Glycoside Hydrolase Family 7

Activities in Familyendo-β-1,4-glucanase (EC 3.2.1.4); reducing end-acting cellobiohydrolase (EC 3.2.1.176); chitosanase (EC 3.2.1.132); endo-β-1,3-1,4-glucanase (EC 3.2.1.73)
Mechanism Retaining
ClanGH-B
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family C. The cellobiohydrolases of this family act processively from the reducing ends of cellulose chains to generate cellobiose. This is markedly different from the IUBMB definition of cellobiohydrolases (EC 3.2.1.91), which act from the non-reducing ends of cellulose.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (10567); Uniprot accession (528); PDB accession (84); 3D entries (17); cryst (0)
All (5102) Bacteria (10) Eukaryota (5088) unclassified (4) Structure (17) Characterized (84)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 51 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CBH1 (fragment)   Pluteus petasatus DSMZ62950 AEN92164.1    
 CBH1 (fragment)   Pluteus petasatus DSMZ62950 AEN92197.1    
 Pa_1_7520   Podospora anserina S mat+ CAP60457.1
CDP23102.1
B2A8V6  
 Pa_4_1170   Podospora anserina S mat+ CAP61495.1
CDP27850.1
B2ADI0  
 Pa_5_12770 (fragment)   Podospora anserina S mat+ CAP62187.1 B2AFG8  
 Pa_4_5140   Podospora anserina S mat+ CAP67010.1
CDP28752.1
B2AQ71  
 Pa_6_11480   Podospora anserina S mat+ CAP67494.1
CDP30360.1
B2ASX1  
 Pa_3_730   Podospora anserina S mat+ CAP61105.1
CDP26556.1
B2ACE0  
 unnamed protein product   Poitrasia circinans CAD79792.1    
 cellobiohydrolase I (Cel1;CBHI)   Polyporus arcularius 69B-8 BAF80326.1 A8CED6  
 CBH1 (fragment)   Preussia sp. mg156 AEO14789.1    
 CBH1 (fragment)   Preussia sp. mg167 AEO14793.1    
 cellulase   Prorocentrum donghaiense Lu ASK39989.1    
 unnamed protein product   Pseudoplectania nigrella CAD79798.1    
 endoglucanase 3 (PgEG3) 3.2.1.4 Pseudotrichonympha grassii BAB64562.1 Q95YH3  
 endoglucanase 2 (PgEG2) 3.2.1.4 Pseudotrichonympha grassii BAB64561.1 Q95YH4  
 endoglucanase 1 (PgEG1h) 3.2.1.4 Pseudotrichonympha grassii BAB64553.1
BAB64554.1
BAB64555.1
BAB64556.1
BAB64557.1
BAB64558.1
BAB64559.1
BAB64560.1
Q95NK6
Q95P32
 
 cellulase (PgCBH-homo2A/B/C/D)   Pseudotrichonympha grassii BAB69426.1
BAB69427.1
BAB69428.1
BAB69429.1
   
 cellulase (Pgcbh-homo1)   Pseudotrichonympha grassii BAB69425.1    
 cellulase (dCel1)   Pyrocystis lunula / Crypthecodinium cohnii ADG63073.1    
 CBH1 (fragment)   Pythium intermedium DSMZ62950 AEN99787.1    
 GH7 (fragment)   Rasamsonia byssochlamydoides CBS 151.75 CDF76455.1    
 endo-β-1,4-glucanase (Egl7A)   Rasamsonia emersonii CBS 394.64 AHL20272.1
CAJ75962.1
   
 cellobiohydrolase 1 (Cbh1A;CBH IB;TeCbh1;ReCel7A) (Cel7A) 3.2.1.176 Rasamsonia emersonii IMI 392299 AAL89553.1
AAL33603.2
Q8TFL9 1Q9H[A]
3PFJ[A]
3PFX[A]
3PFZ[A]
3PL3[A]
 GH7 (fragment)   Remersonia thermophila CBS 540.69 CDF76457.1    
 cellulase (GHF7-3)   Reticulitermes flavipes AGT15838.1    
 cellulase (GHF7-5)   Reticulitermes flavipes AGT15839.1    
 cellulase (GHF7-6)   Reticulitermes flavipes AGT15840.1    
 Cell-2   Reticulitermes flavipes gut symbiont cell-2 AAY83390.1
AAY83390.2
AAY83390.3
Q462H0  
 Cell-3 (fragment)   Reticulitermes flavipes gut symbiont cell-3 AAY83391.1 Q462G9  
 Cell-4 (fragment)   Reticulitermes flavipes gut symbiont cell-4 AAY83392.1 Q462G8  
 cellobiohydrolase I, partial (Cbh1) (fragment)   Rhizopus stolonifer var. reflexus AHI87690.1    
 cellobiohydrolase I (CbhI) (fragment)   Russula emetica AEL88636.1    
 CBH1 (fragment)   Russula emetica AEQ59474.1    
 CBH1 (fragment)   Russula emetica PB1/09 ADY89604.1    
 cellobiohydrolase (CbhI) (fragment)   Russula emetica PB1/09 AEL87776.1
AEQ59462.1
   
 cellobiohydrolase I (CbhI) (fragment)   Russula paludosa AEL88635.1    
 cellobiohydrolase I (CbhI) (fragment)   Russula paludosa AEL88637.1    
 CBH1 (fragment)   Russula paludosa AEQ59464.1    
 CBH1 (fragment)   Russula paludosa BP12/09 ADY89590.1    
 CBH1 (fragment)   Russula paludosa PB12/09 ADY89603.1    
 CBHI (fragment)   Sarcoscypha occidentalis ABY61362.1 B0FQ81  
 CBHI (fragment)   Sarcoscypha occidentalis ABY61363.1
ABY61365.1
B0FQ82  
 CBHI (fragment)   Sarcoscypha occidentalis ABY61364.1 B0FQ83  
 CBH1 (fragment)   Schizophyllum commune AEO14762.1    
 cellobiohydrolase (Cel1)   Schizophyllum commune 4-40 AAX55505.1 Q58G95  
 sscle_04g033820   Sclerotinia sclerotiorum 1980 UF-70 APA08612.1    
 sscle_08g063000   Sclerotinia sclerotiorum 1980 UF-70 APA11530.1    
 sscle_14g101360   Sclerotinia sclerotiorum 1980 UF-70 APA15366.1    
 GH7 (fragment)   Scytalidium indonesiacum CBS 259.81 CDF76458.1    
 PIIN_06594   Serendipita indica DSM 11827 CCA72657.1    
 CBH1 (fragment)   Sirococcus conigenus AEQ59469.1    
 CBH1 (fragment)   Sirococcus conigenus AEQ59477.1    
 CbhI (fragment)   Sirococcus conigenus ZK26/08 CBX31957.1 E3Q0E1  
 CBH1 (fragment)   Sordaria fimicola AEN99777.1    
 CBH1 (fragment)   Stenocarpella macrospora USDA54190 AEO14791.1    
 cellobiohydrolase 1 (Cbh1)   Stereum hirsutum AFH78149.1    
 CBH1 (fragment)   Sydowia polyspora AEQ59467.1    
 CBH1 (fragment)   Sydowia polyspora AEQ59468.1    
 CBH1 (fragment)   Sydowia polyspora AEQ59470.1    
 cellobiohydrolase I / 7A (TCE0_004r00180) (Cel7A) 3.2.1.176 Talaromyces cellulolyticus Y-94 GAM33347.1    
 endo-β-1,4-glucanase 7B (TCE0_024r07350) (Cel7B) 3.2.1.4 Talaromyces cellulolyticus Y-94 GAM37432.1    
 cellobiohydrolase (XynA) 3.2.1.176 Talaromyces funiculosus IMI 378536 CAC85737.1
AAP60302.1
CAC07539.1
Q8WZJ4  
 cellobiohydrolase I (Cbh1) 3.2.1.176 Talaromyces funiculosus NCL1 ADX60067.1   4XEB[A]
 GH7   Talaromyces leycettanus CBS 398.68 CDF76456.1    
 endoglucanase (Cel7B)   Talaromyces purpureogenus AEL78899.1    
 cellobiohydrolase (Cel7A)   Talaromyces purpureogenus HZ11 AEL78900.1    
 cellobiohydrolase (Cel7A) 3.2.1.176 Thermoascus aurantiacus ALKO4242 CAM98447.1
CAD79781.1
A7WNU2  
 cellobiohydrolase (Cbh1;TaCel7A) (Cel7A) 3.2.1.176 Thermoascus aurantiacus IFO 9748 AAL83303.1
AAL16941.1
Q8TG37
Q96UR5
 
 cellobiohydrolase   Thermoascus aurantiacus RCKK AFY52523.1    
 cellobiohydrolase (CBH)   Thermoascus aurantiacus var. levisporus AAW27920.1 Q5MBA7  
 cellobiohydrolase (Cbh) (fragment)   Thermomyces lanuginosus ABR57319.1 A6YLP4  
 unnamed protein product   Thermothelomyces thermophila CAD79788.1    
 MYCTH_116157   Thermothelomyces thermophila ATCC 42464 AEO59361.1    
 MYCTH_42937   Thermothelomyces thermophila ATCC 42464 AEO53522.1    
 endo-β-1,4-glucanase (Eg7a;MtEG7a;MYCTH_111372) 3.2.1.4 Thermothelomyces thermophila ATCC 42464 AEO58196.1    
 MYCTH_109566   Thermothelomyces thermophila ATCC 42464 AEO55544.1    
 MYCTH_95095 (fragment)   Thermothelomyces thermophila ATCC 42464 AEO58824.1    
 MYCTH_97137   Thermothelomyces thermophila ATCC 42464 AEO61262.1    
 endoglucanase   Thermothelomyces thermophila CBS 117.65 AAE25067.1    
 cellobiohydrolase (Cel7A) 3.2.1.176 Thielavia australiensis CAD79782.1    
 glycoside hydrolase family 7 protein   Thielavia microspora AGV05127.1    
 cellobiohydrolase (THITE_118360) (Cel7A) 3.2.1.176 Thielavia terrestris NRRL 8126 AEO67172.1    
 THITE_134020   Thielavia terrestris NRRL 8126 AEO63146.1    
 THITE_62596   Thielavia terrestris NRRL 8126 AEO64066.1    
 THITE_54138   Thielavia terrestris NRRL 8126 AEO67140.1    
 THITE_165581   Thielavia terrestris NRRL 8126 AEO67421.1    
 CBH1 (fragment)   Thysanophora penicillioides ZK190/08 ADY89588.1    
 CBH1 (fragment)   Trametes sp. L AEN99776.1    
 CBH1 (fragment)   Trametes sp. L AEN99779.1    
 CBH1 (fragment)   Trametes sp. specimenH AEO14757.1    
 CBH1 (fragment)   Trametes sp. specimenL AEO14765.1    
 CBH1 (fragment)   Trichaptum sp. specimenJ AEO14761.1    
 CBH1 (fragment)   Trichocladium opacum DSMZ63418 AEO09145.1    
 cellobiohydrolase, partial (Cbh1) (fragment)   Trichoderma asperellum NVTA1 AID55116.1    
 cellobiohydrolase, partial (Cbh1) (fragment)   Trichoderma asperellum NVTA2 AID55117.1    
 cellobiohydrolase I (Cbh1) (fragment)   Trichoderma asperellum T203 AAS37696.1 Q6QNU7  
 Egl1 (fragment)   Trichoderma asperellum T203 AAS37698.1 Q6QNU5  
 cellobiohydrolase, partial (Cbh1) (fragment)   Trichoderma citrinoviride NVTC2 AID55115.1    
 cellobiohydrolase (Cbh1)   Trichoderma harzianum A25-2 ADH04808.1 D7RF10  
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