragment)   uncultured fungus ACJ53638.1 B7UC17  
 CBHI (fragment)   uncultured fungus ACJ53639.1 B7UC18  
 CBHI (fragment)   uncultured fungus ACJ53640.1 B7UC19  
 CBHI (fragment)   uncultured fungus ACJ53641.1 B7UC20  
 CBHI (fragment)   uncultured fungus ACJ53642.1 B7UC21  
 CBHI (fragment)   uncultured fungus ACJ53643.1 B7UC22  
 CBHI (fragment)   uncultured fungus ACJ53644.1 B7UC23  
 CBHI (fragment)   uncultured fungus ACJ53645.1 B7UC24  
 CBHI (fragment)   uncultured fungus ACJ53646.1 B7UC25  
 CBHI (fragment)   uncultured fungus ACJ53647.1 B7UC26  
 CBHI (fragment)   uncultured fungus ACJ53648.1 B7UC27  
 CBHI (fragment)   uncultured fungus ACJ53649.1 B7UC28  
 CBHI (fragment)   uncultured fungus ACJ53650.1 B7UC29  
 CBHI (fragment)   uncultured fungus ACJ53651.1 B7UC30  
 CBHI (fragment)   uncultured fungus ACJ53652.1 B7UC31  
 CBHI (fragment)   uncultured fungus ACJ53653.1 B7UC32  
 CBHI (fragment)   uncultured fungus ACJ53654.1 B7UC33  
 CBHI (fragment)   uncultured fungus ACJ53655.1 B7UC34  
 CBHI (fragment)   uncultured fungus ACJ53656.1 B7UC35  
 CBHI (fragment)   uncultured fungus ACJ53657.1 B7UC36  
 CBHI (fragment)   uncultured fungus ACJ53658.1 B7UC37  
 CBHI (fragment)   uncultured fungus ACJ53659.1 B7UC38  
 CBHI (fragment)   uncultured fungus ACJ53660.1 B7UC39  
 CBHI (fragment)   uncultured fungus ACJ53661.1 B7UC40  
 CBHI (fragment)   uncultured fungus ACJ53662.1 B7UC41  
 CBHI (fragment)   uncultured fungus ACJ53663.1 B7UC42  
 CBHI (fragment)   uncultured fungus ACJ53664.1 B7UC43  
 CBHI (fragment)   uncultured fungus ACJ53665.1 B7UC44  
 CBHI (fragment)   uncultured fungus ACJ53666.1 B7UC45  
 CBHI (fragment)   uncultured fungus ACJ53667.1 B7UC46  
 CBHI (fragment)   uncultured fungus ACJ53668.1 B7UC47  
 CBHI (fragment)   uncultured fungus ACJ53669.1 B7UC48  
 CBHI (fragment)   uncultured fungus ACJ53670.1 B7UC49  
 CBHI (fragment)   uncultured fungus ACJ53671.1 B7UC50  
 CBHI (fragment)   uncultured fungus ACJ53672.1
ADJ38339.1
ADJ38346.1
B7UC51  
 CBHI (fragment)   uncultured fungus ACJ53673.1 B7UC52  
 CBHI (fragment)   uncultured fungus ACJ53674.1 B7UC53  
 CBHI (fragment)   uncultured fungus ACJ53675.1 B7UC54  
 CBHI (fragment)   uncultured fungus ACJ53676.1 B7UC55  
 CBHI (fragment)   uncultured fungus ACJ53677.1 B7UC56  
 CBHI (fragment)   uncultured fungus ACJ53678.1 B7UC57  
 CBHI (fragment)   uncultured fungus ACJ53679.1 B7UC58  
 CBHI (fragment)   uncultured fungus ACJ53680.1 B7UC59  
 CBHI (fragment)   uncultured fungus ACJ53681.1 B7UC60  
 CBHI (fragment)   uncultured fungus ACJ53682.1 B7UC61  
 CBHI (fragment)   uncultured fungus ACJ53683.1 B7UC62  
 CBHI (fragment)   uncultured fungus ACJ53684.1 B7UC63  
 CBHI (fragment)   uncultured fungus ACJ53685.1 B7UC64  
 CBHI (fragment)   uncultured fungus ACJ53686.1 B7UC65  
 CBHI (fragment)   uncultured fungus ACJ53687.1 B7UC66  
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